HCPLive

FEBRUARY 9, 2024

Multivariable analyses found genetic predispositions to overall rheumatoid arthritis with decreased sleep duration, as well as a significant genetic association between seropositive rheumatoid arthritis and insomnia symptoms.

Genetic predisposition 105

Genetic predisposition 105

HCPLive

FEBRUARY 25, 2025

These data point to increasing omega-3 consumption as a potential preventive strategy against atopic dermatitis.

Genetic predisposition 63

Genetic predisposition 63

Medical Xpress - Cardiology

AUGUST 19, 2024

An unhealthy lifestyle, diseases or injuries, genetic predisposition, and increased coagulation tendency can promote the formation of thrombi in blood vessels. These clots obstruct the flow of blood to vital organs, which may lead to life-threatening infarction.

Genetic predisposition 95

Genetic predisposition Thrombosis 95

Stroke Journal

MARCH 7, 2025

These guidelines emphasize modifiable risk factors and population-specific considerations, covering a range of cardiovascular conditions, including hypertension, diabetes, atherosclerotic disease, and genetic predispositions to stroke.

Genetic predisposition 40

Genetic predisposition Stroke Strokes Cerebrovascular Disease 40

Cardiovascular Diabetology

DECEMBER 20, 2024

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

Genetic predisposition 64

Genetic predisposition Cardiovascular Disease Diabetes Hypertension 64

Medical Xpress - Cardiology

NOVEMBER 18, 2024

Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as coronary artery disease (CAD).

Genetic Markers 64

Genetic Markers Genetic predisposition Heart Disease Coronary Artery Disease 64

American College of Cardiology

MAY 6, 2024

What is the prevalence, what is the genetic predisposition, and what are the clinical consequences of reduced left (LVEF) and/or right ventricular ejection fraction (RVEF) among endurance athletes?

Genetic predisposition 58

Genetic predisposition Article 58

Circulation

MARCH 13, 2025

In many cases, direct-to-consumer genetic testing advertises information that could inform ones risk of heritable disease, including insight into having a genetic predisposition to cardiovascular disease or data about gene-drug interactions that could affect response to cardiovascular medications.

Cardiovascular Disease 78

Cardiovascular Disease Genetic predisposition Laboratory Circulation 78

HCPLive

DECEMBER 4, 2024

Panelists discuss how elevated LDL-C levels significantly contribute to ASCVD development through both modifiable lifestyle factors and genetic predisposition, making it a critical target for cardiovascular disease prevention.

Genetic predisposition 52

Genetic predisposition Cardiovascular Disease 52

DAIC

MARCH 17, 2025

Potential factors include the mothers genetic predisposition or a mutation known to contribute to cancer and congenital heart defect risks in newborns. Researchers have yet to determine why having a baby with a congenital heart defect is associated with a higher risk for cancer in mothers.

Cancer 52

Cancer Research Congenital Genetic predisposition 52

Journal of the American Heart Association

MARCH 13, 2025

Results from the inverse varianceweighted model indicated that genetic predispositions for human leukocyte antigentype DR (HLA DR) on CD33dim HLA DR+ CD11b+ (odds ratio, 0.967 [95% CI, 0.9390.996];P=0.028) may be associated with a reduced risk of HF.

Genetic predisposition 45

Genetic predisposition Heart Failure 45

American College of Cardiology

NOVEMBER 11, 2024

What is the causality between genetic predisposition to gestational diabetes mellitus (GDM) and the risk of cardiovascular disease (CVD)?

Genetic predisposition 47

Genetic predisposition Diabetes Cardiovascular Disease Article 47

HeartRhythm

APRIL 30, 2024

Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.

Atrial Fibrillation 40

Atrial Fibrillation Genetic predisposition Stroke Strokes 40

MIBHS

MARCH 15, 2025

The Role of Genetics and Individual Risk Factors Individual risk factors play a crucial role in how alcohol affects the heart. Some people may have a genetic predisposition to high blood pressure, while others may metabolize alcohol differently, making them more susceptible to cardiovascular issues.

Blood Pressure 52

Blood Pressure Heart Rhythm Blood Clot Heart Disease 52

Stroke Journal

FEBRUARY 1, 2024

Cervical artery dissection occurs as a result of the interplay among risk factors, minor trauma, anatomic and congenital abnormalities, and genetic predisposition. The writing group chair and vice chair compiled the manuscript and obtained writing group members’ approval.

Genetic predisposition 75

Genetic predisposition Outcomes Thrombolysis Congenital 75

Circulation

FEBRUARY 22, 2024

It also includes an updated algorithm for referral, evaluation, and management of individuals at high risk.

Congenital Heart Disease 75

Congenital Heart Disease Congenital Heart Disease Genetic predisposition 75

HeartRhythm

APRIL 30, 2024

Genetic predisposition to ventricular scarring is associated with heart failure and ventricular arrhythmia. Although many pathogenic variants have been shown to predispose patients to poor outcomes, the impact of many VUS remains uncharacterized.

Genetic predisposition 40

Genetic predisposition Heart Failure Arrhythmia Cardiomyopathy 40

HeartRhythm

APRIL 30, 2024

Genetic predisposition to septal scarring can result in ventricular arrhythmia and poorer ablation outcomes. There is a need to better define these genetic variants to understand clinical implications. Many commonly occurring variants continue to be described as variants of uncertain significance (VUS).

Genetic predisposition 40

Genetic predisposition Ablation Arrhythmia Outcomes 40

Physiologically Speaking

DECEMBER 2, 2024

This study examined the relationship between cardiorespiratory fitness and the risk of developing neurodegenerative diseases, such as dementia and Alzheimer’s, particularly in individuals with a high genetic predisposition.

Physiology 59

Physiology Exercise Dementia Genetic predisposition 59

Frontiers in Cardiovascular Medicine

JUNE 25, 2024

Factors causing illness include genetic predisposition, aging, stress, chronic inflammation, environmental factors, declining autophagy, and endocrine abnormalities including insufficient vitamin D levels. Among the leading causes of natural death are cardiovascular diseases, cancer, and respiratory diseases.

Cardiovascular Disease 52

Cardiovascular Disease Genetic predisposition Pharmacology Cancer 52

Frontiers in Cardiovascular Medicine

APRIL 29, 2024

mediation effect.DiscussionThe results underscore the genetic predisposition of ICP to elevate CVD risk and the critical mediating role of lipid levels, emphasizing the need for vigilant lipid monitoring and early intervention in individuals with ICP.

Cardiovascular Disease 52

Cardiovascular Disease Genetic predisposition Coronary Artery Disease Hypertension 52

AMS Cardiology

OCTOBER 11, 2023

While lifestyle factors such as diet, exercise and smoking play a significant role in the development of heart disease, genetics also contribute substantially. Genetic Predisposition Genetic predisposition to heart disease is a reality for many individuals.

Heart Disease 52

Heart Disease Genetic predisposition Diet Genetic Markers 52

Stroke Journal

MARCH 4, 2025

Genetic predispositions have been associated with post-subarachnoid hemorrhage cognitive outcomes and emphasize a role for personalized care strategies. The major processes involved in such decline include early brain injury, delayed cerebral ischemia, neuroinflammation, superficial siderosis, and hydrocephalus.

Hemorrhage 40

Hemorrhage Genetic predisposition Genetic Markers Quality of Life 40

HeartRhythm

NOVEMBER 5, 2024

Data pertaining to the American Heart Association Life’s Simple 7 (LS7) health metrics show that Black Americans have suboptimal LS7 scores compared to White Americans on average despite lower genetic predisposition to AF.

Atrial Fibrillation 40

Atrial Fibrillation Risk Factors Genetic predisposition Outcomes 40

Heart BMJ

APRIL 15, 2024

Background The relationship between combined genetic predisposition and lifestyle and the risk of incident atrial fibrillation (AF) is unclear. Therefore, we aimed to assess a possible interaction between lifestyle and genetics on AF risk.

Atrial Fibrillation 52

Atrial Fibrillation Genetic predisposition Risk Factors Diet 52

Journal of the American Heart Association

MARCH 13, 2025

BackgroundClinical and genetic predispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear. Journal of the American Heart Association, Ahead of Print.

Atrial Fibrillation 45

Atrial Fibrillation Risk Factors Cardiomyopathy Genetic predisposition 45

Frontiers in Cardiovascular Medicine

FEBRUARY 14, 2024

Results Our study identified a genetic predisposition associated with an additional 3.6 Causality was assessed using the inverse-variance weighted (IVW), ME-Egger regression, and weighted median methods. Sensitivity analyses, including heterogeneity and pleiotropy tests, were conducted to ensure the robustness of our findings.

Education 49

Education Cardiovascular Disease Peripheral Arterial Disease Genetic predisposition 49

Dr. Paddy Barrett

APRIL 26, 2024

Yes, there is a genetic predisposition at play. But I am saying that even if you have developed type 2 diabetes, which is a major driver of risk, there is still a huge amount that can be done to reduce future risk. But why wait? For sure. ( I know because I have some of those genes ). They set the odds.

Heart Disease 104

Heart Disease Coronary Artery Disease Diabetes Genetic predisposition 104

Circulation

NOVEMBER 11, 2024

The SRPS is hypothesised to facilitate early detection and inform targeted interventions.Aim:The primary aim is to conceptualise and outline the SRPS, which categorises individuals into risk categories based on a point system reflecting genetic predispositions, clinical symptoms, dietary habits, and response to treatments.

Genetic predisposition 40

Genetic predisposition Lipid disorders Innovation Risk Factors 40

Journal of the American Heart Association

FEBRUARY 26, 2025

Genetic predisposition to long QT syndrome was explored using rare variant analysis.ResultsSeventyfour independent loci were obtained with genomewide significance across the 6 traits (P<5108). Middle Eastern PRSs were developed using clumping and thresholding, and their performance was compared with 26 published PRSs.

Electrocardiogram 45

Electrocardiogram Genetic predisposition Cardiovascular Disease Cardiomyopathy 45

Circulation: Arrhythmia and Electrophysiology

MARCH 5, 2024

The highest HRs (95% CIs) of AF were observed for participants at high genetic risk who consumed >2 L/wk of ASB (HR, 3.51 [95% CI, 2.94–4.19]), 4.19]), and the lowest HR were observed for those at low genetic risk who consumed ≤1 L/wk of PJ (HR, 0.77 [95% CI, 0.65–0.92]).

Atrial Fibrillation 40

Atrial Fibrillation Genetic predisposition Diet Electrophysiology 40

Stroke Journal

JANUARY 30, 2025

Background:Modifiable lifestyle factors such as diet and genetic predisposition influence cognitive aging. Genetics may interact with dietary patterns to further impact cognitive function through the gut-brain axis. Stroke, Volume 56, Issue Suppl_1 , Page ATP46-ATP46, February 1, 2025.

Diet 40

Diet Genetic predisposition Stroke Strokes 40

Wellnest

AUGUST 24, 2023

By adopting a heart-healthy diet, engaging in regular physical activity, managing stress, avoiding smoking, and controlling blood pressure and cholesterol levels, we can mitigate genetic predispositions' impact and reduce our overall risk of cardiovascular disease. Myth #3: Heart diseases only affect men.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol Genetic predisposition 52

GEMMS

SEPTEMBER 27, 2024

Personalized treatment plans consider genetic predispositions, lifestyle, and comorbidities, ensuring that each patient receives the most effective care. The Need for Personalization in Cardiology Cardiovascular health is inherently complex, with conditions ranging from hypertension to heart failure requiring specific treatment plans.

Technology 52

Technology Genetic predisposition Patient Care Education 52

Stroke Journal

FEBRUARY 1, 2024

Background:Diabetes is a highly heritable stroke risk factor with numerous known genetic risk variants. However, the role of these genetic risk variants in the development of cerebrovascular disease in Native Hawaiians remains unknown. Genetic predisposition to diabetes was associated with a 23% higher risk of diabetes (OR 1.23, CI 1.01-1.51;

Genetic predisposition 40

Genetic predisposition Diabetes Stroke Strokes 40

Circulation

DECEMBER 17, 2023

The aim is to assess the prevalence, clinical consequences, and genetic predisposition of reduced EF in athletes.METHODS:Young endurance athletes were recruited from elite training programs and underwent cardiac phenotyping, genetic analyses and clinical events were recorded over a mean of 4.4

Genetic predisposition 77

Genetic predisposition Cardiomyopathy Sudden Cardiac Death Heart Failure 77

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

In recent years, the genetic predisposition for SCAD is also recognized as a predisposing factor. The precipitating factors are also different in women (emotional stress) compared with those in men (physical stress).

SCAD 88

SCAD Genetic predisposition Risk Factors Chest Pain 88