Sat.Feb 17, 2024 - Fri.Feb 23, 2024

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ECG Blog #418 — A Single Lead Tells the Tale.

Ken Grauer, MD

The ECG in Figure-1 was obtained from a previously healthy man in his 40s — who presented to the ED ( E mergency D epartment ) with new-onset CP ( C hest P ain ) that awakened him from sleep. ECG #1 was recorded ~90 minutes after the patient was awakened from sleep. He was still having CP. QUESTIONS: In view of this history — How would YOU interpret the ECG in Figure-1 ?

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Ismail El-Hamamsy, MD, PhD, Named President of the Heart Valve Society

DAIC

Ismail El-Hamamsy, MD, performs a Ross Procedure at The Mount Sinai Hospital in New York City with Paul Stelzer, MD, and Elbert Williams, MD. Photo courtesy of Mount Sinai Health System milla1cf Thu, 02/22/2024 - 13:47 February 22, 2024 — Ismail El-Hamamsy , MD, PhD, Director of Aortic Surgery for the Mount Sinai Health System and the Mount Sinai Randall B.

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How will you save this critically ill patient? A fundamental and lifesaving ECG interpretation that everyone must recognize instantly.

Dr. Smith's ECG Blog

Written by Pendell Meyers A woman in her 30s called EMS for acute symptoms including near-syncope, nausea, diaphoresis, and abdominal pain. EMS arrived and found her to appear altered, critically ill, and hypotensive. An ECG was performed: What do you think? Extremely wide complex monomorphic rhythm just over 100 bpm. The QRS is so wide and sinusoidal that the only real possibilities left are hyperkalemia or Na channel blockade.

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Do Organ Transplants Cause Personality Changes?

Med Page Today

(MedPage Today) -- I have received some unusual phone calls in my nearly 40-year career as a psychiatrist, but Mary's* call was unique. "Dr. Liester," she began, "I don't need to see you as a patient. I just want you to tell me if I'm crazy. You.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Crisis Response Planning Can Reduce Suicide Risk for PTSD Among Veterans

HCPLive

A new study found crisis response planning for PTSD among military veterans had lower onset of suicidal ideation than veterans with self-guided safety planning.

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Researchers explore whether gut microbes cause some COVID-19 patients to have higher blood clot risk

Medical Xpress - Cardiology

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis—the formation of blood clots—researchers report February 23 in the journal Cell Metabolism. The results also revealed that 2MBC is accumulated in individuals with COVID-19, potentially explaining why these patients are at increased risk of thrombosis.

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Could Niacin Actually Induce Heart Disease?

Med Page Today

(MedPage Today) -- Niacin metabolism was associated with incident major adverse cardiovascular events (MACE) and may be linked to the pathogenesis of heart disease via inflammatory pathways, researchers said. In a metabolomics study of stable.

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Physiological Resilience: A New Pillar of Endurance Exercise Performance (Part I of II)

Physiologically Speaking

Endurance performance is determined by three primary variables which were proposed by Dr. Michael Joyner over 3 decades ago in a paper titled “Modeling optimal marathon performance on the basis of physiological factors.” These factors are the performance VO2, lactate threshold, and running economy. Performance VO2 is the average oxygen consumption an athlete has to sustain during an event, e.g., the marathon.

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Occupational Noise Linked to Rheumatoid Arthritis, Osteoarthritis Prevalence

HCPLive

Results of a multivariate logistic regression analysis showed previous exposure to occupational noise was positively associated with both rheumatoid arthritis and osteoarthritis.

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Common hair loss and prostate drug may also cut heart disease risk in men and mice

Science Daily - Heart Disease

The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

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Alzheimer's Supplements Fail Compared With Generic Drugs

Med Page Today

(MedPage Today) -- Galantamine sold as prescription generic drugs was labeled accurately and free of contamination, but galantamine sold as dietary supplements was not, an analysis showed. Across 10 brands of dietary supplements, the actual quantity.

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Eating too much protein is bad for your arteries, and this amino acid is to blame

Science Daily - Stroke

Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.

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Most Effective Atopic Dermatitis Treatments May Pose Greatest Risk of Adverse Events

HCPLive

These findings, to be presented at AAAAI, may allow for greater awareness among clinicians when prescribing eczema therapies.

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Heart Month 2024: my interview with Lindsay Dixon

Heart Sisters

Don’t miss this Heart Month interview about women’s heart health that I did with pharmacist/science communicator Lindsay Dixon!

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Dietary Thiamine Linked With Cognition

Med Page Today

(MedPage Today) -- Dietary thiamine (vitamin B1) intake was linked with cognition in older adults, a longitudinal analysis in China suggested. Over a median follow-up of 5.9 years, cognitive decline risk was minimal at dietary thiamine intake.

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New study suggests target steps per day for reduced risk of heart failure

Science Daily - Heart Disease

In ambulatory women ages 63-99 years, higher amounts of usual daily light and moderate intensity activities were associated with lower risk of developing heart failure with preserved ejection fraction independent of demographic and clinical factors associated with heart failure risk. Accumulating 3,000 steps per day might be a reasonable target that would be consistent with the amount of daily activity performed by women in this study.

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Dynamic Coronary Roadmap Reduces Contrast Use in Percutaneous Coronary Interventions

Cardiology Update

Minimizing iodinated contrast use stands as a critical safety measure in percutaneous coronary interventions (PCI), especially for patients at heightened risk of contrast-induced acute kidney injury (CI-AKI). Dynamic Coronary Roadmap (DCR) serves as a PCI navigation aid by projecting a motion-compensated virtual coronary roadmap overlay onto fluoroscopy, potentially diminishing the necessity for contrast during PCI.

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Greater Daytime Light Exposure Linked to Better Sleep for Parkinson’s Disease

HCPLive

A new study found patients with Parkinson’s disease have a lower daytime light exposure with a mean light intensity of 201.1 lux than controls with a light intensity of 337.7 lux.

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Primordial Prevention Can Protect Black Women's Cardiovascular Health

Med Page Today

(MedPage Today) -- The U.S. kicked off its 60th annual American Heart Month with the sobering news that Black women who have high blood pressure by age 35 face up to triple the risk of a stroke by the time they reach middle age compared with their.

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Link between high levels of niacin -- a common b vitamin -- and heart disease, study suggests

Science Daily - Heart Disease

Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies.

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Hackensack Meridian Jersey Shore University Medical Center Providing State-of-the-Art Medtronic APOLLO Clinical Trial Treating Heart Valve Disease

DAIC

Pictured is the TMVR procedure milla1cf Tue, 02/20/2024 - 15:19 February 20, 2024 — As New Jersey’s leading provider of high-quality cardiac procedures and diagnostic testing and an academic institution, Hackensack Meridian Jersey Shore University Medical Center provides patients with state-of-the-art clinical trials in the management of heart valve disease and congestive heart failure.

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Depressive Symptoms Linked to Greater Risk of Gout

HCPLive

A new study found people with depression are associated with an increased risk of gout. However, not many people with both depression and gout sought out treatment (0.2%).

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FDA: Don't Use Smartwatches, Smart Rings for Blood Glucose Measurements

Med Page Today

(MedPage Today) -- Patients should not use smartwatches or smart rings alone to measure blood glucose levels, the FDA warned on Wednesday. Noninvasive devices that do not rely on finger-pricks or pierce the skin are not authorized, cleared, or.

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Intravascular imaging shown to significantly improve survival, safety and outcomes in stenting procedures

Medical Xpress - Cardiology

Using intravascular imaging to guide stent implantation during percutaneous coronary intervention (PCI) in heart disease patients significantly improves survival and reduces adverse cardiovascular events compared to angiography-guided PCI alone, the most commonly used method.

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Latest research redefines neurodevelopmental risks, outcomes for congenital heart disease

American Heart News - Heart News

Statement Highlights: A new American Heart Association scientific statement updates more than a decade of research identifying, managing and preventing neurodevelopmental delays and disorders among people with congenital heart disease. The new.

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Breaking the Silence: Understanding and Overcoming Stigma Surrounding Fibromyalgia

HCPLive

Fibromyalgia poses challenges extending beyond physical symptoms due to societal misconceptions and inadequate understanding. Clinicians emphasize the importance of addressing mental health, engaging patients actively, and creating supportive environments to improve the wellbeing of these patients.

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Sublingual Acute Stroke Neuroprotectant Dazzles in Phase III Trial

Med Page Today

(MedPage Today) -- For acute ischemic stroke within 48 hours of onset, the novel sublingual combination of edaravone (Radicava) with dexborneol appeared to dramatically improve functional outcomes in the phase III TASTE-SL trial from China. The.

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Physiology Friday #206: Is Too Much Protein Damaging to Your Arteries?

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Zeit Calendar , Examine.com , and my eBook “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Enterprise Imaging: Everything You Need to Know

NOVARAD

Many healthcare directors in today’s economic landscape are facing complications with staff shortages , IT challenges, and inefficient processes. Enterprise imaging is one of the primary solutions hospitals are finding in their search for methods to improve services for patients and work for healthcare professionals.

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Black Youth, Females with Autism Have Greater Odds of Being Placed in Foster Care

HCPLive

Among youth with intellectual disabilities and autism, black children and females are more likely to be placed in foster care, a new study found.

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Intravascular Imaging-Guided PCI Reaches a Turning Point With Survival, MI Benefits

Med Page Today

(MedPage Today) -- For the first time, intravascular imaging-guided coronary stenting was associated with better survival and reduced myocardial infarction (MI) in a meta-analysis powered to detect these benefits against angiography, researchers.

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High platelet adrenergic activity and concomitant activation of the pituitary/medullar axis as alarming laboratory parameters in ACS survivors—the STRESS-AMI study

Frontiers in Cardiovascular Medicine

Introduction Kinetics of stress-related biological parameters were determined in acute coronary syndrome (ACS) patients undergoing complex cardiovascular rehabilitation. Methods We determined platelet functionality in the absence/presence of a selective alpha-2 adrenergic receptor inhibitor, atipemazole parallel with salivary cortisol levels at enrolment, and at 3- and 12-months follow-up in 75 ACS patients with percutaneous coronary intervention.

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Genes affect your blood pressure from early childhood, data show

Medical Xpress - Cardiology

Certain genes associated with hypertension affect blood pressure from early in life, and they increase the risk of cardiovascular disease as you get older. But you can do something about it.

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REVIVE: ??Rusfertide Effective for Erythrocytosis Control in Polycythemia Vera

HCPLive

Rusfertide maintained a hematocrit of <45% and reduced or eliminated the use of phlebotomy in patients with polycythemia vera.

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Mechanisms of endothelial activation, hypercoagulation and thrombosis in COVID-19: a link with diabetes mellitus

Cardiovascular Diabetology

Early since the onset of the COVID-19 pandemic, the medical and scientific community were aware of extra respiratory actions of SARS-CoV-2 infection. Endothelitis, hypercoagulation, and hypofibrinolysis were i.

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Intravascular lithotripsy (IVL) enabled the percutaneous closure of a severely calcified paravalvular leak regurgitation following implantation of a self-expandable transcatheter aortic valve: a case report

Frontiers in Cardiovascular Medicine

Background Closure of paravalvular leak (PVL) regurgitation after self-expandable (SE) transcatheter aortic valve implantation (TAVI) may be more challenging than after balloon-expandable (BE) valve implantation. Case summary An 85-year-old woman suffering from long-standing atrial fibrillation and severe symptomatic aortic stenosis underwent SE TAVI (26 mm Evolut™ R®, Medtronic Inc., MN, USA).