Dr. Smith's ECG Blog

JANUARY 9, 2024

Slow VT below the detection rate of the ICD lead to worsening heart failure and low stroke volume. Post conversion of VT the patient had low output cardiac failure and became unstable and hypoperfused. Cardiac output (CO) was being maintained by the tachycardia. After atrial rhythm/SR was restored the patient slowly improved.

Tachycardia 119

Tachycardia Electrophysiology Atrial Flutter Ischemia 119

Frontiers in Cardiovascular Medicine

FEBRUARY 21, 2024

Background The use of SGLT-2 inhibitors has revolutionized heart failure therapy. In the presence of pinacidil induced arrhythmogenicity, neither SGLT2 inhibitor had a significant impact on cardiac electrophysiology. Conclusion In this model, empagliflozin and dapagliflozin demonstrated opposite antiarrhythmic properties.

Electrophysiology 59

Electrophysiology Atrial Fibrillation Arrhythmia Cardiac Function 59

HeartRhythm

JULY 9, 2024

Cardiac electrophysiologic and Cardiovascular involvement has long been important in the surveillance, care, and prognosis of patients with both BMD and DMD, and is the leading cause of mortality in patients with DMD.

Electrophysiology 40

Electrophysiology Heart Failure Cardiomyopathy 40

Journal of Cardiovascular Electrophysiology

JANUARY 17, 2025

ABSTRACT Atrial flutter (AFL), defined as macro-re-entrant atrial tachycardia, is associated with debilitating symptoms, stroke, heart failure, and increased mortality. Atypical AFL is a heterogenous group of re-entrant atrial tachycardias that most commonly occur in patients with prior heart surgery or catheter ablation.

Atrial Flutter 40

Atrial Flutter Electrophysiology Ablation Tachycardia 40

HeartRhythm

SEPTEMBER 25, 2023

In heart failure with reduced ejection fraction and heart failure with preserved ejection fraction, profound cellular and molecular changes have recently been documented in the failing myocardium.These changes include altered calcium handling and metabolic efficiency of the cardiac myocyte, reactivation of the fetal gene program, changes in the electrophysiological (..)

Preserved Ejection Fraction 40

Preserved Ejection Fraction Electrophysiology Heart Failure Document 40

American College of Cardiology

APRIL 24, 2024

The PRO portion of the currently featured PRO/CON debate between Dr. Brian Olshansky and Dr. John Mandrola presents a significant conundrum within the fields of electrophysiology and geriatric cardiology.

Atrial Fibrillation 56

Atrial Fibrillation Heart Failure Electrophysiology Ablation 56

DAIC

MARCH 27, 2025

1,2 People living with AFib face an increased risk of stroke, heart failure and death, and many rely on cardiac ablation to treat the condition effectively. chief medical officer of Abbott's electrophysiology business. Gian-Battista Chierchia at the University of Brussels in Belgium; and Prof.

Ablation 52

Ablation AFIB Atrial Fibrillation Electrophysiology 52

Circulation

JANUARY 8, 2024

BACKGROUND:The relationship between heart failure (HF) and atrial fibrillation (AF) is clear, with up to half of patients with HF progressing to AF. Circulation, Ahead of Print. The pathophysiological basis of AF in the context of HF is presumed to result from atrial remodeling.

Atrial Fibrillation 45

Atrial Fibrillation Heart Failure Electrophysiology Arrhythmia 45

Journal of the American Heart Association

FEBRUARY 14, 2025

The overexpression of Cav1 reset the influence of vagotomy.ConclusionsWe found that LIPUS had a direct effect on regional antiinflammation and antifibrosis, improved cardiac autonomic function and heart failure, protected the Cx43 (connexin43) protein, and reduced the risk of malignant arrhythmia during ICM.

Electrophysiology 45

Electrophysiology Ultrasound Cardiomyopathy Arrhythmia 45

HeartRhythm

SEPTEMBER 4, 2023

Myocardial calcium (Ca2+) signaling plays a crucial role in contractile function and membrane electrophysiology. An abnormal myocardial Ca2+ transient is linked to heart failure and ventricular arrhythmias.

Heart Failure 40

Heart Failure Arrhythmia Electrophysiology Cardiomyopathy 40

Cardiology Update

JANUARY 2, 2024

Heart Failure 2024 Date: May 11-14, 2024 Location: Lisbon, Portugal and online Overview: The Heart Failure Congress stands as the premier global gathering encompassing the full spectrum of heart failure. Hashtag: #ESCPrev2024 5. Hashtag: #HeartFailure2024 6.

Heart Failure 111

Heart Failure Atherosclerosis Cardiovascular Imaging Non-Invasive Cardiology 111

HeartRhythm

APRIL 28, 2024

Left bundle branch (LBB) area pacing (LBBAP) has become a cardiac resynchronization therapy (CRT) modality in patients with heart failure (HF) and LBB block (LBBB). However, the electrophysiological differences between LBBP and LVSP and the methods to differentiate LBBP from LVSP in patients with HF and LBBB need investigations.

Heart Failure 40

Heart Failure Electrophysiology 40

Frontiers in Cardiovascular Medicine

JANUARY 16, 2024

This study aimed to assess the electrophysiological characteristics of atrial fibrillation patients with dilated cardiomyopathy and compare the long-term clinical outcomes between patients undergoing catheter ablation and medical therapy.

Atrial Fibrillation 64

Atrial Fibrillation Ablation Cardiomyopathy Heart Failure 64

Circulation: Heart Failure

JANUARY 28, 2025

Circulation: Heart Failure, Ahead of Print. BACKGROUND:The therapeutic armamentarium for heart failure with preserved ejection fraction (HFpEF) remains notably constrained.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Obesity Diabetes 40

American College of Cardiology

APRIL 24, 2024

Brian Olshansky and John Mandrola currently featured presents a conundrum within the fields of electrophysiology and geriatric cardiology. The CON portion of the PRO/CON debate between Drs.

Atrial Fibrillation 46

Atrial Fibrillation Heart Failure Electrophysiology Ablation 46

DAIC

JUNE 11, 2024

Patients suffering from heart rhythm disorders are now being successfully treated with robotic ablation procedures using this advanced technology, and Hospital Santa Maria della Pietà is the first hospital in Italy to adopt the cutting-edge Genesis Robotic Magnetic Navigation (RMN) system. “As

Heart Rhythm 81

Heart Rhythm Technology Electrophysiology Arrhythmia 81

DAIC

JULY 31, 2024

This potential vascular market for this product family is measured in millions of procedures per year, including cardiac interventions such as structural heart procedures and electrophysiology procedures, peripheral vascular interventions including renal interventions, endovascular aortic repair, and carotid artery interventions.

Myocardial Infarction 99

Myocardial Infarction Technology Angina Pulmonary 99

DAIC

MARCH 8, 2024

suffer from heart failure , and there are approximately 400,000 heart-failure-related deaths in this country each year. Patients with heart failure often experience reduced mobility, quality of life and ability to work; the disease also represents a significant public health care burden.

Blood Clot 98

Blood Clot Heart Failure Quality of Life Innovation 98

Circulation: Arrhythmia and Electrophysiology

JUNE 15, 2021

Circulation: Arrhythmia and Electrophysiology, Ahead of Print.

Heart Failure 40

Heart Failure Electrophysiology Arrhythmia Circulation 40

Circulation: Arrhythmia and Electrophysiology

OCTOBER 22, 2024

Circulation: Arrhythmia and Electrophysiology, Ahead of Print.

Atrial Fibrillation 40

Atrial Fibrillation Electrophysiology Heart Failure Exercise 40

Journal of Cardiovascular Electrophysiology

AUGUST 7, 2023

Abstract A vast amount of now well-established clinical and epidemiological data indicates a close, interdependent, and symbiotic association between atrial fibrillation (AF) and heart failure (HF). Both AF and HF, when co-exist in a patient, have serious treatment and prognostic implications.

Atrial Fibrillation 40

Atrial Fibrillation Heart Failure Ablation Outcomes 40

American College of Cardiology

APRIL 24, 2024

He also has New York Heart Association (NYHA) class II heart failure with reduced ejection fraction and left ventricular ejection fraction (LVEF) 40%. PT is an 82-year-old man who presents with persistent, mildly symptomatic atrial fibrillation (AF) of approximately 4-5 months' duration.

Atrial Fibrillation 40

Atrial Fibrillation Electrophysiology Heart Failure Ablation 40

DAIC

DECEMBER 27, 2023

The robotic technology represented an entirely novel way to address heart rhythm disorders in a minimally invasive procedure with the benefits of robotic precision and safety. When left untreated, arrhythmias may significantly increase the risk of stroke, heart failure, and sudden cardiac arrest.

Technology 105

Technology Heart Disease Heart Rhythm Arrhythmia 105

Journal of Cardiovascular Electrophysiology

NOVEMBER 7, 2024

Central illustration: In this study comparing left bundle branch area pacing (LBBAP) versus endocardial resynchronization (Endo-CRT), both strategies were associated with a similar incidence of the composite outcome of heart failure-related hospitalization and all-cause mortality.

Heart Failure 40

Heart Failure Hospital Outcomes Stroke 40

Journal of Cardiovascular Electrophysiology

DECEMBER 15, 2023

Impact of preceding systolic heart failure on risk of pacemaker-induced cardiomyopathy Abstract Background Pacemaker-induced cardiomyopathy is a well described phenomenon in patients with preserved ejection fraction at the time of permanent pacemaker implant.

Heart Failure 40

Heart Failure Preserved Ejection Fraction Pacemaker Cardiomyopathy 40

DAIC

JULY 24, 2024

Volta Medical has announced it has entered into a Joint Development Agreement with GE Healthcare to enhance arrhythmia procedures with artificial intelligence (AI)-driven electrophysiology technologies. Our mission to combat complex heart rhythm diseases relies on optimizing interoperability.

Atrial Fibrillation 105

Atrial Fibrillation AFIB Ablation Technology 105

Journal of Cardiovascular Electrophysiology

NOVEMBER 26, 2024

ABSTRACT Introduction Atrial fibrillation (AF) can cause or aggravate heart failure (HF). Catheter ablation (CA) is an effective treatment for AF. This study focused on the feasibility and outcomes of emergent AF ablation performed during hospitalization for acute HF.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Heart Failure Hospital 40

Journal of Cardiovascular Electrophysiology

MARCH 3, 2025

ABSTRACT Background Atrial fibrillation (AF) recurrence remains a significant challenge in heart failure with reduced ejection fraction (HFrEF) patients undergoing cryoballoon ablation (CBA). Secondary endpoints included all-cause mortality and heart failure (HF)-related hospitalizations. vs. 39.4%, p =0.036).

Atrial Fibrillation 40

Atrial Fibrillation Heart Failure Ablation Outcomes 40

Circulation

APRIL 1, 2025

BACKGROUND:Gene mutations are responsible for a sizeable proportion of cases of heart failure. Circulation, Ahead of Print. However, the number of patients with any specific mutation is small.

Electrophysiology 45

Electrophysiology Heart Failure Cardiomyopathy Circulation 45

Journal of Cardiovascular Electrophysiology

OCTOBER 21, 2024

Abstract Introduction Catheter ablation for atrial fibrillation (AF) reduces heart failure (HF) hospitalization in patients with HF with preserved ejection fraction (HFpEF). However, the long-term outcomes and subclinical HF after nonparoxysmal AF ablation in HFpEF patients have not been fully evaluated.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 40

HeartRhythm

JUNE 4, 2024

Diabetes mellitus induces adverse structural, electrophysiological, and autonomic cardiac remodeling which can increase one’s risk of ventricular arrhythmias and SCD. In this narrative review, we describe the contribution of DM to the pathophysiology of SCD beyond its role in atherosclerotic cardiovascular disease and heart failure.

Sudden Cardiac Death 40

Sudden Cardiac Death Arrhythmia Diabetes Electrophysiology 40

Journal of Cardiovascular Electrophysiology

DECEMBER 17, 2024

Abstract Background Heart failure (HF) with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) are associated with high morbidity and mortality. Recently, sinus rhythm (SR) maintenance (SRM) after catheter ablation (CA) of AF (AFCA) in HFpEF has shown to reduce adverse events as compared to medical treatment.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Atrial Fibrillation Heart Failure Ablation 40

DAIC

APRIL 9, 2024

It is also published in Heart Rhythm , the official journal of the HRS, Journal of Arrhythmia , the official journal of the APHRS, and Journal of Interventional Cardiac Electrophysiology , the official journal of the LAHRS. 7 Atrial fibrillation has a significant impact on people’s lives.

Atrial Fibrillation 105

Atrial Fibrillation Ablation Heart Rhythm Blood Clot 105

DAIC

DECEMBER 29, 2023

Early treatment of persistent AF can reduce the risk of blood clots, stroke, and heart failure, and may prevent the disease from becoming permanent. Patients are often treated with AADs as frontline therapy for heart rhythm maintenance, though some can experience adverse effects and limited efficacy.

Atrial Fibrillation 115

Atrial Fibrillation Ablation Atrial Flutter Blood Clot 115

HeartRhythm

SEPTEMBER 8, 2023

Atrial fibrillation (AF) stands as the most prevalent cardiovascular disease, posing significant risks of stroke, heart failure (HF), and other complications that contribute to morbidity and mortality.

Atrial Fibrillation 40

Atrial Fibrillation Electrophysiology Heart Failure Cardiovascular Disease 40

DAIC

DECEMBER 14, 2023

It's a major step towards fulfilling our vision of providing disruptive electrophysiology solutions for patients," said Rebecca Seidel, SVP and President of the Cardiac Ablation Solutions business, which is part of the Cardiovascular Portfolio. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study.

Atrial Fibrillation 105

Atrial Fibrillation Ablation Technology Heart Failure 105

HeartRhythm

OCTOBER 18, 2023

In addition to these electrophysiological and reversible changes, which occur relatively early during AF, AF has been shown to be also associated with cardiac structural alterations including atrial dilatation and the development of heart failure (2).

Atrial Fibrillation 40

Atrial Fibrillation Electrophysiology Heart Failure 40