Ken Grauer, MD
NOVEMBER 25, 2023
== CLICK HERE — for a V ideo presentation of this case! ( 19:40 min. ) Below are slides used in my video presentation. For full discussion of this case — See ECG Blog #191 — == The 2-lead rhythm strip shown in Figure-1 was obtained from an elderly woman who presented to the ED following a syncopal episode. On the basis of this rhythm strip — she was diagnosed as being in complete AV Block.
Science Daily - Stroke
NOVEMBER 30, 2023
Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.
Dr. Smith's ECG Blog
NOVEMBER 29, 2023
Written by Pendell Meyers Two adult patients in their 50s called EMS for acute chest pain that started within the last hour. Both were awake and alert with normal vital signs. Both cases had an EMS ECG that was transmitted to the ED physician asking "should we activate the cath lab?" What do you think? Here they are: Patient 1, ECG1: Zoll computer algorithm stated: " STEMI , Anterior Infarct" Patient 2, ECG1: Zoll computer algorithm stated: "ST elevation, probably benign early repolarization.
ECG Cases
NOVEMBER 28, 2023
On this month's EM Quick Hits podcast: Anand Swaminathan on update to ED management of postpartum hemorrhage, Nour Khatib on serotonin syndrome and its mimics, Katie Lin on an approach to recognition and management of severe TBI and brain herniation syndromes, Hans Rosenberg on the ED management of ulcerative colitis, Heather Cary on pediatric c-spine immobilization controversies and techniques, Navpreet Sahsi on the difference between humanitarian and development work The post EM Quick Hits 53
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Ken Grauer, MD
DECEMBER 1, 2023
== CLICK HERE — for a V ideo presentation of this case! ( 19:40 min. ) Below are slides used in my video presentation. For full discussion of this case — See ECG Blog #351 — == The ECG in Figure-1 — was obtained from a previously healthy older man who contacted EMS ( E mergency M edical S ervices ) because of "chest tightness" that began ~1 hour earlier.
Cassling
DECEMBER 1, 2023
As Cassling continues to grow, we’re always evolving to better serve our customers. One way we’re doing this is by expanding our equipment service offerings. Expanded service is an ask that came from our customers, and it is a direct result of the trust and confidence they have in dedicated field service engineers like Jeremy Long.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Med Page Today
NOVEMBER 30, 2023
(MedPage Today) -- Giving unstable brain-dead heart donors intravenous levothyroxine did not lead to more hearts being transplanted, a randomized trial showed. In hemodynamically unstable potential donors, administering the thyroid hormone supplement.
Physiologically Speaking
DECEMBER 1, 2023
Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
Conquering CHD
NOVEMBER 29, 2023
We have some fantastic news to share with all of you! After a hiatus, we are thrilled to announce the triumphant return of Conquering CHDs National Committees. These dedicated committees are the heart and soul of our organization, and they play a vital role in our mission to support those affected by congenital heart defects (CHDs). If you’re interested in getting involved with any of these committees, want to learn more, or wish to apply, please see our National Committee page for details
American Heart News - Heart News
NOVEMBER 30, 2023
DALLAS and WASHINGTON (Nov. 30, 2023) — The American Heart Association (AHA) and the American College of Cardiology (ACC), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrial.
Med Page Today
DECEMBER 1, 2023
(MedPage Today) -- Among younger patients undergoing total hip or knee replacement, whether they received aspirin versus direct oral anticoagulants (DOACs) did not seem to affect their risk of venous thromboembolism (VTE) following surgery, a large.
Science Daily - Heart Disease
NOVEMBER 28, 2023
Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists -- so far. A new multi-chamber organoid that mirrors the heart's intricate structure enables scientists to advance screening platforms for drug development, toxicology studies, and understanding heart development.
Journal of the American Heart Association
DECEMBER 1, 2023
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundAn increased risk of recurrent stroke is noted in patients with atrial fibrillation despite direct oral anticoagulant (DOAC) use. We investigated the efficacy and safety of treatment with each of 4 different DOACs or warfarin after DOAC failure.Methods and ResultsWe retrospectively analyzed patients with atrial fibrillation with ischemic stroke despite DOAC treatment between January 2002 and December 201
American Heart News - Heart News
NOVEMBER 29, 2023
Research Highlights: People diagnosed with coronary heart disease had a significantly increased risk of developing dementia later in life, according to an analysis of data for more than 430,000 people from the UK Biobank. Participants who had.
Med Page Today
DECEMBER 1, 2023
(MedPage Today) -- A custom artificial intelligence (AI) app for insulin management advice helped patients with type 2 diabetes gain rapid glycemic control, a small randomized clinical trial found. In titrating basal insulin, those who used a.
Circulation
NOVEMBER 29, 2023
Circulation, Ahead of Print. AimThe “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation” provides recommendations to guide clinicians in the treatment of patients with atrial fibrillation.MethodsA comprehensive literature search was conducted from May 12, 2022, to November 3, 2022, encompassing studies, reviews, and other evidence conducted on human subjects that were published in English from PubMed, EMBASE, the Cochrane Library, the Agency for Healthcare Re
Journal of the American Heart Association
DECEMBER 1, 2023
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundThe relationship between resting heart rate (RHR) and the risk of end‐stage renal disease (ESRD) among those without cardiovascular disease remains unclear. We aim to establish temporal consistency and elucidate the independent relationship between RHR and the risk of ESRD.Methods and ResultsThis cohort enrolled participants from 476 347 individuals who had taken part in a screening program from 1996 to
JAMA Cardiology
NOVEMBER 30, 2023
This secondary analysis of a randomized clinical trial assesses whether myocardial viability testing identifies patients with ischemic left ventricular dysfunction who benefit from percutaneous coronary intervention.
Stroke Journal
NOVEMBER 30, 2023
Stroke, Ahead of Print. BACKGROUND:Stroke survivors with impaired balance and motor function tend to have relatively poor functional outcomes. The cerebellum and primary motor cortex (M1) have been suggested as targets for neuromodulation of balance and motor recovery after stroke. This study aimed to compare the efficacy and safety of intermittent theta-burst stimulation (iTBS) to the cerebellum or M1 on balance and motor recovery in patients with stroke.METHODS:In this randomized, double-blind
Circulation
NOVEMBER 29, 2023
Circulation, Ahead of Print. BACKGROUND:Cholesterol efflux capacity (CEC) predicts cardiovascular disease independently of high-density lipoprotein (HDL) cholesterol levels. Isolated small HDL particles are potent promoters of macrophage CEC by the ABCA1 (ATP-binding cassette transporter A1) pathway, but the underlying mechanisms are unclear.METHODS:We used model system studies of reconstituted HDL and plasma from control and lecithin-cholesterol acyltransferase (LCAT)–deficient subjects to inve
Journal of Cardiovascular Electrophysiology
NOVEMBER 29, 2023
Abstract Left ventricular assist device (LVAD) implantation is an established treatment for patients with advanced heart failure refractory to medical therapy. However, the incidence of ventricular arrhythmias (VAs) is high in this population, both in the acute and delayed phases after implantation. About one-third of patients implanted with an LVAD will experience sustained VAs, predisposing these patients to worse outcomes and complicating patient management.
Science Daily - Heart Disease
NOVEMBER 29, 2023
Having coronary heart disease at a younger age was associated with an increased risk of dementia, Alzheimer's disease and vascular dementia, finds a new study.
Stroke Journal
NOVEMBER 28, 2023
Stroke, Ahead of Print.
European Journal of Heart Failure
NOVEMBER 29, 2023
ABSTRACT Aims Heart failure outcomes remain poor despite advances in therapy. The European Society of Cardiology Heart Failure III Registry (ESC HF III Registry) aims to characterize HF clinical features and outcomes and to assess implementation of guideline-recommended therapy in Europe and other ESC affiliated countries. Methods Between 1 November 2018 and 31 December 2020, 10 162 patients with chronic or acute/worsening HF with reduced, mildly reduced, or preserved ejection fraction were enro
The New England Journal of Medicine
NOVEMBER 29, 2023
Wearable DHT has reached an inflection point between fanciful descriptions and practical applications. The editors announce a series of articles focusing on the clinical applications of wearable DHT.
Journal of the American Heart Association
NOVEMBER 29, 2023
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundThe association of age at coronary heart disease (CHD) onset with incident dementia remains unexplored. This study aimed to examine whether younger onset age of CHD is associated with a higher risk of incident dementia.Methods and ResultsData were obtained from the UK Biobank.
Stroke Journal
NOVEMBER 28, 2023
Stroke, Ahead of Print. BACKGROUND:Dental caries is a highly prevalent disease worldwide. In the United States, untreated dental caries is present in >1 in 5 adults. The objective of this study was to determine the relationship between dental caries and incident ischemic stroke, coronary heart disease (CHD) events, and death.METHODS:The dental cohort (n=6351) of the ARIC study (Atherosclerosis Risk in Communities) was followed for incident ischemic stroke, CHD event, and all-cause mortali
Circulation: Cardiovascular Imaging
NOVEMBER 30, 2023
Circulation: Cardiovascular Imaging, Ahead of Print.
Becker's Hospital Review - Cardiology
NOVEMBER 30, 2023
Sacramento, Calif.-based Sutter Health has taken part in testing and researching a headset designed to help emergency technicians better identify large vessel occlusion ischemic strokes prior to patients arriving at the hospital.
Journal of the American Heart Association
DECEMBER 1, 2023
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023.
JAMA Cardiology
NOVEMBER 30, 2023
This cross-sectional study measures the association of lipoprotein(a) concentrations in pairs of first- and second-degree relatives of participants in the UK Biobank with high lipoprotein(a) levels.
Science Daily - Heart Disease
NOVEMBER 28, 2023
Optimal windows exist for action and perception during the 0.8 seconds of a heartbeat, according to new research. The sequence of contraction and relaxation is linked to changes in the motor system and its ability to respond to stimulation, and this could have implications for treatments for depression and stroke that excite nerve cells.
Hypertension Journal
NOVEMBER 29, 2023
Hypertension, Ahead of Print. Hypertension-associated cerebral small vessel disease is a common finding in older people. Strongly associated with age and hypertension, small vessel disease is found at autopsy in over 50% of people aged ≥65 years, with a spectrum of clinical manifestations. It is the main cause of lacunar stroke and a major source of vascular contributions to cognitive impairment and dementia.
Journal of the American Heart Association
DECEMBER 1, 2023
Journal of the American Heart Association, Volume 12, Issue 23 , December 5, 2023. BackgroundThe incidence and type of complications following catheter ablation of atrial fibrillation have been extensively examined, but the impact associated with these complications on the length of stay and hospitalization costs is unknown.Methods and ResultsThis cohort study included 20 117 adult patients (mean age 62.6±11.4 years, 30.3% women, median length of stay 1 day [interquartile range 1–2 days]) underg
Stroke Journal
NOVEMBER 28, 2023
Stroke, Ahead of Print. Stroke is a leading cause of paralysis, most frequently affecting the upper limbs and vocal folds. Despite recent advances in care, stroke recovery invariably reaches a plateau, after which there are permanent neurological impairments. Implantable brain-computer interface devices offer the potential to bypass permanent neurological lesions.
Science Daily - Heart Disease
NOVEMBER 29, 2023
The ARIES-HM3 Randomized Clinical Trial assessed the safety and efficacy of excluding aspirin from the antithrombotic regimen in patients with advanced heart failure who have undergone implantation of a fully magnetically levitated left ventricular assist device (LVAD). The clinical trial found that excluding aspirin from the antithrombotic regimen in patients with a levitated left ventricular assist device was safe.
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