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Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidneydisease with additional cardiovascular risk factors, can significantly reduce heartattack and stroke among these patients, according to results from an international clinical trial led by a Mount Sinai researcher.
(MedPage Today) -- The dual SGLT1/2 inhibitor sotagliflozin (Inpefa) reduced the risk for myocardial infarction (MI) and stroke in high-risk patients with type 2 diabetes (T2D), chronic kidneydisease (CKD), and cardiovascular risk factors, a prespecified.
However, researchers said the drug may be helpful in reducing heart failure risks, including hospitalization, following a heartattack. The study enrolled 6,522 people treated for acute myocardial infarction at 451 centers in 22 countries. About 32% had Type 2 diabetes.
While composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce heart failure risks after a heartattack, according to results from the EMPACT-MI trial presented on day one of the American College of Cardiology Scientific Sessions, ACC.24,
Secondary hypertension : This type results from an underlying condition such as kidneydisease, hormonal disorders, or the use of certain medications. The Link Between High Blood Pressure and Heart Health Your heart and blood vessels form a complex network that ensures oxygen and nutrients reach every part of your body.
This condition occurs when the blood vessels that supply blood to the heart become blocked or narrowed by plaque buildup. As a result, the heart doesnt receive enough oxygen-rich blood, which can lead to chest pain, shortness of breath, or even a heartattack.
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
High blood pressure, or hypertension , is a leading cause of heartattacks, strokes and death. It occurs when the heart has to work harder to push blood through the blood vessels, increasing pressure inside the vessels. Centers for Disease Control and Prevention (CDC) estimates that nearly half of U.S.
And if it’s not, your risk of: Heartdisease. Heartattack. Kidneydisease. For every 20 mmHg increase in systolic blood pressure above normal, the risk of dying from a heartattack or stroke doubles 3. But odds are, your blood pressure should be in this range. Dementia An early death.
This leaves a gap in the care of these patients and increases their risk for heartattack, stroke and heart failure progression. HTN accelerates the progression of atherosclerosis and leads to increased risk of major cardiac events like heartattack, heart failure, kidneydisease and other end organ damage.
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heartattack, stroke and death for people with Peripheral Artery Disease (PAD).
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