Sat.Nov 23, 2024 - Fri.Nov 29, 2024

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Irregular sleep-wake cycle linked to heightened risk of major cardiovascular events

Medical Xpress - Cardiology

An irregular sleep-wake cycle is associated with a heightened risk of major cardiovascular events, such as heart attack and stroke, even for those who clock up the recommended nightly hours of shut-eye, finds research published online in the Journal of Epidemiology & Community Health.

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What makes a T-wave Hyperacute? And: 30 Examples of Hyperacute T-waves, 10 in each of 3 myocardial territories.

Dr. Smith's ECG Blog

Pendell and I and the geniuses at Powerful Medical (Producers of the PMCardio Queen of Hearts OMI AI app ) are working on an objective, mathematical definition of hyperacute T-waves , based on real OMI outcomes and hyperacute T-wave annotation that has excellent interrater agreement (between me and Pendell), and it will end up being a logistic regression using these 3 variables: 1) area under the curve (AUC) relative to the QRS size 2) increased symmetry , as defined by time from T-wave onset to

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Alexei Grom, MD: Exploring Safer Treatment Options for Refractory Macrophage Activation Syndrome

HCPLive

Emapalumab may improve outcomes in patients with MAS whose disease didn’t respond to steroid therapy and mitigate the need for more toxic therapies.

Outcomes 118
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Risk of heart problems persists years after COVID infection: 4 study findings

Becker's Hospital Review - Cardiology

A recent study using data from the UK BioBank highlighted the extended risk of major adverse cardiac events in individuals who have recovered from COVID-19.

COVID-19 115
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Men at high risk of cardiovascular disease face brain health decline 10 years earlier than women, study finds

Medical Xpress - Cardiology

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier—from their mid 50s to mid 70s—than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

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Muvalaplin Aces Phase 2 Lp(a) Test

CardiacWire

Impressive results from the Phase 2 KRAKEN trial presented at the AHA 2024 Scientific Sessions showed that Eli Lilly’s muvalaplin greatly reduces Lp(a) blood levels, adding an attractive oral option to its Lp(a) pipeline. High Lp(a) is an inherited CVD risk factor that impacts one out of every five people and currently has no approved drug therapies.

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Vitamin D Deficiency More Common in Lupus Nephritis Than Lupus Without Kidney Disease

HCPLive

Hypovitaminosis D was more prevalent in patients with lupus nephritis compared to patients with systemic lupus erythematosus without kidney disease.

More Trending

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Gene-screening method identifies cause of heart cell damage from chemotherapy

Medical Xpress - Cardiology

Using a gene-screening method they created, Stanford Medicine researchers may have discovered why an effective chemotherapy damages heart cells—and they have identified a drug that could keep the heart cells beating.

Research 109
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Top hospitals for cardiac care: Healthgrades

Becker's Hospital Review - Cardiology

Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those, 97 hospitals were recognized for delivering superior clinical outcomes in cardiac care for heart bypass surgery, coronary interventional procedures, heart attack treatment, heart failure treatment and heart valve surgery.

Hospital 105
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Link Identified Between Obesity, Inflammatory Skin Diseases Such as Psoriasis

HCPLive

The investigators of this study noted an association between obesity and conditions such as rosacea, psoriasis, and lichen simplex chronicus.

Obesity 114
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Popular diabetes and obesity drugs also protect kidneys, study shows

Science Daily - Heart Disease

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.

Diabetes 106
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Certain hormone replacement therapy tablets linked to increased heart disease and blood clot risk

Medical Xpress - Cardiology

Certain hormone replacement therapy (HRT) tablets containing both estrogen and progestogen are associated with a higher risk of heart disease and rare but serious blood clots known as venous thromboembolism (VTE) in women around the age of menopause, finds a study from Sweden published in The BMJ today.

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Long-Term Aspirin vs Clopidogrel After Coronary Stenting by Bleeding Risk and Procedural Complexity

JAMA Cardiology

This study compares clopidogrel vs aspirin monotherapy in patients with high bleeding risk and/or percutaneous coronary intervention complexity.

Stents 105
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FDA Accepts Alnylam’s sNDA for Vutrisiran for ATTR-CM

HCPLive

The FDA set the Prescription Drug User Fee Act (PDUFA) date for the investigational RNAi therapeutic as March 23, 2025.

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The link between sleep and blood pressure: New research sheds light on gender differences

Science Daily - Heart Disease

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders -- strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in one gender over the other, especially as it relates to the heart.

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Review highlights racial disparities in sudden cardiac arrest and death among athletes

Medical Xpress - Cardiology

A recent major review of data published by The Lancet and led by Emory sports cardiologist Jonathan Kim, MD, shows that Black athletes are approximately five times more likely to experience sudden cardiac arrest (SCA) and sudden cardiac death (SCD) compared to white athletes, despite some evidence of a decline in rates of SCD overall. SCA and SCD have historically been a leading cause of mortality among athletes, particularly those involved in high-intensity sports.

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ASCVD Mortality Linked to Specific Air Pollution Sources

Med Page Today

(MedPage Today) -- The relationship between air pollution and cardiovascular harm was supported by another study, this time down to the level of specific types of pollution that appeared to have varying effects according to geographical region.

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Novel Quality Index Linked to Reduced Hospital Admissions for Gout

HCPLive

The Urate-Lowering Therapy to Acute Treatment Ratio (ULTrA) was linked to fewer gout-related hospital admissions.

Hospital 111
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Emory hospital 1st in US to transplant magnet heart pump

Becker's Hospital Review - Cardiology

An Atlanta-based Emory University Hospital team became the first in the U.S. to perform a surgical implantation of magnetically levitated ventricular assist device.

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The link between sleep and blood pressure: New research sheds light on gender differences

Medical Xpress - Cardiology

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders—strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in one gender over the other, especially as it relates to the heart.

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Brain Volume Changes Come 10 Years Sooner for Men With Cardiovascular Risks

Med Page Today

(MedPage Today) -- Men at high risk of cardiovascular disease had brain volume changes a decade earlier than women, U.K. Biobank data showed. Cardiovascular risk and obesity had the strongest relationship with lower gray matter volume in men between.

Obesity 96
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Schizophrenia with Violence Linked to Reduced Left Frontal Gray Matter, Higher TSH

HCPLive

A study found patients with schizophrenia exhibiting violence, vs. those who don’t, have less gray matter volume in the frontal lobe and greater thyroid-stimulating hormone levels.

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What Should Your Blood Pressure Be?

Dr. Paddy Barrett

“What should my blood pressure be?” This is one of the most common questions I get as a cardiologist. The answer is pretty simple, but most people get this wrong, and doing so increases their future risk of heart attack and strokes. The problem is that high blood pressure is not some obscure risk that only impacts a small percentage of the population.

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Different menopausal hormone treatments pose different risks

Science Daily - Heart Disease

Researchers have analysed the effects of seven different hormone treatments for menopausal symptoms on the risk of blood clots, stroke and heart attack. The study, which involved around one million women aged between 50 and 58, is the largest and most comprehensive study of currently prescribed hormonal substances in the world. The results show that the risks differ depending on the active substance and how the medicine is taken.

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Many Drinkers Cut Back After Starting Obesity Meds, Study Finds

Med Page Today

(MedPage Today) -- Nearly half of participants in a weight-loss program who consumed alcohol at baseline began drinking less after adding an obesity drug into their weight-management regimen, a cohort study indicated. Among the 7,491 participants.

Obesity 87
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Meta-Analysis Supports Potential Use of Ketamine for PTSD, OCD

HCPLive

A recent study suggests ketamine can significantly improve symptoms of PTSD and OCD—but this is based on a review of an insufficient number of randomized controlled trials.

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Research shows death rates linked to obesity-related heart disease are up, especially among men

Medical Xpress - Cardiology

The rate of deaths from ischemic heart disease related to obesity nearly tripled in the U.S. over a two-decade span, according to new research. The rate for men more than tripled.

Obesity 84
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A simplified cardiac implantable electronic device infection classification by combining key diagnostic criteria.

HeartRhythm

Cardiac implantable electronic device (CIED) infection still lacks standardized and universally accepted diagnostic criteria. Current EHRA criteria1 largely adapt to CIED Infections the Modified Duke criteria2 and ESC 2015 criteria,3 which were developed for native valve endocarditis and later adapted to prosthetic valve endocarditis.

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Hunting & Heart Attacks; Cardiologist's Whistleblower Suit; Algorithm Predicts Death

Med Page Today

(MedPage Today) -- The American Heart Association said that hunters should be advised that physical exertion, colder temperatures, and the thrill of the hunt can put them at risk for heart attack or stroke. Merck announced positive topline results.

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Can Antipsychotics Increase Mortality Risk? A New Study Shows It Might

HCPLive

A study showed high-dose antipsychotics and benzodiazepines were linked to an increased mortality risk for those with schizophrenia. High-dose antidepressants lowered the risk.

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World's most common heart valve disease linked to insulin resistance

Medical Xpress - Cardiology

A large population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world's most common heart valve disease—aortic stenosis (AS).

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Healing the gut can reduce long-term impact of stroke

Science Daily - Stroke

Healing the gut may be the key to improving long-term recovery in stroke patients, scientists have found. The latest of multiple studies highlights the potential of this novel avenue of treatment, which takes advantage of the link between the brain and digestive system to curb cognitive impairment and other lingering impacts of a stroke or brain trauma.

Strokes 76
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How best to describe the location of the substrates for abnormal cardiac rhythms

HeartRhythm

Although he is widely believed to have stated “and still it moves,” there is no documentary evidence that Galileo Galilei uttered these words subsequent to his forced retraction of his notion that the earth moved round the sun. His alleged statement, nonetheless, stated an obvious fact, which was eventually supported by evidence. Nowadays, we allegedly practice evidence-based medicine.

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Impact of IgAN on Quality of Life

HCPLive

Panelists discuss how IgA nephropathy affects patients’ quality of life, addressing both the physical symptoms and the emotional challenges associated with the condition.

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Researchers reprogram skin cells to create human-compatible pig heart valve

Medical Xpress - Cardiology

Human skin cells have been reprogrammed into heart valve cells and then used to successfully transplant a pig heart valve into a rodent, led by the research of a Northeastern University professor.

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Consensus on Platelet Function and Genetic Testing in PCI: Key Points

American College of Cardiology

The following are key points to remember from a 2024 updated international consensus statement on platelet function and genetic testing in percutaneous coronary intervention (PCI).

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Managing Drug-Drug Interactions with Mavacamten: a Focus on Combined Use of Anti-Arrhythmic Drugs and Anticoagulants

HeartRhythm

Mavacamten is a selective, allosteric, and reversible cardiac myosin inhibitor, representing the first disease-specific treatment for obstructive hypertrophic cardiomyopathy (HCM) that targets the core pathophysiological mechanism of this condition. Clinical evidence supports its efficacy in improving symptoms, cardiac function and remodeling, thereby supplementing established treatment regimes.