Physiologically Speaking

JULY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This irregular sleep pattern misaligns circadian rhythms and disrupts physiology. ICYMI: On Wednesday, I published my video interview with Dr. Andrew Koutnik. “The shorter your sleep, the shorter your life.”

Chronic Disease 64

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 64

European Journal of Heart Failure

DECEMBER 28, 2023

Moreover, the definitions of elevated exercise pulmonary artery (PA) and PA wedge pressure (PAWP) for this population have not been described. There was no difference in exercise arterial O 2 saturation (87% [81;92] vs 89% [85;93], p = 0.29), while exercise PA pressure (27 [23;31] vs 16 [14.5;19.5] All rights reserved.

Exercise 40

Exercise Physiology Article Pulmonary 40

MIBHS

JANUARY 31, 2025

The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. By identifying patterns, users can understand how their heart responds to exercise, stress, or relaxation. This reduces the likelihood of complications during and after the procedure.

Heart Rhythm 52

Heart Rhythm Technology AFIB Exercise 52

Dr. S. Venkatesan MD

NOVEMBER 29, 2023

Many times , an Innocuous question poses a real challenge, to our life time understanding of circulatory physiology. In patients with associated supine hypertension, the criteria for orthostatic hypotension allows for a drop of at least 30 mm Hg in SBP or 15 mm Hg in DBP. Next question What happens to BP during exercise ?

Blood Pressure 52

Blood Pressure Hypertension POTS Physiology 52

MIBHS

NOVEMBER 30, 2023

The exact mechanisms behind this link are complex, but it’s believed that the combination of lifestyle factors associated with depression (such as poor diet, lack of exercise, and smoking) and the physiological effects of depression on the body (including inflammation and blood clotting) can contribute to heart problems.

Blood Pressure 52

Blood Pressure Heart Disease Blood Clot Physiology 52

Circulation

NOVEMBER 11, 2024

g/L of an iNOS inhibitor (N-Nitro-L-arginine methylester) to induce hypertension. After 5 weeks of the diet, HFD mice and their littermate controls underwent baseline exercise testing and echocardiograms. Gene and protein expression studies in heart tissue are underway. Further work is warranted with a larger sample size.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Echocardiogram Exercise Diet 40

Physiologically Speaking

MARCH 29, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. There’s a surge in research devoted to finding the best time to exercise. These results suggests that more attention should be paid to the idea of “chrono-exercise” for health and disease management.

Blood Pressure 52

Blood Pressure Exercise Physiology Hypertension 52

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. On Monday, I posted a video summary of the recently released Scientific Statement by the American Heart Association (AHA) on resistance exercise training for cardiovascular health.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. On Monday, I posted a video summary of the recently released Scientific Statement by the American Heart Association (AHA) on resistance exercise training for cardiovascular health.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

FEBRUARY 14, 2024

As we age, we have lower levels of nitric oxide (NO), leading to endothelial dysfunction , arterial stiffening, and a rise in blood pressure (hypertension) — three of the primary causes of cardiovascular disease. Increasing levels of NO in the body can be accomplished by supplementing with nitrates in the form of beetroot juice.

Blood Pressure 97

Blood Pressure Diet Exercise Cardiovascular Disease 97

Physiologically Speaking

OCTOBER 4, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. I used to believe a lot of things about exercise. For a long time, I believed that to get the benefits of exercise, one needs to complete it in bouts of 30–60 minutes or more. Is this optimal? Certainly not.

Exercise 105

Exercise Physiology Dementia Obesity 105

Cardiometabolic Health Congress

MAY 10, 2024

Results revealed that women are twice as likely to exhibit myocardial ischemia in response to mental stress compared to traditional stressors like exercise or pharmacologic stress. After a normal stress test, coronary physiology testing revealed endothelial dysfunction with coronary vasospasm.

Coronary Artery Disease 59

Coronary Artery Disease Obesity Chest Pain Ischemia 59

Physiologically Speaking

APRIL 24, 2024

6 [link] Insufficient sleep has been linked to a greater risk for several health conditions including obesity, diabetes, hypertension, and cognitive decline. Multiple studies find that the risk for high blood pressure (hypertension) is elevated in women with short sleep duration to a greater extent than it is in men.

Blood Pressure 52

Blood Pressure Blood Clot COVID-19 Cardiovascular Disease 52

Physiologically Speaking

DECEMBER 17, 2024

While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. This has raised concerns that long-term, high-volume exercise might be detrimental to heart health.

Risk Factors 105

Risk Factors Genetic predisposition Plaque Exercise 105

Dr. S. Venkatesan MD

MARCH 17, 2025

The classical illustrations that are found in cardiac physiology literature about the dominance of coronary blood flow during diastole (Image source Ref 2) Instead, coronary perfusion pressure, mean coronary arterial pressure, and coronary arterial wedge pressure are discussed. Why systemic hypertension is a weak coronary risk factor ?

Angina 59

Angina Physiology Cardiomyopathy Aortic 59