Med Page Today
AUGUST 5, 2024
(MedPage Today) -- PHILADELPHIA -- Coffee and tea intake were associated with long-term cognitive changes in older adults, two prospective studies presented at the Alzheimer's Association International Conference (AAIC) suggested. Among 6,001.
Nature Reviews - Cardiology
AUGUST 6, 2024
Nature Reviews Cardiology, Published online: 07 August 2024; doi:10.1038/s41569-024-01064-4 In this Review, Ghofrani and colleagues discuss the mechanisms underlying the development of pulmonary arterial hypertension, provide an overview of approved therapies and describe the predominantly non-vasodilatory drugs that are currently being tested in clinical trials.
Science Daily - Heart Disease
AUGUST 7, 2024
Lab-grown organs are a long-time 'holy grail' of organ engineering that has yet to be achieved, but new research has brought that goal a big step closer to reality using a new 3D-printing method called co-SWIFT. co-SWIFT prints branching networks of double-layered vessels that are infused with smooth muscle cells and endothelial cells into living human cardiac tissue, and can even replicate patient-specific vascular structures,indicating that it could one day be used for personalized medicine.
HCPLive
AUGUST 5, 2024
Ocugen will initiate expanded access to OCU400 gene therapy in adults with retinitis pigmentosa prior to BLA approval.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Med Page Today
AUGUST 4, 2024
(MedPage Today) -- PHILADELPHIA -- Intermittent calorie restriction improved executive function and memory measures in cognitively intact older adults, an exploratory pilot study suggested. The 8-week randomized clinical trial of 40 overweight.
Ken Grauer, MD
AUGUST 8, 2024
I was sent the ECG shown in Figure-1 — told only that that this middle-aged woman noted chest tightness and nausea an hour earlier. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? — IF told that this patient arrested shortly after ECG #1 — Does this change your interpretation? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original EC G using PMcardio ).
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
AUGUST 9, 2024
The FDA approved epinephrine nasal spray (Neffy) for the emergency treatment of allergic reactions, including anaphylaxis, in adult and pediatric patients who weigh at least 30 kg.
Cardiology Update
AUGUST 4, 2024
Despite proven benefits in reducing morbidity and mortality, many heart failure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). The 2021 European Society of Cardiology guidelines recommend guideline-directed medical therapy (GDMT) for patients with HF with reduced ejection fraction (HFrEF). This includes beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, and SGLT2 inhibitors.
Heart Sisters
AUGUST 4, 2024
"People often believe that their 'silent' heart attack is something else - like the flu or a pulled muscle. Much later, when they end up getting diagnosed with a heart attack that they didn't know they were having, they might recall an episode of feeling vaguely unwell." - Dr.
Science Daily - Heart Disease
AUGUST 8, 2024
Significant improvements in aerobic fitness were noted after 12 weeks of high-intensity interval training sessions compared to traditional, moderate exercise sessions, according to a new study.
HCPLive
AUGUST 5, 2024
In a "secret shopper" study, investigators posing as Medicaid enrollees found many clinicians in Medicaid provider directories do not accept Medicaid insurance.
Dr. Smith's ECG Blog
AUGUST 4, 2024
Written by Pendell Meyers Try first to interpret the ECG without any clinical context: What do you think? Sinus rhythm with abnormal STE in V2-V6, and I, II, aVF. Reciprocal STD in aVR and V1. Most leads with STE have remarkably non-hyperacute, flat T waves. Most would say that there is Spodick's sign. The PR depression in II (and its reciprocal PR elevation in aVR) is probably beyond normal baseline values.
Dr. Paddy Barrett
AUGUST 9, 2024
More than heart disease or cancer, the risk of dementia often creates much greater anxiety in the patients I see. And given that dementia is routinely in the top 5 leading causes of death, this concern is dually warranted. But can dementia be prevented? The answer is yes. But as I have said many, many times in the past, we need to understand that prevention is usually a shorthand way of saying: “Decrease the odds of something early in life” The reason for this is that when it comes t
Med Page Today
AUGUST 5, 2024
(MedPage Today) -- The biggest risks for organ damage for patients with systemic lupus erythematosus (SLE) come in the first year after diagnosis, analysis of a long-running registry indicated. Among 1,274 members of a large Spanish SLE cohort.
HCPLive
AUGUST 7, 2024
Obesity was more prevalent among patients with gout and obesity indicators were significantly higher in this group.
Dr. Smith's ECG Blog
AUGUST 9, 2024
Written by Colin Jenkins and Nhu-Nguyen Le with edits by Willy Frick and by Smith A 46-year-old male presented to the emergency department with 2 days of heavy substernal chest pain and nausea. He reported a history of “Wolf-Parkinson-White” and “heart attack” but said neither had been treated. These diagnoses were not found in his medical records nor even a baseline ECG.
Science Daily - Heart Disease
AUGUST 7, 2024
A cardiovascular health construct based on the American Heart Association's Life's Essential 8 but enhanced with a ninth psychological health metric strongly predicts all-cause and cardiovascular mortality.
Med Page Today
AUGUST 5, 2024
(MedPage Today) -- A qualitative study of semaglutide (Ozempic, Wegovy) purchases over the internet without a prescription uncovered scams, low purity levels, and possible contamination of products. Quality testing of semaglutide products purchased.
HCPLive
AUGUST 6, 2024
The most commonly reported symptoms were bodily pain, joint tenderness and swelling, and joint pain.
Dr. Smith's ECG Blog
AUGUST 6, 2024
Written by Magnus Nossen with Edits by Grauer and Smith The ECGs in today’s case are from 3 different patients all presenting with new-onset CP ( Chest Pain ). All ECGs were recorded by EMS, and transferred to a PCI capable center for evaluation. For 2 of the 3 patients — the cath lab was activated based on the ECG. One of the patients was lucky to have expert ECG interpretation by the Queen Of Hearts AI model.
Cardiovascular Diabetology
AUGUST 6, 2024
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronary artery disease (CAD). Research design and methods All patients with diabetes and CAD undergoing a coronary angiography between 2010 and 2021 according to the Swedish Angiography and Angioplasty Registry were included. Information on GLD (dispended 6 months before or after coronary angiography) was collected from the Swedish Prescribed Drug Registry.
Med Page Today
AUGUST 6, 2024
(MedPage Today) -- Poor physical function appeared to be the primary reason for increased fracture risk in older women with type 2 diabetes, a prospective observational study suggested. According to Mattias Lorentzon, MD, PhD, of Sahlgrenska University.
HCPLive
AUGUST 6, 2024
A recent study found a high prevalence of head injuries among law enforcement officers may make them more prone to experiencing mental health issues.
Learning + Leading
AUGUST 6, 2024
Often when people visit their local pharmacy, they assume that all the person behind the counter does is dispense medications. While that’s certainly a vital part of the job, the pharmacy technician’s responsibilities extend far beyond filling prescriptions, especially in recent years.
Frontiers in Cardiovascular Medicine
AUGUST 7, 2024
Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades. However, with the compelling evidence on the safety and efficacy of transcatheter aortic valve replacement (TAVR), it has become the gold standard treatment option for many patients with symptomatic severe AS.
Med Page Today
AUGUST 5, 2024
(MedPage Today) -- Note that some links may require registration or subscription. Rock band Aerosmith announced its retirement, saying that a full recovery of singer Steven Tyler's vocal injury does not appear possible. (People) Belgium withdrew.
HCPLive
AUGUST 5, 2024
On August 05, 2024, less than a month prior to its presentation at ESC 24, Bayter has announced topline data from the FINEARTS-HF trial indicating finerenone met the primary endpoint.
JAMA Cardiology
AUGUST 6, 2024
This secondary analysis of the Valsartan in Acute Myocardial Infarction (VALIANT) and Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI (PARADISE-MI) randomized clinical trials investigates the changes over time in sudden death rate after myocardial infarction and the characteristics of people dying suddenly.
Circulation
AUGUST 4, 2024
Circulation, Volume 150, Issue 6 , Page 488-503, August 6, 2024. The pro- and antiarrhythmic effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been extensively studied in preclinical and human trials. Despite early evidence of an antiarrhythmic role of n-3 PUFA in the prevention of sudden cardiac death and postoperative and persistent atrial fibrillation (AF), subsequent well-designed randomized trials have largely not shown an antiarrhythmic benefit.
Hypertension Journal
AUGUST 5, 2024
Hypertension, Ahead of Print. Hypertension is a leading risk factor for cardiovascular morbidity and mortality. Despite the widespread availability of both pharmacological and lifestyle therapeutic options, blood pressure control rates across the globe are worsening. In fact, only 23% of individuals with high blood pressure in the United States achieve treatment goals.
HCPLive
AUGUST 5, 2024
Prolonged gout, repeated flares, and severe pain impact the psychological status of patients.
JAMA Cardiology
AUGUST 6, 2024
This randomized clinical trial investigates the optimal antithrombic therapy after percutaneous left atrial appendage occlusion (LAAO).
American College of Cardiology
AUGUST 7, 2024
The following are key points to remember from an international position statement on multimodality imaging for pericardial disease.
NEJM Journal Watch - Cardiology
AUGUST 9, 2024
Based on recent Medicare data, women interventionalists became inactive at a higher rate than men.
HCPLive
AUGUST 7, 2024
These data point to differences between genders such as time to initiation of treatment, treatment choice, response to medication, adverse events, and adherence.
Physiologically Speaking
AUGUST 9, 2024
Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
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