Sat.Sep 28, 2024 - Fri.Oct 04, 2024

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Falling May Be a Harbinger of Dementia in Older Adults

Med Page Today

(MedPage Today) -- A new diagnosis of Alzheimer's disease or related dementia was more common after falls than after other traumatic injuries, an analysis of Medicare claims data showed. The study assessed nearly 2.5 million older adults who had.

Dementia 130
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Frequent fizzy or fruit drinks and high coffee consumption linked to higher stroke risk

Science Daily - Stroke

Frequent drinking of fizzy drinks or fruit juice is associated with an increased risk of stroke, according to new findings. The research also found that drinking more than four cups of coffee per day also increases the risk of stroke.

Strokes 118
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ECG Blog #449 — Isorhythmic AV Dissociation?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from a 45-year old man with diabetes, who was being treated for septic shock. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? What is the rhythm? Why does QRS morphology in the long lead II rhythm strip change every-other-beat? Figure-1: The initial ECG in today's case. MY Thoughts on the ECG in Figure-1: This is a challenging ECG to interpret because of: i ) the changing QRS morphology; and , ii ) the difficulty in seeing all of the P waves.

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FDA Approves Exact Sciences’ Cologuard Plus Test for Colorectal Cancer Screening

HCPLive

The approval is based on findings from BLUE-C, where Cologuard Plus demonstrated sensitivities of 95% for colorectal cancer and 43% for advanced precancerous lesions at 94% specificity.

Cancer 115
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Study Finds More Heart Defects in Kids Conceived With ART

Med Page Today

(MedPage Today) -- Kids born via assisted reproductive technology (ART) had higher risk of congenital heart defects (CHDs), though the absolute risk difference was small, an observational Nordic study of 7.7 million children found. Major CHDs.

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Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing

Journal of Clinical Investigation - Cardiology

BACKGROUND Cystic kidney disease (CyKD) is a predominantly familial disease in which gene discovery has been led by family-based and candidate gene studies, an approach that is susceptible to ascertainment and other biases.METHODS Using whole-genome sequencing data from 1,209 cases and 26,096 ancestry-matched controls participating in the 100,000 Genomes Project, we adopted hypothesis-free approaches to generate quantitative estimates of disease risk for each genetic contributor to CyKD, across

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A 30-something with acute chest pain

Dr. Smith's ECG Blog

This was sent to me from Sam Ghali ( @EM_Resus ) with no other information. I assumed it was a patient with acute chest pain. "What do you think, Steve? Real or just fake?" What do YOU think? It has some inferior ST elevation with some reciprocal ST depression and inverted T in aVL. This usually indicates inferior OMI. My answer: "Fake: pretty certain, but not 100% certain.

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19th Annual Cardiometabolic Health Congress (CMHC): Your Insider’s Guide to Boston, MA 

Cardiometabolic Health Congress

Welcome to the 19th Annual Cardiometabolic Health Congress (Oct. 17-19) in Boston, where cutting-edge cardiorenal metabolic education meets the charm of one of America’s most historic cities! Our team of Boston event veterans has curated a list of must-see spots beyond the usual tourist attractions. Explore the hidden gems and iconic experiences that will make your time in Boston special.

Education 106
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3 ways to stay competitive in cardiology: 1 AdventHealth leader

Becker's Hospital Review - Cardiology

The "dichotomy" of great leaders, being more than transactional and creating a meaningful work environment are just three ways Gordon Wesley, vice president at AdventHealth Central Florida's Heart, Lung, & Vascular Institute in Orlando, is leading the industry with his cardiology program.

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New therapeutic target for cardiac arrhythmias emerges

Science Daily - Heart Disease

Researchers identified a lipid that is involved in regulating cardiac ion channels, providing insights into possible mechanisms of cardiac arrhythmias in heart failure and a potential pathway for future therapeutic development.

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5 FDA Decisions to Watch in Q4 2024

HCPLive

A review of 5 highly anticipated FDA decisions expected by year-end, including acoramidis for ATTR-CM, olezarsen for FCS, sotagliflozin for T1D and CKD, and more.

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Cardiac Myosin Inhibition in Heart Failure With Normal and Supranormal Ejection Fraction

JAMA Cardiology

The EMBARK-HFpEF multicenter, open-label trial examines the effects of cardiac myosin inhibition with mavacamten in patients with heart failure with preserved ejection fraction with a left ventricular ejection fraction of 60% or greater.

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Timeline of Irregular Heartbeats Emerges From Close Watch of Young Binge Drinkers

Med Page Today

(MedPage Today) -- Continuous rhythm monitoring showed the timeline in which heart rate and atrial tachycardias typically arise after binge drinking by young adults, researchers reported. In people with no known history of cardiac arrhythmias.

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1 in 4 Americans will develop heart failure: What healthcare leaders should know

Becker's Hospital Review - Cardiology

One in 4 Americans (24%) will develop heart failure in their lifetime, according to a new report published Sept. 24 in the Journal of Cardiac Failure.

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Gender, IgA Nephropathy Linked to Gross Hematuria After COVID-19 Vaccination

HCPLive

Gross hematuria after COVID-19 mRNA vaccination was more likely in females, patients with IgAN/IgAV, and after the second and third vaccine doses.

COVID-19 120
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ECG Cases 51 – ECGs falsely labeled “normal”

ECG Cases

In this ECG Cases blog we look at 5 cases of ECGs falsely labeled 'normal'. Can you spot the critical abnormality? Written by Jesse McLaren; Peer Reviewed and edited by Anton Helman. October 2024 Five patients presented with ECGs labeled ‘normal’. Can you use systematic ECG interpretation to identify the [.] The post ECG Cases 51 – ECGs falsely labeled “normal” appeared first on Emergency Medicine Cases.

Blog 100
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VT in a Sick Patient? Paired with 2 old cases (see it at the bottom)

Dr. Smith's ECG Blog

== MY Comment , by K EN G RAUER, MD ( 8/30 /2024 ): == I was sent the ECG shown in Figure-1 — knowing only that the patient was being seen in the ED ( E mergency D epartment ). How would you interpret this tracing? Figure-1: The initial ECG in today's case. MY Initial Thoughts: In my experience — all-too-many emergency providers fail to appreciate the potential contribution that a brief ( 1-to-2 line ) history may convey when interpreting arrhythmias.

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Study proposes new heart failure treatment targeting abnormal hormone activity

Science Daily - Heart Disease

Scientists discovered that blocking the activity of the hormone glucagon could treat a common and challenging type of heart failure that affects millions worldwide.

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Schizophrenia Patients Face High Mental Health Comorbidity, Limited Treatment

HCPLive

A study reveals that individuals with schizophrenia spectrum disorders experience high rates of comorbid mental health conditions and receive minimally adequate treatment.

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Austin Thomas Erb

Conquering CHD

9.14.22-11.26.22 When we first learned that Austin would be admitted to Rocky Mountain Hospital for Children PICU for open heart surgery at 3 weeks old, we were nervous and anxious for what was ahead. However, nothing would truly prepare us for what the next 53 days would bring. The feeling of leaving your baby in the hands of another is daunting and emotional but we never doubted for one moment that the staff didn’t love him as if he was their own.

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What Skin Says About Health

Med Page Today

(MedPage Today) -- Internal medicine and rheumatology specialist Siobhan Deshauer, MD, reviews the underlying pathophysiology of common skin conditions. Following is a partial transcript of the video (note that errors are possible): Deshauer.

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New laser-based headset can measure blood flow, assess risk of stroke

Science Daily - Stroke

Researchers have developed a laser-based device that can measure blood flow noninvasively and differentiate stroke risk based on current physiological conditions.

Stroke 96
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Pregnant IgAN Patients with Adverse Outcomes Less Likely to Reach Proteinuria Remission

HCPLive

A study found pregnant patients with IgA nephropathy and adverse pregnancy outcomes were less likely to achieve proteinuria remission, though renal function remained unaffected.

Outcomes 105
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Reduced risk of serious cardiovascular disease after COVID vaccination

Science Daily - Heart Disease

People who have been fully vaccinated against COVID-19 have a significantly lower risk of developing more severe cardiovascular conditions linked to COVID-19 infection, according to a new Swedish study. At the same time, some cardiovascular effects are seen after individual doses of the vaccine.

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Metabolic Accelerator Shows Promise for Weight Loss Side of Obesity-HFpEF Equation

Med Page Today

(MedPage Today) -- The novel investigational weight loss agent HU6 had mixed results specifically targeting obesity-related heart failure with preserved ejection fraction (HFpEF), based on the small HuMain-HFpEF trial. After 19 weeks on daily.

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New Study Highlights Life-Saving Impact of Guideline-Directed Medical Therapy in Heart Failure Patients

DAIC

tim.hodson Wed, 10/02/2024 - 11:54 Heart failure is a rapidly growing public health issue that can be difficult to manage on a global scale. But there are tools that exist that can improve outcomes, such as guideline-directed medical therapy (GDMT). New UCLA-led research highlights the important role that these guidelines can play in reducing mortality rates for individuals suffering from heart failure with reduced ejection fraction (HFrEF), a type of heart failure affecting an estimated 29 mill

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Hidradenitis Suppurativa Does Not Increase Female Infertility Risk, Study Finds

HCPLive

Contrary to previous research, findings suggest no significant difference in infertility between patients with HS, other dermatological diseases, and healthy controls.

Research 105
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Deep brain stimulation instantly improves arm and hand function post-brain injury

Science Daily - Stroke

Deep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or stroke.

Stroke 96
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Happy People, Happy Hearts? Ultra-Processed Foods and Diabetes Risk

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

Diabetes 110
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Nominate a stroke hero today: 2025 Stroke Hero Awards open for submissions

American Heart News - Stroke News

DALLAS, Oct. 1, 2024 - Strokes can strike at any age, challenging survivors to overcome physical, emotional and cognitive changes. Nominations are open now for the 2025 Stroke Hero Awards from the American Stroke Association, a division of the.

Stroke 84
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Matched Analysis Finds No Link Between Dupilumab Use and Adverse Pregnancy Outcomes

HCPLive

An EADV 2024 study suggests dupilumab use during pregnancy is generally safe and may lower risks of preterm labor, gestational hypertension, and diabetes.

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Unlocking new regenerative pathways in iPS cell–derived epicardium for cardiac repair

Medical Xpress - Cardiology

Efforts to foster both intrinsic and extrinsic regenerative responses in heart failure have once again brought iPS cell technologies to the forefront, thanks to their flexibility in reconstructing tissues in vitro and enabling researchers to investigate the biological mechanisms driving cell-fate decisions.

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Mavacamten Shows Promise in Heart Failure With Normal to Supranormal EF

Med Page Today

(MedPage Today) -- There may be a future for cardiac myosin inhibitors in heart failure with preserved ejection fraction (HFpEF), according to the proof-of-concept EMBARK-HFpEF trial. An established cardiac myosin inhibitor for hypertrophic cardiomyopathy.

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50 yo with V fib has ROSC, then these 2 successive ECGs: what is the infarct artery?

Dr. Smith's ECG Blog

A 50 yo was resuscitated from ventricular fibrillation. He had a prehospital ECG recorded after ROSC: What do you think? This certainly looks like an anterior STEMI (proximal LAD occlusion), with STE and hyperacute T-waves (HATW) in V2-V6 and I and aVL. Although one may have all kinds of ischemic findings as a result of cardiac arrest (rather than cause of cardiac arrest), this degree of ST elevation and HATW is all but diagnostic of acute proximal LAD occlusion.

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Faster Weight Loss on Anti-Obesity Medication Correlated With Lower Risk of Gout

HCPLive

Compared with participants who gained weight or who weight remained stable, the risk of developing gout fell with increased weight loss over 1 year.

Obesity 111
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Study finds high endocarditis mortality rates for those who inject drugs, but treatment dramatically improves survival

Medical Xpress - Cardiology

People who inject drugs are dying at an alarming rate from endocarditis, a serious but treatable heart-valve infection. But their odds of survival improve dramatically, even five years after their first admission to hospital, if they're treated not just for heart infection but are also provided with addiction support while in hospital, a Canadian study shows.

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VR Headsets in Cath Lab; ICDs & Driving Rules; How Cardiologist Got to Space

Med Page Today

(MedPage Today) -- A look at the feasibility of coronary angiography and angioplasty procedures using the Meta Quest 3 virtual reality (VR) headset. (European Heart Journal) FDA approved flurpiridaz F-18 (Flyrcado), a radiotracer for positron.