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Results Our study identified a geneticpredisposition associated with an additional 3.6 years of education, which significantly reduced the risk of various CVDs. However, no significant evidence revealed a causal relationship between education and pulmonary embolism.
The Need for Personalization in Cardiology Cardiovascular health is inherently complex, with conditions ranging from hypertension to heartfailure requiring specific treatment plans. Given the vast array of patient profiles and varying conditions, more than a one-size-fits-all approach is needed.
Although mediation analysis demonstrated that the association between PGSMDand CVDs in females was partly mediated by baseline body mass index, hypercholesterolemia, hypertension, and smoking, these risk factors did not explain the higher risk compared with males.
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Genetic predisposition 
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