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Panelists discuss how the coexistence of heartdisease and chronic obstructive pulmonarydisease (COPD) requires careful management as these conditions significantly impact each other. In stable COPD, cardiovascular complications are a leading cause of mortality, whereas acute exacerbations can worsen heart function.
6, 2025 Medtronic plc hasannounced it received CE ( Conformit Europenne ) Mark for the Harmony Transcatheter Pulmonary Valve (TPV) System, a minimally invasive alternative to open-heart surgery for congenital heartdisease patients with native or surgically repaired right ventricular outflow tract (RVOT).
BackgroundCurrent evidence suggests that cardiovascular disease (CVD) plays a role in the progression of chronic obstructive pulmonarydisease (COPD). However, the relationship between CVD and the severity of COPD remains inadequately understood.
This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.
Patent ductus arteriosus (PDA) is one of the most common forms of congenital heartdisease (CHD). PDA combined with pulmonary artery aneurysm (PAA) due to IE is rare in children. Infectious endocarditis (IE) is a rare but serious complication of PDA.
Background Infants with congenital heartdisease (CHD) are clinically vulnerable to cardiac deteriorations and intercurrent infections. We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups.
BackgroundCoronary heartdisease (CHD) is a pervasive chronic condition that poses a significant threat to global health and mortality worldwide. This program was tailored to each patient, with a 50% power intensity exercise prescription derived from the results of the patient's Cardiopulmonary Exercise Testing (CPET) evaluation.
LEARNING OBJECTIVES Review the diagnostic pathway for pulmonary arterial hypertension (PAH) in congenital heartdisease (CHD). Understand and interpret right heart catheterisation data in pulmonary hypertension related to CHD. Recognise the typical presentation of PAH in patients with CHD.
Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a new study.
Objective To determine the magnitude of any excess risk of mortality and hospitalisation due to COVID-19 infection in patients with congenital heartdisease (CHD) in the UK healthcare system. Of patients with a positive COVID-19 test, patients with CHD were more likely than controls to be hospitalised (22.4%
Valvular heartdisease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RVPA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload.
Historically viewed as a secondary consequence of left-sided heartdisease or pulmonary hypertension, its pathophysiology and prognostic implications have garnered attention in recent years. Severe TR has been independently associated with increased mortality, regardless of left ventricular (LV) function or pulmonary pressures.
Pulmonary arteriovenous fistula (PAVF) is a rare disease, and its symptoms lack specificity. For patients with coronary heartdisease(CHD), hypertension and other common cardiovascular diseases, PAVF is easy t.
Journal of the American Heart Association, Ahead of Print. Survivorship from congenital heartdisease has improved rapidly secondary to advances in surgical and medical management. This is an updated report of the American Heart Association's previous publications on exercise in children.
William Boden and Bradley Maron discuss the latest advancements in managing pulmonary hypertension caused by left heartdisease. In this interview, Drs.
However, the cause and risk factors for mortality remain uncertain.MethodsThis retrospective, singlecenter study identified children with primary and secondary pulmonary vein stenosis through a cardiac catheterization database. P=0.032), and the presence of congenital heartdisease (HR, 2.4 [95% 95% CI, 2.214.1];P<0.001).
Tetralogy of Fallot TOF with pulmonary atresia Pulmonary atresia with intact interventricular septum Tricuspid atresia Double outlet right ventricle Transposition of great arteries with ventricular septal defect and pulmonary stenosis Ebstein’s anomaly of tricuspid valve In DORV and tricuspid atresia, there are also variants with increased pulmonary (..)
D-Transposition of great arteries Double outlet right ventricle without pulmonarypulmonary stenosis Taussig-Bing anomaly Total anomalous pulmonary venous return Truncus arteriosus Single ventricle (double inlet ventricle, univentricular heart)
Due to improvements in recognition and management of their multisystem disease, the long‐term survival of infants, children, and adolescents with trisomy 21 and congenital heartdisease now matches children with congenital heartdisease and no genetic condition in many scenarios.
Transcatheter pulmonary valve replacement (TPVR) has become a safe and effective alternative to surgical PVR in tetralogy of Fallot (TOF), isolated pulmonary stenosis (PS), and other congenital heartdisease (CHD) variants.
Patients with pulmonary hypertension associated with a left-right shunt include a wide spectrum of pathophysiological substrates, ranging from those characterized by pulmonary over-circulation to those with advanced pulmonary vascular disease.
Aims A proportion of patients with pulmonary arterial hypertension associated with congenital heartdisease (PAH-CHD) do not fit in the current classification.
Pulmonary arterial hypertension related to congenital heartdisease as a paradigm of complexity Pulmonary arterial hypertension related to congenital heartdisease (PAH-CHD) really represents a paradigm of complexity.
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heartdisease characterized by the inability of all pulmonary veins to connect to the left atrium. Our previous bibliometric article sum.
Its use has been approved in the adult population with heart failure and described for pulmonary hypertension (PH). Only case reports and small series have been published about its use in the paediatric population and for congenital heartdisease (CHD).
The left partial anomalous pulmonary vein connection is a rare congenital heartdisease, especially with intact atrial septum. Now we reported a case of the left superior pulmonary vein drainage to left innomi.
Transpulmonary exosomal miRs offer valuable insights into pulmonary circulation microenvironments. Using an in vitro flow model simulating the shear stress experienced by pulmonary endothelial cells, we observed a significant upregulation of miR‐21.
Background To determine the frequency of pregnancy complications and their association with the risk of cardiovascular outcomes in women with structural heartdisease (SHD).
Objective This study assessed the long-term effects of triple therapy with prostanoids on patients with pulmonary arterial hypertension associated with congenital heartdisease (PAH-CHD), as there is limited information on the safety and efficacy of this treatment approach.
Background:Neonates with complex congenital heartdisease and pulmonary overcirculation have been historically treated surgically. Pulmonary arteries grew adequately for age, and devices were easily removed without complications. However, subcohorts may benefit from less invasive procedures. At a median follow-up of 6.2
Penn Presbyterian Medical Center Becomes First Hospital in the Northeast to Adopt Advanced Robotic Technology for Heart Treatment 5. Scientists Suggest a New Method for Diagnosing HeartDiseases 6. Weight Loss Drug Linked with Reduced Need for Diuretics in Heart Failure Patients 7. Tenax Therapeutics Announces New U.S.
Objective Early risk assessment of pulmonary arterial hypertension (PAH) in patients with congenital heartdisease (CHD) is crucial to ensure timely treatment. Class Activation Mapping (CAM) images demonstrated the model's attention focused on the pulmonary artery segment.
IntroductionPrimary pulmonary vein stenosis (PVS) is a rare congenital heartdisease that proves to be a clinical challenge due to the rapidly progressive disease course and high rates of treatment complications. These 3D reconstructions were 3D printed using a clear resin ink and used in a benchtop experimental setup.
Animal studies have shown that mice with TBX1 gene mutations have smaller left pulmonary arteries compared to wild type mice, defined by a reduced left pulmonary artery (LPA) to right pulmonary artery (RPA) ratio. A single study has shown this translates to humans with 22q11 and structurally normal hearts.
A new molecular imaging technique -- 18F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression.
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundLeft heartdisease is the most common cause of pulmonary hypertension (PH) and is frequently accompanied by increases in pulmonary vascular resistance.
Sudden breathlessness at night in those with known heartdisease is usually due to collection of fluid in the lungs (pulmonary edema). Extra fluid in the body can occur due to failure of heart, kidneys, liver and rarely due to other causes.
This year saw exciting developments in the treatment of pediatric and congenital heartdisease. Transcatheter pulmonary valve replacement (TPVR) continued to dominate the field of interventional cardiology.
A scientific team has created a preclinical blood test to identify adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonarydisease (COPD).
Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heartdisease (CHD). Early management of this condition is typically dictated by the degree of pulmonary stenosis (PS) and resulting oxygen saturations.
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