DAIC

MARCH 28, 2024

milla1cf Thu, 03/28/2024 - 07:00 March 28, 2024 — Cleerly , the company on a mission to create a new standard of care to aid in the diagnosis of heart disease, shared findings from a study published online in the Journal of the American College of Cardiology: Cardiovascular Imaging on March 13, 2024. J Am Coll Cardiol.

Ischemia 110

Ischemia Chest Pain Atherosclerosis Coronary Artery Disease 110

Med Page Today

APRIL 30, 2024

(MedPage Today) -- For patients with peripheral artery disease (PAD) and chronic limb-threatening ischemia, drug-eluting stents and drug-coated balloons did not improve amputation-free survival compared with balloon angioplasty alone in the BASIL.

Peripheral Arterial Disease 65

Peripheral Arterial Disease Angioplasty Heart Disease Cancer 65

Frontiers in Cardiovascular Medicine

JANUARY 10, 2024

Coronary heart disease is a narrowing or obstruction of the vascular cavity caused by atherosclerosis of the coronary arteries, which leads to myocardial ischemia and hypoxia. At present, percutaneous coronary intervention (PCI) is an effective treatment for coronary atherosclerotic heart disease.

Heart Disease 59

Heart Disease Stent Stents Atherosclerosis 59

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 26, 2025

BACKGROUND:The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data. Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

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Ischemia Heart Disease Angina Anatomy 40

Frontiers in Cardiovascular Medicine

APRIL 3, 2025

These disruptions often lead to circadian rhythm disorders, which are now being increasingly linked to heart diseases. This review explored the potential role of REV-ERB in the cardiovascular system.

Cardiovascular Disease 40

Cardiovascular Disease Atherosclerosis Physiology Ischemia 40

Cardiovascular Diabetology

JUNE 23, 2024

demonstrate that arachidonic acid (AA) exhibits cardioprotective effects in diabetic myocardial ischemia, suggesting a departure f. In a translational study involving animal models and human subjects, Lv et al.

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Heart Disease Ischemia Diabetes 59

DAIC

FEBRUARY 13, 2024

Cleerly, a digital healthcare company focused on heart disease, has announced continued strong scientific evidence supporting the clinical utility of its products, detailing a study published online on Jan. 25, 2024 in the European Heart Journal Cardiovascular Imaging. In Press European Heart Journal CV Imag 2024.This

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Coronary Artery Disease Ischemia Atherosclerosis Cardiovascular Imaging 103

Journal of Cardiovascular Electrophysiology

NOVEMBER 15, 2024

Central illustration: In those presenting With monomorphic VT, undergoing coronary ischemia assessment was associated With improved 12-month event-free survival from the primary endpoint of VT recurrence, ICD therapy, heart failure hospitalization, and death.

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Ischemia Tachycardia Outcomes Heart Failure 40

Dr. Paddy Barrett

NOVEMBER 28, 2023

One of the most common questions I get is, “ Do I need a stent to treat my heart disease?” Ischemia Trial In an attempt to clarify this question, a similar trial was done called the Ischemia Trial, which had important differences to the Courage trial but again tried to answer a similar question 3.

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Stent Stents Heart Attack Heart attacks 52

Circulation

NOVEMBER 13, 2024

Kawasaki disease (KD), an acute self-limited febrile illness that primarily affects children <5 years old, is the leading cause of acquired heart disease in developed countries, with the potential of leading to coronary artery dilation and coronary artery aneurysms in 25% of untreated patients.

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Aneurysm Myocardial Infarction Cardiovascular Imaging Ischemia 81

Circulation

NOVEMBER 11, 2024

End-stage ischemic heart disease necessitates heart transplantation, and emerging cell therapy presents a promising solution to address donor scarcity. Disruption of gut microbiota significantly influences various diseases and treatments, including transplantation.

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Ischemia Transplant Heart Transplant Biomarkers 40

Journal of Cardiovascular Pharmacology

APRIL 1, 2024

Abstract: N-n-butyl haloperidol iodide (F2), a derivative of haloperidol developed by our group, exhibits potent antioxidative properties and confers protection against cardiac ischemia/reperfusion (I/R) injury. The protective mechanisms by which F2 ameliorates I/R injury remain obscure. Copyright © 2024 The Author(s).

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Ischemia Pharmacology Heart Disease Article 40

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology.

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Ischemia Cardiogenic Shock Aortic Stenosis 40

DAIC

MAY 16, 2024

have PAD, which increases the risk of amputation, heart attack, stroke and death. Among those ages 65 and older, nearly 50% who underwent limb amputation died within one year after surgery, according to the 2024 Heart Disease and Stroke Statistics: A Report of U.S. and Global Data From the American Heart Association.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

DAIC

DECEMBER 27, 2023

Kitsis’ pioneering research on the basic mechanisms of cardiovascular disease has opened up new therapeutic avenues for patients following a heart attack or stroke,” said Ernest Mazzaferri, MD , co-interim director of Ohio State’s Heart and Vascular Center and an interventional cardiologist.A

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Heart Attack Heart attacks Research Myocardial Infarction 111

Dr. Smith's ECG Blog

JANUARY 9, 2024

Are you confident there is no ischemia? The heart rate is about 130 bpm. The heart rate could be compatible with that of a 2:1 conducted atrial flutter. Primary VT , and the VT with tachycardia is causing ischemia with chest discomfort (supply-demand mismatch/type 2 MI)? Do you agree with this strategy?

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Tachycardia Electrophysiology Atrial Flutter Ischemia 119

Journal of Cardiovascular Pharmacology

OCTOBER 24, 2024

In the heart, autophagy is regulated mainly through mitophagy due to the metabolic changes of cardiomyocytes caused by ischemia and hypoxia. Myocardial remodeling is characterized by gradual heart enlargement, cardiac dysfunction, and extraordinary molecular changes. Copyright © 2024 Wolters Kluwer Health, Inc.

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Myocardial Infarction Ischemia Heart Failure Heart Disease 40

Dr. Smith's ECG Blog

JUNE 28, 2023

A regular wide complex tachycardia in a young patient with no history of heart disease is very likely to be AVRT. He got an MR, however that showed no scar or evidence of AVRD and he had a stress test with no evidence of inducible ischemia with almost 20 METs." Latent conduction vs. Concealed Conduction. 3 Pathways.

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Tachycardia Ultrasound Heart Disease Atrial Fibrillation 98

Dr. Smith's ECG Blog

OCTOBER 23, 2023

It was reported clinically by Sir Thomas Lewis a year later, who characterized the phenomena as occurring, “either when the heart muscle is normal but the heart rate is very fast or when there is serious heart disease and the rate is normal”.

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Tachycardia Cardiac Arrest ICU Blog 131

DAIC

MAY 14, 2024

Within the complex umbrella of cardiovascular disease, CAD is a type of heart disease that develops when the coronary arteries narrow and the heart cannot deliver enough oxygen-rich blood to the heart.

Coronary Artery Disease 111

Coronary Artery Disease Interventional Cardiology Innovation Physiology 111

Circulation: Cardiovascular Imaging

DECEMBER 6, 2023

BACKGROUND:Stress perfusion cardiovascular magnetic resonance can be performed without rest perfusion for the quantification of ischemia burden. years for major adverse cardiovascular events, with the presence of inducible ischemia by either the stress-LGE or stress-rest analysis being similar and strongly predictive (hazard ratio, 2.65;P<0.001,

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Ischemia Cardiovascular Imaging Heart Disease Circulation 40

Circulation

NOVEMBER 11, 2024

12.8%; p<0.01; (figure 1A), ischemia was found in 36.5% (95% CI; range 28.7-44.3%; 12.8%; p<0.01; (figure 1A), ischemia was found in 36.5% (95% CI; range 28.7-44.3%; Follow-up ranged from 1 to 5.2 The mean patient age was 60.8±9.5 years and 75% were male. MI and cardiovascular death was found in 9.8% (95% CI; range 6.8-12.8%;

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Diabetes Myocardial Infarction Ischemia Angina 40

MIBHS

OCTOBER 31, 2024

Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. This may result in ischemia (lack of oxygen to the heart muscle), causing parts of the heart to weaken and enlarge. Avoid excessive alcohol and drug use.

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Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

Circulation

DECEMBER 20, 2024

BACKGROUND:Cardiac fibrosis, characterized by excessive extracellular matrix (ECM) deposition in the myocardium, is an important target for heart disease treatments.Pw1(paternally expressed gene 3) is an imprinted gene expressed from the paternal allele, and de novo purine biosynthesis (DNPB) is a crucial pathway for nucleotide synthesis.

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Myocardial Infarction Ischemia Heart Disease Circulation 45

Dr. Smith's ECG Blog

JULY 14, 2023

My interpretation was: RBBB with hyperacute T-waves in V4-V6 that are all but diagnostic of LAD occlusion vs. post ROSC ischemia. Many of these patients have preexisting coronary and other forms of severe heart disease. The patient had ROSC and maintained it. A 12-lead ECG was obtained: What do you think?

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Cardiac Arrest Chest Pain Defibrillator Atrial Flutter 98

Dr. Smith's ECG Blog

JANUARY 1, 2024

His medical history includes hypertension, a decade-long battle with diabetes, ischemic heart disease, a coronary bypass graft surgery ten years ago, a diagnosis of congestive heart failure for the last five years, and a prior ICD implantation five years ago. A peak troponin level of 70 ng/L was observed.

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Tachycardia Blog Ischemia Heart Failure 112

DAIC

JANUARY 3, 2024

Traditional methods of non-invasive ischemia testing (stress EKG , stress echo, SPECT , PET , direct-to-cath) can result in false negatives 20-30 percent of the time, which can lead to undetected disease, and false positives over 50 percent of the time, which can lead to unnecessary invasive procedures. Arbab-Zadeh, Heart Int 2012.

Coronary Artery Disease 59

Coronary Artery Disease Chest Pain Plaque Technology 59

Dr. Smith's ECG Blog

MAY 29, 2017

He had some "pre-diabetes ," but no h/o hypertension, no known family history of heart disease, and he smokes about 1-2 cigarettes per day. Ischemia 3. The ST depression in precordial leads suggest still more widespread ischemia, so the exact culprit is not at all clear. He had been pain free for about an hour.

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Chest Pain Ischemia Circulation Heart Disease 52

DAIC

MARCH 3, 2025

CAD is the most common form of heart disease and remains the leading cause of death for men and women in the US, with 371,506 deaths reported in 2022 [1]. We are committed to growing the manufacturing footprint for Flyrcado to drive access for cardiac PET-enabled imaging centers throughout the US.

Coronary Artery Disease 52

Coronary Artery Disease Ischemia Exercise Hospital 52

Ken Grauer, MD

APRIL 14, 2023

These 2 findings strongly suggest significant underlying heart disease in this 90-year old patient — although without a prior tracing for comparison, we can not tell what is "new" vs "old". ECG Blog #271 — Reviews the concept of diffuse subendocardial ischemia. ECG Blog #316 — The patient died.

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Blog Chest Pain Ischemia Tachycardia 78

Heart 2023 Conference

APRIL 20, 2022

(Source: JAMA Cardiology) Patients with afib who survived an intracerebral haemorrhage had a very significant risk of cerebrovascular ischemia episodes and death in the following year, according to registry data.

Pulmonary 52

Pulmonary Hypertension AFIB COVID-19 52

Dr. Smith's ECG Blog

SEPTEMBER 26, 2023

There was a weak correlation between history of ischemic heart disease (r = 0.16, p = 0.001), percutaneous coronary intervention (r = 0.16, p = 0.001), left anterior descending artery (r = 0.12, p = 0.012) as the culprit vessel and a weak negative correlation between age (r = -0.14, p = 0.039) and chest pain.

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Chest Pain STEMI Myocardial Infarction Electrocardiogram 119

Dr. Smith's ECG Blog

JANUARY 23, 2024

Extensive conduction system abnormalities can have various causes (ischemia, genetic, infectious, amyloid, etc). Even though the primary suspicion was not ischemic heart disease, a CT angiogram was performed, and it revealed normal coronary arteries. This ruled out coronary disease as the cause of conduction system disease.

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Tachycardia Arrhythmia Heart Disease Sudden Cardiac Death 107

Stroke Journal

JANUARY 30, 2025

Cognitive impairment (CGI) is common in patients with cardiovascular diseases, contributing to morbidity and mortality, especially among people over the age of 64. Cardiogenic dementia has been suggested to characterize patients suffering from cognitive decline after heart disease.

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Dementia Myocardial Infarction Ischemia Cardiovascular Disease 40

Stroke Journal

JANUARY 30, 2025

For this study, acute symptomatic was defined as hemispheric ischemic stroke or retinal ischemia ipsilateral to the carotid stenosis, with symptom onset within 24 hours of admission. were asymptomatic and 40.2% acute symptomatic. higher (95%CI of OR 1.823.42).Conclusions:Among

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Stenosis Atherosclerosis Cholesterol Ischemia 40

Circulation

NOVEMBER 11, 2024

Topics included management of arrhythmias, structural heart disease, ischemia, cardiogenic shock, and post-procedure complications. Within the first two months of publication, the website was being accessed throughout 30+ states and 6 countries with more than 2,500 views and 1,500 unique visitors.

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Cardiogenic Shock Arrhythmia Article Ischemia 40

DAIC

OCTOBER 1, 2024

“PlaqueIQ’s underpinnings in histology is a novel approach to the field of non-invasive coronary plaque classification,” said Dr. Mark Rabbat, professor of Medicine and Radiology, director of Cardiac CT, and director of Structural Heart Disease Interventional Imaging in the Division of Cardiology at Loyola University Chicago.

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Cardiovascular Disease Plaque Quality of Life Myocardial Infarction 52