Physiologically Speaking

DECEMBER 17, 2024

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. This has raised concerns that long-term, high-volume exercise might be detrimental to heart health.

Risk Factors 99

Risk Factors Genetic predisposition Plaque Exercise 99

Medical Xpress - Cardiology

DECEMBER 19, 2024

We sing about how Christmas brings "tidings of comfort and joy," but the holiday also brings something not so "merry and bright.

Heart Attack 103

Heart Attack Heart attacks 103

Med Page Today

DECEMBER 18, 2024

(MedPage Today) -- Moderate wine consumption maintained its association with cardiovascular benefit when self-reports were taken out of the equation, the large PREDIMED trial showed. Using urinary tartaric acid as an objective biomarker measuring.

Biomarkers 98

Biomarkers 98

Science Daily - Stroke

DECEMBER 18, 2024

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.

Diet 83

Diet Biomarkers 83

Journal of Clinical Investigation - Cardiology

DECEMBER 16, 2024

Aging negatively affects the capacity of muscle stem cells (MuSCs) to regenerate muscle. In this issue of the JCI, Ancel, Michaud, and colleagues used a high-content imaging screen to identify nicotinamide and pyridoxine as promoters of MuSC function. The combination of the two compounds promoted MuSC function in vivo in aged mice and in primary cells isolated from older individuals.

Circulation 95

Circulation 95

Medical Xpress - Cardiology

DECEMBER 20, 2024

Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.

Research 96

Research 96

Med Page Today

DECEMBER 17, 2024

(MedPage Today) -- A 53-year-old woman is free from dialysis after receiving a gene-edited pig kidney transplant at NYU Langone Health, doctors announced on Tuesday. The 7-hour surgery was performed on November 25, marking the third time that.

Transplant 98

Transplant 98

Dr. Paddy Barrett

DECEMBER 20, 2024

As a cardiologist, I am frequently asked about supplements and heart health. In general, I am not a fan. Personally, I take two supplements. Whey protein for hitting my daily protein targets. Creatine for improving exercise performance and muscle mass. Neither of these supplements is for improving ‘heart health’ During the winter months, I will occasionally take vitamin D if my levels are low, but generally, if I get enough time outside, even during the winter months, I do not need t

Blood Pressure 63

Blood Pressure Heart Attack Heart attacks Coronary Artery Disease 63

Medical Xpress - Cardiology

DECEMBER 17, 2024

Drinking a small or moderate amount of wine may lower the risk of serious cardiovascular disease in people at a higher risk who are following a Mediterranean diet, according to research published in the European Heart Journal.

Cardiovascular Disease 94

Cardiovascular Disease Diet Research 94

Med Page Today

DECEMBER 19, 2024

(MedPage Today) -- The shortage of the diabetes and obesity injectable tirzepatide (Mounjaro, Zepbound) has been resolved, the FDA announced Thursday. As a result, compounders will have a grace period of 60 to 90 days to wrap up production and.

Obesity 87

Obesity Diabetes 87

HCPLive

DECEMBER 18, 2024

Findings suggest an association between food allergies and atopic dermatitis control and persistence.

Pediatrics 75

Pediatrics 75

Science Daily - Heart Disease

DECEMBER 16, 2024

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.

Atrial Fibrillation 76

Atrial Fibrillation Myocardial Infarction Kidney Disease Dementia 76

Medical Xpress - Cardiology

DECEMBER 19, 2024

A new study by the German Center for Cardiovascular Research (DZHK) shows that people on low incomes who are also exposed to high levels of traffic noise have a significantly increased risk of serious cardiovascular disease. The findings highlight the need to tackle social inequalities and environmental pollution together to improve the health of disadvantaged populations.

Cardiovascular Disease 87

Cardiovascular Disease Research 87

Cardiovascular Diabetology

DECEMBER 20, 2024

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

Genetic predisposition 64

Genetic predisposition Cardiovascular Disease Diabetes Hypertension 64

HCPLive

DECEMBER 16, 2024

Needle-free treatments, such as Neffy and FluMist, offer promising alternatives for children and adults with needle phobia, ensuring access to critical care.

Critical Care 78

Critical Care 78

Science Daily - Heart Disease

DECEMBER 20, 2024

Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

Artificial Heart 66

Artificial Heart Heart Failure 66

Medical Xpress - Cardiology

DECEMBER 19, 2024

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterolhigh-density lipoproteins (HDL)may be associated with an increased prevalence of cardiovascular disease.

Cholesterol 87

Cholesterol Cardiovascular Disease Research 87

The New England Journal of Medicine

DECEMBER 18, 2024

A 63-year-old man with a history of CABG presented with a 2-month history of angina during exertion of the left arm. Angiography revealed retrograde flow in the left internal thoracic artery graft (shown in a video).

Angina 68

Angina 68

Journal of Clinical Investigation - Cardiology

DECEMBER 16, 2024

Despite the impressive clinical benefits and widespread adoption of sodium glucose cotransporter 2 inhibitors (SGLT2i) to treat all classes of heart failure, their cardiovascular mechanisms of action are poorly understood. Proposed mechanisms range broadly and include enhanced ketogenesis, where the mild ketosis associated with SGLT2i use is presumed to be beneficial.

Heart Failure 72

Heart Failure 72

Science Daily - Heart Disease

DECEMBER 19, 2024

Researchers have discovered that certain components of so-called 'good' cholesterol -- high-density lipoproteins (HDL) -- may be associated with an increased prevalence of cardiovascular disease.

Cholesterol 64

Cholesterol Cardiovascular Disease Research 64

Medical Xpress - Cardiology

DECEMBER 19, 2024

Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association.

Atrial Fibrillation 82

Atrial Fibrillation Research AFIB 82

Dr. Smith's ECG Blog

DECEMBER 16, 2024

Which patient needs a CT Scan? Case 1: 20-something woman with chest pain Case 2: 50-something man with chest pain Case 1 A 20-something yo woman presented in the middle of the night with severe crushing chest pain. It had begun 4 hours before arrival and was initially dull, but became severe and "unbearable" 2 hours prior to arrival. She was a walk-in at triage.

Chest Pain 65

Chest Pain Aortic STEMI Ultrasound 65

Cardiovascular Diabetology

DECEMBER 20, 2024

Data on the relationship between potassium intake and major cardiovascular events (MACE) in patients with diabetes are scarce. We aim to study the association between estimated potassium intake and risk of MAC.

Diabetes 59

Diabetes Research 59

Science Daily - Heart Disease

DECEMBER 18, 2024

Researchers studied oxygen treatment as a potential therapy to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes and found no significant improvement in function in patients with type 2 diabetes.

Diabetes 65

Diabetes Blood Pressure Research 65

Medical Xpress - Cardiology

DECEMBER 15, 2024

It's the time of year for workplace Christmas parties, and gatherings with family and friends. Maybe you'll drink a lot in one go.

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80

Dr. Smith's ECG Blog

DECEMBER 20, 2024

Written by Willy Frick with edits by Ken Grauer An older man with a history of non-ischemic HFrEF s/p CRT and mild coronary artery disease presented with chest pain. He said he had had three episodes of chest pain that day while urinating. The following ECG was obtained in the emergency department during active chest pain. ECG 1 What do you think? There is a lot going on in this ECG.

Chest Pain 57

Chest Pain Tachycardia Pacemaker Defibrillator 57

HCPLive

DECEMBER 20, 2024

The FDA's decision not to approve sotagliflozin as an adjunct in T1D and CKD comes less than 2 months after a negative advisory committee meeting for the application.

Diabetes 59

Diabetes 59

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

Despite improvements in clinical outcomes of acute myocardial infarction (AMI), mortality rates remain high, indicating the need for further understanding of the pathogenesis and developing more effective cardiac protection strategies. Extracellular vesicles (EVs) carry proteins and noncoding RNAs (ncRNAs) derived from different cardiac cell populations, mainly including cardiomyocytes, endothelial cells, endothelial progenitor cells, cardiac progenitor cells, cardiosphere-derived cells, immune

Myocardial Infarction 52

Myocardial Infarction Biomarkers Physiology Innovation 52

Medical Xpress - Cardiology

DECEMBER 20, 2024

UC Davis Director of Pediatric Electrophysiology Dan Cortez has set another world record: He is the first to implant a dual chamber leadless pacemaker in a child. His case report was published this week in the journal Pacing and Clinical Electrophysiology.

Pacemaker 69

Pacemaker Electrophysiology Pediatrics 69

Cardiovascular Diabetology

DECEMBER 18, 2024

Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have emerged as important agents for the treatment of type 2 diabetes mellitus (T2DM). SGLT2 inhibitors have been associated with improved cardiovascular out.

Diabetes 59

Diabetes 59

HCPLive

DECEMBER 20, 2024

Tirzepatide's approval marks the first and only prescription medicine available for adults with moderate-to-severe obstructive sleep apnea and obesity.

Obesity 59

Obesity 59

AMS Cardiology

DECEMBER 16, 2024

The magic of the holidays often comes with hidden challenges for our hearts. Rich foods, packed calendars, and holiday pressures can derail even our best health intentions. Yet maintaining heart health doesn’t mean sacrificing the festivities. Simple, mindful choices during the holiday season can protect your cardiovascular health and lay the foundation for a lively year ahead.

Blood Pressure 52

Blood Pressure Risk Factors Diet Cholesterol 52

Medical Xpress - Cardiology

DECEMBER 16, 2024

Continuously monitoring a person's pulse can provide meaningful medical information, such as heart rate and, indirectly, blood pressure. However, pulse waves can vary dramatically from person to person and even within the same person at different times of day and during different activities. These variations make it difficult for current wearable pulse sensors to accurately record useful data, which is especially problematic for those with cardiovascular disease or high-risk factors for those di

Blood Pressure 77

Blood Pressure Risk Factors Cardiovascular Disease 77

Science Daily - Heart Disease

DECEMBER 16, 2024

The lateral habenula is a brain region associated with behavioral changes and autonomic responses during psychological stress. Researchers at the University of Tsukuba have identified the involvement of the dopaminergic system in the cardiovascular responses triggered by neuronal excitation in the lateral habenula. They further determined that the ventral tegmental area of the midbrain, which is the origin of dopamine neurons, plays a mediating role in this response.

Research 61

Research 61

HCPLive

DECEMBER 20, 2024

These data resulted from an investigation of the effect of varying image qualities on the diagnostic abilities of a convolutional neural network (CNN) model and clinicians.

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Cardiovascular Diabetology

DECEMBER 17, 2024

Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus and causes vision impairment and blindness. The presence of major risk factors for DR, such as high levels of HbA1c, does no.

Diabetes 59

Diabetes Biomarkers Risk Factors Research 59

Medical Xpress - Cardiology

DECEMBER 19, 2024

A collaborative study from physician researchers at the University of Cincinnati College of Medicine is shining new light on current guidelines for delivery timing in pregnant mothers with chronic hypertension.

Hypertension 71

Hypertension Research 71