Frontiers in Cardiovascular Medicine

APRIL 6, 2025

Higher RHR was significantly associated with an increased risk of adverse outcomes, but not with stroke (HR=0.999, 95% CI: 0.9911.007, P=0.7854) or cardiovascular death (HR=1.004, 95% CI: 0.9961.013, P=0.3504).

Atrial Fibrillation 52

Atrial Fibrillation Outcomes Myocardial Infarction Exercise 52

Physiologically Speaking

JUNE 14, 2024

Inflammation is also intricately tied to exercise. During exercise, our body mounts an acute inflammatory response, releasing all sorts of cytokines, macrophages, and other molecules throughout the circulation. The thing with exercise is that it also exerts an anti-inflammatory effect in the proceeding hours to days.

Exercise 104

Exercise Physiology Circulation Outcomes 104

Dr. Paddy Barrett

AUGUST 23, 2024

The evidence that high levels of exercise and subsequent fitness are linked with increased lifespan and health span is clear. By the end of this article, you should be convinced that high levels of fitness and daily exercise are a MUST for a longer quality of life without major illness. Here’s why. Enjoy the process.

Exercise 116

Exercise Dementia Cancer Chronic Disease 116

Physiologically Speaking

SEPTEMBER 20, 2024

In his book “ Exercised: why something we never evolved to do is healthy and rewarding ”, evolutionary biologist Daniel Lieberman coins the term —  exercists  — which he broadly defines as people who espouse the benefits, joys, and importance of regular exercise, sometimes to a fault.

Exercise 114

Exercise Physiology Blood Pressure Obesity 114

Physiologically Speaking

MARCH 14, 2025

But this approach only applies to non-exercisers, right? Although structured exercise is imperative to achieve optimal health, recent evidence indicates it might not be enough to totally reverse the metabolic and cardiovascular consequences of too much sedentary time. Those of us who work out diligently don’t have to worry?

Physiology 75

Physiology Exercise Cardiovascular Disease Quality of Life 75

Physiologically Speaking

MARCH 28, 2025

Research provides compelling evidence that endurance exercise, such as marathon running, may contribute to larger brain volumes than inactive or normally active individuals—they have larger grey matter, white matter, and total brain volumes than sedentary individuals. How exercise provides neuroprotection. I’m not so sure.

Exercise 71

Exercise Research Physiology Outcomes 71

Open Heart

MARCH 28, 2025

Methods Relevant studies examining arrhythmia in both exercise and pharmacological stress testing were searched for in PubMed, Embase and Cochrane databases from inception to 14 June 2023. The primary outcomes of interest were mortality in ventricular and atrial arrhythmias, and later diagnosis of cardiac disease in atrial arrhythmias.

Arrhythmia 75

Arrhythmia Coronary Artery Disease Myocardial Infarction Atrial Fibrillation 75

Physiologically Speaking

OCTOBER 9, 2024

Researchers claim to have discovered “exercise in a pill” every few years, like clockwork. Inevitably the media becomes fascinated with this new molecule or pill and runs wild with headlines about how we have found a way to mimic exercise without all of the hard work (finally).

Exercise 75

Exercise Physiology Diet Obesity 75

Heart BMJ

OCTOBER 28, 2024

Burnout was a self-reported outcome. Exercise, good sleep quality and maintaining a healthy diet were associated with less burnout and depressive symptoms (p<0.05). Significant anxiety and depression were defined as scoring within the moderate or severe range (PHQ-9≥10; GAD-7≥10). to 0.92, p<0.01).

Patient Care 98

Patient Care Diet Exercise Outcomes 98

Journal of the American Heart Association

JANUARY 9, 2025

Cardiopulmonary exercise testing is a valuable tool for assessing functional capacity, evaluating cardiac and pulmonary pathology, and providing guidance on prognosis and interventional recommendations. This is an updated report of the American Heart Association's previous publications on exercise in children.

Congenital Heart Disease 75

Congenital Heart Disease Congenital Exercise Heart Disease 75

Cardiometabolic Health Congress

FEBRUARY 10, 2025

. #1 Dietary Modifications: Evidence-Based Approaches Low-Fat vs. Low-Carb Diets A meta-analysis of 48 randomized controlled trials (RCTs) revealed no significant difference in weight loss outcomes between low-fat and low-carb diets. Practical Takeaway: Emphasize the role of exercise in improving metabolic health beyond weight loss.

Obesity 52

Obesity Diet Exercise Diabetes 52

Dr. Paddy Barrett

JANUARY 2, 2025

Exercise Strategies For Reducing Risk. Setting exercise training zones. But if you want to increase your odds of a good outcome, the Heart Health Formula is a great place to start your journey. The Reducing Risk module includes lessons: Reversing Insulin Resistance Lowering LDL cholesterol without medications. Optimising Sleep.

Cholesterol 84

Cholesterol Heart Disease Blood Pressure Coronary Angiogram 84

Physiologically Speaking

DECEMBER 2, 2024

This meta-analysis explored whether exercise volume or intensity is more important for improving mitochondrial content, capillary density, and VO₂ max by compiling results from 425 training interventions involving over 5,600 participants, focusing on how different training intensities and volumes affect these key physiological adaptations.

Physiology 59

Physiology Exercise Dementia Genetic predisposition 59

Dr. Paddy Barrett

NOVEMBER 15, 2024

The study found that the higher/better a person’s LE8 score was, the less likely each of these three outcomes was to occur. Those with excess weight who are eating well, sleeping well and exercising on a regular basis are also likely to reduce their harmful visceral fat. Died from heart disease. We know this works.

Heart Disease 98

Heart Disease Obesity Blood Pressure Cholesterol 98

NEJM Journal Watch - Cardiology

APRIL 30, 2024

The highly selective aldose reductase inhibitor AT-001 did not improve exercise capacity in a randomized trial.

Cardiomyopathy 81

Cardiomyopathy Diabetes Exercise Outcomes 81

Physiologically Speaking

JANUARY 5, 2024

Exercise prevents and reverses cardiovascular disease, but whether high-intensity exercise training (HIIT) is safe and effective for adults after minimally invasive heart surgery is unknown. Exercise is a wonder drug for cardiovascular disease (CVD) prevention and reversal. And the more you exercise, the better your outcomes.

Plaque 119

Plaque Physiology Exercise Cholesterol 119

MIBHS

DECEMBER 29, 2023

Exercise and heart health— you’ve probably heard of the correlation before. Engaging in exercise can significantly contribute to maintaining a healthy heart and reducing the risk of cardiovascular diseases. By addressing these risk factors, exercise significantly lowers the risk of developing cardiovascular diseases.

Exercise 52

Exercise Blood Pressure Risk Factors Cardiovascular Disease 52

American College of Cardiology

AUGUST 27, 2024

In patients who develop atrial fibrillation (AF), does the amount of previous lifetime hours of sport/exercise impact the form of AF, cardiovascular outcomes, and/or the need for cardioversion and ablation?

Exercise 40

Exercise Atrial Fibrillation Outcomes Ablation 40

DAIC

AUGUST 9, 2024

Researchers randomly grouped participants to receive either three days per week of 12 weeks of high-intensity interval training or three days per week of 12 weeks of traditional moderate exercise sessions. The moderate intensity continuous training involved 20 to 30 minutes of steady exercise at moderate intensity.

Exercise 52

Exercise Research Strokes Stroke 52

DAIC

MARCH 25, 2025

Ten presentations will feature new data from the pivotal Phase III FINEARTS-HF cardiovascular (CV) outcomes trial, which investigated KERENDIA for treatingt adult patients with heart failure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF). Additional ACC.25

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Kidney Disease Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 22, 2024

The purpose of the current study was to measure the efficacy of exercise on the physical ability, cardiac function and cardiopulmonary fitness of patients with AF. The results showed that physical exercise increased physical ability by improving the 6MWT (m) performance (MD = 96.99, 95% CI: 25.55–168.43; 3.24; Z  = 1.68; p  = 0.09).

Cardiac Function 64

Cardiac Function Exercise Atrial Fibrillation Quality of Life 64

Medical Xpress - Cardiology

MARCH 17, 2025

Exercise therapy has been shown to be particularly effective for patients with heart failure. Previous research, however, has mainly examined the benefits of exercise after a diagnosis of heart failure.

Heart Failure 40

Heart Failure Exercise Quality of Life Hospital 40

American College of Cardiology

JANUARY 17, 2024

In this week’s View, Dr. Eagle explores rethinking false positive exercise ECG Tests in patients with microvascular dysfunction. He then discusses a recent comparison of direct oral anticoagulants vs Vitamin K antagonists after transcatheter mitral valve replacement.

Exercise 58

Exercise Bicuspid/Mitral Outcomes Article 58

Circulation

NOVEMBER 8, 2024

BACKGROUND:Patients with hypertrophic cardiomyopathy without left ventricular outflow tract obstruction commonly experience reduced exercise capacity. Physical training improves exercise capacity in these patients, but whether the underlying effects of exercise are a result of central hemodynamic or peripheral improvement is unclear.

Exercise 49

Exercise Cardiomyopathy Quality of Life Pulmonary 49

Physiologically Speaking

JANUARY 24, 2025

1 If you want the tl;dr, here it is: After 6 weeks on either a low- or high-carb diet, athletes experienced similar performance outcomes during a time-to-exhaustion test , a result that vindicates low-carb diets once and for all. Nonetheless, the findings are one data point that should cause us to think differently about exercise metabolism.

Physiology 64

Physiology Diet Exercise BMI 64

DAIC

MAY 2, 2024

Results from the open label roll-in cohort of patients having chronic myocardial ischemia with refractory angina showed an average increase in exercise tolerance of 107 seconds and an average of 82% reduction in angina episodes at the primary six-month follow-up endpoint compared to before receiving the study treatment.

Ischemia 95

Ischemia Angina Heart Failure Outcomes 95

Circulation: Heart Failure

MARCH 5, 2025

BACKGROUND:Exercise-induced hypertension (EIH) is common in adults with coarctation of the aorta (COA), but there are limited data about hemodynamics and outcomes in such patients.

Exercise 40

Exercise Hypertension Outcomes Biomarkers 40

Medical Xpress - Cardiology

MARCH 19, 2025

Adult patients with congenital heart disease (CHD) have poor exercise capacity, which is associated with adverse outcomes.

Congenital Heart Disease 40

Congenital Heart Disease Congenital Exercise Heart Disease 40

Physiologically Speaking

DECEMBER 22, 2023

[link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role. Not only does exercise help to maintain a healthy weight and/or promote weight loss, but it can also keep cardiometabolic risk factors in check in the absence of weight loss. A 5-minute cooldown ended each session.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

[link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role. Not only does exercise help to maintain a healthy weight and/or promote weight loss, but it can also keep cardiometabolic risk factors in check in the absence of weight loss. A 5-minute cooldown ended each session.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Open Heart

JUNE 9, 2022

Background This review aimed to compare the relative effectiveness of different exercise-based cardiac rehabilitation (ExCR) delivery modes (centre-based, home-based, hybrid and technology-enabled ExCR) on key heart failure (HF) outcomes: exercise capacity, health-related quality of life (HRQoL), HF-related hospitalisation and HF-related mortality.

Quality of Life 52

Quality of Life Cardiac Rehabilitation Exercise Heart Failure 52

Physiologically Speaking

MARCH 15, 2024

These mice gained weight and had worse glucose control compared to mice on a normal schedule, but exercising prevented some of these changes. However, jetlagged mice didn’t experience the full extent of benefits due to exercise — their cardiorespiratory fitness was lower than mice who exercised but weren’t jetlagged.

Exercise 52

Exercise Physiology Blood Pressure Outcomes 52

Open Heart

APRIL 20, 2022

Objective To assess the feasibility, efficacy and safety of performing exercise stress echocardiography (ESE) for the assessment of myocardial ischaemia during the COVID-19 pandemic. Retrospective analysis was performed on follow-up data for outcomes. Service evaluation authorisation of research capability number SE20/059.

COVID-19 52

COVID-19 Exercise Coronary Artery Disease Echocardiogram 52

Stroke Journal

JANUARY 30, 2025

Subgroup analyses were performed by exercise intensity and stroke onset, as well as separate analyses according to follow-up periods.Results:12 studies were included, encompassing 1,019 patients, with 54% undergoing HIT. Research has shown that physical rehabilitation can help improve these deficits to different extents.

Exercise 40

Exercise Strokes Stroke Outcomes 40

Heart BMJ

JULY 10, 2024

Despite improvements in outcomes, older adults with competing comorbidities and geriatric syndromes have suboptimal quality of life outcomes, highlighting the cumulative vulnerability that persists despite valve replacement. Exercise during the preoperative waiting period may be safe and effective in most patients with severe AS.

Aortic valve 98

Aortic valve Aortic Quality of Life TAVR 98

DAIC

MAY 16, 2024

A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Physiologically Speaking

JUNE 7, 2024

Rather, every day provides an opportunity to allocate time to activities that can promote or detract from our health: how much we sleep, how much time we engage in exercise, and how much time we spend in sedentary activities like sitting. What’s the best way to spend our time when health is the outcome of interest?

Exercise 52

Exercise Physiology Blood Pressure Outcomes 52