Physiologically Speaking

MARCH 6, 2024

Plenty of people love to exercise. But the disheartening truth is that most people don’t enjoy exercise. A third or less of adults meet the minimum recommendations for aerobic and strength exercise each week. I’m an exercise scientist by training. We can promote exercise until we’re red in the face.

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Exercise Blood Pressure Risk Factors Physiology 92

Physiologically Speaking

OCTOBER 9, 2024

Researchers claim to have discovered “exercise in a pill” every few years, like clockwork. Inevitably the media becomes fascinated with this new molecule or pill and runs wild with headlines about how we have found a way to mimic exercise without all of the hard work (finally).

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Exercise Physiology Diet Obesity 75

Circulation: Heart Failure

SEPTEMBER 12, 2023

We defined HFpEF based on the presence of elevated left ventricular filling pressures at rest or during exercise. Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. mL/kg per min lower peak VO2(β, −2.35±0.19;P<0.001). P<0.001).

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Biomarkers Obesity Exercise Preserved Ejection Fraction 40

Physiologically Speaking

FEBRUARY 14, 2025

A few months ago ago, I wrote about a pair of studies showing that “weekend warriors”—those who concentrate their weekly exercise into one or two days— can achieve health benefits comparable to those who spread their activity throughout the week. How frequently one exercises may not be as important as how much.

Physiology 85

Physiology Exercise Research Dementia 85

Dr. Paddy Barrett

JULY 19, 2024

So, I decided to track my calories, macros and exercise more carefully over the next few weeks, which soon got me to my target. The same holds true for exercise-based interventions. It's not that the exercise stopped working. It’s that people stopped exercising. Just like exercise is a tool. may be necessary.

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Exercise Diet Obesity Risk Factors 108

CardiacWire

AUGUST 14, 2024

Rivus Pharmaceuticals’ HU6 is showing promise as a future obesity-related HFpEF treatment, after topline results from its Phase 2a HuMAIN trial revealed valuable weight, symptom, and cardiometabolic improvements – without the risk of muscle loss. The post Rivus HU6 Shows Obesity-HFpEF Potential appeared first on Cardiac Wire.

Obesity 52

Obesity Diet Quality of Life Blood Pressure 52

HCPLive

MARCH 13, 2025

The novel controlled metabolic accelerator significantly reduced fat-specific body weight but showed no improvements in exercise capacity over 19 weeks.

Obesity 59

Obesity Exercise 59

MIBHS

DECEMBER 29, 2023

Exercise and heart health— you’ve probably heard of the correlation before. Engaging in exercise can significantly contribute to maintaining a healthy heart and reducing the risk of cardiovascular diseases. By addressing these risk factors, exercise significantly lowers the risk of developing cardiovascular diseases.

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Exercise Blood Pressure Risk Factors Cardiovascular Disease 52

Medical Xpress - Cardiology

JANUARY 17, 2024

A robust body of evidence shows aerobic exercise can reduce risks, especially for people who are overweight or obese. Approximately one in three deaths in the U.S. is caused by cardiovascular disease, according to the U.S. Centers for Disease Control and Prevention.

Cardiovascular Disease 81

Cardiovascular Disease Research Obesity Exercise 81

Cardiometabolic Health Congress

JULY 25, 2023

Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.

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Obesity BMI Heart Failure Cardiovascular Disease 52

Physiologically Speaking

JANUARY 31, 2025

I’m voluntarily retiring, and turning the reins over to Brady Holmer, writer, exercise physiologist, and 2:26 marathon runner. More at International J of Exercise Science with free full text. ” In other words, all exercise was weight-bearing. He was my first pick for the job. That’s a big change.

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Physiology Exercise Article Research 85

Dr. Paddy Barrett

AUGUST 9, 2024

The 14 Factors Include: Hearing Loss High LDL cholesterol Less Education Traumatic Brain Injury Depression Social Isolation Hypertension Obesity Smoking Excess Alcohol Diabetes Physical Inactivity Air Pollution Visual Loss Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission When You Intervene Matters.

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Dementia Blood Pressure Obesity Cholesterol 114

American College of Cardiology

JANUARY 24, 2024

The goal of the CardioRACE trial was to evaluate different exercise strategies compared with control among patients with overweight/obesity.

Exercise 41

Exercise Obesity Article 41

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

Atrial fibrillation (AF), the most prevalent cardiac arrhythmia, is closely linked to metabolic dysfunctions, including obesity, diabetes, and dyslipidemia. Additionally, it calls for more basic studies and large-scale clinical trials to establish and refine evidence-based exercise guidelines specific to AF management.

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Atrial Fibrillation Exercise Pharmacology Obesity 40

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

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Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol. link] Of course, diet is an important component of metabolic health, but exercise also plays an indispensable role.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

HeartRhythm

APRIL 30, 2024

The obesity-HFpEF phenotype is a unique form of heart failure associated with elevated LA and RA pressures, cardiac remodelling and poor exercise capacity. The influence of this HFpEF phenotype amongst patients with AF is unknown.

Obesity 40

Obesity Heart Failure Exercise 40

Dr. Paddy Barrett

APRIL 5, 2024

It is a structured education and exercise program that helps people understand what has just happened to them and helps them get all the lifestyle and medical pieces together to reduce the future risk of a major heart event. Regular exercise and hitting LDL-C targets of <1.4 Share Reverse Coronary Artery Disease. Br J Gen Pract.

Heart Disease 117

Heart Disease Coronary Artery Disease Heart Attack Heart attacks 117

DAIC

JUNE 18, 2024

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8

Heart Disease 105

Heart Disease Blood Pressure Stroke Strokes 105

MIBHS

MARCH 15, 2025

Additionally, alcohol contributes to weight gain, as many alcoholic beverages are high in empty calories, leading to an increased risk of obesity and its associated heart complications. Other lifestyle factors, such as a healthy diet, regular exercise, and stress management, also play significant roles in maintaining heart health.

Blood Pressure 52

Blood Pressure Heart Rhythm Blood Clot Heart Disease 52

European Journal of Heart Failure

DECEMBER 7, 2023

Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. Overall, 60.9%

Preserved Ejection Fraction 40

Preserved Ejection Fraction Obesity Heart Failure BMI 40

Dr. Paddy Barrett

APRIL 12, 2024

But for many people regular exercise at even moderate intensities will not be on the cards. More steps are linked to: Less obesity. Maybe you are one of the fortunate ones who loves to exercise at a high level and has managed to land in the top 2.5% occupation-related physical activity and their associations with obesity.

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Quality of Life Blood Pressure Exercise Chronic Disease 124

MIBHS

FEBRUARY 15, 2025

Exercise Regularly : Aim for at least 150 minutes of moderate-intensity aerobic activity per week, such as walking, cycling, or swimming. Exercise strengthens your heart and improves its efficiency, reducing blood pressure levels over time. Limit Alcohol and Avoid Tobacco : Drinking excessive alcohol can raise your blood pressure.

Blood Pressure 52

Blood Pressure Hypertension Chest Pain Aneurysm 52

Dr. Paddy Barrett

AUGUST 30, 2024

At the bottom are the four pillars of a good lifestyle: exercise, nutrition, sleep and stress. Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. Obesity is one of the biggest global health concerns we face today. Obesity is also a key driver of risk for cardiovascular disease. Obesity (Silver Spring).

Heart Disease 111

Heart Disease Dementia Obesity Heart Attack 111

MIBHS

FEBRUARY 28, 2025

While much attention is given to modifiable risk factors such as diet, exercise, and smoking, the role of genetics in heart disease is equally critical yet less understood by the general public. Exercise: Regular physical activity strengthens the heart and improves blood circulation.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

DECEMBER 12, 2023

That’s what the field of obesity therapeutics feels like right now. What was once an area of healthcare that had few reliable interventions, this drug class has revolutionised the management of excess weight and obesity. Subscribe now 1 [link] 2 [link] 3 Retatrutide Phase 2 Obesity Trial Investigators. N Engl J Med.

Obesity 105

Obesity Heart Attack Heart attacks Diet 105

Dr. Paddy Barrett

MAY 24, 2024

The DPP is a year-long program involving multiple group coaching sessions that focuses primarily on improving: Nutrition Exercise Stress Management. However, for those who used both nutrition AND exercise as their strategy, the risk of death from any cause fell by 28% 5. ” Diabetes. Does weight loss work in these cases?

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Diabetes Diet BMI Exercise 108

Cardiometabolic Health Congress

JANUARY 28, 2025

Obesity management beyond diet and exercise. Sleep and Cardiometabolic Health The Impact on Obesity Studies indicate that 19.3% of adults experience insufficient sleep (6 hours), which is linked to higher obesity rates. Practical Takeaway Recommend stress-reducing practices like yoga or mindfulness exercises.

Obesity 52

Obesity Diet Exercise Education 52

Circulation

NOVEMBER 17, 2024

Background: Patients with heart failure, a preserved ejection fraction (HFpEF), and obesity have significant disability and suffer frequent exacerbations of heart failure. Circulation, Ahead of Print. The broad spectrum of effects was reflected in benefits on the hierarchical composite (win ratio 1.63, 95%CI, 1.17, 2.28;P=0.004).Conclusions:

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Obesity Quality of Life 40

Circulation

NOVEMBER 11, 2024

This study aims to establish the effect of an active lifestyle in paediatric Fontan patients, determine its relationship with body composition, exercise capacity, ventricle function and quality of life.Methods:30 Fontan patients were recruited. Overall BMI was normal, however 17% (5 of 30) were overweight or obese (Table 1).The

Quality of Life 40

Quality of Life Exercise Circulation Congenital Heart Disease 40

AMS Cardiology

MARCH 31, 2025

Obesity : Excess weight increases the risk of heart-related issues, including AFib. How to Stop AFib: Lifestyle Modifications In addition to medical treatments, certain lifestyle changes can help manage and potentially reduce AFib episodes: Regular Exercise : Engaging in moderate physical activity strengthens the heart.

Atrial Fibrillation 52

Atrial Fibrillation AFIB Heart Rhythm Blood Pressure 52

Circulation

NOVEMBER 11, 2023

Background:Patients with heart failure (HF) with preserved ejection fraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. mg improved symptoms, physical limitations and exercise function, and reduced inflammation and body weight. mg or placebo for 52 weeks.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Quality of Life Obesity Heart Failure 40

Cardiometabolic Health Congress

JUNE 27, 2024

Competence in selecting treatments for long-term obesity management rose from 43% pre-test to 95% post-test. Neha Agarwal, PhD, Clinical Director at Cardiometabolic Health Congress , Informa Connect, recently presented significant findings at the 84th American Diabetes Association (ADA) Scientific Sessions.

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CME Diabetes Obesity Education 59

Circulation

JANUARY 22, 2025

Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. In our study, NT-proBNP provided little value in those with AF and dyspnea because the presence of AF is by itself a robust biomarker of HFpEF.

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Preserved Ejection Fraction Outpatient Heart Failure BMI 55

Physiologically Speaking

NOVEMBER 29, 2023

However, newer research has failed to replicate these findings, showing no performance enhancement in longer-duration endurance events with ketone esters and, in some cases, observing a negative impact on high-intensity exercise performance. What are ketone esters, also referred to as exogenous ketones? More on this later.

Exercise 52

Exercise Diet Physiology Obesity 52

Physiologically Speaking

NOVEMBER 29, 2023

However, newer research has failed to replicate these findings, showing no performance enhancement in longer-duration endurance events with ketone esters and, in some cases, observing a negative impact on high-intensity exercise performance. What are ketone esters, also referred to as exogenous ketones? More on this later.

Exercise 52

Exercise Diet Physiology Obesity 52

Dr. Paddy Barrett

AUGUST 16, 2024

Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. So What Is The Efficacy Of Diet & Exercise For Weight Loss? ” here is what I tell them.

Obesity 52

Obesity Blood Pressure Diet Exercise 52