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tim.hodson Mon, 03/17/2025 - 14:56 March 17, 2025 Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Associations flagship journal Circulation. Researchers analyzed health information about more than 3.5 In the U.S.,
BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the geneticpredisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.
dementia and Alzheimer’s) can be assessed using polygenic risk scores, which aggregate the effects of numerous genetic variants to estimate geneticpredisposition. Offsetting a high geneticpredisposition might require a bit more focus and attention to optimizing your cardiorespiratory fitness. Moderate: 24.1–31.1
Researchers have shown for the first time that geneticpredisposition to sedentary behavior is associated with a higher risk of developing the most common cardiovascular diseases. A high geneticpredisposition to sedentary behavior can increase the risk of cardiovascular diseases by up to 20%.
The researchers investigated how various types of incidental and intermittent activity influence cardiovascular event risk, particularly when combined with varying levels of sedentary time. The inevitable conclusion for our training is that we need both low- and high-intensity training to truly reach our peak potential.
Over the past decade, new research has advanced scientific knowledge of neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and neuroprotective strategies for individuals with congenital heart disease. Circulation, Ahead of Print.
Geneticpredispositions have been associated with post-subarachnoid hemorrhage cognitive outcomes and emphasize a role for personalized care strategies. The major processes involved in such decline include early brain injury, delayed cerebral ischemia, neuroinflammation, superficial siderosis, and hydrocephalus.
Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and geneticpredispositions. While you can’t change your genetic code, having a family history of heart disease does not mean your fate is sealed.
Some research suggests that moderate drinkers may have a lower risk of heart disease compared to those who abstain or engage in heavy drinking. However, the effects of alcohol vary widely depending on individual health, lifestyle factors, and genetics. Over time, this can contribute to heart failure and other serious complications.
Background:Diabetes is a highly heritable stroke risk factor with numerous known genetic risk variants. However, the role of these genetic risk variants in the development of cerebrovascular disease in Native Hawaiians remains unknown. Geneticpredisposition to diabetes was associated with a 23% higher risk of diabetes (OR 1.23, CI 1.01-1.51;
While lifestyle factors such as diet, exercise and smoking play a significant role in the development of heart disease, genetics also contribute substantially. GeneticPredispositionGeneticpredisposition to heart disease is a reality for many individuals.
We hypothesize that a higher polygenic predisposition to hypertension leads to a poorer response to blood pressure (BP) treatment and higher stroke risk in a primary prevention setting.Methods:We conducted a 2-stage genetic association study using data from the All of Us Research Program (discovery stage) and UK Biobank (replication stage).
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