Sat.Dec 14, 2024 - Fri.Dec 20, 2024

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New evidence on the relationship between moderate wine consumption and cardiovascular health

Science Daily - Stroke

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.

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Can the heart heal itself? New study says it can

Science Daily - Heart Disease

Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

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Research suggests coffee may protect against cognitive decline in people with atrial fibrillation

Medical Xpress - Cardiology

Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association.

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Lifestyle Risk Factors Predict Coronary Calcification among Male Endurance Athletes

Physiologically Speaking

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. This has raised concerns that long-term, high-volume exercise might be detrimental to heart health.

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Sedentary Behavior Linked to Increased Gout Risk Even Without Hyperuricemia

HCPLive

A study found the association between sedentary behavior and gout remained strong even when adjusting for physical activity.

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The muscle stem cell case of Benjamin Button: rejuvenating muscle regenerative capacity through nutraceuticals

Journal of Clinical Investigation - Cardiology

Aging negatively affects the capacity of muscle stem cells (MuSCs) to regenerate muscle. In this issue of the JCI, Ancel, Michaud, and colleagues used a high-content imaging screen to identify nicotinamide and pyridoxine as promoters of MuSC function. The combination of the two compounds promoted MuSC function in vivo in aged mice and in primary cells isolated from older individuals.

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Using an AI tool, researchers find poor vascular health accelerates brain aging

Medical Xpress - Cardiology

Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.

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Diabetes Dialogue: Celebrating 2024 - The Year of the Continuous Glucose Monitor

HCPLive

In this episode, hosts reflect on the advancement in CGM that reshaped care for diabetes and overall health during 2024.

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Best Supplements For Heart Health.

Dr. Paddy Barrett

As a cardiologist, I am frequently asked about supplements and heart health. In general, I am not a fan. Personally, I take two supplements. Whey protein for hitting my daily protein targets. Creatine for improving exercise performance and muscle mass. Neither of these supplements is for improving ‘heart health’ During the winter months, I will occasionally take vitamin D if my levels are low, but generally, if I get enough time outside, even during the winter months, I do not need t

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There are more heart attacks on Christmas than any other day of the year

Medical Xpress - Cardiology

We sing about how Christmas brings "tidings of comfort and joy," but the holiday also brings something not so "merry and bright.

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Engineering extracellular vesicles for targeted therapeutics in cardiovascular disease

Frontiers in Cardiovascular Medicine

Extracellular vesicles (EVs) are nanosized particles secreted by cells that play crucial roles in intercellular communication, especially in the context of cardiovascular diseases (CVDs). These vesicles carry complex cargo, including proteins, lipids, and nucleic acids, that reflects the physiological or pathological state of their cells of origin. Multiomics analysis of cell-derived EVs has provided valuable insights into the molecular mechanisms underlying CVDs by identifying specific proteins

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Colchicine Prophylaxis for Gout Flares Linked to Lower Cardiovascular Events

HCPLive

These findings, from an observational study, should be confirmed in a randomized, controlled trial.

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SGLT2 inhibition and adipose tissue metabolism: current outlook and perspectives

Cardiovascular Diabetology

Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have emerged as important agents for the treatment of type 2 diabetes mellitus (T2DM). SGLT2 inhibitors have been associated with improved cardiovascular out.

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Cardiovascular Protection Tracks With Wine Intake, Now Provable With Urinary Marker

Med Page Today

(MedPage Today) -- Moderate wine consumption maintained its association with cardiovascular benefit when self-reports were taken out of the equation, the large PREDIMED trial showed. Using urinary tartaric acid as an objective biomarker measuring.

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Surprising discovery pinpoints when good cholesterol becomes harmful

Medical Xpress - Cardiology

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterolhigh-density lipoproteins (HDL)may be associated with an increased prevalence of cardiovascular disease.

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Brexpiprazole with Sertraline Significantly Reduces PTSD Symptoms in 10 Days

HCPLive

A phase 3 trial shows promising data for brexpiprazole with sertraline for PTSD symptoms ahead of the supplemental new drug applications PDUFA date in February 2024.

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Anti-inflammatory effects of glucagon-like peptide-1 (GLP-1) in coronary artery disease: a comprehensive review

Frontiers in Cardiovascular Medicine

Coronary artery disease (CAD)cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteriesis responsible for disabilities of millions of people worldwide and remains the most common single cause of death. Inflammation is the primary pathological mechanism underlying CAD, since is involved in atherosclerotic plaque formation.

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Woman Dialysis-Free After Receiving Gene-Edited Pig Kidney

Med Page Today

(MedPage Today) -- A 53-year-old woman is free from dialysis after receiving a gene-edited pig kidney transplant at NYU Langone Health, doctors announced on Tuesday. The 7-hour surgery was performed on November 25, marking the third time that.

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Clopidogrel edges out aspirin in heart procedure recovery

Medical Xpress - Cardiology

Researchers at 37 sites in South Korea have found patients taking clopidogrel after percutaneous coronary intervention (PCI) experienced lower rates of both thrombotic and bleeding events than those taking aspirin. Clopidogrel's benefits remained consistent regardless of high bleeding risk (HBR) or complex PCI.

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Olezarsen Earns First-Ever FDA Approval for Familial Chylomicronemia Syndrome

HCPLive

Olezarsen ushers in a new era of care as the first therapy to receive FDA approval for adults with familial chylomicronemia syndrome as an adjunct to diet.

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Overactive cells linked to type 2 diabetes

Science Daily - Heart Disease

Researchers studied oxygen treatment as a potential therapy to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes and found no significant improvement in function in patients with type 2 diabetes.

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The FDA Hasn't Inspected This Drug Factory After 7 Recalls for the Same Flaw

Med Page Today

(MedPage Today) -- ProPublica is a Pulitzer Prize-winning investigative newsroom. Sign up for The Big Story newsletter to receive stories like this one in your inbox. The drug potassium chloride has been on the market for decades, widely prescribed.

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Drinking a moderate amount of wine may lower the risk of serious cardiovascular disease in high-risk people

Medical Xpress - Cardiology

Drinking a small or moderate amount of wine may lower the risk of serious cardiovascular disease in people at a higher risk who are following a Mediterranean diet, according to research published in the European Heart Journal.

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CagriSema Achieves 22.7% Weight Loss in Phase 3 REDEFINE 1 Trial

HCPLive

CagriSema, a fixed dose of cagrilintide 2.4 mg and semaglutide 2.4 mg, achieved statistically significant weight loss after 68 weeks versus placebo.

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First dual chamber leadless pacemaker implanted in a child

Science Daily - Heart Disease

Pediatric cardiologists have implanted a dual chamber leadless pacemaker in a child.

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Are Antibiotics Linked to Dementia? New Study Weighs In

Med Page Today

(MedPage Today) -- Antibiotic use didn't raise the risk of dementia in healthy older adults, a prospective study suggested. Over about 5 years of follow-up, antibiotic use was not tied to higher dementia incidence (HR 1.03, 95% CI 0.84-1.25) compared.

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Coughing won't save you if you're having a heart attack, despite what people claim on social media

Medical Xpress - Cardiology

A recent trend on social media has revived a curious technique from the late 1970s called cough CPR. A post claims that this method can help people, if they are alone, to survive a heart attack by coughing rhythmically to keep their heart beating. The idea is striking and dramatic, often framed as a life-saving hack, but it's not without controversy.

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Christine Frissora, MD: Vibrant System’s Role in Chronic Idiopathic Constipation Care

HCPLive

Frissora reviews findings from a cost-effectiveness analysis comparing the Vibrant System to linaclotide for CIC management.

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Which patient needs a CT scan?

Dr. Smith's ECG Blog

Which patient needs a CT Scan? Case 1: 20-something woman with chest pain Case 2: 50-something man with chest pain Case 1 A 20-something yo woman presented in the middle of the night with severe crushing chest pain. It had begun 4 hours before arrival and was initially dull, but became severe and "unbearable" 2 hours prior to arrival. She was a walk-in at triage.

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Atrial fibrillation: A review

Science Daily - Heart Disease

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.

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Injected microbubbles could be a safe way to deliver emergency oxygen

Medical Xpress - Cardiology

For years, researchers and clinicians have been trying to find a way to rapidly deliver oxygen to patients when traditional means of oxygenation are difficult or ineffective during critical moments of cardiac or respiratory arrest.

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Negative Emotionality Causes Childhood Adversity to Continue into Adulthood

HCPLive

A study shows young adults with negative emotionality, particularly alienation, who experienced childhood adversities often experience more stressful life events in adulthood.

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Chest pain and rapid pacing followed by an unexplained wide complex tachycardia. Time for cardioversion?

Dr. Smith's ECG Blog

Written by Willy Frick with edits by Ken Grauer An older man with a history of non-ischemic HFrEF s/p CRT and mild coronary artery disease presented with chest pain. He said he had had three episodes of chest pain that day while urinating. The following ECG was obtained in the emergency department during active chest pain. ECG 1 What do you think? There is a lot going on in this ECG.

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Chest Pain in a Middle-Aged Man

JAMA Cardiology

A man in his mid-50s presented with chest pain lasting 30 minutes. The initial electrocardiogram showed type A preexcitation syndrome, with obvious ST-segment depression in leads V3 through V5 and positive delta wave. What would you do next?

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Traffic noise and poverty create a dangerous cocktail for heart health

Medical Xpress - Cardiology

A new study by the German Center for Cardiovascular Research (DZHK) shows that people on low incomes who are also exposed to high levels of traffic noise have a significantly increased risk of serious cardiovascular disease. The findings highlight the need to tackle social inequalities and environmental pollution together to improve the health of disadvantaged populations.

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Brilaroxazine Shows Long-Term Efficacy in Schizophrenia in Phase 3 RECOVER

HCPLive

Efficacy and safety of brilaroxazine for schizophrenia sustained for > 1 year in open-label extension of RECOVER, announced by Reviva Pharmaceuticals.

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U.S. Deaths Are Down and Life Expectancy Is Up, but Improvements Are Slowing

Med Page Today

(MedPage Today) -- U.S. life expectancy jumped last year, and preliminary data suggest there may be another -- much smaller -- improvement this year. Death rates fell last year for almost all leading causes, notably COVID-19, heart disease.