Circulation: Cardiovascular Interventions

JANUARY 24, 2024

BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations.

Embolism 75

Embolism Thrombolysis Ultrasound Pulmonary 75

Frontiers in Cardiovascular Medicine

JULY 1, 2024

Notably, acute massive pulmonary embolism (PE) with bilateral atrial thrombosis is an exceptional occurrence in CAPS. Acute pulmonary embolism (PE) is a common cardiovascular disease that progresses rapidly and has a high mortality rate. It primarily affects small vessels, seldom impacting large vessels.

Thrombosis 52

Thrombosis Embolism Pulmonary Laboratory 52

The American Journal of Cardiology

OCTOBER 29, 2024

Publication date: Available online 28 October 2024 Source: The American Journal of Cardiology Author(s): Aryan Mehta, Mridul Bansal, Siddhant Passey, Saurabh Joshi, Carlos L Alviar, Jason N Katz, J Dawn Abbott, Saraschandra Vallabhajosyula

Embolism 40

Embolism Pulmonary Outcomes 40

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure.

Pulmonary 52

Pulmonary Hypertension Angioplasty Pharmacology 52

JAMA Cardiology

NOVEMBER 21, 2023

This cohort study assesses outcomes in patients with pulmonary embolism using high-sensitivity vs conventional troponin I.

Embolism 40

Embolism Pulmonary Outcomes 40

ECG Cases

NOVEMBER 6, 2018

This Best Case Ever elucidates the practical challenges of working up pregnant patients in the ED with a suspicion of pulmonary embolism. Since this recording, the first ever multi-center prospective outcome study looking at the pulmonary embolism workup in pregnancy was published in the Annals of Internal Medicine.

Embolism 52

Embolism Pulmonary Outcomes Ultrasound 52

Journal of Cardiovascular Electrophysiology

MARCH 6, 2024

This novel cryoballoon with adjustable size and low compliance successfully achieves pulmonary vein isolation to treat paroxysmal atrial fibrillation (PAF), providing more options for patients with PAF. Procedural outcomes were defined based on the 2017 HRS consensus statement. Follow-up was performed at 7 days, 3, 6, and 12 months.

Pulmonary 40

Pulmonary Atrial Fibrillation Outcomes Document 40

Circulation: Cardiovascular Interventions

FEBRUARY 27, 2024

In this study, we assessed the clinical predictors and outcomes of advanced therapy compared with anticoagulation alone for the acute management of right heart thrombus.Methods:In this observational cohort study, we analyzed consecutive patients who were treated for right heart thrombus. The primary end point was 90-day all-cause mortality.

Outcomes 40

Outcomes Thrombolysis Embolism Pulmonary 40

American College of Cardiology

APRIL 16, 2024

What are the in-hospital and readmission outcomes in patients with intermediate-risk or high-risk pulmonary embolism (PE) treated with versus without catheter-based therapies (CBTs) in a large retrospective registry?

Embolism 54

Embolism Pulmonary Hospital Outcomes 54

Journal of the American Heart Association

NOVEMBER 28, 2023

Although the clinical outcomes and economic burdens of VTE have been well described, the impact of VTE on patients' health status has yet to be summarized. After screening and exclusion, 136 references were identified; 5 described PROM development, 20 focused on PROM validation, and 111 used PROMs in outcomes research.

Quality of Life 40

Quality of Life Outcomes Embolism Pulmonary 40

DAIC

NOVEMBER 7, 2024

recently announced new data that demonstrate patients with intermediate-risk pulmonary embolism (PE) treated with Penumbra’s computer assisted vacuum thrombectomy (CAVT) technology have a shorter length of hospital stay, shorter post-procedure length of stay and fewer complications compared to other treatment options.

Hospital 59

Hospital Technology Inpatient Thrombolysis 59

Journal of the American Heart Association

MARCH 8, 2024

A slowly maturing evidence base has suggested that cardiogenic shock teams may improve patient outcomes.

Cardiogenic Shock 40

Cardiogenic Shock Best Practices Outcomes Education 40

Heart BMJ

JULY 25, 2024

We aimed to assess the characteristics and outcomes of SCA according to cancer history. vs 46.8%, p<0.001) and had more respiratory causes (pulmonary embolism and hypoxaemia in 34.2% Still, in-hospital outcomes remain similar even in patients with known cancer. vs 10.8%, p<0.001). vs 29.8%, respectively, p=0.27).

Cardiac Arrest 52

Cardiac Arrest Cancer Hospital Embolism 52

Stroke Journal

FEBRUARY 1, 2024

Our primary study outcome was any stroke or major thrombotic event identified within 60 days of OHSS diagnosis in HCUP or during the index admission for OHSS in NIS. The low rate of outcome events after OHSS seen in each of our population-level analyses increases the reliability of these study results.

Thrombosis 40

Thrombosis Inpatient Embolism Myocardial Infarction 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

This study aims to investigate the incidence, complications, and outcomes of SAH patients who develop HIT.MethodsICD‐9‐CM and ICD‐10‐CM codes were used to query the National Inpatient Sample for patients with SAH between 2010 and 2019. Patients with SAH are an understudied population in terms of assessing incidence and impact of HIT.

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Thrombosis 40

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

In the light of increasing availability, the analyses of outcome-relevant predisposing characteristics are of growing importance. The primary outcome was defined as the survival of patients until they were discharged from the hospital, with a favourable neurological outcome [cerebral performance category (CPC) score of ≤2].

Cardiogenic Shock 64

Cardiogenic Shock Cardiac Arrest BMI Coronary Artery Disease 64

Open Heart

NOVEMBER 28, 2023

Eligible were all aetiological studies evaluating risk of cardiovascular outcomes after exposure to common RTIs within any follow-up duration. to 10)), pulmonary embolism (24.6 This systematic review and meta-analysis aimed to estimate the causal effects of RTIs on occurrence of cardiovascular diseases in the general population.

Myocardial Infarction 52

Myocardial Infarction COVID-19 Cardiovascular Disease Thrombosis 52

Dr. S. Venkatesan MD

JUNE 17, 2024

The usefulness of JVP in a cardiac emergency like acute pulmonary embolism may appear superfluous. But, the fact of the matter is, a persistently raised JVP with good waveform, without systemic hypotension, may not portend a bad outcome. Please go to the full-screen view and freeze the video to read the text.

Tricuspid 40

Tricuspid Thrombolysis Embolism Pulmonary 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

A prior published analysis of national trends after one year in mechanical thrombectomy use and outcomes for stroke before and after publication of the 2015 US guideline update showed improved functional outcomes and lower peri‐procedural mortality. Safety outcomes include in‐hospital medical complications and mortality.

Stroke 40

Stroke Strokes Cardiac Arrest Inpatient 40

Circulation

NOVEMBER 11, 2023

Results:From 785 unique citations, we identified two randomized trials with relevant clinical outcome data; NOAH-AFNET 6 (2,536 participants) evaluated edoxaban and ARTESiA (4,012 participants) evaluated apixaban. We used random-effects models for meta-analysis and rated the quality of evidence using the GRADE framework.

Atrial Fibrillation 40

Atrial Fibrillation Stroke Strokes Embolism 40

DAIC

MAY 7, 2024

Women and black patients were less frequently treated with minimally invasive therapy compared to men or non-Black patients, according to new data from the REAL-PE analysis which investigated catheter-based pulmonary embolism (PE) treatment. Late-breaking results from the study, for which Sahil A.

Embolism 122

Embolism Pulmonary Blood Clot Interventional Cardiology 122

EMS 12-Lead

MARCH 30, 2024

The receiving staff suspects pulmonary embolism due to S1Q3T3 on the ECG and administers TPA. The patient did have massive pulmonary emboli, but he also had profound intraventricular and subarachnoid hemorrhages. The patient was ultimately discharged with a poor neurologic outcome. On ED arrival ROSC is achieved.

Cardiac Arrest 124

Cardiac Arrest Pacemaker Pulmonary Bradycardia 124

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Further research and attention to this area are crucial for improving patient outcomes and guiding clinical interventions in this challenging condition.MethodsICD‐10‐CM codes were used to query the National Inpatient Sample (NIS) for patients with AIS between 2010 and 2019.

Hemorrhage 40

Hemorrhage Aneurysm Cardiac Arrest Myocardial Infarction 40

Dr. Smith's ECG Blog

OCTOBER 27, 2024

No pulmonary embolism is identified. A paradox in the literature: All trials of very early intervention for NSTEMI which do not exclude patients with persistent chest pain show that intervention in < 2 hours results in a better outcome. CT Angio Chest IMPRESSION 1. No thoracic aortic hematoma, aneurysm or dissection.

STEMI 119

STEMI Chest Pain Myocardial Infarction Aneurysm 119

Dr. Smith's ECG Blog

NOVEMBER 25, 2017

Peak troponin, echocardiographic findings, and long term outcome are unknown. A new right bundle branch block in a sick patient with chest pain and/or shortness of breath is a worrisome finding concerning for LAD occlusion or significant pulmonary embolism. Learning Points: 1.

Chest Pain 52

Chest Pain Pericarditis Embolism Stents 52

Stroke Journal

FEBRUARY 1, 2024

Our study aimed to compare outcomes of patients diagnosed with CVT within 2 weeks of COVID infection compared to those without COVID-19.Methods:Adult All-cause mortality was the primary outcome. Stroke, Volume 55, Issue Suppl_1 , Page AWMP49-AWMP49, February 1, 2024. vs 13.6%; HR=1.51; 95% CI=1.04-2.20) 2.20) but not at three months.

COVID-19 40

COVID-19 Outcomes Thrombosis Embolism 40

Dr. Smith's ECG Blog

JANUARY 9, 2023

CT angiogram chest: no aortic dissection or pulmonary embolism. Serial chest xrays: progressive bilateral pulmonary edema. Smith Major Learning Point: The worst risk factor for a bad outcome in OMI is young age because cardiologists cannot believe that a young person can have an OMI. No further troponins were measured.

Chest Pain 52

Chest Pain Aneurysm STEMI Thrombosis 52

Dr. Smith's ECG Blog

JANUARY 12, 2023

CT pulmonary angiogram was negative for pulmonary embolism. Learning Points It takes dedicated learning and observation of outcomes and serial ECGs to learn how to distinguish subtle OMI patterns from OMI mimics like the cases above. Second troponin T resulted at 1,318 ng/L. Chest x-ray was read as normal. Reocclusion!

Chest Pain 52

Chest Pain STEMI Blog Stenosis 52

Dr. Smith's ECG Blog

NOVEMBER 12, 2020

and the patient was converted to veno-venous (V-V) ECMO due to persistent pulmonary insufficiency. However, in multiple studies, even in the absence of AMI, both acute and chronic myocardial injury (as diagnosed by any elevated cTn) are powerful markers of adverse outcomes in both the short and long term. 3–8 Shi et al.

Cardiac Arrest 52

Cardiac Arrest COVID-19 Myocardial Infarction Cardiogenic Shock 52

Stroke Journal

FEBRUARY 1, 2024

Prolonged ICU LoS is reported to be associated with worse clinical outcomes, but factors associated with prolonged LoS after MT are not established.Methods:A retrospective analysis of 499 patients undergoing EVT at a single large comprehensive stroke center from January 2015 to May 2020 was performed. P&lt;0.001). ASPECTS &lt; 7 (6.9

ICU 40

ICU Stroke Strokes Embolism 40

Dr. Smith's ECG Blog

JANUARY 17, 2024

. = Application of the above ECG Mantras: Given the presentation of new-onset CP for both patients in today's Blog post — time-efficiency for determining the need for prompt cath is essential for optimal outcome. = Are there 1 or 2 Leads that give you the answer? But ECG #1 is not "normal".

Chest Pain 104

Chest Pain STEMI Myocardial Infarction Blog 104

Dr. Smith's ECG Blog

APRIL 8, 2015

Cardiac Syncope ("True Syncope") Independent Predictors of Adverse Outcomes condensed from multiple studies 1. These premonitory symptoms were negative predictors of adverse outcomes in EGSYS. Aortic Dissection, Valvular (especially Aortic Stenosis), Tamponade. Abnormal ECG – looks for cardiac syncope. Syncope with Exertion (EGSYS) 7.

Arrhythmia 52

Arrhythmia Outcomes Risk Factors Chest Pain 52