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Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heartattack, and more, making it the focus of many heart health campaigns.
Researchers show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heartattack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.
In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions for causing a stroke or heartattack.
University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heartattacks, strokes, and coronary artery disease.
MILLER, PHD, LED THE DEVELOPMENT OF A NEW "ATHEROSCLEROSIS ATLAS" THAT DETAILS, AT THE LEVEL OF INDIVIDUAL CELLS, CRITICAL PROCESSES RESPONSIBLE FOR FORMING THE HARMFUL PLAQUE BUILDUP THAT CAUSES HEARTATTACKS, STROKES AND CORONARY ARTERY DISEASE.
“Cholesterol does not cause heart disease.“ “ “Statins do not prevent heartattacks.” In the middle of this hurricane of noise are people who just want to know what to do so they don’t have a heartattack at a young age. “Statins do not prevent heartattacks.”
milla1cf Sat, 04/06/2024 - 18:32 April 6, 2024 — The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heartattack or stroke within three months of a prior heartattack, according to research presented at the American College of Cardiology ’s Annual Scientific Session.
For every 20mmHg increase in systolic (Top Number) blood pressure, the risk of dying from a heartattack or stroke doubles 3. A cardiac CT is a low-dose CT scan of your heart that assesses whether or not you have plaque in your coronary arteries and, if so, how much. Blood pressure is easy to check.
The CaRi-Plaque technology supports non-invasive analysis of coronary anatomy and pathology from routine coronary computed tomography angiography (CCTA) scans to determine the presence, extent and severity of coronary plaques and luminal stenosis (narrowing of arteries). But with AI, we can change that.
The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heartattack or stroke within three months of a prior heartattack, according to research presented at ACC.24, 24, the American College of Cardiology Annual Annual Scientific Session.
Doctors may be able to leverage the new insights to identify patients at greatest risk of having atherosclerotic plaques break free and cause heartattacks or strokes.
Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heartattack.
Researchers have developed a new catheter-based device that combines two powerful optical techniques to image the dangerous plaques that can build up inside the arteries that supply blood to the heart.
Investigators who previously found that a daily statin pill helps prevent heartattacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels.
In some cases, these levels -- specifically high low-density lipoprotein (LDL) cholesterol, often thought of as 'bad cholesterol,' -- were linked to plaque buildup and cardiovascular events, such as heartattack and stroke.
People with type 2 diabetes have a higher risk of suffering a stroke, a heartattack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are.
Researchers at Case Western Reserve University have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heartattack.
A landmark NEJM study revealed that many patients with carotid artery disease might have microplastics and nanoplastics (MNPs) embedded in their carotid plaque, and those patients have a massive 4.5-fold fold greater risk of heartattack, stroke, or death within three years. in patients without MNPs in their plaque.
This registry will aim to provide world-wide physicians the most accurate information on coronary plaque to improve cardiovascular risk prediction and support the selection of patient-specific treatment,” said Dr. De Cecco. The ultimate goal is to positively impact cardiovascular health globally with a reduction in cardiovascular events."
Image courtesy: Getty Images christine.book Thu, 02/08/2024 - 15:53 February 8, 2024 — The latest late-breaking science from the second day of the American Stroke Association ’s International Stroke Conference , ISC 2024 , shed light on the use of artificial intelligence ( AI ) to help guide treatment decisions for stroke patients.
Investigators who previously found that a daily statin pill helps prevent heartattacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels.
However, for people with risks for heart disease, these warning signals can have a negative consequence: they can increase the size of plaque in arteries, making them narrow, and trigger inflammatory events that can cause plaque to rupture. This can set the stage for a heartattack or stroke.
fold higher risk for major adverse cardiac events (MACE) Caristo's AI-Risk model, CaRi-Heart Risk Score, outperformed other scores in routine clinical use for prediction of cardiac mortality, and when presented to clinicians, resulted in changes of management decision in 45% of the patients. "The fold higher risk for cardiac mortality and 5.5-fold
15, 2024 – Elucid has announced that four of the seven Medicare Administrative Contractors (MACs) will extend coverage for AI-enabled quantitative coronary plaque analysis, including its FDA-cleared PlaqueIQ image analysis software, beginning Nov. tim.hodson Tue, 10/15/2024 - 12:12 Oct.
Artery Damage : Hypertension damages the inner lining of your arteries, making them less elastic and more prone to plaque buildup. This condition, called atherosclerosis, narrows the arteries, restricting blood flow and increasing the risk of heartattacks and strokes.
While it is true that the older you are, the higher the risk of a heartattack, the process of plaque buildup starts early in life. Over half of all ‘healthy’ heart arteries examined before being used for a heart transplant were shown to have evidence of early plaque buildup. 33 years of age.
The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heartattacks. miRNA expression profiles of serum-derived EVs were obtained by small RNA sequencing and in plaque material simultaneously acquired from patients.
The study focused on patients who underwent PCI for acute coronary syndromes (ACS)—life-threatening conditions which include heartattacks and chest pain caused by decreased blood flow to the heart—with stents containing drugs to prevent further plaque buildup.
This refers to all the steps necessary to reduce the odds of a subsequent event, such as a second heartattack or stroke. So, let’s cover seven things that reduce the risk of a subsequent heartattack. This is a program that starts the day of your heartattack. Cardiac Rehabilitation.
On the basis of these findings we told her that she had suffered a heartattack. She asked me why I felt she had had a heartattack and I explained to her that she had had chest pains and the blood test indicating damage to the heart was elevated and that was all we needed to say that she had had a heartattack.
Increased Heart Rate and Blood Pressure: Nicotine stimulates the adrenal glands to release adrenaline, which increases heart rate and blood pressure. Over time, this constant strain can damage the heart and arteries.
Everyone starts with no plaque in the coronary arteries, but over a long enough time frame, everyone develops plaque in their coronary arteries. By age 80, almost everyone will have evidence of advanced plaque in their coronary arteries, as defined by a cardiac CT 1. Plaque accumulation happens in stages. You got it.
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heartattack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4
In a major study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques, which are formed by the build-up of fatty and cholesterol deposits, constitute a major cause of heartattacks.
“By adding AutoChamber AI to thoracic CT scans including coronary artery calcium (CAC) and coronary CT angiography (CCTA), doctors not only can evaluate coronary disease but also the risk of heart failure, atrial fibrillation and stroke which are not reported today.
Common Heart Diseases with Genetic Links Coronary Artery Disease (CAD): CAD occurs when the arteries supplying blood to the heart become narrowed or blocked. Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. How Do Genetic Factors Work?
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heartattack, stroke and death for people with Peripheral Artery Disease (PAD).
tim.hodson Tue, 10/01/2024 - 10:50 PHOTO CAPTION: The Elucid PlaqueIQ user interface is a fully interactive visualization of the patient’s coronary anatomy, showing specific plaque type and amount across various views to inform physician assessment of risk and patient-specific treatment pathway.
While this response is adaptive in the short term, chronic stress keeps your blood pressure elevated for extended periods, increasing your risk of hypertension (high blood pressure) and its associated complications, such as heart disease and stroke.
CT coronary angiography, in addition to a CT CAC, is arguably the best test for estimating whether someone has evidence of coronary artery disease and what that means for their near-term risk of a heartattack. Mixed Plaque - A combination of both calcified and NON-calcified plaque. More often than you would think!
High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heartattacks and strokes. An estimated 1 in 5 U.S.
It encompasses several factors, including the strength and efficiency of the heart, the flexibility and health of the blood vessels, and the ability of the cardiovascular system to deliver oxygen and nutrients to the body’s tissues. Moreover, a healthy heart contributes to improved overall fitness, endurance, and quality of life.
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