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(MedPage Today) -- Healthier lifestyle behaviors in midlife were linked with better outcomes in people with geneticpredisposition for age-related brain diseases, longitudinal data from the U.K. Biobank showed. Over about 12 years of follow-up.
Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and geneticpredispositions. Familial Hypercholesterolemia (FH): FH is a genetic disorder resulting in high LDL cholesterol levels from an early age, significantly raising the risk of heart attacks.
Stroke, Ahead of Print. The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming to reduce the growing impact of cerebrovascular disease.
about 12 infants in 1,000 births have a congenital heart defect, according to the Associations 2025 Heart Disease and Stroke Statistics. Our research highlights the importance of maternal factors and genetic traits and understanding how they may be connected, said study author June Huh, M.D., In the U.S.,
Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.
Stroke, Ahead of Print. Cervical artery dissection is an important cause of stroke, particularly in young adults. Cervical artery dissection occurs as a result of the interplay among risk factors, minor trauma, anatomic and congenital abnormalities, and geneticpredisposition.
Studies show that repeated binge drinking can contribute to spikes in blood pressure, increasing the likelihood of stroke, heart attack, and heart failure. The Role of Genetics and Individual Risk Factors Individual risk factors play a crucial role in how alcohol affects the heart.
Black Americans are less prone to develop AF than White Americans, but they display a higher burden of modifiable risk factors for cardiovascular disease and higher rates of ischemic stroke.
Stroke, Ahead of Print. Subarachnoid hemorrhage is a critical neurological condition accounting for about 5% of all strokes, and survivors experience long-term cognitive deterioration and increased risk of dementia. Management techniques reviewed include long-term cognitive health, such as endovascular coiling and surgical clipping.
Results Our study identified a geneticpredisposition associated with an additional 3.6 Sensitivity analyses, including heterogeneity and pleiotropy tests, were conducted to ensure the robustness of our findings. years of education, which significantly reduced the risk of various CVDs.
Stroke, Volume 56, Issue Suppl_1 , Page ATP46-ATP46, February 1, 2025. Background:Modifiable lifestyle factors such as diet and geneticpredisposition influence cognitive aging. Genetics may interact with dietary patterns to further impact cognitive function through the gut-brain axis.
Stroke, Volume 55, Issue Suppl_1 , Page ATP248-ATP248, February 1, 2024. Background:Diabetes is a highly heritable stroke risk factor with numerous known genetic risk variants. However, the role of these genetic risk variants in the development of cerebrovascular disease in Native Hawaiians remains unknown. 2.05; p=0.04).Conclusions:Among
Stroke, Volume 55, Issue Suppl_1 , Page A8-A8, February 1, 2024. Background:Common genetic variation explains up to 40% of blood pressure variation. Despite this compelling physiological impact, the role of common genetic variation in blood pressure treatment and their sequelae remains understudied. for both analyses).Conclusions:Among
Stroke, Volume 56, Issue Suppl_1 , Page ATMP101-ATMP101, February 1, 2025. Background:Clinical and geneticpredispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear.
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