Remove Embolism Remove Outcomes Remove Stroke
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Embolic risk management in infective endocarditis: predicting the 'embolic roulette

Open Heart

Life-threatening complications of infective endocarditis (IE,) are heart failure, uncontrolled infection and embolic events (EE), which pose significant morbidity and mortality risks. Depending on the location and severity of the embolism, the embolic risk can either escalate or alternatively, complicate and delay cardiac surgery.

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Cerebral Embolic Protection by Geographic Region

JAMA Cardiology

This randomized clinical trial evaluates regional differences in the association between stroke outcomes and cerebral embolic protection.

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Abelacimab Stops Bleeding, But Stroke Impact Uncertain

CardiacWire

Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. vs. 0.4%) and 4X ischemic stroke rates (csHR = 4.06). year follow-up. per 100 person-year.

Strokes 59
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OCEANIC-AF: Asundexian Nearly Quadruples Stroke, Embolism Risk vs Apixaban

HCPLive

Asundexian failed to prove noninferiority to apixaban for its primary efficacy outcome in the phase 3 OCEANIC-AF trial.

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Stroke reduction by cerebral embolic protection devices in transcatheter aortic valve implantation: a systematic review and Bayesian meta-analysis

Heart BMJ

Objectives The use of cerebral embolic protection (CEP) during transcatheter aortic valve implantation (TAVI) has been studied in several randomised trials. We aimed to perform a systematic review and Bayesian meta-analysis of randomised CEP trials, focusing on a clinically relevant reduction in disabling stroke.

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Abstract TP388: Integrating standard-of-care clinical stroke workup within in silico embolic stroke models for etiology disambiguation

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP388-ATP388, February 1, 2025. Introduction:Embolic Stroke of Undetermined Source (ESUS) accounts for a critical proportion of all ischemic strokes. Disambiguating embolism etiology is important to improve treatment efficacy and reduce recurrent events.

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Current status of ECMO for massive pulmonary embolism

Frontiers in Cardiovascular Medicine

Massive pulmonary embolism (MPE) carries significant 30-day mortality and is characterized by acute right ventricular failure, hypotension, and hypoxia, leading to cardiovascular collapse and cardiac arrest. Considerable heterogeneity in studies is a significant weakness of the available literature.