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Affecting 60 million people worldwide 1 , the prevalence of atrial fibrillation (AFib) is expected to increase by 60% by 2050 due to an aging population and rising cardiometabolic riskfactors 2. In addition, the Centers for Disease Control and Prevention (CDC) estimates that more than 12 million Americans will have AFib by 2030 3.
About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke.
Recommendation from UK National Institute for Health and Care Excellence is that people with or at high risk of cardiovascular disease consume at least one portion of oily fish a week. The authors reported that the regular use of fish oil supplements might be a riskfactor for atrial fibrillation among general population.
The 2023 Almanac results derived from the Global Burden of Disease (GBD) and spanning 1990 to 2022, were recently published in the Journal of American College of Cardiology. High systolic blood pressure stands out as a major riskfactor, directly contributing to leading cardiovascular causes of death in LMICs.
Stroke is often due to sudden loss of blood supply to a region of the brain which usually results in paralysis of a part of the body. Stroke could also be due to bleeding into a part of the brain. Strokes and heart disease are linked together in various ways. Stroke can occur after a heart attack as well.
They are more prone to have heart attack and stroke (brain attack), due to disease of their blood vessels. Important riskfactors for diseases of blood vessels are high blood pressure and sugar, high blood fat levels, overweight/obesity, and smoking. Aortic dissection is tear in the inner lining of the aorta.
Primary endpoint of the study was a composite of myocardial infarction, stroke, or death from any cause in those who had micro and nanoplastics in the carotid plaque. Micro- and nanoplastics: A new cardiovascular riskfactor? Inflammatory biomarkers were also estimated. N Engl J Med. 2024 Mar 7;390(10):900-910. PMID: 38446676.
CABANA Trial randomized 2204 patients with AF aged 65 years or more and those below 65 years with one or more riskfactors for stroke for catheter ablation with pulmonary vein ablation or drug therapy with rate or rhythm control. Among the subjects of CABANA trial 35% had NYHA class above II at baseline. doi: 10.1001/jama.2019.0693.
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