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Researchers show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heartattack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.
In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions for causing a stroke or heartattack.
University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heartattacks, strokes, and coronary artery disease.
Researchers have developed a new catheter-based device that combines two powerful optical techniques to image the dangerous plaques that can build up inside the arteries that supply blood to the heart.
Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heartattack.
Exercise prevents and reverses cardiovascular disease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Does this greater plaque presence put athletes at a greater risk of CVD events? Or are the more stable calcified plaques an afterthought?
Researchers at Case Western Reserve University have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heartattack.
You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. All of these parameters are important and need to be considered when evaluating plaque regression. REVERSAL Investigators.
Vascular plaque. It starts with inflammation. Perhaps your blood pressure has been a little too high for a little too long, putting strain on your blood vessels.
Investigators who previously found that a daily statin pill helps prevent heartattacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels. The research led by a team from Mass General Brigham is published in JAMA Cardiology.
fold higher risk for major adverse cardiac events (MACE) Caristo's AI-Risk model, CaRi-Heart Risk Score, outperformed other scores in routine clinical use for prediction of cardiac mortality, and when presented to clinicians, resulted in changes of management decision in 45% of the patients. "The fold higher risk for cardiac mortality and 5.5-fold
In a major study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques, which are formed by the build-up of fatty and cholesterol deposits, constitute a major cause of heartattacks.
The study focused on patients who underwent PCI for acute coronary syndromes (ACS)—life-threatening conditions which include heartattacks and chest pain caused by decreased blood flow to the heart—with stents containing drugs to prevent further plaque buildup.
High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heartattacks and strokes. An estimated 1 in 5 U.S.
PCI is commonly used to open blocked arteries to treat significant myocardial ischemia , which occurs when the heart muscle does not get enough oxygenated blood. The stent is left in place, where it props the artery open to allow blood to flow freely; medications eluted by the stent can also help to prevent further plaque buildup.
MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEARTATTACKS, STROKES AND CORONARY ARTERY DISEASE. When they break loose, they can be deadly, triggering strokes and heartattacks.
mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J. mg improved several measures of plaque volume changes over a period of 12 months in patients with stable coronary artery disease, Dr. Budoff continued.
The CaRi-Plaque technology supports non-invasive analysis of coronary anatomy and pathology from routine coronary computed tomography angiography (CCTA) scans to determine the presence, extent and severity of coronary plaques and luminal stenosis (narrowing of arteries). But with AI, we can change that.
People with type 2 diabetes have a higher risk of suffering a stroke, a heartattack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are.
Cleerly is dedicated to creating a new standard of care for heart disease by using FDA-cleared solutions powered by artificial intelligence. We are very excited to see our purpose-driven mission come to life, making advanced cardiac care accessible to more patients and working towards our goal of eliminating heartattacks.” “We
Researchers found an artificial intelligence (AI) system to help guide treatment decisions for stroke patients led to improved stroke care quality and fewer recurrent strokes, heartattacks and vascular death among stroke survivors three months after a stroke. and Global Data From the American Heart Association.
A landmark NEJM study revealed that many patients with carotid artery disease might have microplastics and nanoplastics (MNPs) embedded in their carotid plaque, and those patients have a massive 4.5-fold fold greater risk of heartattack, stroke, or death within three years. in patients without MNPs in their plaque.
milla1cf Sat, 04/06/2024 - 18:32 April 6, 2024 — The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heartattack or stroke within three months of a prior heartattack, according to research presented at the American College of Cardiology ’s Annual Scientific Session.
The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heartattack or stroke within three months of a prior heartattack, according to research presented at ACC.24, 24, the American College of Cardiology Annual Annual Scientific Session.
Kenneth Chan, MBBS, Academic Clinical Research Fellow in the Division of Cardiovascular Medicine at Oxford University Hospitals (UK) will receive the 2024 SCCT Clinical Trials and Registries Award (CTRA) at the opening session of the Society’s 19th Annual Scientific Meeting (SCCT2024) on Friday, July 19 in Washington, DC.
mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J. mg improved several measures of plaque volume changes over a period of 12 months in patients with stable coronary artery disease, Dr. Budoff continued.
Common Heart Diseases with Genetic Links Coronary Artery Disease (CAD): CAD occurs when the arteries supplying blood to the heart become narrowed or blocked. Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. How Do Genetic Factors Work?
They will also selectively support clinical research involving the CaRi-Heart technology for coronary inflammation diagnostics and LODOCO 0.5 Caristo shares Agepha Pharma’s passion for fighting coronary inflammation, which is one of the primary drivers of heartattack risks,” said Frank Cheng , CEO of Caristo Diagnostics.
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heartattack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4
Arteries generally narrow and occlude for one of two reasons: The progressive accumulation of plaque. A plaque ruptures, and a clot forms in the artery, thereby occluding it. The second reason is commonly referred to as a ‘HeartAttack’ or acute coronary syndrome. Prevent you from having a future heartattack.
CT coronary angiography, in addition to a CT CAC, is arguably the best test for estimating whether someone has evidence of coronary artery disease and what that means for their near-term risk of a heartattack. Mixed Plaque - A combination of both calcified and NON-calcified plaque. More often than you would think!
Morteza Naghavi, founder and president of HeartLung Technologies, and founder of nonprofit SHAPE (Society for HeartAttack Prevention and Eradication). said Dr. Anthony Reeves, professor of electrical engineering and computer vision at Cornell University who participated in AutoChamber research studies and scientific publications. “AI-enabled
Subscribe now Stenting stable coronary artery disease has not been convincingly proven to reduce the risk of future heartattacks or death 1. The cause of angina usually involves inadequate blood flow reaching the heart muscle because of significant narrowing of the artery due to plaque buildup. All is fixed.
(Session 511) Practice-Change Late-breakers ACC24 will offer practice-changing science that will be offered throughout the meeting, including late breaking-clinical trials as well as featured clinical research. EMPACT-MI—takes a look at empagliflozin applied to MIs instead of heart failure.
The history of diagnostic testing for coronary disease shows that we are better and better at identifying disease, but simply identifying coronary plaque isn’t the home run people think because of how ubiquitous the development of coronary plaque is in humans.
Researchers said the study underscores the importance of recognizing and addressing early warning signs of heart disease risk in women as they lose the protective effects of estrogen after menopause. A higher CAC score indicates a higher risk of a heartattack or other cardiac events.
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