Med Page Today
AUGUST 5, 2024
(MedPage Today) -- PHILADELPHIA -- Coffee and tea intake were associated with long-term cognitive changes in older adults, two prospective studies presented at the Alzheimer's Association International Conference (AAIC) suggested. Among 6,001.
Science Daily - Heart Disease
AUGUST 7, 2024
Lab-grown organs are a long-time 'holy grail' of organ engineering that has yet to be achieved, but new research has brought that goal a big step closer to reality using a new 3D-printing method called co-SWIFT. co-SWIFT prints branching networks of double-layered vessels that are infused with smooth muscle cells and endothelial cells into living human cardiac tissue, and can even replicate patient-specific vascular structures,indicating that it could one day be used for personalized medicine.
Ken Grauer, MD
AUGUST 8, 2024
I was sent the ECG shown in Figure-1 — told only that that this middle-aged woman noted chest tightness and nausea an hour earlier. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? — IF told that this patient arrested shortly after ECG #1 — Does this change your interpretation? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original EC G using PMcardio ).
HCPLive
AUGUST 9, 2024
The FDA approved epinephrine nasal spray (Neffy) for the emergency treatment of allergic reactions, including anaphylaxis, in adult and pediatric patients who weigh at least 30 kg.
Med Page Today
AUGUST 4, 2024
(MedPage Today) -- PHILADELPHIA -- Intermittent calorie restriction improved executive function and memory measures in cognitively intact older adults, an exploratory pilot study suggested. The 8-week randomized clinical trial of 40 overweight.
Nature Reviews - Cardiology
AUGUST 6, 2024
Nature Reviews Cardiology, Published online: 07 August 2024; doi:10.1038/s41569-024-01064-4 In this Review, Ghofrani and colleagues discuss the mechanisms underlying the development of pulmonary arterial hypertension, provide an overview of approved therapies and describe the predominantly non-vasodilatory drugs that are currently being tested in clinical trials.
Cardiology Update
AUGUST 4, 2024
Despite proven benefits in reducing morbidity and mortality, many heart failure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). The 2021 European Society of Cardiology guidelines recommend guideline-directed medical therapy (GDMT) for patients with HF with reduced ejection fraction (HFrEF). This includes beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, and SGLT2 inhibitors.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Med Page Today
AUGUST 5, 2024
(MedPage Today) -- The biggest risks for organ damage for patients with systemic lupus erythematosus (SLE) come in the first year after diagnosis, analysis of a long-running registry indicated. Among 1,274 members of a large Spanish SLE cohort.
Science Daily - Heart Disease
AUGUST 6, 2024
Doctors recommend making fruits and vegetables a foundational part of the treatment of patients with hypertension. Diets high in fruits and vegetables are found to lower blood pressure, reduce cardiovascular risk, and improve kidney health due to their base-producing effects. A new study details the findings from a five-year interventional randomized control trial.
Dr. Paddy Barrett
AUGUST 9, 2024
More than heart disease or cancer, the risk of dementia often creates much greater anxiety in the patients I see. And given that dementia is routinely in the top 5 leading causes of death, this concern is dually warranted. But can dementia be prevented? The answer is yes. But as I have said many, many times in the past, we need to understand that prevention is usually a shorthand way of saying: “Decrease the odds of something early in life” The reason for this is that when it comes t
HCPLive
AUGUST 5, 2024
On August 05, 2024, less than a month prior to its presentation at ESC 24, Bayter has announced topline data from the FINEARTS-HF trial indicating finerenone met the primary endpoint.
Med Page Today
AUGUST 5, 2024
(MedPage Today) -- A qualitative study of semaglutide (Ozempic, Wegovy) purchases over the internet without a prescription uncovered scams, low purity levels, and possible contamination of products. Quality testing of semaglutide products purchased.
Science Daily - Heart Disease
AUGUST 8, 2024
Significant improvements in aerobic fitness were noted after 12 weeks of high-intensity interval training sessions compared to traditional, moderate exercise sessions, according to a new study.
Cardiovascular Diabetology
AUGUST 6, 2024
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronary artery disease (CAD). Research design and methods All patients with diabetes and CAD undergoing a coronary angiography between 2010 and 2021 according to the Swedish Angiography and Angioplasty Registry were included. Information on GLD (dispended 6 months before or after coronary angiography) was collected from the Swedish Prescribed Drug Registry.
HCPLive
AUGUST 9, 2024
Findings from a prespecified secondary analysis of the reduced-dose cohort of the TESTING trial suggest the efficacy of a lower dose of oral methylprednisolone in IgA nephropathy.
Med Page Today
AUGUST 6, 2024
(MedPage Today) -- Poor physical function appeared to be the primary reason for increased fracture risk in older women with type 2 diabetes, a prospective observational study suggested. According to Mattias Lorentzon, MD, PhD, of Sahlgrenska University.
Science Daily - Heart Disease
AUGUST 7, 2024
A cardiovascular health construct based on the American Heart Association's Life's Essential 8 but enhanced with a ninth psychological health metric strongly predicts all-cause and cardiovascular mortality.
Frontiers in Cardiovascular Medicine
AUGUST 7, 2024
Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades. However, with the compelling evidence on the safety and efficacy of transcatheter aortic valve replacement (TAVR), it has become the gold standard treatment option for many patients with symptomatic severe AS.
HCPLive
AUGUST 8, 2024
Treatment with GLP-1 RAs led to improvements in weight loss, liver function tests, and liver fat in patients with diabetes and MASLD, with hepatic improvements independent of weight loss.
Dr. Smith's ECG Blog
AUGUST 4, 2024
Written by Pendell Meyers Try first to interpret the ECG without any clinical context: What do you think? Sinus rhythm with abnormal STE in V2-V6, and I, II, aVF. Reciprocal STD in aVR and V1. Most leads with STE have remarkably non-hyperacute, flat T waves. Most would say that there is Spodick's sign. The PR depression in II (and its reciprocal PR elevation in aVR) is probably beyond normal baseline values.
Med Page Today
AUGUST 5, 2024
(MedPage Today) -- Note that some links may require registration or subscription. Rock band Aerosmith announced its retirement, saying that a full recovery of singer Steven Tyler's vocal injury does not appear possible. (People) Belgium withdrew.
Heart Sisters
AUGUST 4, 2024
"People often believe that their 'silent' heart attack is something else - like the flu or a pulled muscle. Much later, when they end up getting diagnosed with a heart attack that they didn't know they were having, they might recall an episode of feeling vaguely unwell." - Dr.
HCPLive
AUGUST 7, 2024
These data point to differences between genders such as time to initiation of treatment, treatment choice, response to medication, adverse events, and adherence.
Dr. Smith's ECG Blog
AUGUST 9, 2024
Written by Colin Jenkins and Nhu-Nguyen Le with edits by Willy Frick and by Smith A 46-year-old male presented to the emergency department with 2 days of heavy substernal chest pain and nausea. He reported a history of “Wolf-Parkinson-White” and “heart attack” but said neither had been treated. These diagnoses were not found in his medical records nor even a baseline ECG.
JAMA Cardiology
AUGUST 6, 2024
This secondary analysis of the Valsartan in Acute Myocardial Infarction (VALIANT) and Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI (PARADISE-MI) randomized clinical trials investigates the changes over time in sudden death rate after myocardial infarction and the characteristics of people dying suddenly.
Circulation
AUGUST 4, 2024
Circulation, Volume 150, Issue 6 , Page 488-503, August 6, 2024. The pro- and antiarrhythmic effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been extensively studied in preclinical and human trials. Despite early evidence of an antiarrhythmic role of n-3 PUFA in the prevention of sudden cardiac death and postoperative and persistent atrial fibrillation (AF), subsequent well-designed randomized trials have largely not shown an antiarrhythmic benefit.
HCPLive
AUGUST 6, 2024
A recent study found a high prevalence of head injuries among law enforcement officers may make them more prone to experiencing mental health issues.
Dr. Smith's ECG Blog
AUGUST 6, 2024
Written by Magnus Nossen with Edits by Grauer and Smith The ECGs in today’s case are from 3 different patients all presenting with new-onset CP ( Chest Pain ). All ECGs were recorded by EMS, and transferred to a PCI capable center for evaluation. For 2 of the 3 patients — the cath lab was activated based on the ECG. One of the patients was lucky to have expert ECG interpretation by the Queen Of Hearts AI model.
Hypertension Journal
AUGUST 5, 2024
Hypertension, Ahead of Print. Hypertension is a leading risk factor for cardiovascular morbidity and mortality. Despite the widespread availability of both pharmacological and lifestyle therapeutic options, blood pressure control rates across the globe are worsening. In fact, only 23% of individuals with high blood pressure in the United States achieve treatment goals.
American College of Cardiology
AUGUST 6, 2024
What is the degree to which patients newly diagnosed with heart failure with reduced ejection fraction (HFrEF) are eligible for quadruple medical therapy, and what are the projected benefits of in-hospital initiation?
HCPLive
AUGUST 4, 2024
A year after zuranolone’s FDA approval for postpartum depression on August 3, 2023, prescribers and a patient weigh in about the medication’s success in alleviating symptoms.
Becker's Hospital Review - Cardiology
AUGUST 9, 2024
The American College of Cardiology has updated care guidelines for patients hospitalized with heart failure, according to an Aug. 8 report published in the Journal of the American College of Cardiology.
Physiologically Speaking
AUGUST 9, 2024
Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
The New England Journal of Medicine
AUGUST 7, 2024
A patient with serious thrombotic episodes was found to have a monoclonal gammopathy of an anti–PF4 antibody. Myeloma therapy reduced the paraprotein level and prevented further thrombotic events.
HCPLive
AUGUST 5, 2024
Ocugen will initiate expanded access to OCU400 gene therapy in adults with retinitis pigmentosa prior to BLA approval.
Becker's Hospital Review - Cardiology
AUGUST 5, 2024
In September, Miami Transplant Institute named Hari Mallidi, MD, chief of cardiac surgery and program director of heart transplantation and mechanical circulatory support at MTI, as well as director of the Jackson Heart Institute in Miami.
American College of Cardiology
AUGUST 9, 2024
In this episode, Dr. Jonathan Kim is joined by Drs. Michael Ackerman, Rachel Lampert, and Matthew Martinez to discuss the “why†and “how to†related to shared decision-making in the context of sports participation for athletes with heart disease.
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