Ken Grauer, MD
MAY 16, 2024
The ECG in Figure-1 — was obtained from an older man who had just completed dialysis — and , is now complaining of abdominal discomfort that radiates to his chest. The consultant interpreted this tracing as “LBBB” ( L eft B undle B ranch B lock ) — but not indicative of anything acute. QUESTIONS: Do you agree with the consultant’s interpretation? How would YOU approach this case?
EMS 12-Lead
MAY 15, 2024
TCP in the ROSC Patient: False Electrical Capture at 75mA Josh Kimbrell, NRP @joshkimbre Judah Kreinbrook, EMT-P @JMedic2JDoc This is the second installment of a blog series showing how transcutaneous pacing (TCP) can be difficult and how you can improve your skills. We will be using redacted information from different cases where paramedics attempted TCP in the field.
HCPLive
MAY 15, 2024
Deepak Bhatt, MD, MPH, MBA, reviews the efficacy and safety data of inclisiran, highlighting its long-term effects and noting that injection site reactions are among the most prominent adverse reactions associated with this medication.
American Heart News - Heart News
MAY 16, 2024
DALLAS, May 16, 2024 — Pregnancy-related deaths in the U.S. have risen 140% over the past three decades and cardiovascular disease is the leading cause.[1] Despite existing medical guidance on pregnancy and cardiovascular health, current trends in health.
DAIC
MAY 14, 2024
Getty Images milla1cf Tue, 05/14/2024 - 13:00 May 14, 2024 — One of the most common genetic heart diseases worldwide, hypertrophic cardiomyopathy (HCM) causes the walls of the left ventricle to become thick and stiff. In about 70 percent of cases, patients with HCM experience obstruction to blood flow, which increases pressures in the heart and can lead to chest pain, shortness of breath and reduced exercise capacity.
Journal of Clinical Investigation - Cardiology
MAY 15, 2024
Lymphedema is a debilitating disease with no effective cure and affects an estimated 250 million individuals worldwide. Prior studies have identified mutations in piezo-type mechanosensitive ion channel component 1 (PIEZO1), angiopoietin 2 (ANGPT2), and tyrosine kinase with Ig-like and EGF-like domains 1 (TIE1) in patients with primary lymphedema. Here, we identified crosstalk between these molecules and showed that activation of the mechanosensory channel PIEZO1 in lymphatic endothelial cells (
Ken Grauer, MD
MAY 11, 2024
The 12-lead ECG and long lead II rhythms shown in Figure-1 — was obtained from an older man with a recent history of “easy fatiguability” and a presyncopal episode. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? Is the group beating due to the Mobitz I or Mobitz II type of 2nd-degree AV block? Figure-1: The initial ECG in today’s case. MY Initial Thoughts on Today’s CASE: For clarity, given the above clinical history — I present my initial thoughts regarding clinical interpretation of
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
American Heart News - Heart News
MAY 14, 2024
Guideline Highlights: The new joint guideline from the American Heart Association and the American College of Cardiology provides recommendations to guide clinicians in the treatment of patients with lower extremity peripheral artery disease (PAD) and.
Journal of Clinical Investigation - Cardiology
MAY 15, 2024
The mammalian SUMO-targeted E3 ubiquitin ligase Rnf4 has been reported to act as a regulator of DNA repair, but the importance of RNF4 as a tumor suppressor has not been tested. Using a conditional-knockout mouse model, we deleted Rnf4 in the B cell lineage to test the importance of RNF4 for growth of somatic cells. Although Rnf4–conditional-knockout B cells exhibited substantial genomic instability, Rnf4 deletion caused no increase in tumor susceptibility.
Science Daily - Heart Disease
MAY 15, 2024
Vegetarian and vegan diets are generally associated with better status on various medical factors linked to cardiovascular health and cancer risk, as well as lower risk of cardiovascular diseases, cancer, and death, according to a new review of 49 previously published papers.
Med Page Today
MAY 16, 2024
(MedPage Today) -- A Massachusetts teen who participated in a spicy tortilla chip challenge on social media died from eating a large quantity of chili pepper extract and also had a congenital heart defect, according to an autopsy report obtained.
DAIC
MAY 15, 2024
milla1cf Wed, 05/15/2024 - 19:05 May 15, 2024 — CardioFocus, Inc. , a medical device company dedicated to advancing ablation treatment for cardiac arrythmias, announced its participation at the Heart Rhythm 2024 conference, taking place in person at the Boston Convention & Exhibition Center and virtually, May 16-19, 2024. CardioFocus will feature its portfolio of innovative ablation systems which optimize lesion creation via confirmed tissue contact and sophisticated energy delivery.
Journal of Clinical Investigation - Cardiology
MAY 15, 2024
Lactylation has been recently identified as a new type of posttranslational modification occurring widely on lysine residues of both histone and nonhistone proteins. The acetyltransferase p300 is thought to mediate protein lactylation, yet the cellular concentration of the proposed lactyl-donor, lactyl-coenzyme A, is about 1,000 times lower than that of acetyl-CoA, raising the question of whether p300 is a genuine lactyltransferase.
Dr. Smith's ECG Blog
MAY 13, 2024
Chest Pain – Benign Early Repol or OMI? Written by Destiny Folk, MD, Adam Engberg, MD, and Vitaliy Belyshev MD A man in his early 60s with a past medical history of hypertension, type 2 diabetes, obesity, and hyperlipidemia presented to the emergency department for evaluation of chest pain. He reported substernal chest pressure with radiation to his left arm that started at work several hours prior to arrival and had somewhat improved since onset.
Med Page Today
MAY 16, 2024
(MedPage Today) -- LONG BEACH, Calif. -- Chlorthalidone was no better than hydrochlorothiazide for reducing the incidence of major renal outcomes in patients with hypertension, a secondary analysis of the randomized Diuretic Comparison Project.
DAIC
MAY 16, 2024
milla1cf Thu, 05/16/2024 - 15:35 May 16, 2024 — A recent publication in the American Heart Association Circulation highlights a comprehensive investigation to assess the impact of revascularization strategies on the health-related quality of life (HRQoL) of patients suffering from chronic limb-threatening ischemia. This study stands as a pivotal exploration into the comparative effectiveness of surgical bypass (Bypass) versus endovascular intervention (Endo) across multiple patient cohorts.
Science Daily - Heart Disease
MAY 13, 2024
People with the heart condition obstructive cardiomyopathy were able to use significantly more oxygen while exercising after taking the investigational drug aficamten, according to a new study.
Journal of Clinical Investigation - Cardiology
MAY 15, 2024
Elevated bone resorption and diminished bone formation have been recognized as the primary features of glucocorticoid-associated skeletal disorders. However, the direct effects of excess glucocorticoids on bone turnover remain unclear. Here, we explored the outcomes of exogenous glucocorticoid treatment on bone loss and delayed fracture healing in mice and found that reduced bone turnover was a dominant feature, resulting in a net loss of bone mass.
Med Page Today
MAY 17, 2024
(MedPage Today) -- Metformin started for pre-diabetes also appeared to reduce patients' risk of developing gout, researchers found. Among 1,154 people with elevated hemoglobin A1c (HbA1c) just short of the threshold for type 2 diabetes who began.
DAIC
MAY 15, 2024
In the dynamic realm of healthcare technology, cardiovascular information systems (CVIS) stand at the forefront, facilitating streamlined operations, enhanced patient care and efficient data management within cardiovascular departments. According to a recent market report from Credence Research, the CVIS market is projected to surge from $1,197 M in 2023 to $2,387 by 2023 — a compound annual growth rate of 7.7%.
American Heart News - Heart News
MAY 14, 2024
DALLAS, May 14, 2024 — Living with a chronic medical condition after surviving a heart attack or stroke may come with additional health and personal care needs. Often survivors must rely on a family member or close friend to help. However, there’s a.
Cardiovascular Diabetology
MAY 14, 2024
Diabetic heart disease (DHD) is a serious complication in patients with diabetes. Despite numerous studies on the pathogenic mechanisms and therapeutic targets of DHD, effective means of prevention and treatme.
HCPLive
MAY 13, 2024
In an interview, King provided an overview of the history of psychedelic research for psychiatric conditions, where we are now, and what hurdles investigators must address.
DAIC
MAY 14, 2024
milla1cf Tue, 05/14/2024 - 12:53 May 14, 2024 — GE HealthCare , a leading global medical technology, pharmaceutical diagnostics and digital solutions innovator, and Medis Medical Imaging , a leading cardiac imaging software company, announced their collaboration aimed at helping advance precision care in the diagnosis and treatment of coronary artery disease ( CAD ).
Society of Thoracic Surgeons - Early Career
MAY 13, 2024
In a bid to foster professional development and guidance for aspiring cardiothoracic surgeons, The Society of Thoracic Surgeons has unveiled a unique mentorship program tailored for medical students and residents.
ECG Cases
MAY 13, 2024
Anton is joined by the world's leading EM researcher in subarachnoid hemorrhage diagnosis Dr. Jeff Perry and EM-Stroke team clinician Dr. Katie Lin for a deep dive into why we still miss this life-threatening diagnosis, the key clinical clues, proper use of decision tools, indications for CT, indications for CTA, indications for LP and CSF interpretation for the sometimes elusive diagnosis of subarachnoid hemorrhage.
Becker's Hospital Review - Cardiology
MAY 13, 2024
Discover the new state-of-the-art Cardiovascular Institute at Glenbrook Hospital in Evanston, IL, offering advanced heart care and future expansion plans.
DAIC
MAY 15, 2024
Getty Images milla1cf Wed, 05/15/2024 - 19:10 May 15, 2024 — A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart— transcatheter aortic valve replacement (TAVR)—and surgical aortic valve replacement (SAVR). In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a n
Science Daily - Stroke
MAY 15, 2024
A recent study has found that an ion transporter protein that regulates the pH of specific brain cells can repair the blood-brain barrier and restore normal brain function after ischemic stroke. The study has revealed novel and specific therapeutic targets for ischemic stroke and related brain conditions for which no targeted treatments exist currently.
Med Page Today
MAY 11, 2024
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.
Science Daily - Heart Disease
MAY 16, 2024
In the United States, about 30-40% of donor hearts aren't considered for transplant due to inadequate function in the donor. This leads to a drop in the number of donated hearts that are available to be matched with someone who needs a heart transplant.
DAIC
MAY 16, 2024
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD). Image courtesy: Getty Images christine.book Thu, 05/16/2024 - 11:23 May 16, 2024 — Timely diagnosis and proper management of peripheral artery disease (P
Science Daily - Stroke
MAY 16, 2024
Singing rehabilitates speech production in post-stroke aphasia. Researchers investigated the rehabilitative effect of singing on the brain.
Med Page Today
MAY 12, 2024
(MedPage Today) -- NEW ORLEANS -- Patients with type 2 diabetes (T2D) hospitalized for ketoacidosis had a higher mortality rate versus patients with type 1 diabetes (T1D), according to a study of national data. In the retrospective study, the.
Science Daily - Heart Disease
MAY 15, 2024
An important new study has advanced how heart failure is detected in women -- meaning more female patients can be diagnosed and at an earlier stage.
DAIC
MAY 16, 2024
Getty Images milla1cf Thu, 05/16/2024 - 15:37 May 16, 2024 — People were more likely to develop a type of treatment-resistant hypertension when they experienced adverse effects of economic and social conditions that influence individual and group differences in health status, known as social determinants of health. Additionally, this risk was higher among Black American adults than white American adults, according to a study funded by the National Institute of Neurological Disorders and Stroke
HCPLive
MAY 17, 2024
Check out this quiz on the NKF's KDOQI recommendations on nutrition in chronic kidney disease, with a focus on their guidance for protein and energy intake!
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