Heart BMJ

AUGUST 26, 2024

Background Decreased diffusing capacity of the lungs for carbon monoxide (DLco) is associated with microvascular damage in chronic thromboembolic pulmonary hypertension (CTEPH). The LD group had a shorter 6-minute walking distance (324±91 vs 427±114 m) than the ND group but the mean pulmonary artery pressure (mPAP) was similar (38.9±7.3

Angioplasty 52

Angioplasty Pulmonary Exercise Hypertension 52

Frontiers in Cardiovascular Medicine

MAY 1, 2024

Fatigue and exercise intolerance are early common symptoms in FD patients but the specific causes are still to be defined. In this narrative review, we deal with the contribution of cardiac and pulmonary dysfunctions in determining fatigue and exercise intolerance in FD patients.

Exercise 52

Exercise Pulmonary 52

Circulation

SEPTEMBER 24, 2024

In this scientific statement, we update the scientific basis of the core components of patient assessment, nutritional counseling, weight management and body composition, cardiovascular disease and risk factor management, psychosocial management, aerobic exercise training, strength training, and physical activity counseling.

Cardiac Rehabilitation 78

Cardiac Rehabilitation Pulmonary Health Disparities Cardiovascular Disease 78

Circulation

NOVEMBER 8, 2024

BACKGROUND:Patients with hypertrophic cardiomyopathy without left ventricular outflow tract obstruction commonly experience reduced exercise capacity. Physical training improves exercise capacity in these patients, but whether the underlying effects of exercise are a result of central hemodynamic or peripheral improvement is unclear.

Exercise 49

Exercise Cardiomyopathy Quality of Life Pulmonary 49

Journal of Cardiothoracic Surgery

SEPTEMBER 8, 2024

Some pulmonary tuberculosis patients may require lung resection surgery. Postoperative pulmonary rehabilitation is essential to restore the lung function and maintain quality of life. We aimed to study the pul.

Pulmonary 52

Pulmonary Quality of Life Nursing Exercise 52

Heart BMJ

MARCH 22, 2024

Objective In Fontan circulation, pulmonary arterial hypertension (PAH)-targeted therapies could improve the patients’ exercise capacity. This study aimed to investigate the effects of PAH agents on different exercise parameters in stable Fontan patients by synthesising evidence of randomised controlled trials (RCTs).

Exercise 40

Exercise Circulation Pulmonary Pharmacology 40

DAIC

MARCH 25, 2025

Efficacy of finerenone according to left atrial size in patients with heart failure and mildly reduced or preserved ejection fraction: An analysis of the FINEARTS-HF trial during the session " Finerenone: A Promising Addition to the Armamentarium or Merely an Academic Exercise?"

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Kidney Disease Research 52

American College of Cardiology

FEBRUARY 11, 2025

What is the safety and utility of invasive implanted hemodynamic monitoring (IHM) using the CardioMEMS™ HF System in pediatric patients with heart failure (HF) and pulmonary hypertension (PH)?

Pediatrics 46

Pediatrics Heart Failure Pulmonary Hypertension 46

Circulation: Heart Failure

MARCH 5, 2025

EIH was defined as systolic blood pressure (BP) at peak exercise >210 mm Hg in men or >190 mm Hg in women.RESULTS:In this prospective cohort study, we assessed patients with COA (n=41, age 4314 years, 26 [63%] men) and healthy controls (n=41).

Exercise 40

Exercise Hypertension Outcomes Biomarkers 40

Circulation

NOVEMBER 11, 2024

Background:Very high level, lifelong aerobic exercise results in lower ventricular stiffness and left ventricular wall stress (LVWS) LVWS is an important predictor of future heart failure risk. As shown in the figure, peak LVWS during saline load (top panel: sedentary 3.1 +/- 1.1 Pa, moderate 2.5 +/- 0.7 Pa, active 2.3 +/- 0.5

Exercise 40

Exercise Heart Failure Pulmonary Circulation 40

Journal of the American Heart Association

DECEMBER 29, 2023

The patients underwent invasive cardiac catheterization and simultaneous echocardiography at rest and during exercise. Those with PH had lower TAPSE/PASP and TAS’/PASP at rest and during exercise compared with those without PH. TAPSE/PASP and TAS’/PASP can be useful parameters to detect PH in patients with HFpEF.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pulmonary Heart Failure Hypertension 40

Journal of the American Heart Association

JULY 19, 2024

Journal of the American Heart Association, Ahead of Print.

Exercise 45

Exercise Pulmonary 45

European Journal of Heart Failure

OCTOBER 30, 2023

Haemodynamic curve morphology is displayed for right atrial (RAP), right ventricular (RVP), mean pulmonary artery (PAP), and pulmonary capillary wedge pressure (PAWP). ΔPAWP: difference of PAWP between rest and peak exercise. The primary outcome was the difference (Δ) between resting and exercise PAWP in each modality.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Exercise Pulmonary 40

European Journal of Heart Failure

DECEMBER 28, 2023

Moreover, the definitions of elevated exercise pulmonary artery (PA) and PA wedge pressure (PAWP) for this population have not been described. There was no difference in exercise arterial O 2 saturation (87% [81;92] vs 89% [85;93], p = 0.29), while exercise PA pressure (27 [23;31] vs 16 [14.5;19.5]

Exercise 40

Exercise Physiology Article Pulmonary 40

Circulation

NOVEMBER 11, 2024

Introduction:Inflammation is a key driver in the development of pulmonary arterial hypertension (PAH). The pulmonary vasculature was evaluated histologically. Rats administered fluconazole had augmented RV function with increased percent RV free wall thickness change (D), RV ejection fraction (E) and RV-pulmonary arterial coupling (F).

Pulmonary 40

Pulmonary Hypertension Innovation Exercise 40

European Journal of Heart Failure

DECEMBER 29, 2023

Abstract Aims We aim to clarify the extent to which cardiac and peripheral impairments to oxygen delivery and utilization contribute to exercise intolerance and risk for adverse events, and how this relates to diversity and multiplicity in pathophysiological traits. Hemodynamics and oxygen transport responses were compared. L/min versus 2.8

Preserved Ejection Fraction 40

Preserved Ejection Fraction Exercise Heart Failure Pulmonary 40

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

When it is large and hemodynamically significant, it can cause symptoms such as dyspnea, exercise intolerance, and palpitations. Patients in Group 2 had greater pulmonary artery systolic pressure than those in Group 1 (p-value<0.001). IntroductionSecundum Atrial septal defect (ASD) is the most common type of ASD. Overall, 88.9%

Hospital 52

Hospital Tachycardia Exercise Pulmonary 52

DAIC

JULY 29, 2024

Building on an investment made in 2016, Edwards has exercised its option to acquire Endotronix , a leader in heart failure (HF) management solutions. Last month, Endotronix received FDA approval for Cordella, an implantable pulmonary artery pressure sensor allowing early, targeted therapeutic intervention.

Innovation 105

Innovation Aortic valve Aortic CMS 105

DAIC

APRIL 22, 2024

We found in our last trial, REDUCE LAP-HF II, that HFpEF patients with pacemakers or pulmonary vascular disease didn't benefit from atrial shunting. In our ongoing RESPONDER-HF trial we are excluding those patients and using exercise hemodynamics to qualify and randomize HFpEF patients most likely to respond favorably to shunting." "In

Preserved Ejection Fraction 105

Preserved Ejection Fraction Quality of Life Heart Failure Pacemaker 105

DAIC

MAY 31, 2024

Given the rapid expansion of sports cardiology, cardiovascular care teams must understand contemporary care and practice management strategies for all athletes—from the elite to the exercise enthusiast.

Cardiac Arrest 111

Cardiac Arrest Exercise Thrombosis Diet 111

MIBHS

OCTOBER 31, 2024

Chronic Pulmonary Disease Lung diseases like chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension, which in turn can cause the right side of the heart to enlarge, a condition known as cor pulmonale. Exercise regularly to keep the heart strong and healthy. Avoid excessive alcohol and drug use.

Blood Pressure 52

Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

American College of Cardiology

JULY 29, 2024

The goal of the CAMEO-DAPA trial was to assess whether dapagliflozin, a sodium-glucose cotransporter-2 inhibitor (SGLT2i), affects rest and exercise pulmonary capillary wedge pressure (PCWP) in patients with heart failure with preserved ejection fraction (HFpEF).

Preserved Ejection Fraction 51

Preserved Ejection Fraction Heart Failure Exercise Pulmonary 51

DAIC

MAY 16, 2024

For patients with PAD and Type 1 or Type 2 diabetes, clinicians should coordinate care to address diet, exercise, weight management, medications to control blood sugar, management of other cardiovascular risk factors and routinely check the feet of their patients for foot ulcer prevention.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

DAIC

MAY 2, 2024

a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, today announced the primary endpoint results of the open label roll-in cohort of the CardiAMP Cell Therapy in Chronic Myocardial Ischemia Trial. Getty Images milla1cf Thu, 05/02/2024 - 10:12 May 2, 2024 — BioCardia, Inc. ,

Ischemia 95

Ischemia Angina Heart Failure Outcomes 95

All About Cardiovascular System and Disorders

MARCH 29, 2024

One is ventricular septal defect, second is overriding aorta, third is pulmonary stenosis, usually right ventricular outflow tract stenosis and associated right ventricular hypertrophy. Pulmonary stenosis, which is usually right ventricular outflow tract stenosis. This will almost invariably result in severe pulmonary regurgitation.

Sudden Cardiac Death 52

Sudden Cardiac Death Pulmonary Stenosis Arrhythmia 52

JAMA Cardiology

JULY 23, 2024

The RV is especially sensitive to afterload, and abnormalities in the pulmonary circulation leading to increased RV afterload may play a critical role in driving the exercise intolerance and high risk of hospitalization characteristic of HFpEF.

Preserved Ejection Fraction 41

Preserved Ejection Fraction Heart Failure Pulmonary Exercise 41

DAIC

MARCH 25, 2025

Efficacy of finerenone according to left atrial size in patients with heart failure and mildly reduced or preserved ejection fraction: An analysis of the FINEARTS-HF trial during the session " Finerenone: A Promising Addition to the Armamentarium or Merely an Academic Exercise?"

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Research Academic 52

Circulation: Heart Failure

DECEMBER 18, 2023

mm Hg with exercise (P&lt;0.001). mm Hg with exercise (P&lt;0.001). At peak exercise, RT was responsible for 64% (53%–76%) of end-diastolic pressure, whereas incomplete relaxation and stiffness accounted for the rest. mm Hg in HF with preserved ejection fraction patients and was also exacerbated by exercise.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Exercise Cardiomyopathy Heart Failure 40

European Journal of Heart Failure

DECEMBER 7, 2023

Patients with more severe obesity were more likely to have responder characteristics for atrial shunt therapy (fewer pacemakers and lower exercise pulmonary vascular resistance [PVR]). Pulmonary vascular resistance at rest and exercise decreased with higher BMI.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Obesity Heart Failure BMI 40

European Journal of Heart Failure

DECEMBER 7, 2023

Methods Patients with HFpEF underwent invasive hemodynamic exercise testing, comprehensive imaging including speckle tracking strain echocardiography, and clinical follow-up at Mayo Clinic between 2006 and 2018. There were 94 patients with events over a median follow-up of 2.9 (IQR 2.92, p = 0.01). 2.92, p = 0.01).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Exercise Atrial Fibrillation 40

Physiologically Speaking

JANUARY 3, 2024

However, the cardiocentric view of circulation fails to explain blood flow regulation during exercise and other unique scenarios. While he didn't fully grasp the complete circulatory system, his insights into the pulmonary circulation were notable for the time. A few interesting proposals for how the heart moves blood emerge.

Physiology 69

Physiology Circulation Pulmonary Exercise 69

Physiologically Speaking

FEBRUARY 16, 2024

There’s a long-running debate in exercise physiology about what limits VO2 max. However, after 8 weeks of exercise training, the limitation of VO2 max shifts to oxygen transport. A new study published in the Journal of Physiology 1 investigated the determinants of VO2 max before and after 8 weeks of endurance exercise training.

Physiology 52

Physiology Exercise Pulmonary Circulation 52

Circulation

NOVEMBER 11, 2024

Background:Patients with Fontan palliation have reduced aerobic capacity because of impaired cardiac, pulmonary, and skeletal muscle function. Conclusions:The results of the current study would help calibrate the interpretation of exercise test data in adults with Fontan palliation and improve risk stratification in this population.

Transplant 40

Transplant Outcomes Exercise Cardiovascular Disease 40

European Journal of Heart Failure

OCTOBER 3, 2023

However, data on clinical characteristics, exercise performance and prognosis in HF patients who improved ejection fraction (HFimpEF) are scarce. Methods and results A total of 7948 patients enrolled in the Metabolic Exercise Cardiac Kidney Indexes (MECKI) score database were evaluated (median follow-up of 1490 days).

Heart Failure 40

Heart Failure Exercise Laboratory Transplant 40

Dr. S. Venkatesan MD

APRIL 18, 2024

It is prudent to understand, that even in systolic LV failure; it is the raised LVEDP that causes the symptoms and marks the limits of exercise capacity. This is to create a small regulatory orifice in the IAS ( A complicated term for a small ASD ) to decompress the LA and reduce pulmonary congestive symptoms. JAMA Cardiol.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Pulmonary Congenital Heart Disease VSD 40

DAIC

JULY 25, 2024

During heart failure progression, the heart steadily loses its ability to respond to increased metabolic demand, and mild exercise soon exceeds the heart’s ability to maintain adequate output. mtaschetta-millane Thu, 07/25/2024 - 09:08 July 25, 2024 — BioCardia, Inc. ,

Heart Failure 111

Heart Failure Quality of Life CMS Reimbursement 111

Circulation

NOVEMBER 11, 2024

Then, treadmill exercise tolerance test was performed, cardiac geometry, systolic and diastolic function were evaluated by echocardiography and heart and lungs were harvested. HFD/L-NAME mice showed altered exercise capacity (p&lt;0.05 vs. Ctrl), indicative of pulmonary congestion. in HFD/L-NAME vs E/A=1.4 ± 0.02

Preserved Ejection Fraction 40

Preserved Ejection Fraction Hypertension Blood Pressure Obesity 40