Med Page Today
FEBRUARY 12, 2024
(MedPage Today) -- Blood protein profiles predicted future dementia in healthy adults, a large longitudinal study showed. Blood samples from over 50,000 people in the U.K. Biobank showed that four proteins -- glial fibrillary acidic protein.
American Heart News - Heart News
FEBRUARY 12, 2024
Embargoed until 4 a.m. CT/5 a.m. ET Monday, Feb. 12, 2024 DALLAS, Feb. 12, 2024 — Dramatic advances in the understanding and treatment of cardiovascular diseases have saved millions of lives in the 100 years since the founding in 1924 of the American.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
C1q/TNF-related protein 4 (CTRP4) is generally thought to be released extracellularly and plays a critical role in energy metabolism and protecting against sepsis. However, its physiological functions in autoimmune diseases have not been thoroughly explored. In this study, we demonstrate that Th17 cell–associated experimental autoimmune encephalomyelitis was greatly exacerbated in Ctrp4–/– mice compared with WT mice due to increased Th17 cell infiltration.
Dr. Smith's ECG Blog
FEBRUARY 16, 2024
Written by Pendell Meyers A teenager was playing basketball when he suddenly developed palpitations and lightheadedness. He presented soon afterward at the Emergency Department with ongoing symptoms. Mentation and blood pressure were normal. He had no chest pain or shortness of breath. Heart rates on the monitor fluctuated from 180-250 bpm. Here is his triage ECG: What do you think?
Ken Grauer, MD
FEBRUARY 15, 2024
The ECG in Figure-1 was obtained from a previously healthy middle-aged man — who presented to the ED ( E mergency D epartment ) for shortness of breath. QUESTIONS: How would YOU interpret the ECG shown in Figure-1 ? Given the irregular irregularity of beats #4-through 17 — Is this a run of AFib ( A trial Fib rillation ) with aberrant conduction? Figure-1: The initial ECG in today's case.
HCPLive
FEBRUARY 15, 2024
This research also included results from a sub-analysis of non-responders with hand eczema to dupilumab and upadacitinib.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Skull development coincides with the onset of cerebrospinal fluid (CSF) circulation, brain-CSF perfusion, and meningeal lymphangiogenesis, processes essential for brain waste clearance. How these processes are affected by craniofacial disorders such as craniosynostosis are poorly understood. We report that raised intracranial pressure and diminished CSF flow in craniosynostosis mouse models associate with pathological changes to meningeal lymphatic vessels that affect their sprouting, expansion,
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Med Page Today
FEBRUARY 16, 2024
(MedPage Today) -- NATIONAL HARBOR, Md. -- Moms who had hypertensive disorders of pregnancy (HDP) or gestational diabetes mellitus (GDM) were more likely to have kids with worse cardiovascular health (CVH) in adolescence, a secondary analysis.
HCPLive
FEBRUARY 15, 2024
Viral Shah, MD, of Indiana University, joins Diabetes Dialogue to discuss a recent proof-of-concept study examining use of tirzepatide in type 1 diabetes.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Blood vessels are continually exposed to circulating lipids, and elevation of ApoB-containing lipoproteins causes atherosclerosis. Lipoprotein metabolism is highly regulated by lipolysis, largely at the level of the capillary endothelium lining metabolically active tissues. How large blood vessels, the site of atherosclerotic vascular disease, regulate the flux of fatty acids (FAs) into triglyceride-rich (TG-rich) lipid droplets (LDs) is not known.
Cardiology Update
FEBRUARY 11, 2024
The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. The study, spanning a decade, enrolled 280 patients, randomly assigned to either TAVI with the CoreValve bioprosthesis or SAVR.
Med Page Today
FEBRUARY 12, 2024
(MedPage Today) -- While rapid weight-loss with bariatric surgery or drugs might temporarily worsen diabetic retinopathy as blood sugar levels are rapidly corrected, the low overall risk likely doesn't outweigh the benefits of weight loss, according.
Cardiovascular Diabetology
FEBRUARY 12, 2024
Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Choline deficiency causes disorders including hepatic abnormalities and is associated with an increased risk of multiple types of cancer. Here, by choline-free diet–associated RNA-Seq analyses, we found that the tumor suppressor p53 drives the Kennedy pathway via PCYT1B to control the growth of lipid droplets (LDs) and their fueling role in tumorigenesis.
American Heart News - Heart News
FEBRUARY 12, 2024
Statement Highlights: The new scientific statement highlights heart disease as the leading cause of death for women and emerging evidence that has identified several gender-specific risk factors for heart disease in women, including complications.
Med Page Today
FEBRUARY 16, 2024
(MedPage Today) -- In people with mild to moderate hypertension taken off antihypertensive treatment, quarterly and biannual injections of novel RNA silencer zilebesiran showed promise for safely reducing systolic blood pressure (BP), the phase.
HCPLive
FEBRUARY 13, 2024
These data may allow for future research into the ways in which adolescent patients may better control their allergic condition.
Science Daily - Heart Disease
FEBRUARY 12, 2024
You can mend a broken heart this valentine s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.
Becker's Hospital Review - Cardiology
FEBRUARY 15, 2024
Fortune and PINC AI named the top cardiovascular hospitals, including teaching hospitals with and without cardiovascular residency programs, and community hospitals.
Med Page Today
FEBRUARY 15, 2024
(MedPage Today) -- History of migraine combined with persistent hot flashes was associated with higher risks for cardiovascular disease and stroke, according to an analysis of women in the Coronary Artery Risk Development in Young Adults (CARDIA.
Medical Xpress - Cardiology
FEBRUARY 16, 2024
Having a heart attack significantly increases the risk of developing other serious long-term health conditions, a major new study shows.
Science Daily - Heart Disease
FEBRUARY 14, 2024
Women who have both migraines and a long-term history of hot flashes and/or night sweats have a slightly higher risk of heart disease and stroke, and young women who have migraines have a higher risk of later persistent menopause symptoms, according to two new papers based on a data from a long-term study of the same group of women from their young adult to middle-age years.
Becker's Hospital Review - Cardiology
FEBRUARY 13, 2024
For Shelley Miyamoto, MD, there were two reasons to become a cardiologist: The mentors she encountered during residency who inspired her and the physiology of the heart.
Med Page Today
FEBRUARY 13, 2024
(MedPage Today) -- Continued treatment with the osteoporosis drug denosumab (Prolia) was tied to a lower risk of developing diabetes in a Taiwanese cohort study. In a propensity score-matched analysis, adherence to denosumab for osteoporosis was.
ECG Cases
FEBRUARY 13, 2024
In this month's ECG Cases blog Dr. Jesse McLaren reviews interpretation of the pre-arrest ECG: identifying high risk ECGs requiring empiric treatment like calcium for hyperkalemia, magnesium for long QT, or reperfusion for Occlusion MI; the intra-arrest ECG: identifying pseudo-PEA; and post-arrest ECG: the importance of serial ECGs to reduce false positive STEMI, role of POCUS to help with the differential of diffuse ST depression with reciprocal ST elevation in aVR, and identifying signs of Occ
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Altered tryptophan catabolism has been identified in inflammatory diseases like rheumatoid arthritis (RA) and spondyloarthritis (SpA), but the causal mechanisms linking tryptophan metabolites to disease are unknown. Using the collagen-induced arthritis (CIA) model, we identified alterations in tryptophan metabolism, and specifically indole, that correlated with disease.
DAIC
FEBRUARY 14, 2024
milla1cf Wed, 02/14/2024 - 18:21 February 14, 2024 — Efemoral Medical , developer of advanced interventional bioresorbable therapies, today announced that the United States Food & Drug Administration ( FDA ) has granted its novel Efemoral Vascular Scaffold System (EVSS) Breakthrough Device status for the treatment of de novo or restenotic lesions of the infrapopliteal arteries in patients with Chronic Limb Threatening Ischemia (CLTI).
HCPLive
FEBRUARY 14, 2024
The approval provides patients with the first-ever treatment option for severe frostbite to prevent the amputation of fingers or toes.
CardiacWire
FEBRUARY 11, 2024
The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. The GATEWAY trial assigned 100 participants (76% women, 43.8 avg. age, 36.9 BMI) to receive Roux-en-Y gastric bypass and medical therapy or only receive medical therapy, finding that after five years… Far more gastric bypass patients cut their BP medication use by at least 30% (80
Cardiovascular Diabetology
FEBRUARY 11, 2024
Heart failure (HF) is increasing at an alarming rate, primary due to the rising in aging, obesity and diabetes. Notably, individuals with type 1 diabetes (T1D) face a significantly elevated risk of HF, leading.
DAIC
FEBRUARY 13, 2024
milla1cf Tue, 02/13/2024 - 17:52 February 13, 2024 — RapidAI , the global leader in developing Artificial Intelligence ( AI ) and clinical workflow solutions to combat life-threatening neurovascular, cardiac, and vascular diseases, today announced the publication of the TIMELESS trial in the New England Journal of Medicine (NEJM). Other select data from research studies unveiled last week at the American Heart Association ’s International Stroke Conference (ISC) underscore and reinforce the pi
HCPLive
FEBRUARY 16, 2024
A groundbreaking phase 1 study using CAR-T cells to treat severe lupus highlights a collaborative effort between the Cellular Therapy Program and rheumatology programs to pioneer innovative patient care.
Dr. Smith's ECG Blog
FEBRUARY 14, 2024
A 41-year-old male who presents to the emergency department with chest pain. Patient reports approximately 2 hours prior to arrival he developed a sharp chest pain that radiates into his left arm and left lower leg. Describes the radiating pain as numbness/tingling. No shortness of breath. No recent travel. No cough. No cardiac history. Here is his ECG: He had a previous ECG on file, from many years prior: What do you think?
Science Daily - Heart Disease
FEBRUARY 16, 2024
The efficiency of oxygen supply to tissues is a factor in the severity of important diseases such as Covid-19 and heart conditions. Scientists already know that the relationship between the length of a person's index and ring fingers, known as the 2D:4D ratio is correlated with performance in distance running, age at heart attack and severity of Covid-19.
DAIC
FEBRUARY 13, 2024
Pictured Left to Right: Members and students of the McGill Gene Editing Laboratory at The Texas Heart Institute in Houston, Texas: Fansen Meng, PhD, Xiao Li, PhD, James Martin, MD, PhD, Rich Li, PhD (back), Maggie Lim (undergraduate student at Rice University front), Yuka Morikawa, PhD, Ann Bromley. © THE TEXAS HEART INSTITUTE 2024 milla1cf Tue, 02/13/2024 - 17:56 February 13, 2024 — Pediatric heart transplantation has long been hailed as a life-saving intervention for children suffering from en
HCPLive
FEBRUARY 13, 2024
Patients with rheumatoid arthritis who received acupuncture had a lower cumulative incidence of ischemic stroke compared to those who did not.
Medical Xpress - Cardiology
FEBRUARY 16, 2024
You may be familiar with high-density, or good cholesterol; low-density lipoproteins (LDL), or bad cholesterol; and their connections to heart health. But what about triglycerides? Often that word gets skimmed over when talking about cholesterol levels.
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