2024

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ECG Blog #419 — The Cause of ECG #1?

Ken Grauer, MD

I was sent the 2 ECGs shown in Figure-1 — which were recorded from an elderly man whose heart beat "has been irregular for years". No clear history for recent chest pain — but the patient "has not been well" for the previous week. Regarding the 2 ECGs in Figure-1 : ECG #1 is the initial tracing obtained at the scene by the EMS ( E mergency M edical S ystems ) team — in association with an alert but markedly hypotensive patient.

Blog 199
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Should You Take A Statin To Lower Your Cholesterol?

Dr. Paddy Barrett

Let’s start with the fact that this is not a yes or no answer. To answer this question, you need to understand three key factors: What is your baseline risk? Over what time horizon are you looking to reduce risk? What is your attitude toward reducing that risk? Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol.

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Weight-loss drug found to shrink heart muscle in mice and human cells

Medical Xpress - Cardiology

Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study in JACC: Basic to Translational Science. The authors say the research should serve as a "cautionary tale" about possible long-term health effects of these drugs.

Research 143
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COVID-19 infection appeared to increase risk of heart attack & stroke up to 3 years later

American Heart News - Heart News

Research Highlights: An analysis of UK Biobank health data that included adults who had mild to severe COVID-19 before vaccines were available found an increased risk of heart attack, stroke and death among those adults during the nearly three-year.

COVID-19 145
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New guideline: Preventing a first stroke may be possible with screening, lifestyle changes

American Heart News - Stroke News

Guideline Highlights: Each year in the U.S., over half a million people have a first stroke; however, up to 80% of strokes may be preventable. The new primary prevention of stroke guideline from the American Stroke Association urges health care.

Strokes 144
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Cognitive Performance Falls as Metal Exposure Rises

Med Page Today

(MedPage Today) -- Traces of nine essential metals and non-essential metals in urine were linked with lower cognitive performance and the risk of future dementia, a large prospective study showed. The study assessed concentrations of the essential.

Dementia 138
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Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

Cardiovascular Diabetology

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition that is characterized by unresolved fatigue, post-exertion symptom exacerbation (PESE), cognitive dysfunction, or.

Research 145

More Trending

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Live Updates from the FDA Psychopharmacologic Advisory Committee Meeting on MDMA for PTSD

HCPLive

Follow HCPLive's coverage of the full-day FDA committee meeting regarding Lykos Therapeutics' application for MDMA-assisted therapy as a novel treatment for patients with PTSD.

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Contemporary approach to cardiogenic shock care: a state-of-the-art review

Frontiers in Cardiovascular Medicine

Cardiogenic shock (CS) is a time-sensitive and hemodynamically complex syndrome with a broad spectrum of etiologies and clinical presentations. Despite contemporary therapies, CS continues to maintain high morbidity and mortality ranging from 35 to 50%. More recently, burgeoning observational research in this field aimed at enhancing the early recognition and characterization of the shock state through standardized team-based protocols, comprehensive hemodynamic profiling, and tailored and selec

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New evidence on the relationship between moderate wine consumption and cardiovascular health

Science Daily - Stroke

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.

Diet 110
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ECG Blog #462 — Why so Slow. ?

Ken Grauer, MD

I was sent the ECG in Figure-1 told only that the patient was an older adult who reported dizziness with activity. QUESTIONS: What is the rhythm? ( HINT: There are at least 4 important findings that should be noted ). Is there AV block? Figure-1: The initial ECG in today's case. ( To improve visualization I've digitized the original ECG using PMcardio ).

Blog 171
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One Of The Biggest Impact Things You Can Do To Live Longer.

Dr. Paddy Barrett

“But what can I do to make a difference?” This is one of the most common questions I get as a cardiologist when talking about preventing heart disease and living longer. As a doctor, there are many things I can do, and only a doctor can do: Prescribe medications Order certain diagnostic tests. Perform or arrange medical procedures. And so on.

Exercise 119
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History of COVID-19 found to double long-term risk of heart attack, stroke and death

Medical Xpress - Cardiology

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

COVID-19 145
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Heart failure, atrial fibrillation & coronary heart disease linked to cognitive impairment

American Heart News - Heart News

Statement Highlights: Previous studies have found that 14-81% of patients with heart failure experience some degree of cognitive impairment affecting language, memory or executive function. Evidence also indicates that people with atrial fibrillation.

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Mechanisms and treatment of pulmonary arterial hypertension

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 07 August 2024; doi:10.1038/s41569-024-01064-4 In this Review, Ghofrani and colleagues discuss the mechanisms underlying the development of pulmonary arterial hypertension, provide an overview of approved therapies and describe the predominantly non-vasodilatory drugs that are currently being tested in clinical trials.

Pulmonary 140
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Presidential Candidates Should Undergo Standardized Cognitive and Physical Testing

Med Page Today

(MedPage Today) -- Health professionals often perform the "eyeball test" when they first meet a patient. Through the power of observation, pixels of information are gathered quickly and often unconsciously to determine whether a patient is unwell.

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Nonpharmacological interventions on glycated haemoglobin in youth with type 1 diabetes: a Bayesian network meta-analysis

Cardiovascular Diabetology

The available evidence on the impact of specific non-pharmacological interventions on glycaemic control is currently limited. Consequently, there is a need to determine which interventions could provide the mo.

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8-hour time-restricted eating linked to a 91% higher risk of cardiovascular death

Science Daily - Heart Disease

A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease.

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FDA Approves Aprocitentan (Tryvio) for Treatment-Resistant Hypertension

HCPLive

Idorsia Ltd. announced the FDA's approval of aprocitentan (Tryvio) for treatment-resistant hypertension on March 20, 2024.

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New heart disease risk tool finds 40% fewer people need statins: Study

Becker's Hospital Review - Cardiology

New study suggests that 40% fewer people may need statins for heart disease prevention, according to a risk assessment published in JAMA Internal Medicine.

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The 40 Best Cardiology Newsletters, Websites, and Influencers to Follow in 2024

CardiacWire

We’re dedicating today’s top story to the people and publications that we rely on to find the most interesting cardiology stories from across the web. Assuming that you already subscribe to Cardiac Wire , these are the 40 other newsletters, websites, and social media stars to follow if you want to keep up with the latest and greatest in cardiology. I’ll always check the mainstream cardiology news websites ( TCTMD , Medscape , et al.) and the major cardiovascular journals ( JACC , AHA , JAMA Card

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ECG Blog #422 — Was Clubbing an ECG Hint?

Ken Grauer, MD

I was sent the ECG in Figure-1 — with the following history: The patient is a young man in his early 20s — who presents to the ED ( E mergency D epartment ) because of SOB ( S hortness O f B reath ) that had been ongoing for several hours. No chest pain. He reports a number of similar previous episodes over the past few years ( although apparently has not been formerly evaluated for this ).

Blog 187
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White adipocytes in subcutaneous fat depots require KLF15 for maintenance in preclinical models

Journal of Clinical Investigation - Cardiology

Healthy adipose tissue is essential for normal physiology. There are 2 broad types of adipose tissue depots: brown adipose tissue (BAT), which contains adipocytes poised to burn energy through thermogenesis, and white adipose tissue (WAT), which contains adipocytes that store lipids. However, within those types of adipose, adipocytes possess depot and cell-specific properties that have important implications.

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Caffeine intake linked to better vascular health in study

Medical Xpress - Cardiology

Consuming more caffeine may improve heart health, according to a study published in the Rheumatology journal.

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Primary care professionals key to helping people achieve & maintain heart health

American Heart News - Heart News

Statement Highlights: A new scientific statement outlines the role of primary care professionals in helping their patients achieve Life's Essential 8, the key measures for improving and maintaining cardiovascular health defined by the American Heart.

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The molecular landscape of vascular cells in the human brain

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 20 September 2024; doi:10.1038/s41569-024-01079-x A study using advanced single-cell technologies has broadened our understanding of the diversity and complexity of brain endothelial cells by uncovering new endothelial subtypes and transcriptional patterns. These findings offer insights into potential therapeutic targets and emphasize the need for further research on vascular lineages and neurovascular interactions.

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Shingles Tied to Long-Term Cognitive Changes

Med Page Today

(MedPage Today) -- Herpes zoster (shingles) was tied to an elevated risk of subjective cognitive decline, an analysis of 150,000 U.S. healthcare professionals showed. "In three large independent cohorts, herpes zoster was associated with an approximately.

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Ismail El-Hamamsy, MD, PhD, Named President of the Heart Valve Society

DAIC

Ismail El-Hamamsy, MD, performs a Ross Procedure at The Mount Sinai Hospital in New York City with Paul Stelzer, MD, and Elbert Williams, MD. Photo courtesy of Mount Sinai Health System milla1cf Thu, 02/22/2024 - 13:47 February 22, 2024 — Ismail El-Hamamsy , MD, PhD, Director of Aortic Surgery for the Mount Sinai Health System and the Mount Sinai Randall B.

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Ep 193 The Crashing Asthmatic – Recognition and Management of Life Threatening Asthma

ECG Cases

In this part 2 of our 2-part podcast on asthma with Dr. Sameer Mal and Dr. Leeor Sommer, we dig into the recognition and management of life-threatening asthma. We answer such questions as: what are the key elements in recognition of threatening asthma? What are the most time-sensitive interventions required to break the vicious cycle of asthma? What are the best options for dosing and administering magnesium sulphate, epinephrine, fentanyl and ketamine in the management of the crashing asthmatic

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Generic Liraglutide (Victoza) Becomes First Generic GLP-1 Receptor Agonist

HCPLive

Teva Pharmaceuticals’ launch of an authorized generic of liraglutide injection 1.8 mg (Victoza) for type 2 diabetes makes it the first-ever generic GLP-1.

Diabetes 142
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Can the heart heal itself? New study says it can

Science Daily - Heart Disease

Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

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Another deadly triage ECG missed, and the waiting patient leaves before being seen. What is this nearly pathognomonic ECG?

Dr. Smith's ECG Blog

Written by Bobby Nicholson, MD 67 year old male with history of hypertension and hyperlipidemia presented to the Emergency Department via ambulance with midsternal nonradiating chest pain and dyspnea on exertion. Pain improved to 1/10 after EMS administers 324 mg aspirin and the following EKG is obtained at triage. What do you think? If this EKG were handed to you to screen from triage without any clinical information, what would you think?

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ECG Blog #451 — Premature Closure.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — told only that the patient was a middle-aged man with septicemia. QUESTIONS: Is this rhythm too fast to be sinus tachycardia? Are flutter waves hidden within the QRS and T waves? Are we seeing the retrograde P waves of AVNRT? Is this ATach ( A trial T achycardia )? Figure-1: The initial ECG in today's case. MY Thoughts on Today’s CASE: In my opinion — none of the above answers are optimal to describe the rhythm in Figure-1.

Blog 170
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Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture

Journal of Clinical Investigation - Cardiology

Tissue regeneration is orchestrated by macrophages that clear damaged cells and promote regenerative inflammation. How macrophages spatially adapt and diversify their functions to support the architectural requirements of actively regenerating tissue remains unknown. In this study, we reconstructed the dynamic trajectories of myeloid cells isolated from acutely injured and early stage dystrophic muscles.

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Standing more may not reduce cardiovascular disease risk, could increase circulatory issues

Medical Xpress - Cardiology

Standing has gained popularity among people looking to offset the harms of a sedentary lifestyle often caused by spending long days sitting in front of the computer, television or driving wheel. Standing desks have become a popular option among office workers, and in other industries like retail, workers may opt to stand instead of sit.

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AI-powered tool may offer quick, no-contact blood pressure and diabetes screening

American Heart News - Heart News

Research Highlights: A preliminary study combining a patent-applied, AI-powered algorithm with a high-speed, 5-to 30-second video of skin on the face and the palm of the hand detected if someone had high blood pressure as well as using a blood.

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Cardiovascular autonomic dysfunction in post-COVID-19 syndrome: a major health-care burden

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 02 January 2024; doi:10.1038/s41569-023-00962-3 Cardiovascular autonomic dysfunction (CVAD) is a malfunction of the autonomic control of circulatory homeostasis and is an important component of post-COVID-19 syndrome. In this Review, Fedorowski and colleagues define the major forms of CVAD (including postural orthostatic tachycardia syndrome), and discuss the aetiology, diagnosis and management of post-COVID-19 syndrome-associated CVAD.

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