Sat.Jun 22, 2024 - Fri.Jun 28, 2024

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ECG Blog #435 — Did Cath Show Acute Ischemia?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from a middle-aged woman with positional tachycardia and diaphoresis with change of position from suprine to sitting. Although CP ( C hest P ain ) was not a prominent symptom — ACS ( A cute C oronary S yndrome ) was suspected from the chest lead T wave inversion seen on this ECG. QUESTIONS: How would YOU interpret the ECG in Figure-1 ?

Blog 172
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More Evidence That Flu Is Linked to Heart Attacks

Med Page Today

(MedPage Today) -- Influenza infection was associated with an increased risk of acute myocardial infarction (MI), especially for those without a prior hospitalization for coronary artery disease (CAD), according to a Dutch observational case series.

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Global epidemiology of heart failure

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 26 June 2024; doi:10.1038/s41569-024-01046-6 In this Review, Khan and colleagues explore the evolving global epidemiology of heart failure (HF), focusing on changes in incidence and prevalence across the spectrum of left ventricular ejection fraction. The authors highlight the disparities in our understanding of HF epidemiology in low-income and middle-income countries, affirming the need for improved surveillance and resource allocation in vulnerable

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Generic Liraglutide (Victoza) Becomes First Generic GLP-1 Receptor Agonist

HCPLive

Teva Pharmaceuticals’ launch of an authorized generic of liraglutide injection 1.8 mg (Victoza) for type 2 diabetes makes it the first-ever generic GLP-1.

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ECG Blog #436 — Bigeminy or Alternans?

Ken Grauer, MD

The ECG in Figure-1 — was obtained from an older man with known coronary disease. He was on a number of medications — including antiplatelet agents, a statin drug and Digoxin. The patient presented to the ED ( E mergency D epartment ) for an episode of syncope. He developed cardiac arrest shortly after the ECG in Figure-1 was recorded. QUESTIONS: How would YOU interpret the ECG in Figure-1 ?

Blog 160
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Challenges and opportunities in the management of type 2 diabetes in patients with lower extremity peripheral artery disease: a tailored diagnosis and treatment review

Cardiovascular Diabetology

Lower extremity peripheral artery disease (PAD) often results from atherosclerosis, and is highly prevalent in patients with type 2 diabetes mellitus (T2DM). Individuals with T2DM exhibit a more severe manifes.

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Cardiovascular Risks Established in Childhood Don't Just Go Away

Med Page Today

(MedPage Today) -- People showed lingering long-term effects of childhood cardiovascular risk factors no matter the changes in adulthood, a population-level cohort study found. Various childhood risk factors were associated with adult cardiovascular.

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A woman in her 50s with multiple episodes of syncope

Dr. Smith's ECG Blog

By Sofiya Diurba MD, reviewed by Meyers, Grauer A woman in her 50s with PMH known RBBB and prior syncopal events presents to the ED for five syncopal events over the last 24 hours. Each event is associated with a prodrome of mild substernal CP, SOB, and “brain fog.” EMS reports intermittent sinus tachycardia and bradycardia secondary to some type of heart block during transport.

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Expansion of AstraZeneca’s Flagship Health Equity Program Healthy Heart Africa

DAIC

milla1cf Fri, 06/28/2024 - 19:07 June 28, 2024 — AstraZeneca has set out a new ambition for Healthy Heart Africa , its flagship health equity initiative, to target a broader range of non-communicable diseases (NCDs), including chronic kidney disease (CKD) as well as hypertension and cardiovascular disease. The expanded program will also launch in Egypt, reaching even more patients across the continent.

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A Call to Action on Gestational Diabetes

Med Page Today

(MedPage Today) -- ORLANDO -- Earlier screening and treatment for gestational diabetes, as well as a "shift to a holistic life-course approach," are needed to reduce the toll it takes on women. That was the conclusion of a series of papers published.

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'A hearty debate' concludes plant-based meat alternatives are healthier for your heart than meat

Science Daily - Heart Disease

Even though there is substantial variability in the contents and nutritional profiles of plant-based meat alternatives (PBMAs), the nutritional profiles tend to reflect a heart-healthy dietary pattern. A review article of the available studies directly comparing the impact of plant-based and animal-based meats consistently suggests that the plant-based alternatives improve cardiovascular risk factors.

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We have a judgment (Part 1)

Dr. Malcolm Kendrick

25 June 2024 In the case against the Mail on Sunday (Associated Newspapers) and Barney Calman, Health Editor of the Mail on Sunday. I have written nothing on this blog for a while, because of my on-going legal case. Now we have a judgment, part one. Step backwards for a moment. Zoë Harcombe and I are suing the Mail on Sunday and Barney Calman for libel.

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Endotronix Receives FDA Premarket Approval of the Cordella PA Sensor System for the Treatment of Heart Failure

DAIC

milla1cf Mon, 06/24/2024 - 20:21 June 24, 2024 — Endotronix, Inc. , a privately held company dedicated to advancing the treatment of heart failure ( HF ) at the intersection of digital health and medtech, today announced Premarket Approval (PMA) from the U.S Food and Drug Administration ( FDA ) of the company's Cordella Pulmonary Artery (PA) Sensor System for the treatment of New York Heart Failure (NYHA) class III heart failure patients.

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More Than 1 in 4 Seniors Have Asymptomatic Valve Disease

Med Page Today

(MedPage Today) -- Undiagnosed heart valve disease was highly prevalent in a large community study of otherwise healthy people recruited from primary care in the U.K., researchers found. There was a 28.2% prevalence of mild, moderate, or severe.

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VF arrest at home, no memory of chest pain. Angiography non-diagnostic. Does this patient need an ICD? You need all the ECGs to know for sure.

Dr. Smith's ECG Blog

Written by Willy Frick A man in his 50s was at home with his family when they heard a thud and rushed into the room to find him unconscious with agonal respirations. His daughter immediately started CPR and another family member called EMS. When EMS arrived the patient was in ventricular fibrillation. They shocked him twice before return of spontaneous circulation.

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Apremilast Effective, Safe Among Psoriasis Patients with Special Area Involvement

HCPLive

This analysis among Japanese patients highlights the potential of apremilast for psoriasis patients not responding to topical therapy who may have limited systemic treatment options.

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Gender Gaps in Cardiovascular Disease Diagnosis and Treatment Persist

DAIC

Getty Images milla1cf Fri, 06/28/2024 - 08:10 June 27, 2024 — Cardiovascular disease is the leading cause of death for women, and gaps in care and access persist between women and men. Addressing those gaps could lead to an increase of at least 1.6 million years of quality life and boost the U.S. economy by $28 billion annually by 2040, according to a new report published today by the American Heart Association and the McKinsey Health Institute (MHI).

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Surprisingly High Hypercortisolism Prevalence With Uncontrolled Type 2 Diabetes

Med Page Today

(MedPage Today) -- ORLANDO -- A surprisingly high prevalence of hypercortisolism was found in people with uncontrolled diabetes, according to the two-part, phase IV CATALYST study. Of 1,055 patients with difficult-to-treat type 2 diabetes, 24.

Diabetes 110
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Duke Health launches cardiology AI testing lab

Becker's Hospital Review - Cardiology

The healthcare field is facing a deluge of potential artificial intelligence products, and Durham, N.C.-based Duke Health has opened an AI testing lab to determine which products are the most effective for heart care.

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New 52-Week Data Highlights Benefits of Tildrakizumab for Psoriasis

HCPLive

These real-world findings on tildrakizumab’s use among patients with moderate-to-severe plaque psoriasis highlight the drug’s efficacy regarding high burden symptoms.

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Study Defines the Process of and Defenses Against Cardiac Valve Calcification

DAIC

Partially calcified valve leaflet tissue, including unaltered collagen (blue), calcified collagen (yellow to red) and aggregated calcium phosphate nodules. Image provided by Mayandi Sivaguru and Bruce Fouke, Roy, J. Carver Biotechnology Center, University of Illinois milla1cf Fri, 06/28/2024 - 08:14 June 27, 2024 — The human body has sophisticated defenses against the deposition of calcium minerals that stiffen heart tissues, researchers at the University of Illinois Urbana-Champaign and collabo

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Novel Triple-Hormone Agonist Boosts Beta-Cell Function in T2D

Med Page Today

(MedPage Today) -- ORLANDO -- An investigational triple-hormone receptor agonist improved metabolic profiles of people with obesity with or without type 2 diabetes, an exploratory biomarker analysis of a phase II trial found. After 36 weeks.

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Common blood pressure drug may make leukemia more responsive to chemotherapy while protecting heart

Medical Xpress - Cardiology

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

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Diabetes Dialogue: Blue Circle Health, with Monica Gomberg, MD

HCPLive

Monica Gomberg, MD, joins the podcast to discuss how Blue Circle Health leverages free support and education programs to improve management and quality of life in people with types 1 diabetes.

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Society of Cardiovascular Computed Tomography Annual Scientific Meeting SCCT24 Preview

DAIC

June 27, 2024 — The countdown has begun for the Society of Cardiovascular Computed Tomography (SCCT) 19th Annual Scientific Meeting, SCCT24, “At the heart of it,” to be held July 18-21, in Washington, DC. Planners have designed this year’s program and events to engage physicians, trainees, technologists and healthcare professionals in a complete overview of the cardiovascular CT field.

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A More Selective Enoxaparin Thromboprophylaxis Protocol May Be Safer for New Moms

Med Page Today

(MedPage Today) -- A more selective risk-stratified approach to postpartum enoxaparin (Lovenox) thromboprophylaxis for venous thromboembolism (VTE) was linked to reduced rates of wound hematomas without increasing the rate of VTE, according to.

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“What? So what? Now what?” Self-reflection for the new heart patient

Heart Sisters

Most patients aren't experienced enough to be competent in handling a scary new diagnosis, but here's how self-reflection can make a difference during recovery.

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FDA Approves Ensifentrine (Ohtuvayre) for COPD

HCPLive

Ensifentrine, a PDE3 and 4 inhibitor from Verona Pharma, was associated with significantly improved lung function and reduced COPD exacerbations over 24 weeks.

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JACC to Serve Cardiovascular Community, Shape Future Under New Editor

DAIC

Harlan M. Krumholz, MD, SM, FACC milla1cf Wed, 06/26/2024 - 18:57 June 26, 2024 — The first issue of JACC , the flagship journal of the American College of Cardiology , under new Editor-in-Chief Harlan M. Krumholz , MD, SM, FACC, published this week, ushering in a new era of one of the world’s leading scholarly journals. “I envision JACC, with all its strengths, as a transformative platform for building community, elevating strong science, influencing clinical practice, supporting career devel

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Low-Dose SGLT2 Inhibitor May Protect Kidneys in Youth With T1D

Med Page Today

(MedPage Today) -- ORLANDO -- Adding a low dose of an SGLT2 inhibitor to insulin improved renal function and glycemic control in adolescents with type 1 diabetes (T1D), the late-breaking ATTEMPT trial found. In the 98-patient study, treatment.

Diabetes 104
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Urban green and blue spaces are linked to less coronary artery calcification

Science Daily - Heart Disease

Being near and having more exposure to urban green space and blue (water) space is linked to lower odds of having coronary artery calcification in middle age, which is an early marker of cardiovascular disease. The associations were more pronounced among Black individuals and those living in neighborhoods with lower socioeconomic status, with the strongest effects observed in Black individuals in economically deprived neighborhoods.

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Mechanism of Action of Elamipretide for GA in Dry AMD

HCPLive

Arshad Khanani, MD describes the mechanism of action of elamipretide, an investigational product candidate for geographic atrophy in dry age-related macular degeneration.

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Data Supporting Nanox.AI Cardiac Solution to Be Presented at 19th Annual Meeting of the Society of Cardiovascular Computed Tomography

DAIC

milla1cf Tue, 06/25/2024 - 18:58 June 25, 2024 — Nano-X Imaging (Nanox), an innovative medical imaging technology company, today announced that data from five studies supporting the AI Cardiac Solution (HealthCCSng) of its subsidiary, Nanox AI, will be presented at the 19th Annual Meeting of the Society of Cardiovascular Computed Tomography ( SCCT ), being held July 18-21 in Washington, D.C.

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Nationwide Coffee Recall; Aspirin Misuse Common; Gena Rowlands' Alzheimer's Disease

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Snapchill recalled all of its canned coffee products distributed nationwide through coffee roasters and retailers due to potential botulinum toxin contamination.

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Cardiovascular health could be biggest risk factor for future dementia rates

Medical Xpress - Cardiology

Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers.

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Guselkumab Effective as Treatment for Facial, Genital Psoriasis

HCPLive

These data were identified to expand upon existing information regarding treatment options for facial psoriasis and/or genital psoriasis.

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Heart Hospital of New Mexico at Lovelace Medical Center and GE HealthCare Collaborate to Install the First Allia IGS Pulse Electrophysiology Lab in the United States for Minimally Invasive Cardiovascular Procedures

DAIC

milla1cf Tue, 06/25/2024 - 18:52 June 25, 2024 — Heart Hospital of New Mexico at Lovelace Medical Center (HHNM) and GE HealthCare (announced HHNM as the first location in the United States to install GE HealthCare ’s latest Allia Image Guided System (IGS) Pulse, which was designed to provide exceptional image quality and improve workflow for the diagnosis and treatment of cardiovascular diseases ( CVD ).