Nature Reviews - Cardiology

APRIL 9, 2025

Nature Reviews Cardiology, Published online: 10 April 2025; doi:10.1038/s41569-025-01156-9 Findings from the BHF PROTECT-TAVI trial indicate that the routine use of cerebral embolic protection devices during transcatheter aortic valve implantation does not decrease the incidence of stroke within 72 h after the intervention.

Embolism 46

Embolism Aortic valve Strokes Stroke 46

Med Page Today

JUNE 5, 2024

(MedPage Today) -- NEW YORK CITY -- Researchers eked out evidence of a small clinical benefit with the Sentinel cerebral embolic protection (CEP) device in transcatheter aortic valve replacement (TAVR) -- and pointed to the patients more likely.

TAVR 105

TAVR Aortic valve Embolism Aortic 105

Journal of Cardiothoracic Surgery

JUNE 26, 2024

Although rare, paradoxical embolism sometimes occurs with patent ductus arteriosus (PDA). This study presents a case of PDA-associated paradoxical embolism with acute ischemic stroke (AIS) and pulmonary emboli.

Embolism 52

Embolism Pulmonary Strokes Stroke 52

Frontiers in Cardiovascular Medicine

APRIL 3, 2025

BackgroundNon-valvular atrial fibrillation (NVAF) significantly increases ischemic stroke and systemic embolism (SE) risks. for stroke/SE-specific, p-value<0.001). Despite the proven efficacy of oral anticoagulants (OAC) in reducing these risks, their underutilization highlights a gap in clinical practice.

Atrial Fibrillation 52

Atrial Fibrillation Hospital Dementia Embolism 52

Med Page Today

MARCH 30, 2025

(MedPage Today) -- CHICAGO -- Routine use of devices to prevent cerebral emboli during transcatheter aortic valve implantation (TAVI) did not prevent strokes, a large randomized trial showed. Incidence of stroke within 72 hours after TAVI or.

Aortic valve 52

Aortic valve Embolism Strokes Stroke 52

HCPLive

SEPTEMBER 1, 2024

Asundexian failed to prove noninferiority to apixaban for its primary efficacy outcome in the phase 3 OCEANIC-AF trial.

Embolism 69

Embolism Strokes Stroke Outcomes 69

HeartRhythm

APRIL 30, 2024

AF detection rates with implantable cardiac monitoring (ICM) following cryptogenic stroke are >12% at 12 months. Similar results have been reported in some non-cryptogenic stroke cohorts. Real-world data has also shown a much lower rate of AF detection.

Embolism 40

Embolism Strokes Stroke Atrial Fibrillation 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP388-ATP388, February 1, 2025. Introduction:Embolic Stroke of Undetermined Source (ESUS) accounts for a critical proportion of all ischemic strokes. Disambiguating embolism etiology is important to improve treatment efficacy and reduce recurrent events.

Embolism 40

Embolism Strokes Stroke Outcomes 40

Journal of Cardiothoracic Surgery

APRIL 7, 2024

Pulmonary embolism is the most common cardiovascular disease after myocardial infarction and stroke. Konstantinides (Eur Heart J 41(4):543–603, 2020) Current guidelines categorize patients with PE as being at.

Embolism 52

Embolism Pulmonary Myocardial Infarction Cardiovascular Disease 52

Heart BMJ

MAY 10, 2024

Objectives The use of cerebral embolic protection (CEP) during transcatheter aortic valve implantation (TAVI) has been studied in several randomised trials. We aimed to perform a systematic review and Bayesian meta-analysis of randomised CEP trials, focusing on a clinically relevant reduction in disabling stroke.

Aortic valve 52

Aortic valve Embolism Aortic Strokes 52

The New England Journal of Medicine

MARCH 29, 2025

In a randomized trial, the routine use of cerebral embolic protection during TAVI did not reduce the incidence of stroke within 72 hours or before discharge from the hospital (if discharge occurred sooner).

Embolism 40

Embolism Aortic valve Aortic Hospital 40

HCPLive

MARCH 27, 2025

OAC-naive patients experienced a significantly smaller increase in stroke or systemic embolism with asundexian than apixaban.

Strokes 52

Strokes Stroke Embolism 52

HeartRhythm

APRIL 30, 2024

The association between AF detected by implanted cardiac implantable electronic devices (CIEDs) and the incidence of embolic stroke has been reported. Moreover, the cut-off value of new-onset AF duration detected by CIEDs for embolic stroke is still unknown.

Atrial Fibrillation 40

Atrial Fibrillation Embolism Cancer Strokes 40

HeartRhythm

APRIL 30, 2024

Atrial fibrillation (AF) has been known as a main cause of embolic stroke. Well-chosen candidate to be anticoagulated should be critical for secondary prevention in patients with embolic stroke with undetermined source (ESUS).

Atrial Fibrillation 40

Atrial Fibrillation Embolism Strokes Stroke 40

American College of Cardiology

MARCH 30, 2025

Use of a cerebral embolic protection (CEP) device did not decrease the incidence of stroke within 72 hours after participants underwent TAVI, according to new research presented during a Late-Breaking Clinical Trial session at ACC.25 25 in Chicago and simultaneously published in NEJM.

Strokes 52

Strokes Stroke Embolism Research 52

ECG Cases

SEPTEMBER 12, 2023

The post ECG Cases 45 ECG in Weakness and Neurological Symptoms appeared first on Emergency Medicine Cases.

Dysrhythmia 135

Dysrhythmia Atrial Fibrillation Embolism Blog 135

Frontiers in Cardiovascular Medicine

DECEMBER 20, 2023

Massive pulmonary embolism (MPE) carries significant 30-day mortality and is characterized by acute right ventricular failure, hypotension, and hypoxia, leading to cardiovascular collapse and cardiac arrest. Considerable heterogeneity in studies is a significant weakness of the available literature.

Embolism 56

Embolism Pulmonary Cardiac Arrest Hemorrhage 56

Stroke: Vascular and Interventional Neurology

AUGUST 24, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. Middle meningeal artery embolization is an increasingly common procedure involved in the treatment of chronic subdural hematoma (cSDH) that can be an adjuvant intervention or an alternative to traditional medical or surgical therapies.

Embolism 40

Embolism Strokes Stroke 40

Journal of the American Heart Association

NOVEMBER 28, 2023

BackgroundDisambiguation of embolus pathogenesis in embolic strokes is often a clinical challenge. One common source of embolic stroke is the carotid arteries, with emboli originating due to plaque buildup or perioperatively during revascularization procedures.

Embolism 40

Embolism Strokes Stroke Plaque 40

Frontiers in Cardiovascular Medicine

APRIL 3, 2025

Except for 2 cases (1.4%) of micropericardial effusion, there were no other complications such as cardiac tamponade, major bleeding, stroke oroccluder embolization. The procedural success rate was 99.3%. During the 12-month follow-up, serious adverse events occurred in 3 patients (2.2%), all of which were device-related thrombus (DRT).

Embolism 52

Embolism Strokes Stroke 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP259-ATP259, February 1, 2024. Background and Purpose:Right-to-left shunt (RLS) is one of the potential embolic sources in embolic stroke of undetermined source (ESUS), but the eligibility of conducting shunt study to detect RLS in ESUS is still unknown. cm/s, p = 0.021).

Embolism 40

Embolism Bicuspid/Mitral Circulation Strokes 40

DAIC

MARCH 26, 2024

Addressing the serious issue of delayed and missed findings in diagnostic imaging, CINA-iPE is an AI-powered tool that detects incidental pulmonary embolism during routine CT scans. This is particularly relevant in the cancer patient population, where pulmonary embolism is a significant cause of mortality.

Embolism 105

Embolism Pulmonary Blood Clot Cancer 105

The New England Journal of Medicine

JANUARY 1, 2025

A randomized trial of the factor XIa inhibitor asundexian was stopped early owing to a higher incidence of stroke or systemic embolism than with apixaban therapy among patients with atrial fibrillation.

Atrial Fibrillation 75

Atrial Fibrillation Embolism Strokes Stroke 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP214-AWP214, February 1, 2024. Introduction:Middle meningeal artery embolization for chronic subdural hematomas is a promising treatment either as an adjuvant to surgical evacuation of the hematoma or as a primary treatment modality. The mean maximal diameter of the collection was 16.3 ± 6.6

Embolism 40

Embolism Strokes Stroke Outcomes 40

Frontiers in Cardiovascular Medicine

FEBRUARY 4, 2024

Anticoagulation is the mainstay of stroke prevention in appropriate patients with atrial fibrillation. An investigational class of agents which inhibit Factor XI have shown promise in pre-clinical and early clinical trials to significantly minimize bleeding while maintaining efficacy against stroke and systemic embolism.

Atrial Fibrillation 97

Atrial Fibrillation Embolism Strokes Stroke 97

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP98-AWMP98, February 1, 2025. Background:The use of oral anticoagulation (OAC) for stroke prevention in embolic stroke of undetermined source (ESUS) is hypothesized to be beneficial over conventional antiplatelet use. A random-effects model was used for the analyses. RevMan Web).Results:14,582

Embolism 40

Embolism Strokes Stroke Cardiomyopathy 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A42-A42, February 1, 2024. Introduction:A new Plaque-RADS classification (I-IV) is proposed to categorize the degree of carotid plaque instability and risk of embolic ischemic stroke. Carotid total plaque thickness and ulceration were scored by a neuroradiologist blinded to stroke side.

Plaque 40

Plaque Embolism Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP223-ATP223, February 1, 2024. Background:A considerable portion of patients with embolic stroke of unknown source(ESUS)are later found to have occult atrial fibrillation (AF).

Atrial Fibrillation 40

Atrial Fibrillation Embolism Strokes Stroke 40

Journal of the American Heart Association

APRIL 17, 2025

BackgroundNonvitamin K oral anticoagulants prevent stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Journal of the American Heart Association, Ahead of Print.

Atrial Fibrillation 40

Atrial Fibrillation Hemorrhage Embolism Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP262-ATP262, February 1, 2025. Introduction:Fibrocartilaginous embolism (FCE) is a rare etiology of spinal cord infarction that occurs when nucleus pulposus material from intervertebral discs spontaneously embolizes into a spinal artery.

Embolism 40

Embolism Inpatient Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP251-AWP251, February 1, 2025. Middle meningeal artery (MMA) embolization is being utilized more frequently as adjunctive and primary treatment. Here, we present the outcomes of this technique with different embolic agents in our patient population.IRB approval was obtained for this study.

Embolism 40

Embolism Strokes Stroke Outcomes 40

Journal of the American Heart Association

MARCH 21, 2025

BackgroundWe aimed to reevaluate randomized controlled trial data on outcomes of cerebral embolic protection device use during transcatheter aortic valve implantation. Primary outcomes included all stroke, disabling stroke, and allcause mortality.

Aortic valve 40

Aortic valve Embolism Aortic Strokes 40

Frontiers in Cardiovascular Medicine

MAY 19, 2024

Although generally considered a benign anatomic variant, a PFO may facilitate passage of a thrombus from the venous to arterial circulation, thereby resulting in cryptogenic stroke or systemic embolization.

Strokes 52

Strokes Stroke Embolism Congenital 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThere is increasing literature to support the efficacy of middle meningeal artery (MMA) embolization in the treatment of chronic subdural hematomas (cSDH). Techniques for optimal embolization of the MMA are yet to be elucidated.

Embolism 40

Embolism Strokes Stroke 40

American College of Cardiology

FEBRUARY 23, 2024

What is the incidence of the embolic and bleeding complications in relation to pre- and post- periprocedure antithrombotic regimens in patients undergoing ventricular arrhythmia radiofrequency ablation (RFA)?

Arrhythmia 61

Arrhythmia Ablation Embolism Strokes 61

American College of Cardiology

OCTOBER 29, 2024

The goal of the PROTECTED TAVR trial was to evaluate the efficacy of intraprocedural cerebral embolic protection (CEP) in reducing strokes among patients undergoing transfemoral TAVR for aortic stenosis.

Aortic valve 42

Aortic valve Aortic TAVR Strokes 42

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP324-ATP324, February 1, 2025. Background and Purpose:Antiphospholipid antibody syndrome (APS) is a rare cause of cerebral infarction, but the effect of antiphospholipid antibodies (aPL) on the acute phase of ischemic stroke in each stroke subtypes is still unclear, especially in the elderly patients.

Embolism 40

Embolism Strokes Stroke Hemorrhage 40