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Study unveils impact of cardiovascular risk factors on genetic predisposition to heart disease

Medical Xpress - Cardiology

Heersink School of Medicine have unveiled critical insights into the influence of high-proportion spliced-in titin truncating variants, or hiPSI TTNtv, on cardiovascular disease risk. Physician-scientists from the University of Alabama at Birmingham Marnix E.

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PO-03-084 GENETIC PREDISPOSITION TO ATRIAL FIBRILLATION INCREASES ISCHEMIC STROKE RISK AMONG INDIVIDUALS WITH ATRIAL FIBRILLATION

HeartRhythm

Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.

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Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation

Heart BMJ

Background The relationship between combined genetic predisposition and lifestyle and the risk of incident atrial fibrillation (AF) is unclear. Therefore, we aimed to assess a possible interaction between lifestyle and genetics on AF risk.

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Neurodevelopmental Outcomes for Individuals With Congenital Heart Disease: Updates in Neuroprotection, Risk-Stratification, Evaluation, and Management: A Scientific Statement From the American Heart Association

Circulation

It also includes an updated algorithm for referral, evaluation, and management of individuals at high risk. It also includes an updated algorithm for referral, evaluation, and management of individuals at high risk. Critical next steps must include efforts to prevent and mitigate developmental delays and disorders.

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Treatment and Outcomes of Cervical Artery Dissection in Adults: A Scientific Statement From the American Heart Association

Stroke Journal

Cervical artery dissection occurs as a result of the interplay among risk factors, minor trauma, anatomic and congenital abnormalities, and genetic predisposition. The writing group chair and vice chair compiled the manuscript and obtained writing group members’ approval.

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Sweetened Beverages, Genetic Susceptibility, and Incident Atrial Fibrillation: A Prospective Cohort Study

Circulation: Arrhythmia and Electrophysiology

The highest HRs (95% CIs) of AF were observed for participants at high genetic risk who consumed >2 L/wk of ASB (HR, 3.51 [95% CI, 2.94–4.19]), 4.19]), and the lowest HR were observed for those at low genetic risk who consumed ≤1 L/wk of PJ (HR, 0.77 [95% CI, 0.65–0.92]).

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Debunking Myths About Cardiac Health and Heart Diseases

Wellnest

While it is true that the risk of cardiovascular disease increases with age, it can strike people of all ages, including young adults and even children. Unhealthy lifestyle habits, genetics, obesity, and other risk factors can contribute to cardiac disease at any stage of life. Myth #3: Heart diseases only affect men.