Dr. Paddy Barrett

APRIL 11, 2025

That factor is exercise. Mitochondria are the batteries of every cell in your body) Regular exercise has been repeatedly shown to improve mitochondrial function and prevent insulin resistance. And high levels of exercise are clearly linked to better mitochondrial function. Global Impacts Of Exercise. How Much Exercise?

Dementia 76

Dementia Exercise Cancer Heart Disease 76

Physiologically Speaking

MARCH 14, 2025

But this approach only applies to non-exercisers, right? Although structured exercise is imperative to achieve optimal health, recent evidence indicates it might not be enough to totally reverse the metabolic and cardiovascular consequences of too much sedentary time. Those of us who work out diligently don’t have to worry?

Physiology 75

Physiology Exercise Cardiovascular Disease Quality of Life 75

Open Heart

MARCH 28, 2025

Methods Relevant studies examining arrhythmia in both exercise and pharmacological stress testing were searched for in PubMed, Embase and Cochrane databases from inception to 14 June 2023. The primary outcomes of interest were mortality in ventricular and atrial arrhythmias, and later diagnosis of cardiac disease in atrial arrhythmias.

Arrhythmia 75

Arrhythmia Coronary Artery Disease Myocardial Infarction Atrial Fibrillation 75

Physiologically Speaking

OCTOBER 9, 2024

Researchers claim to have discovered “exercise in a pill” every few years, like clockwork. Inevitably the media becomes fascinated with this new molecule or pill and runs wild with headlines about how we have found a way to mimic exercise without all of the hard work (finally).

Exercise 75

Exercise Physiology Diet Obesity 75

Heart BMJ

OCTOBER 28, 2024

Burnout was a self-reported outcome. Exercise, good sleep quality and maintaining a healthy diet were associated with less burnout and depressive symptoms (p<0.05). Significant anxiety and depression were defined as scoring within the moderate or severe range (PHQ-9≥10; GAD-7≥10). to 0.92, p<0.01).

Patient Care 98

Patient Care Diet Exercise Outcomes 98

Journal of the American Heart Association

JANUARY 9, 2025

Cardiopulmonary exercise testing is a valuable tool for assessing functional capacity, evaluating cardiac and pulmonary pathology, and providing guidance on prognosis and interventional recommendations. This is an updated report of the American Heart Association's previous publications on exercise in children.

Congenital Heart Disease 75

Congenital Heart Disease Congenital Exercise Heart Disease 75

Dr. Paddy Barrett

JANUARY 2, 2025

Exercise Strategies For Reducing Risk. Setting exercise training zones. But if you want to increase your odds of a good outcome, the Heart Health Formula is a great place to start your journey. The Reducing Risk module includes lessons: Reversing Insulin Resistance Lowering LDL cholesterol without medications. Optimising Sleep.

Cholesterol 88

Cholesterol Heart Disease Blood Pressure Coronary Angiogram 88

Cardiometabolic Health Congress

FEBRUARY 10, 2025

. #1 Dietary Modifications: Evidence-Based Approaches Low-Fat vs. Low-Carb Diets A meta-analysis of 48 randomized controlled trials (RCTs) revealed no significant difference in weight loss outcomes between low-fat and low-carb diets. Practical Takeaway: Emphasize the role of exercise in improving metabolic health beyond weight loss.

Obesity 52

Obesity Diet Exercise Diabetes 52

Physiologically Speaking

DECEMBER 2, 2024

This meta-analysis explored whether exercise volume or intensity is more important for improving mitochondrial content, capillary density, and VO₂ max by compiling results from 425 training interventions involving over 5,600 participants, focusing on how different training intensities and volumes affect these key physiological adaptations.

Physiology 59

Physiology Exercise Dementia Genetic predisposition 59

NEJM Journal Watch - Cardiology

APRIL 30, 2024

The highly selective aldose reductase inhibitor AT-001 did not improve exercise capacity in a randomized trial.

Cardiomyopathy 81

Cardiomyopathy Diabetes Exercise Outcomes 81

Physiologically Speaking

JANUARY 5, 2024

Exercise prevents and reverses cardiovascular disease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Exercise is a wonder drug for cardiovascular disease (CVD) prevention and reversal. And the more you exercise, the better your outcomes.

Plaque 119

Plaque Physiology Exercise Cholesterol 119

MIBHS

DECEMBER 29, 2023

Exercise and heart health— you’ve probably heard of the correlation before. Engaging in exercise can significantly contribute to maintaining a healthy heart and reducing the risk of cardiovascular diseases. By addressing these risk factors, exercise significantly lowers the risk of developing cardiovascular diseases.

Exercise 52

Exercise Blood Pressure Risk Factors Cardiovascular Disease 52

American College of Cardiology

AUGUST 27, 2024

In patients who develop atrial fibrillation (AF), does the amount of previous lifetime hours of sport/exercise impact the form of AF, cardiovascular outcomes, and/or the need for cardioversion and ablation?

Exercise 40

Exercise Atrial Fibrillation Outcomes Ablation 40

DAIC

AUGUST 9, 2024

Researchers randomly grouped participants to receive either three days per week of 12 weeks of high-intensity interval training or three days per week of 12 weeks of traditional moderate exercise sessions. The moderate intensity continuous training involved 20 to 30 minutes of steady exercise at moderate intensity.

Exercise 52

Exercise Research Stroke Strokes 52

Frontiers in Cardiovascular Medicine

FEBRUARY 22, 2024

The purpose of the current study was to measure the efficacy of exercise on the physical ability, cardiac function and cardiopulmonary fitness of patients with AF. The results showed that physical exercise increased physical ability by improving the 6MWT (m) performance (MD = 96.99, 95% CI: 25.55–168.43; 3.24; Z  = 1.68; p  = 0.09).

Cardiac Function 64

Cardiac Function Exercise Atrial Fibrillation Quality of Life 64

Medical Xpress - Cardiology

MARCH 17, 2025

Exercise therapy has been shown to be particularly effective for patients with heart failure. Previous research, however, has mainly examined the benefits of exercise after a diagnosis of heart failure.

Heart Failure 40

Heart Failure Exercise Quality of Life Hospital 40

Circulation

NOVEMBER 8, 2024

BACKGROUND:Patients with hypertrophic cardiomyopathy without left ventricular outflow tract obstruction commonly experience reduced exercise capacity. Physical training improves exercise capacity in these patients, but whether the underlying effects of exercise are a result of central hemodynamic or peripheral improvement is unclear.

Exercise 49

Exercise Cardiomyopathy Quality of Life Pulmonary 49

Physiologically Speaking

JANUARY 24, 2025

1 If you want the tl;dr, here it is: After 6 weeks on either a low- or high-carb diet, athletes experienced similar performance outcomes during a time-to-exhaustion test , a result that vindicates low-carb diets once and for all. Nonetheless, the findings are one data point that should cause us to think differently about exercise metabolism.

Physiology 64

Physiology Diet Exercise BMI 64

DAIC

MAY 2, 2024

Results from the open label roll-in cohort of patients having chronic myocardial ischemia with refractory angina showed an average increase in exercise tolerance of 107 seconds and an average of 82% reduction in angina episodes at the primary six-month follow-up endpoint compared to before receiving the study treatment.

Ischemia 95

Ischemia Angina Heart Failure Outcomes 95

American College of Cardiology

JANUARY 17, 2024

In this week’s View, Dr. Eagle explores rethinking false positive exercise ECG Tests in patients with microvascular dysfunction. He then discusses a recent comparison of direct oral anticoagulants vs Vitamin K antagonists after transcatheter mitral valve replacement.

Exercise 55

Exercise Bicuspid/Mitral Outcomes Article 55

Circulation: Heart Failure

MARCH 5, 2025

BACKGROUND:Exercise-induced hypertension (EIH) is common in adults with coarctation of the aorta (COA), but there are limited data about hemodynamics and outcomes in such patients.

Exercise 40

Exercise Hypertension Outcomes Biomarkers 40

Medical Xpress - Cardiology

MARCH 19, 2025

Adult patients with congenital heart disease (CHD) have poor exercise capacity, which is associated with adverse outcomes.

Congenital Heart Disease 40

Congenital Heart Disease Congenital Exercise Heart Disease 40

Physiologically Speaking

DECEMBER 22, 2023

[link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role. Not only does exercise help to maintain a healthy weight and/or promote weight loss, but it can also keep cardiometabolic risk factors in check in the absence of weight loss. A 5-minute cooldown ended each session.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

[link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role. Not only does exercise help to maintain a healthy weight and/or promote weight loss, but it can also keep cardiometabolic risk factors in check in the absence of weight loss. A 5-minute cooldown ended each session.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Open Heart

JUNE 9, 2022

Background This review aimed to compare the relative effectiveness of different exercise-based cardiac rehabilitation (ExCR) delivery modes (centre-based, home-based, hybrid and technology-enabled ExCR) on key heart failure (HF) outcomes: exercise capacity, health-related quality of life (HRQoL), HF-related hospitalisation and HF-related mortality.

Quality of Life 52

Quality of Life Cardiac Rehabilitation Exercise Heart Failure 52

Physiologically Speaking

MARCH 15, 2024

These mice gained weight and had worse glucose control compared to mice on a normal schedule, but exercising prevented some of these changes. However, jetlagged mice didn’t experience the full extent of benefits due to exercise — their cardiorespiratory fitness was lower than mice who exercised but weren’t jetlagged.

Exercise 52

Exercise Physiology Blood Pressure Outcomes 52

Open Heart

APRIL 20, 2022

Objective To assess the feasibility, efficacy and safety of performing exercise stress echocardiography (ESE) for the assessment of myocardial ischaemia during the COVID-19 pandemic. Retrospective analysis was performed on follow-up data for outcomes. Service evaluation authorisation of research capability number SE20/059.

COVID-19 52

COVID-19 Exercise Coronary Artery Disease Echocardiogram 52

Journal of the American Heart Association

APRIL 10, 2025

Exercise testing has proven a useful tool to predict patient outcomes and even the need for reintervention in several cardiovascular disease processes. Our literature search yielded 122 relevant studies pertaining to exercise stress testing in pediatric heart disease.

Exercise 40

Exercise Congenital Heart Disease Congenital Heart Disease 40

Stroke Journal

JANUARY 30, 2025

Subgroup analyses were performed by exercise intensity and stroke onset, as well as separate analyses according to follow-up periods.Results:12 studies were included, encompassing 1,019 patients, with 54% undergoing HIT. Research has shown that physical rehabilitation can help improve these deficits to different extents.

Exercise 40

Exercise Stroke Strokes Outcomes 40

Heart BMJ

JULY 10, 2024

Despite improvements in outcomes, older adults with competing comorbidities and geriatric syndromes have suboptimal quality of life outcomes, highlighting the cumulative vulnerability that persists despite valve replacement. Exercise during the preoperative waiting period may be safe and effective in most patients with severe AS.

Aortic valve 98

Aortic valve Aortic Quality of Life TAVR 98

Physiologically Speaking

JUNE 7, 2024

Rather, every day provides an opportunity to allocate time to activities that can promote or detract from our health: how much we sleep, how much time we engage in exercise, and how much time we spend in sedentary activities like sitting. What’s the best way to spend our time when health is the outcome of interest?

Physiology 52

Physiology Exercise Blood Pressure Outcomes 52

Frontiers in Cardiovascular Medicine

FEBRUARY 28, 2024

Background As a therapy to prevent and treat essential hypertension (EH), traditional Chinese exercises (TCEs) were widely used in clinical practice. Weighted mean difference (WMD) was calculated for continuous outcomes. tool was utilized to evaluate the quality of the RCTs. The network meta-analysis was performed by R 4.1.2

Exercise 59

Exercise Blood Pressure Hypertension Outcomes 59

Dr. Paddy Barrett

DECEMBER 19, 2023

But can coronary artery disease be reversed with lifestyle measures, including changes to nutrition and exercise? In summary, the best outcome for plaque is to: Decrease in size Change from non calcified to calcified Develop a thick fibrous cap. After the six months, those in the exercise group had significantly less plaque 2.

Coronary Artery Disease 106

Coronary Artery Disease Plaque Exercise Heart Attack 106

MIBHS

JANUARY 15, 2025

Understanding how smoking affects the heart and raises surgery risks can empower individuals to make healthier choices and improve outcomes when surgical intervention is necessary. Poor healing can compromise the outcomes of bloodless surgeries, which rely on minimal incisions and precise techniques.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Blood Clot Blood Pressure Plaque 52

DAIC

JULY 10, 2024

Distinct racial and ethnic variations in baseline characteristics among patients with diabetic cardiomyopathy (DbCM), underscore the need for personalized and targeted strategies for managing overall care and outcomes.

Cardiomyopathy 113

Cardiomyopathy Diabetes Health Disparities Exercise 113

MIBHS

JANUARY 31, 2025

This blog explores the ways wearable technology can help track heart health, the advantages it offers, and how it contributes to better outcomes for those requiring surgical intervention. By identifying patterns, users can understand how their heart responds to exercise, stress, or relaxation.

Heart Rhythm 52

Heart Rhythm Technology AFIB Exercise 52

Heart BMJ

MARCH 22, 2024

Objective In Fontan circulation, pulmonary arterial hypertension (PAH)-targeted therapies could improve the patients’ exercise capacity. This study aimed to investigate the effects of PAH agents on different exercise parameters in stable Fontan patients by synthesising evidence of randomised controlled trials (RCTs).

Exercise 40

Exercise Circulation Pulmonary Pharmacology 40