Circulation: Heart Failure

SEPTEMBER 27, 2023

Circulation: Heart Failure, Volume 16, Issue 11 , Page e010849, November 1, 2023. Mediation of the association between MMP-2 and HF was assessed by censoring participants who developed AF or coronary heart disease before HF. 1.81]), incident HF with preserved ejection fraction (1.44 [95% CI, 1.07–1.94]),

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Preserved Ejection Fraction Atrial Fibrillation Heart Failure Heart Disease 40

Frontiers in Cardiovascular Medicine

OCTOBER 10, 2024

ObjectiveTo investigate the therapeutic effect of Vericiguat combined with “new quadruple” drugs on patients with heart failure (HF).MethodsFrom Patients diagnosed with preserved ejection fraction (HFpEF) were treated with Vericiguat combined with “ARNI, BB, SGLT2i” therapy.

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Heart Failure Preserved Ejection Fraction Cardiac Function Quality of Life 52

Open Heart

APRIL 24, 2024

Introduction Heart failure (HF) incidence is increasing in older adults with high hospitalisation and mortality rates. HF with preserved ejection fraction (HFpEF) was the most common phenotype and increased significantly compared with the first period (46.3% and 29.2%, p<0.001).

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Heart Failure Preserved Ejection Fraction ACE Inhibitor Pharmacology 52

HeartRhythm

SEPTEMBER 4, 2024

Recent data suggest that sodium-glucose contransporter-2 inhibitors (SGLT2i) may mitigate development of cardiac arrythmias in patients with heart failure with preserved ejection fraction and patients with ischemic heart disease [1].

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Preserved Ejection Fraction Outcomes Heart Failure Cardiomyopathy 40

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundSystemic chronic inflammation plays a role in the pathophysiology of both heart failure with preserved ejection fraction (HFpEF) and metabolic dysfunction‐associated fatty liver disease. The study population was subdivided into non‐HF, pre‐HFpEF, and HFpEF groups at baseline. 10 mg/L) and 5.0

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Heart Failure Preserved Ejection Fraction Hospital Heart Disease 45

Dr. S. Venkatesan MD

APRIL 18, 2024

Lowering the raised LA mean pressure is a major therapeutic goal in any severely symptomatic left heart disease, whether it is valvular or myocardial disease. It is prudent to understand, that even in systolic LV failure; it is the raised LVEDP that causes the symptoms and marks the limits of exercise capacity.

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Preserved Ejection Fraction Pulmonary Congenital Heart Disease VSD 40

DAIC

FEBRUARY 29, 2024

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m.

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Aortic valve Myocardial Infarction Aortic Blood Pressure 103

DAIC

APRIL 2, 2024

Yakubu Bene-Alhasan, MD milla1cf Tue, 04/02/2024 - 12:14 April 2, 2024 — People who use e-cigarettes are significantly more likely to develop heart failure compared with those who have never used them, according to one of the largest prospective studies to date investigating possible links between vaping and heart failure.

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Heart Failure Preserved Ejection Fraction Research Risk Factors 105

Science Daily - Heart Disease

SEPTEMBER 2, 2024

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial.

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Preserved Ejection Fraction Heart Failure Hospital 126

European Journal of Heart Failure

APRIL 10, 2025

Finerenone and glycaemic status in patients with heart failure with mildly reduced/preserved ejection fraction. CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; RR, rate ratio.

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Preserved Ejection Fraction Heart Failure Diabetes Cardiomyopathy 40

Science Daily - Heart Disease

MARCH 26, 2025

Compared with those who spent most of their time in a single room, people with heart failure with preserved ejection fraction (HFpEF) who were able to travel outside of their home without assistance were significantly less likely to be hospitalized or die within a year, according to a new study.

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Heart Failure Preserved Ejection Fraction Outcomes Hospital 65

Circulation

NOVEMBER 11, 2024

Background:SGLT2 inhibitors have demonstrated efficacy in reducing cardiovascular death and hospitalization and are recommended as first-line therapy for hear failure (HF) in adults due to acquired heart diseases. We excluded articles related to acute decompensated HF and HF with preserved ejection fraction.

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Congenital Heart Disease Congenital Heart Disease Preserved Ejection Fraction 40

DAIC

JUNE 26, 2024

Getty Images milla1cf Wed, 06/26/2024 - 18:59 June 26, 2024 — Semaglutide , a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options.

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Preserved Ejection Fraction Obesity BMI Heart Failure 105

Cardiometabolic Health Congress

JULY 25, 2023

There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heart failure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] Is the obesity paradox a real phenomenon?

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Obesity BMI Heart Failure Cardiovascular Disease 52

DAIC

APRIL 9, 2024

HCM is the most common genetic heart disease worldwide and is estimated to affect 1 in 500 people. It causes the heart muscle to become stiff and thick, making it harder for the heart to pump blood properly and increasing the risk of sudden cardiac death. These data strongly support moving on to phase 3 development.”

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Cardiomyopathy Quality of Life Chest Pain Preserved Ejection Fraction 52

Journal of the American Heart Association

MARCH 13, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundSparce data suggest higher mortality in heart failure (HF) with left ventricular ejection fraction (EF) &gt;65% to 70%. We characterized EF distribution, characteristics, and outcomes in patients with HF and EF 50%.Methods

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Preserved Ejection Fraction Heart Failure Peripheral Arterial Disease Cardiomyopathy 70

Science Daily - Heart Disease

APRIL 15, 2025

An international team of researchers has discovered a natural mechanism that protects the heart from heart failure with preserved ejection fraction (HFpEF), a serious condition in need of effective treatment. Importantly, restoring the mechanism prevents the progression of the condition.

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Preserved Ejection Fraction Heart Failure Research 68