Sat.Dec 14, 2024 - Fri.Dec 20, 2024

article thumbnail

Lifestyle Risk Factors Predict Coronary Calcification among Male Endurance Athletes

Physiologically Speaking

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. This has raised concerns that long-term, high-volume exercise might be detrimental to heart health.

article thumbnail

There are more heart attacks on Christmas than any other day of the year

Medical Xpress - Cardiology

We sing about how Christmas brings "tidings of comfort and joy," but the holiday also brings something not so "merry and bright.

article thumbnail

Cardiovascular Protection Tracks With Wine Intake, Now Provable With Urinary Marker

Med Page Today

(MedPage Today) -- Moderate wine consumption maintained its association with cardiovascular benefit when self-reports were taken out of the equation, the large PREDIMED trial showed. Using urinary tartaric acid as an objective biomarker measuring.

article thumbnail

New evidence on the relationship between moderate wine consumption and cardiovascular health

Science Daily - Stroke

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.

Diet 83
article thumbnail

The muscle stem cell case of Benjamin Button: rejuvenating muscle regenerative capacity through nutraceuticals

Journal of Clinical Investigation - Cardiology

Aging negatively affects the capacity of muscle stem cells (MuSCs) to regenerate muscle. In this issue of the JCI, Ancel, Michaud, and colleagues used a high-content imaging screen to identify nicotinamide and pyridoxine as promoters of MuSC function. The combination of the two compounds promoted MuSC function in vivo in aged mice and in primary cells isolated from older individuals.

article thumbnail

Using an AI tool, researchers find poor vascular health accelerates brain aging

Medical Xpress - Cardiology

Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.

article thumbnail

Woman Dialysis-Free After Receiving Gene-Edited Pig Kidney

Med Page Today

(MedPage Today) -- A 53-year-old woman is free from dialysis after receiving a gene-edited pig kidney transplant at NYU Langone Health, doctors announced on Tuesday. The 7-hour surgery was performed on November 25, marking the third time that.

More Trending

article thumbnail

Atrial fibrillation: A review

Science Daily - Heart Disease

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.

article thumbnail

Drinking a moderate amount of wine may lower the risk of serious cardiovascular disease in high-risk people

Medical Xpress - Cardiology

Drinking a small or moderate amount of wine may lower the risk of serious cardiovascular disease in people at a higher risk who are following a Mediterranean diet, according to research published in the European Heart Journal.

article thumbnail

Tirzepatide Officially Off FDA's Shortage List

Med Page Today

(MedPage Today) -- The shortage of the diabetes and obesity injectable tirzepatide (Mounjaro, Zepbound) has been resolved, the FDA announced Thursday. As a result, compounders will have a grace period of 60 to 90 days to wrap up production and.

Obesity 86
article thumbnail

Pediatric Food Allergies Linked to Uncontrolled Atopic Dermatitis, Long-Term Prognosis

HCPLive

Findings suggest an association between food allergies and atopic dermatitis control and persistence.

article thumbnail

Can the heart heal itself? New study says it can

Science Daily - Heart Disease

Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

article thumbnail

Traffic noise and poverty create a dangerous cocktail for heart health

Medical Xpress - Cardiology

A new study by the German Center for Cardiovascular Research (DZHK) shows that people on low incomes who are also exposed to high levels of traffic noise have a significantly increased risk of serious cardiovascular disease. The findings highlight the need to tackle social inequalities and environmental pollution together to improve the health of disadvantaged populations.

article thumbnail

Genetic predisposition to nephropathy and associated cardiovascular disease in people with type 1 diabetes: role of the angiotensinI-converting enzyme (ACE), and beyond; a narrative review

Cardiovascular Diabetology

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

64
article thumbnail

2024’s Needle-Free Approvals Transform Management of Anaphylaxis, Influenza in Children

HCPLive

Needle-free treatments, such as Neffy and FluMist, offer promising alternatives for children and adults with needle phobia, ensuring access to critical care.

article thumbnail

Coronary Subclavian Steal Syndrome

The New England Journal of Medicine

A 63-year-old man with a history of CABG presented with a 2-month history of angina during exertion of the left arm. Angiography revealed retrograde flow in the left internal thoracic artery graft (shown in a video).

Angina 68
article thumbnail

Surprising discovery pinpoints when good cholesterol becomes harmful

Medical Xpress - Cardiology

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterolhigh-density lipoproteins (HDL)may be associated with an increased prevalence of cardiovascular disease.

article thumbnail

Beyond ketosis: the search for the mechanism underlying SGLT2-inhibitor benefit continues

Journal of Clinical Investigation - Cardiology

Despite the impressive clinical benefits and widespread adoption of sodium glucose cotransporter 2 inhibitors (SGLT2i) to treat all classes of heart failure, their cardiovascular mechanisms of action are poorly understood. Proposed mechanisms range broadly and include enhanced ketogenesis, where the mild ketosis associated with SGLT2i use is presumed to be beneficial.

article thumbnail

Scientists make surprising discovery pinpointing when good cholesterol becomes harmful

Science Daily - Heart Disease

Researchers have discovered that certain components of so-called 'good' cholesterol -- high-density lipoproteins (HDL) -- may be associated with an increased prevalence of cardiovascular disease.

article thumbnail

Which patient needs a CT scan?

Dr. Smith's ECG Blog

Which patient needs a CT Scan? Case 1: 20-something woman with chest pain Case 2: 50-something man with chest pain Case 1 A 20-something yo woman presented in the middle of the night with severe crushing chest pain. It had begun 4 hours before arrival and was initially dull, but became severe and "unbearable" 2 hours prior to arrival. She was a walk-in at triage.

article thumbnail

Research suggests coffee may protect against cognitive decline in people with atrial fibrillation

Medical Xpress - Cardiology

Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association.

article thumbnail

Estimated potassium intake and major adverse cardiovascular events in individuals with type 2 diabetes: a prospective cohort study with trans-ethnic validation

Cardiovascular Diabetology

Data on the relationship between potassium intake and major cardiovascular events (MACE) in patients with diabetes are scarce. We aim to study the association between estimated potassium intake and risk of MAC.

59
article thumbnail

Overactive cells linked to type 2 diabetes

Science Daily - Heart Disease

Researchers studied oxygen treatment as a potential therapy to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes and found no significant improvement in function in patients with type 2 diabetes.

article thumbnail

Chest pain and rapid pacing followed by an unexplained wide complex tachycardia. Time for cardioversion?

Dr. Smith's ECG Blog

Written by Willy Frick with edits by Ken Grauer An older man with a history of non-ischemic HFrEF s/p CRT and mild coronary artery disease presented with chest pain. He said he had had three episodes of chest pain that day while urinating. The following ECG was obtained in the emergency department during active chest pain. ECG 1 What do you think? There is a lot going on in this ECG.

article thumbnail

Been drinking and your heart's fluttering? You may have 'holiday heart'

Medical Xpress - Cardiology

It's the time of year for workplace Christmas parties, and gatherings with family and friends. Maybe you'll drink a lot in one go.

80
article thumbnail

FDA Issues CRL for Sotagliflozin in Type 1 Diabetes and CKD

HCPLive

The FDA's decision not to approve sotagliflozin as an adjunct in T1D and CKD comes less than 2 months after a negative advisory committee meeting for the application.

article thumbnail

Best Supplements For Heart Health.

Dr. Paddy Barrett

As a cardiologist, I am frequently asked about supplements and heart health. In general, I am not a fan. Personally, I take two supplements. Whey protein for hitting my daily protein targets. Creatine for improving exercise performance and muscle mass. Neither of these supplements is for improving ‘heart health’ During the winter months, I will occasionally take vitamin D if my levels are low, but generally, if I get enough time outside, even during the winter months, I do not need t

article thumbnail

Cardiac cells and mesenchymal stem cells derived extracellular vesicles: a potential therapeutic strategy for myocardial infarction

Frontiers in Cardiovascular Medicine

Despite improvements in clinical outcomes of acute myocardial infarction (AMI), mortality rates remain high, indicating the need for further understanding of the pathogenesis and developing more effective cardiac protection strategies. Extracellular vesicles (EVs) carry proteins and noncoding RNAs (ncRNAs) derived from different cardiac cell populations, mainly including cardiomyocytes, endothelial cells, endothelial progenitor cells, cardiac progenitor cells, cardiosphere-derived cells, immune

article thumbnail

First dual chamber leadless pacemaker implanted in a child

Medical Xpress - Cardiology

UC Davis Director of Pediatric Electrophysiology Dan Cortez has set another world record: He is the first to implant a dual chamber leadless pacemaker in a child. His case report was published this week in the journal Pacing and Clinical Electrophysiology.

article thumbnail

FDA Approves Tirzepatide for Obstructive Sleep Apnea in Obesity

HCPLive

Tirzepatide's approval marks the first and only prescription medicine available for adults with moderate-to-severe obstructive sleep apnea and obesity.

Obesity 59
article thumbnail

Keeping Your Heart Healthy Through the Holidays and Into the New Year

AMS Cardiology

The magic of the holidays often comes with hidden challenges for our hearts. Rich foods, packed calendars, and holiday pressures can derail even our best health intentions. Yet maintaining heart health doesn’t mean sacrificing the festivities. Simple, mindful choices during the holiday season can protect your cardiovascular health and lay the foundation for a lively year ahead.

article thumbnail

Elucidating the neural mechanisms of stress-induced cardiovascular responses

Science Daily - Heart Disease

The lateral habenula is a brain region associated with behavioral changes and autonomic responses during psychological stress. Researchers at the University of Tsukuba have identified the involvement of the dopaminergic system in the cardiovascular responses triggered by neuronal excitation in the lateral habenula. They further determined that the ventral tegmental area of the midbrain, which is the origin of dopamine neurons, plays a mediating role in this response.

article thumbnail

Old wisdom meets new tech: Traditional Chinese medicine inspires pulse sensors

Medical Xpress - Cardiology

Continuously monitoring a person's pulse can provide meaningful medical information, such as heart rate and, indirectly, blood pressure. However, pulse waves can vary dramatically from person to person and even within the same person at different times of day and during different activities. These variations make it difficult for current wearable pulse sensors to accurately record useful data, which is especially problematic for those with cardiovascular disease or high-risk factors for those di

article thumbnail

Study Highlights Necessity of Image Quality for Deep Learning Model Diagnostic Success

HCPLive

These data resulted from an investigation of the effect of varying image qualities on the diagnostic abilities of a convolutional neural network (CNN) model and clinicians.

59
article thumbnail

Metabolomic studies reveal and validate potential biomarkers of diabetic retinopathy in two Chinese datasets with type 2 diabetes: a cross-sectional study

Cardiovascular Diabetology

Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus and causes vision impairment and blindness. The presence of major risk factors for DR, such as high levels of HbA1c, does no.

article thumbnail

Dyslipidemia and associated factors among adult type two diabetes mellitus patients in Felege Hiywot Refral, Hospital, Bahir Dar, Ethiopia, 2023

Frontiers in Cardiovascular Medicine

BackgroundDyslipidemia is a common condition in type two diabetic patients, and it is thought to have a significant role in moderating the cardiovascular risk associated with diabetes. Data on serum lipid profiles in type 2 diabetes patients from Bahir Dar, Ethiopia is limited. This study aimed to evaluate the prevalence of dyslipidemia among adult type 2 diabetes patients and to explore potential contributing factors.Method and materialsA facility-based cross-sectional study was conducted with

article thumbnail

Largest study to date shows 39 weeks best for hypertensive pregnancies

Medical Xpress - Cardiology

A collaborative study from physician researchers at the University of Cincinnati College of Medicine is shining new light on current guidelines for delivery timing in pregnant mothers with chronic hypertension.