Remove Exercise Remove Preserved Ejection Fraction Remove Quality of Life
article thumbnail

Corvia's RESPONDER-HF Confirmatory Trial Supported by RELIEVE-HF Data

DAIC

RELIEVE-HF failed to meet its primary efficacy endpoint and did not reduce heart failure events or improve quality of life in heart failure patients with a preserved ejection fraction (HFpEF). For more information: www.corviamedical.com If you enjoy this content, please share it with a colleague

article thumbnail

Effects of Semaglutide on Symptoms, Function, and Quality of Life in Patients with Heart Failure with Preserved Ejection Fraction and Obesity: A Prespecified Analysis of the STEP-HFpEF Trial

Circulation

Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. mg improved symptoms, physical limitations and exercise function, and reduced inflammation and body weight. 5.4,16.1), 8.1

article thumbnail

Obesity in heart failure with preserved ejection fraction: Insights from the REDUCE LAP?HF II trial

European Journal of Heart Failure

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Pulmonary vascular resistance at rest and exercise decreased with higher BMI. Overall, 60.9% of patients had BMI ≥30 kg/m 2.

article thumbnail

Exercise training in heart failure

Heart BMJ

Learning objectives To understand the importance of exercise and physical activity in the general management and well-being of people with heart failure (HF). To understand the key principles of exercise training prescription in people with HF. cross-ref type="bib".

article thumbnail

Ninerafaxstat Well-Tolerated and Safe for Nonobstructive Hypertrophic Cardiomyopathy

DAIC

Maron, MD “Our findings provide enthusiasm that a novel drug therapy with ninerafaxstat may provide nonobstructive HCM patients an opportunity to achieve a better quality of life by decreasing symptom burden and improving exercise capacity,” said Martin S.

article thumbnail

Abstract 4118122: Effect of Beta Blockers on Exercise Capacity, Diastolic Function, and Quality of Life in Patients with Heart Failure with Preserved Ejection Fraction

Circulation

The primary outcomes were exercise capacity, diastolic function, and quality of life at baseline evaluation. After controlling for potential confounding variables, there were no differences in baseline exercise capacity [peak VO2 (mL/kg/min): 12.1 Patients were divided into two groups based on BB use at trial enrollment.