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Study Shows Abelacimab Significantly Reduced Bleeding vs. Standard DOAC

DAIC

This underuse of anticoagulants for stroke prevention has been cited as one of the greatest public health issues facing cardiovascular patients 6. Many doctors are put in the unfortunate position of having to weigh the risk of stroke against the risk of bleeding for their patients with AFib, said Christian T.

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Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

DAIC

Ruff, MD, MPH, senior investigator of TIMI Group, director General Cardiology, Brigham and Women's Hospital, and associate professor, Harvard Medical School. There is a need for safer anticoagulants that can prevent thrombotic events while minimizing excess bleeding, said Christian T.

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ARCADIA Trial on Atrial Cardiopathy and Stroke

All About Cardiovascular System and Disorders

In an earlier post on Embolic Stroke of Undetermined Source (ESUS) , I had mentioned about ARCADIA trial (AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke) which was testing whether there is role for apixaban compared to aspirin for prevention of recurrent stroke in ESUS. 2023.27188.

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Hypertrophic Cardiomyopathy

All About Cardiovascular System and Disorders

SAM causes LVOTO, increased ejection time and a decreased stroke volume, as well as mitral regurgitation due to poor coaptation of the leaflets. Mid cavity obstruction in HCM is associated with apical aneurysm, systemic embolism, and arrhythmias. Echocardiogram showing thickened interventricular septum and mitral regurgitation in HCM.

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Link Between Clonal Hematopoiesis and Stroke in Carotid Stenosis

All About Cardiovascular System and Disorders

About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke.

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Potential Risk of Serious Bleeding in Patients With AF Using Diltiazem With Apixaban or Rivaroxaban

All About Cardiovascular System and Disorders

Ischemic stroke, systemic embolism, intracranial or fatal extracranial bleeding and death with recent evidence of bleeding were the secondary outcomes evaluated. It was a retrospective cohort study which included US Medicare benefiaries aged 65 years or more with atrial fibrillation and follow up period was one year.