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Pulmonary arterial hypertension is a disease of the pulmonary vasculature, resulting in elevated pressure in the pulmonary arteries and disrupting the physiological coordination between the right heart and the pulmonary circulation. Journal of the American Heart Association, Ahead of Print.
Cardiopulmonary exercise testing is a valuable tool for assessing functional capacity, evaluating cardiac and pulmonary pathology, and providing guidance on prognosis and interventional recommendations. This is an updated report of the American Heart Association's previous publications on exercise in children.
Cardiovascular physiology has long held that the heart is a mechanical pump and that the heart’s propulsive power is the main driver of blood flow throughout the body. However, the cardiocentric view of circulation fails to explain blood flow regulation during exercise and other unique scenarios.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. There’s a long-running debate in exercisephysiology about what limits VO2 max. However, after 8 weeks of exercise training, the limitation of VO2 max shifts to oxygen transport.
Moreover, the definitions of elevated exercisepulmonary artery (PA) and PA wedge pressure (PAWP) for this population have not been described. There was no difference in exercise arterial O 2 saturation (87% [81;92] vs 89% [85;93], p = 0.29), while exercise PA pressure (27 [23;31] vs 16 [14.5;19.5]
Before continuing flecainide, he had me get on a treadmill at full dose and at full exercise (18 minutes) and measured the QRS to be certain that the QRS did not lengthen at all. It simply does not make physiologic sense to suddenly see an all-negative QRS complex in this most lateral chest lead. Coincidence?).
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