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Study unveils impact of cardiovascular risk factors on genetic predisposition to heart disease

Medical Xpress - Cardiology

Heersink School of Medicine have unveiled critical insights into the influence of high-proportion spliced-in titin truncating variants, or hiPSI TTNtv, on cardiovascular disease risk. Physician-scientists from the University of Alabama at Birmingham Marnix E.

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Physiology Friday #245: Fitness Protects against Neurodegenerative Diseases—Even in Those at the Greatest Risk

Physiologically Speaking

Insulin resistance and impaired glucose metabolism are risk factors for Alzheimer's disease, hence why the disease is sometimes referred to as ‘type 3 diabetes.’ One’s risk of certain diseases (i.e., And the good news is that fitness is a modifiable risk factor.

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Thrombotic Thrombocytopenic Purpura: A Missed Cause in Stroke Prevention Guidelines

Stroke Journal

These guidelines emphasize modifiable risk factors and population-specific considerations, covering a range of cardiovascular conditions, including hypertension, diabetes, atherosclerotic disease, and genetic predispositions to stroke.

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Atrial Fibrillation in Black American Patients: A Review of Genetics, Risk Factors, and Outcomes

HeartRhythm

Black Americans are less prone to develop AF than White Americans, but they display a higher burden of modifiable risk factors for cardiovascular disease and higher rates of ischemic stroke.

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Clinical and Genetic Risk Factors Predict Atrial Fibrillation on the Basis of Hypertrophic Cardiomyopathy

Journal of the American Heart Association

BackgroundClinical and genetic predispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear. Journal of the American Heart Association, Ahead of Print.

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PO-03-084 GENETIC PREDISPOSITION TO ATRIAL FIBRILLATION INCREASES ISCHEMIC STROKE RISK AMONG INDIVIDUALS WITH ATRIAL FIBRILLATION

HeartRhythm

Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.

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Treatment and Outcomes of Cervical Artery Dissection in Adults: A Scientific Statement From the American Heart Association

Stroke Journal

Cervical artery dissection occurs as a result of the interplay among risk factors, minor trauma, anatomic and congenital abnormalities, and genetic predisposition. The writing group chair and vice chair compiled the manuscript and obtained writing group members’ approval.