Sat.Sep 28, 2024 - Fri.Oct 04, 2024

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Falling May Be a Harbinger of Dementia in Older Adults

Med Page Today

(MedPage Today) -- A new diagnosis of Alzheimer's disease or related dementia was more common after falls than after other traumatic injuries, an analysis of Medicare claims data showed. The study assessed nearly 2.5 million older adults who had.

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Subclinical Atherosclerosis Burden Shapes All-Cause Mortality Risk

HCPLive

Subclinical atherosclerosis burden and its progression are independently linked to the risk of death from any cause in asymptomatic individuals.

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A 30-something with acute chest pain

Dr. Smith's ECG Blog

This was sent to me from Sam Ghali ( @EM_Resus ) with no other information. I assumed it was a patient with acute chest pain. "What do you think, Steve? Real or just fake?" What do YOU think? It has some inferior ST elevation with some reciprocal ST depression and inverted T in aVL. This usually indicates inferior OMI. My answer: "Fake: pretty certain, but not 100% certain.

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Frequent fizzy or fruit drinks and high coffee consumption linked to higher stroke risk

Science Daily - Stroke

Frequent drinking of fizzy drinks or fruit juice is associated with an increased risk of stroke, according to new findings. The research also found that drinking more than four cups of coffee per day also increases the risk of stroke.

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Study Finds More Heart Defects in Kids Conceived With ART

Med Page Today

(MedPage Today) -- Kids born via assisted reproductive technology (ART) had higher risk of congenital heart defects (CHDs), though the absolute risk difference was small, an observational Nordic study of 7.7 million children found. Major CHDs.

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Gender, IgA Nephropathy Linked to Gross Hematuria After COVID-19 Vaccination

HCPLive

Gross hematuria after COVID-19 mRNA vaccination was more likely in females, patients with IgAN/IgAV, and after the second and third vaccine doses.

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When patients worry about being judged

Heart Sisters

There’s a lot of judgey judging of chronically ill patients going on out there.

More Trending

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Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing

Journal of Clinical Investigation - Cardiology

BACKGROUND Cystic kidney disease (CyKD) is a predominantly familial disease in which gene discovery has been led by family-based and candidate gene studies, an approach that is susceptible to ascertainment and other biases.METHODS Using whole-genome sequencing data from 1,209 cases and 26,096 ancestry-matched controls participating in the 100,000 Genomes Project, we adopted hypothesis-free approaches to generate quantitative estimates of disease risk for each genetic contributor to CyKD, across

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5 FDA Decisions to Watch in Q4 2024

HCPLive

A review of 5 highly anticipated FDA decisions expected by year-end, including acoramidis for ATTR-CM, olezarsen for FCS, sotagliflozin for T1D and CKD, and more.

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VT in a Sick Patient? Paired with 2 old cases (see it at the bottom)

Dr. Smith's ECG Blog

== MY Comment , by K EN G RAUER, MD ( 8/30 /2024 ): == I was sent the ECG shown in Figure-1 — knowing only that the patient was being seen in the ED ( E mergency D epartment ). How would you interpret this tracing? Figure-1: The initial ECG in today's case. MY Initial Thoughts: In my experience — all-too-many emergency providers fail to appreciate the potential contribution that a brief ( 1-to-2 line ) history may convey when interpreting arrhythmias.

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1 in 4 Americans will develop heart failure: What healthcare leaders should know

Becker's Hospital Review - Cardiology

One in 4 Americans (24%) will develop heart failure in their lifetime, according to a new report published Sept. 24 in the Journal of Cardiac Failure.

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Reduced risk of serious cardiovascular disease after COVID vaccination

Science Daily - Heart Disease

People who have been fully vaccinated against COVID-19 have a significantly lower risk of developing more severe cardiovascular conditions linked to COVID-19 infection, according to a new Swedish study. At the same time, some cardiovascular effects are seen after individual doses of the vaccine.

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FDA Approves Exact Sciences’ Cologuard Plus Test for Colorectal Cancer Screening

HCPLive

The approval is based on findings from BLUE-C, where Cologuard Plus demonstrated sensitivities of 95% for colorectal cancer and 43% for advanced precancerous lesions at 94% specificity.

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19th Annual Cardiometabolic Health Congress (CMHC): Your Insider’s Guide to Boston, MA 

Cardiometabolic Health Congress

Welcome to the 19th Annual Cardiometabolic Health Congress (Oct. 17-19) in Boston, where cutting-edge cardiorenal metabolic education meets the charm of one of America’s most historic cities! Our team of Boston event veterans has curated a list of must-see spots beyond the usual tourist attractions. Explore the hidden gems and iconic experiences that will make your time in Boston special.

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3 ways to stay competitive in cardiology: 1 AdventHealth leader

Becker's Hospital Review - Cardiology

The "dichotomy" of great leaders, being more than transactional and creating a meaningful work environment are just three ways Gordon Wesley, vice president at AdventHealth Central Florida's Heart, Lung, & Vascular Institute in Orlando, is leading the industry with his cardiology program.

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50 yo with V fib has ROSC, then these 2 successive ECGs: what is the infarct artery?

Dr. Smith's ECG Blog

A 50 yo was resuscitated from ventricular fibrillation. He had a prehospital ECG recorded after ROSC: What do you think? This certainly looks like an anterior STEMI (proximal LAD occlusion), with STE and hyperacute T-waves (HATW) in V2-V6 and I and aVL. Although one may have all kinds of ischemic findings as a result of cardiac arrest (rather than cause of cardiac arrest), this degree of ST elevation and HATW is all but diagnostic of acute proximal LAD occlusion.

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Faster Weight Loss on Anti-Obesity Medication Correlated With Lower Risk of Gout

HCPLive

Compared with participants who gained weight or who weight remained stable, the risk of developing gout fell with increased weight loss over 1 year.

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ECG Blog #449 — Isorhythmic AV Dissociation?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from a 45-year old man with diabetes, who was being treated for septic shock. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? What is the rhythm? Why does QRS morphology in the long lead II rhythm strip change every-other-beat? Figure-1: The initial ECG in today's case. MY Thoughts on the ECG in Figure-1: This is a challenging ECG to interpret because of: i ) the changing QRS morphology; and , ii ) the difficulty in seeing all of the P waves.

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New therapeutic target for cardiac arrhythmias emerges

Science Daily - Heart Disease

Researchers identified a lipid that is involved in regulating cardiac ion channels, providing insights into possible mechanisms of cardiac arrhythmias in heart failure and a potential pathway for future therapeutic development.

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Happy People, Happy Hearts? Ultra-Processed Foods and Diabetes Risk

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Schizophrenia Patients Face High Mental Health Comorbidity, Limited Treatment

HCPLive

A study reveals that individuals with schizophrenia spectrum disorders experience high rates of comorbid mental health conditions and receive minimally adequate treatment.

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Use of artificial intelligence-powered ECG to differentiate between cardiac and pulmonary pathologies in patients with acute dyspnoea in the emergency department

Open Heart

Background Acute dyspnoea is common in acute care settings. However, identifying the origin of dyspnoea in the emergency department (ED) is often challenging. We aimed to investigate whether our artificial intelligence (AI)-powered ECG analysis reliably distinguishes between the causes of dyspnoea and evaluate its potential as a clinical triage tool for comparing conventional heart failure diagnostic processes using natriuretic peptides.

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Study proposes new heart failure treatment targeting abnormal hormone activity

Science Daily - Heart Disease

Scientists discovered that blocking the activity of the hormone glucagon could treat a common and challenging type of heart failure that affects millions worldwide.

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Timeline of Irregular Heartbeats Emerges From Close Watch of Young Binge Drinkers

Med Page Today

(MedPage Today) -- Continuous rhythm monitoring showed the timeline in which heart rate and atrial tachycardias typically arise after binge drinking by young adults, researchers reported. In people with no known history of cardiac arrhythmias.

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Matched Analysis Finds No Link Between Dupilumab Use and Adverse Pregnancy Outcomes

HCPLive

An EADV 2024 study suggests dupilumab use during pregnancy is generally safe and may lower risks of preterm labor, gestational hypertension, and diabetes.

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Austin Thomas Erb

Conquering CHD

9.14.22-11.26.22 When we first learned that Austin would be admitted to Rocky Mountain Hospital for Children PICU for open heart surgery at 3 weeks old, we were nervous and anxious for what was ahead. However, nothing would truly prepare us for what the next 53 days would bring. The feeling of leaving your baby in the hands of another is daunting and emotional but we never doubted for one moment that the staff didn’t love him as if he was their own.

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Nominate a stroke hero today: 2025 Stroke Hero Awards open for submissions

American Heart News - Stroke News

DALLAS, Oct. 1, 2024 - Strokes can strike at any age, challenging survivors to overcome physical, emotional and cognitive changes. Nominations are open now for the 2025 Stroke Hero Awards from the American Stroke Association, a division of the.

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What Skin Says About Health

Med Page Today

(MedPage Today) -- Internal medicine and rheumatology specialist Siobhan Deshauer, MD, reviews the underlying pathophysiology of common skin conditions. Following is a partial transcript of the video (note that errors are possible): Deshauer.

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Bimekizumab Improves Pain, Fatigue, and More in Active Psoriatic Arthritis Over Placebo

HCPLive

A greater portion of patients treated with bimekizumab achieved minimal clinically important differences than with placebo.

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New Study Highlights Life-Saving Impact of Guideline-Directed Medical Therapy in Heart Failure Patients

DAIC

tim.hodson Wed, 10/02/2024 - 11:54 Heart failure is a rapidly growing public health issue that can be difficult to manage on a global scale. But there are tools that exist that can improve outcomes, such as guideline-directed medical therapy (GDMT). New UCLA-led research highlights the important role that these guidelines can play in reducing mortality rates for individuals suffering from heart failure with reduced ejection fraction (HFrEF), a type of heart failure affecting an estimated 29 mill

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Cardiac Myosin Inhibition in Heart Failure With Normal and Supranormal Ejection Fraction

JAMA Cardiology

The EMBARK-HFpEF multicenter, open-label trial examines the effects of cardiac myosin inhibition with mavacamten in patients with heart failure with preserved ejection fraction with a left ventricular ejection fraction of 60% or greater.

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Metabolic Accelerator Shows Promise for Weight Loss Side of Obesity-HFpEF Equation

Med Page Today

(MedPage Today) -- The novel investigational weight loss agent HU6 had mixed results specifically targeting obesity-related heart failure with preserved ejection fraction (HFpEF), based on the small HuMain-HFpEF trial. After 19 weeks on daily.

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Secukinumab Surpasses Ustekinumab in Clearing Skin for Generalized Pustular Psoriasis

HCPLive

A study shows secukinumab clears skin lesions faster than ustekinumab in generalized pustular psoriasis, with improved responses observed by week 2.

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Deep brain stimulation instantly improves arm and hand function post-brain injury

Science Daily - Stroke

Deep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or stroke.

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At What Age Should You Think About Assessing Your Risk For Heart Disease?

Dr. Paddy Barrett

There is a phrase in aviation: “The most useless part of the runway is the runway that is behind you” A runway might be a mile long, but if you start your takeoff roll at the halfway mark, it doesn’t really matter that the runway is a mile long. You now only have half a mile left to work with. The same principle applies to assessing and managing your risk of heart disease.

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Mavacamten Shows Promise in Heart Failure With Normal to Supranormal EF

Med Page Today

(MedPage Today) -- There may be a future for cardiac myosin inhibitors in heart failure with preserved ejection fraction (HFpEF), according to the proof-of-concept EMBARK-HFpEF trial. An established cardiac myosin inhibitor for hypertrophic cardiomyopathy.

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Adherence to Phototherapy for Psoriasis Influenced by Patient Variables

HCPLive

A small percentage of participants with psoriasis reported adequate adherence, with nearly half showing low adherence to phototherapy treatment.

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