Dr. Paddy Barrett
NOVEMBER 8, 2024
Let’s start with the fact that this is not a yes or no answer. To answer this question, you need to understand three key factors: What is your baseline risk? Over what time horizon are you looking to reduce risk? What is your attitude toward reducing that risk? Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol.
Dr. Smith's ECG Blog
NOVEMBER 27, 2024
Pendell and I and the geniuses at Powerful Medical (Producers of the PMCardio Queen of Hearts OMI AI app ) are working on an objective, mathematical definition of hyperacute T-waves , based on real OMI outcomes and hyperacute T-wave annotation that has excellent interrater agreement (between me and Pendell), and it will end up being a logistic regression using these 3 variables: 1) area under the curve (AUC) relative to the QRS size 2) increased symmetry , as defined by time from T-wave onset to
Science Daily - Stroke
DECEMBER 18, 2024
Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.
Science Daily - Heart Disease
DECEMBER 2, 2024
Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study. According to the researchers, these risk reductions are likely driven by the replacement of red and processed meats with plant proteins. The researchers also observed that a combination of consuming more plant protein and higher protein intake overall provided the most heart health benefits.
CardiacWire
OCTOBER 30, 2024
We’re dedicating today’s top story to the people and publications that we rely on to find the most interesting cardiology stories from across the web. Assuming that you already subscribe to Cardiac Wire , these are the 40 other newsletters, websites, and social media stars to follow if you want to keep up with the latest and greatest in cardiology. I’ll always check the mainstream cardiology news websites ( TCTMD , Medscape , et al.) and the major cardiovascular journals ( JACC , AHA , JAMA Card
Medical Xpress - Cardiology
NOVEMBER 14, 2024
Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens.
Frontiers in Cardiovascular Medicine
NOVEMBER 17, 2024
IntroductionA direct causal link between Sudden Cardiac Death (SCD) and COVID-19 is unproven, although current data suggest a plausible association.AimThis study aims to map and analyze the intersection of research on sudden cardiac death and COVID-19 through a comprehensive bibliometric analysis.MethodologyThis study searched the literature by applying the keywords “COVID-19” AND “Sudden Cardiac Death (SCD)”.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
DAIC
NOVEMBER 18, 2024
tim.hodson Mon, 11/18/2024 - 10:55 Nov. 16, 2024 Anthos Therapeutics, Inc.recently presented new data at the American Heart Association (AHA) Scientific Sessions from its AZALEA-TIMI 71 study that demonstrated the novel factor XI inhibitor abelacimab led to consistent and substantial reductions in bleeding for patients on or off antiplatelet (APT) therapy, as compared to rivaroxaban.
Heart BMJ
OCTOBER 28, 2024
Background Cardiology training is demanding and associated with high workloads. Poor lifestyle and health among clinicians may stretch workforces and impact patient care. It has not been established what impact training in cardiology has on the doctors undertaking it. We aimed to establish the prevalence of physical and mental illness, burnout and the ability to maintain a healthy lifestyle among cardiology trainees in the United Kingdom (UK).
Dr. Malcolm Kendrick
DECEMBER 5, 2024
And so, we reach the final end to the court case. You may think it all finished months ago, not so. The final, final act is when we have the reading of the Statement in Open Court (SIOC). This took place Thursday the 5 th of December 2024. Which is five years and nine months after the articles in the Mail on Sunday were published. I could not talk or write about the SIOC before it happened, or the Judge would be most upset and angry.
Dr. Paddy Barrett
NOVEMBER 1, 2024
“But what can I do to make a difference?” This is one of the most common questions I get as a cardiologist when talking about preventing heart disease and living longer. As a doctor, there are many things I can do, and only a doctor can do: Prescribe medications Order certain diagnostic tests. Perform or arrange medical procedures. And so on.
Ken Grauer, MD
MARCH 1, 2024
I was sent the 2 ECGs shown in Figure-1 — which were recorded from an elderly man whose heart beat "has been irregular for years". No clear history for recent chest pain — but the patient "has not been well" for the previous week. Regarding the 2 ECGs in Figure-1 : ECG #1 is the initial tracing obtained at the scene by the EMS ( E mergency M edical S ystems ) team — in association with an alert but markedly hypotensive patient.
HeartRhythm
DECEMBER 31, 2024
Curtain etal1 performed an analysis of the VALIANT (Valsartan in Acute Myocardial Infarction) and PARADISE-MI (Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI) trials to evaluate whether risk of sudden cardiac arrest (SCA) following acute myocardial infarction (MI) has changed over time. Patients recruited to these trials had left ventricular ejection fraction (LVEF) <40% following acute MI.
Science Daily - Heart Disease
NOVEMBER 6, 2024
New collaborative research has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US. The study looked at the efficacy of different low-cost cooling strategies -- such as electric fans with and without spraying water on the skin -- for older adults, who are known to be at a heightened health risk during hot summer weather.
CardiacWire
DECEMBER 6, 2024
Topline results from the SURMOUNT-5 trial found Eli Lillys tirzepatide led to far greater weight loss than Novo Nordisks semaglutide, giving Lilly a boost in the race to become Americas go-to GLP-1. Semaglutide and tirzepatide both originally received FDA approval for treating adults with T2D, with those approvals later extending to weight loss management.
Medical Xpress - Cardiology
NOVEMBER 21, 2024
After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart. This is according to a new study from Karolinska Institutet published in the journal Circulation.
Circulation
DECEMBER 3, 2024
Circulation, Ahead of Print. Smokeless oral nicotine products are addictive, and their use has potential adverse effects on some but not all biomarkers of cardiovascular risk. The use of some types of these products, for instance, is associated with an increased mortality risk in those with ischemic heart or cerebrovascular disease. Similarly, smokeless tobacco has the potential to increase the risk of oral cancer, but the risks depend on the chemical composition of the product.
Frontiers in Cardiovascular Medicine
NOVEMBER 14, 2024
BackgroundIn recent years, the relationship between periodontal disease (PD) and atherosclerosis (AS) has garnered significant scholarly attention. Chronic inflammation induced by PD may promote the onset and progression of AS through multiple mechanisms. Given the increasing global incidence of both PD and AS, which adversely affects patients’ quality of life and longevity, further investigation into the interplay between PD and AS is of substantial clinical importance.
Nature Reviews - Cardiology
NOVEMBER 18, 2024
Nature Reviews Cardiology, Published online: 19 November 2024; doi:10.1038/s41569-024-01105-y Large language models represent a transformative leap in artificial intelligence and natural language processing, offering exciting potential across cardiology, from clinical care to education and research. However, several crucial challenges limit the practical implementation of large language models in cardiology.
DAIC
DECEMBER 3, 2024
tim.hodson Tue, 12/03/2024 - 16:52 Nov. 18, 2024 — In November, Esperion presented an analysis from the CLEAR Outcomes study focused on patients with Peripheral Artery Disease (PAD) who were unable or unwilling to take statin medications. These data were presented at the 2024 American Heart Association Scientific Sessions, in Chicago, IL. Additionally, two exploratory analyses from the CLEAR Outcomes trial and a real-world analysis of bempedoic acid usage were presented at the conference.
The British Journal of Cardiology
NOVEMBER 6, 2024
Cardiovascular disease remains the leading cause of death for women, responsible for over a third of all deaths. 1 In contrast, women remain widely under-represented in cardiovascular trials, 2 as well as in their roles as physicians and trialists. 3 The scarcity of female representation in cardiology carries broad consequences, affecting patient care quality, workplace diversity, and the inclusion of women in clinical trials.
Dr. Paddy Barrett
DECEMBER 27, 2024
I am a little odd. At least, according to my wife, anyway. I love Mondays and January. Everyone else seems to dislike these calendar milestones, but for me, they represent a fresh start and the opportunity to reassess the work that needs to be done. As we approach the end of the year and prepare to set out into the next one, the most common New Year resolutions are often health-related.
Ken Grauer, MD
MARCH 27, 2024
I was sent the ECG in Figure-1 — with the following history: The patient is a young man in his early 20s — who presents to the ED ( E mergency D epartment ) because of SOB ( S hortness O f B reath ) that had been ongoing for several hours. No chest pain. He reports a number of similar previous episodes over the past few years ( although apparently has not been formerly evaluated for this ).
ADN Center of Excellence
NOVEMBER 14, 2024
For medical professionals, the path to excellence is one of continuous learning and skill enhancement. Fellowships represent a vital opportunity to bridge the gap between general practice and advanced specialization. Whether you are at the crossroads of choosing your career focus or seeking to refine your expertise, a fellowship could be the game-changing step you need.
Science Daily - Heart Disease
NOVEMBER 18, 2024
A study testing a new nasal spray form of the medication bumetanide, a commonly prescribed diuretic, was found to be as safe and well-tolerated (meaning with no significant nasal irritation) in healthy adults in comparison to the oral and intravenous forms of the medication. The existing oral and intravenous forms of bumetanide are commonly prescribed for people with heart failure because they ease tissue swelling, a common cause of symptoms for people with heart failure.
CardiacWire
NOVEMBER 8, 2024
Late-breaking second year results from the PROMISE II trial showed that the LimFlow system achieved strong outcomes for avoiding amputations and promoting limb salvage among “no-option” patients with chronic limb-threatening ischemia (CLTI). The LimFlow system consists of several products designed to optimize blood flow in critically ischemic feet by facilitating revascularization.
Medical Xpress - Cardiology
NOVEMBER 14, 2024
A research team from the Nagoya University Graduate School of Medicine has discovered a promising way to slow the progression of heart failure in mice. They fed mice a diet rich in the soybean protein, β-conglycinin (β-CG), which can support heart health by influencing gut bacteria. Their analysis revealed that the soybean protein rich diet increased the production of the short-chain fatty acids (SCFAs) in the intestine that play a role in protecting the heart.
Heart Sisters
DECEMBER 8, 2024
"When Connie Jorsvik was a cardiac nurse, it always seemed like more women than men were admitted to her hospital after Christmas. Many of these women had been experiencing cardiac symptoms for days - and even weeks. Women tend to put off seeking treatment because we so often put ourselves last on our priority list - and there is no bigger time for everyone else's priorities than the holidays!
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundIt's recognized that stress hyperglycemia ratio (SHR) is considered a significant indicator of poor prognosis in many diseases. However, its role in critically ill patients with acute heart failure (acute HF) remains underexplored.MethodsWe conducted a retrospective cohort study on patients with acute HF included in the Medical Information Mart for Intensive Care IV (MIMIC-IV) version 2.2 database.
MIBHS
DECEMBER 27, 2024
Heart bypass surgery, formally known as coronary artery bypass graft (CABG) surgery, is a life-saving procedure that helps improve blood flow to the heart when coronary arteries become blocked or narrowed. This surgery involves creating new pathways for blood to flow to the heart muscle by bypassing the blocked sections of the arteries. While this procedure can significantly enhance heart function and reduce symptoms of heart disease, it does come with potential risks and complications.
Physiologically Speaking
DECEMBER 2, 2024
Greetings! In case you missed it, here are all of the studies I covered in the November 2024 installments of the Physiology Friday newsletter. Enjoy (or re-enjoy) these summaries, and don’t forget to share them with someone you think might learn from or be interested in them. Thanks for reading! Physiologically Speaking is a reader-supported publication.
DAIC
NOVEMBER 25, 2024
tim.hodson Mon, 11/25/2024 - 18:06 Nov. 22, 2024 — BridgeBio Pharma, Inc. recently announced that the U.S. Food and Drug Administration (FDA) approved Attruby (acoramidis), an orally-administered near-complete (≥90%) stabilizer of Transthyretin (TTR) for the treatment of adults with ATTR-CM to reduce cardiovascular death and cardiovascular-related hospitalization.
Dr. Paddy Barrett
NOVEMBER 15, 2024
Being overweight is a major risk factor for heart disease and also an early death. But even if you have excess weight, there are many things you can do to seriously reduce that risk without focusing on weight loss itself. So, if you struggle with excess weight, you need to know what else you can do to reduce your future risk. The Life Essential 8 are a set of factors that significantly influence your risk of heart disease and early death, including: Regular Physical Activity.
Ken Grauer, MD
OCTOBER 10, 2024
I was sent the ECG shown in Figure-1 — told only that the patient was a middle-aged man with septicemia. QUESTIONS: Is this rhythm too fast to be sinus tachycardia? Are flutter waves hidden within the QRS and T waves? Are we seeing the retrograde P waves of AVNRT? Is this ATach ( A trial T achycardia )? Figure-1: The initial ECG in today's case. MY Thoughts on Today’s CASE: In my opinion — none of the above answers are optimal to describe the rhythm in Figure-1.
ADN Center of Excellence
NOVEMBER 7, 2024
The journey from a freshly minted medical graduate to a skilled specialist involves years of dedication, hard work, and targeted training. Among the pivotal steps in this journey, fellowship programs play an essential role in helping doctors gain hands-on experience, deepen their expertise, and establish a career path in highly specialized fields. At ADN CoE, we are dedicated to providing top-tier fellowship programs in various specialties, enabling medical professionals to excel in their chosen
Science Daily - Heart Disease
NOVEMBER 26, 2024
You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders -- strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in one gender over the other, especially as it relates to the heart.
CardiacWire
NOVEMBER 13, 2024
Troubling results from the SAFE-IVC study revealed that just one in six patients gets their inferior vena cava filters removed, despite clear guidelines calling for IVC filter removal as early as possible. An IVC filter is a small device that helps stop blood clots from going up into the lungs and is usually surgically inserted. IVC filters are used to prevent pulmonary embolism in patients with venous thromboembolism and can’t receive anticoagulation treatment.
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