Sat.Dec 23, 2023 - Fri.Dec 29, 2023

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ECG Blog #410 — How Tall are the T Waves?

Ken Grauer, MD

QUESTION: HOW would YOU interpret the ECG in Figure-1 — if no clinical information was provided? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ). = The H ISTORY in T oday's C ASE: The patient in today's case is a teenager who presented to the ED ( E mergency D epartment ) in cardiac arrest after electrocution.

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Young-Onset Dementia Tied to New Risk Factors

Med Page Today

(MedPage Today) -- Four new risk factors for young-onset dementia were identified in the prospective U.K. Biobank study. Orthostatic hypotension, vitamin D deficiency, high C-reactive protein (CRP) levels, and social isolation emerged as new risk.

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A study of genetics of pericarditis increases understanding of newly approved drug treatment

Medical Xpress - Cardiology

Sequence variants that protect against pericarditis have been discovered at a genomic locus encoding interleukin-1 immune cytokines. A newly approved drug treatment for pericarditis inhibits these cytokines, according to a new study.

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A young woman with palpitations. What med is she on? With what medication is she non-compliant? What management?

Dr. Smith's ECG Blog

Written by Pendell Meyers A woman in her 20s with connective tissue disorder and history of aortic root and valve repair presented with palpitations. Here is her triage ECG: What do you think? Atrial flutter with 2:1 conduction. The atrial flutter rate is approximately 200 bpm, with 2:1 AV conduction resulting in ventricular rate almost exactly 100 bpm.

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ECG Blog #409 — Every-Other-Beat.

Ken Grauer, MD

The ECG in Figure-1 — was obtained from a patient with palpitations. The patient was hemodynamically stable in association with this rhythm. QUESTIONS: What is the rhythm in Figure-1 ? — How certain are you of your answer? — Why is QRS morphology changing ? Figure-1: The initial ECG in today's case. My Interpretation of the ECG in Figure-1: Since the patient is hemodynamically stable — there is time for systematic assessment of the rhythm.

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Food as Diabetes Medicine? Maybe Not, Trial Suggests

Med Page Today

(MedPage Today) -- An intensive food-as-medicine program didn't improve glycemic control in adults with type 2 diabetes any better than usual care in a randomized clinical trial. After 6 months, both groups had a similar drop in HbA1c -- 1.5.

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Physiology Friday #198: The Anabolic Response to Postexercise Protein Intake Has "No Upper Limit"

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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What’s wrong with the NHS? – part five

Dr. Malcolm Kendrick

29th December 2023 The underlying forces In the last few blogs, I have been writing about the proliferation of guidelines, targets, and regulatory work in the NHS. Hopefully I have managed to give you a sense of how much time and effort these pile on to everyday work. Time and effort which eats away at clinical time, erodes morale and drives down productivity.

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Deep Flaws in FDA's Device Oversight, and Patient Harm, Exposed in Lawsuits, Records

Med Page Today

(MedPage Today) -- Living with diabetes, Carlton "PeeWee" Gautney Jr. relied on a digital device about the size of a deck of playing cards to pump insulin into his bloodstream. The pump, manufactured by device maker Medtronic, connected plastic.

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Boston Scientific Initiates AVANT GUARD Clinical Trial to Evaluate FARAPULSE Pulsed Field Ablation System as First-Line Treatment for Persistent Atrial Fibrillation

DAIC

milla1cf Fri, 12/29/2023 - 09:39 December 29, 2023 — Boston Scientific Corporation has initiated the AVANT GUARD clinical trial to evaluate the safety and effectiveness of the FARAPULSE Pulsed Field Ablation (PFA) System* as a first-line treatment for persistent atrial fibrillation (AF), the only trial to study the use of PFA as frontline therapy in patients with this form of AF.

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New Secure Image Sharing Technology: Save Time and Reduce Costs

NOVARAD

Healthcare organizations are always looking for ways to save time and money while providing quality patient care. As innovative technology emerges, new secure image-sharing technology that maximizes time and reduces costs has taken the forefront of data mobility.

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Instructors' Collection: Acute Anterior-lateral STEMI

ECG Guru

The Patient: A 60-year-old man at work. He experienced a sudden onset of substernal chest pain, nausea & vomiting, and dizziness. He states the pain is a 5 on 1-10 scale. No cardiac history or current medications. The ECGs: The first ECG , taken at 12:30:05, shows a sinus rhythm with ventricular bigeminy. In some leads, you can see the sinus P waves hidden in the beginnings of the PVCs, so we know the underlying sinus rhythm is about 82 bpm.

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DAPT Stays Helpful for Minor Stroke Even With Later Presentation, Worse Symptoms

Med Page Today

(MedPage Today) -- The benefit of dual antiplatelet therapy (DAPT) for a minor ischemic stroke seems to apply outside the 24-hour time window and minimal stroke symptoms for which the treatment is currently recommended, based on results from the.

Stroke 126
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Butterfly Network Announces Commercial Agreement with Mendaera for Next-Generation Interventional Robotic System Powered by Butterfly's Ultrasound-on-Chip Technology

DAIC

milla1cf Wed, 12/27/2023 - 20:11 December 27, 2023 — Butterfly Network, Inc. , a digital health company transforming care through the power of portable, semiconductor-based ultrasound technology and intuitive software, and Mendaera , a Silicon Valley-based company developing technology to help healthcare providers more easily and confidently perform procedures through the power of medical robotics, today announced an agreement to commercialize a novel robotic system that is Powered by Butterf

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Wearable Biosensors Predicts Aggressive Behaviors in Autism, Study Finds

HCPLive

After participants with autism wore biosensors tracking physiological signals, a logistic regression predicted aggressive behaviors 3 minutes before it happened.

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Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission

JAMA Cardiology

This secondary analysis of the Safety, Tolerability, and Efficacy of Rapid Optimization, Helped by N-Terminal Pro–Brain Natriuretic Peptide Testing of Heart Failure Therapies (STRONG-HF) randomized clinical trial investigates what variables are associated with success in uptitration of guideline-directed medical therapy after hospital discharge for an acute heart failure admission.

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Bernie Sanders Has COVID; Global Fake Ozempic Problem; Nitazenes, the New Fentanyl?

Med Page Today

(MedPage Today) -- Some links may require registration or subscription. Please note that in observance of the upcoming holiday, Morning Break will not publish on New Year's Day and will resume Tuesday, January 2. Sen. Bernie Sanders (I-Vt.), 82.

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Ohio State's Heart and Vascular Center Names 2023 Schottenstein Prize Laureate

DAIC

Richard Kitsis, MD milla1cf Wed, 12/27/2023 - 20:39 December 27, 2023 — The Ohio State University Wexner Medical Center ’s Heart and Vascular Center has named Richard Kitsis, MD , professor of medicine and cell biology at the Albert Einstein College of Medicine in New York City, as recipient of the 2023 Jay and Jeanie Schottenstein Prize in Cardiovascular Sciences.

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Major breakthrough in hypertension diagnosis could save billions

Medical Xpress - Cardiology

Hunter Medical Research Institute and University of Newcastle researcher Professor Murray Cairns, along with his Precision Medicine team, have discovered a way of predicting who will respond to blood pressure treatments to lower sodium in the body. Their findings were published this week in Circulation.

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Stacie Bell, PhD: The Effect of Cognitive Impairment on Daily Life in Patients with SLE

HCPLive

Stacie Bell, PhD, emphasizes the importance of collaborative or multidisciplinary care in patients with SLE.

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No Improved Outcomes for HF Patients With Sleep Apnea Using ASV Breathing Devices

Med Page Today

(MedPage Today) -- Breathing machines with adaptive servo-ventilation (ASV) did not improve survival or other clinical outcomes in patients with heart failure (HF) and reduced ejection fraction and sleep-disordered breathing, the phase III ADVENT.

Outcomes 115
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Baptist Health Lexington Enhances 20-Year Leadership in Pioneering Advanced Robotic Technology for Heart Disease Patients

DAIC

milla1cf Wed, 12/27/2023 - 20:31 December 27, 2023 — Stereotaxis , a pioneer in surgical robotics for minimally invasive endovascular intervention, and Baptist Health Lexington , a leading health provider in Kentucky, announced that physicians have built upon their two-decades of leadership in robotic heart care with the successful treatment of first patients using the newest advancement in the technology, the Genesis Robotic Magnetic Navigation (RMN) System.

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5 Health Metrics To Consider In The New Year

Dr. Paddy Barrett

New Year. New You. At this time every year, billions of people likely begin their health journey. Rather than just aiming to get ‘Healthy’ this year, how about setting clear targets for improvement that are highly correlated to positive health outcomes? Here are five powerful metrics you can assess in the New Year to see where you stack up and where you might need to make some improvements.

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“Heart Failure: it’s time to finally change the F-word”: my Editorial in BMJ Open Heart

Heart Sisters

I had the impression throughout the past year that it's clearly unusual for the British Medical Journal (BMJ) to invite a heart patient (who is not a doctor, a researcher or an academic) to write an Editorial for BMJ Open Heart - but it's just been published!!

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Stacie Bell, PhD: Adverse Childhood Experiences in Pediatric SLE

HCPLive

Stacie Bell, PhD, highlights the lasting effects of childhood adversities in patients with pediatric lupus.

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Oral Factor XIa Inhibitor Disappoints for Secondary Stroke Prevention

Med Page Today

(MedPage Today) -- Factor XIa inhibitor milvexian did not provide meaningful secondary prevention over dual antiplatelet therapy for stroke survivors, the phase II trial AXIOMATIC-SSP found. In patients with recent ischemic stroke or transient.

Stroke 98
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Digoxin shows promise in enhancing post-surgery survival for infants with certain heart defects

Medical Xpress - Cardiology

A strong, rhythmic pulse is a lifelong companion for those with a healthy heart. But for about 1% of babies born in the U.S. every year, developmental heart problems compromise that steady beat.

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An elderly patient with stuttering chest pain. Don't jump to conclusions.

Dr. Smith's ECG Blog

I was reading ECGs on the system and saw this one, and instantly knew the probable ECG diagnosis: What do you think? I went to the patient's chart: Elderly woman with stuttering chest pain and SOB, and dizziness. What do you think now? This is a very typical ECG for Hypertrophic Cardiomyopathy. I sent it to our EKG Nerdz group and Jesse McLaren replied: "Apical HOCM" It reminded me of many other cases I have seen, such as this one: Left Bundle Branch Block with Less Than 1 mm of Concordant ST El

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Diabetes Dialogue: Key Updates in ADA Standards of Care—2024

HCPLive

Hosts discuss what they consider the most significant or relevant updates in the ADA's Standards of Care—2024, with a focus on new recommendations for glycemic management, bone health, immunizations, and weight management.

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Mechanical Versus Bioprosthetic Aortic Valve Replacement in Patients Undergoing Bentall Procedure

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundThe widely used Bentall procedure is the criterion standard treatment for aortic root pathology. Studies comparing the long‐term outcomes of bioprosthetic and mechanical valves in patients undergoing the Bentall procedure are limited.Methods and ResultsPatients who underwent the Bentall procedure with a bioprosthetic or mechanical valve between 2001 and 2018 were identified from Taiwan's National Health Insurance Research Datab

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Nuclear Tracer Shortage; Weighing Post-Ablation OAC; Fix for Biased AI Tools?

Med Page Today

(MedPage Today) -- Magnesium's hemostatic effects in intracerebral hemorrhage were supported by reduced hematoma expansion in FAST-MAG participants who achieved higher serum magnesium levels with magnesium treatment. (Stroke) The American Society.

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Expecting? Stay heart-healthy for you and your baby

Medical Xpress - Cardiology

It's never too late for an expectant mom to adopt healthy habits for her baby and herself.

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Cytokinetics Announces Positive Topline Data for Aficamten in SEQUOIA-HCM

HCPLive

On December 27, 2023, Cytokinetics announced positive topline results from the phase 3 SEQUOIA-HCM trial evaluating aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy

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Cardiovascular Risk Stratification of Patients Undergoing Hematopoietic Stem Cell Transplantation: The CARE?BMT Risk Score

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundEvidence guiding the pre‐hematopoietic stem cell transplantation (HSCT) cardiovascular evaluation is limited. We sought to derive and validate a pre‐HSCT score for the cardiovascular risk stratification of HSCT candidates.Methods and ResultsWe leveraged the CARE‐BMT (Cardiovascular Registry in Bone Marrow Transplantation) study, a contemporary multicenter observational study of adult patients who underwent autologous or allogen

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50-year old with chest pain, “no ischemic changes”

Dr. Smith's ECG Blog

Written by Jesse McLaren A previously healthy 50 year-old presented with 24 hours of intermittent exertional chest pain, radiating to the arms and associated with shortness of breath. It was ongoing on arrival in the emergency department. Below is the old ECG (on top) and then new ECG (on bottom). What do you think? There is normal sinus rhythm, normal conduction, normal axis, and tall precordial voltages with J waves from early repolarization.

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Impact of Transjugular Intracardiac Echocardiography-Guided Self-Expandable Transcatheter Aortic Valve Implantation on Reduction of Conduction Disturbances

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:A high permanent pacemaker implantation (PPI) risk remains a concern of self-expandable transcatheter aortic valve implantation, despite the continued improvements in implantation methodology. We aimed to assess the impact of real-time direct visualization of the membranous septum using transjugular intracardiac echocardiography (ICE) during transcatheter aortic valve implantation on reducing the rates of conduction disturbanc

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Association Between Delays in Time to Bystander CPR and Survival for Witnessed Cardiac Arrest in the United States

Circulation: Cardiovascular Quality & Outcomes

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:Prompt initiation of bystander cardiopulmonary resuscitation (CPR) is critical to survival for out-of-hospital cardiac arrest (OHCA). However, the association between delays in bystander CPR and OHCA survival is poorly understood.Methods:In this observational study using a nationally representative US registry, we identified patients who received bystander CPR from a layperson for a witnessed OHCA from 2013 to 2021.