Sat.Jul 06, 2024 - Fri.Jul 12, 2024

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Mediterranean Diet Good for Kids, Teens Too

Med Page Today

(MedPage Today) -- The Mediterranean diet improved cardiometabolic health among kids and teens, a meta-analysis of randomized clinical trials affirmed. Interventions following the diet's characteristic emphasis on fruit, vegetables, olive oil.

Diet 133
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Artificial Intelligence Speeds Up Heart Scans, Leading to Efficiency and Improving Outcomes

DAIC

Pankaj Garg, MD mtaschetta-millane Fri, 07/12/2024 - 11:14 July 12, 2024 — Researchers have developed a groundbreaking method for analyzing heart MRI scans with the help of artificial intelligence , which could save valuable NHS time and resources, as well as improve care for patients. The teams from the Universities of East Anglia (UEA), Sheffield and Leeds created an intelligent computer model that utilizes AI to examine heart images from MRI scans in a specific view known as the four-chamber

Outcomes 122
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Artificial intelligence speeds up heart scans, saving doctors' time, and could lead to better treatment for heart conditions

Science Daily - Heart Disease

Researchers have developed a groundbreaking method for analysing heart MRI scans with the help of artificial intelligence, which could save valuable time and resources, as well as improve care for patients.

Research 119
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Consequences of ionizing radiation exposure to the cardiovascular system

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 10 July 2024; doi:10.1038/s41569-024-01056-4 In this Review, Wu and co-workers describe the consequences of radiation exposure on the cardiovascular system, drawing insights from individuals exposed to whole-body radiation (including nuclear and medical workers) and from patients with cancer undergoing radiation therapy.

Cancer 116
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Don't Try ARBs for Severe COVID, Trial Indicates

Med Page Today

(MedPage Today) -- The angiotensin receptor blocker (ARB) losartan led to hypotension and failed to improve mortality in patients hospitalized for acute COVID-19, according to the randomized, prospective -- and prematurely terminated -- ARBs.

COVID-19 130
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AI speeds up heart scans, saves time, and could lead to better treatment for heart conditions

Medical Xpress - Cardiology

Researchers have developed a method for analyzing heart MRI scans with the help of artificial intelligence, which could save valuable NHS time and resources, as well as improve care for patients.

Research 107
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Study Calls for Targeted Strategies for Managing Diabetic Cardiomyopathy Across Racial, Ethnic Groups

DAIC

Findings from an observational analysis of ARISE-HF trial participants, newly-published in the Journal of the American College of Cardiology, JACC, shed light on the racial and ethnic disparities in diabetic cardiomyopathy (DbCM), which researchers note may have the potential to inform clinical practice, interventions, and policies. Image courtesy: Getty Images christine.book Wed, 07/10/2024 - 12:02 July 10, 2024 — Findings from an observational analysis of ARISE-HF trial participants, newly-pub

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In Parkinson's Disease, Cognitive Symptoms Often Emerge Soon After Diagnosis

Med Page Today

(MedPage Today) -- About a third of people with Parkinson's disease reported cognitive symptoms early in the disease course, a large cross-sectional study showed. Of 25,000 Fox Insight study participants who had a Parkinson's diagnosis for a median.

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SGLT2 Inhibitor, GLP-1 RA Combination Improves Cardiovascular, Kidney Outcomes in Diabetes

HCPLive

Findings from a meta-analysis examining 12 trials including more than 70,000 patients with diabetes support combining SGLT2 inhibitors and GLP-1 RAs.

Diabetes 119
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Reviva Announces Grant of European Patent Covering Use of Brilaroxazine for the Treatment of Pulmonary Hypertension

DAIC

Getty Images mtaschetta-millane Wed, 07/10/2024 - 08:51 July 10, 2024 — Reviva Pharmaceuticals Holdings, Inc. , a late-stage pharmaceutical company developing therapies that seek to address unmet medical needs in the areas of central nervous system (CNS), inflammatory and cardiometabolic diseases, today announced European Patent EP3244896 has been granted by the European Patent Office (EPO) covering use of brilaroxazine for the treatment of PH, adding to its existing patent protection in key ma

Pulmonary 111
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Physiology Friday #226: Optimizing Post-exercise Recovery: Embrace Heat and Forget about Cold

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Exercise 102
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Mediterranean Diet Tied to Lower Mortality Risk in Cancer Survivors

Med Page Today

(MedPage Today) -- Long-term cancer survivors tended to live longer if they consumed a Mediterranean diet, analysis of an Italian cohort study found. With a follow-up of almost 13 years, survivors with high adherence to the diet had a 32% lower.

Diet 122
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A diagnostically challenging case of wide complex tachycardia

Heart BMJ

Clinical introduction A woman in her 60s with non-obstructive coronary artery disease, aortic valve replacement and aortic arch repair, chronic diastolic heart failure and paroxysmal atrial fibrillation (AF) and flutter (AFL), presented with 3 days of sustained palpitations that felt similar to prior episodes of AF/AFL. She was euvolemic, haemodynamically stable, with a regular rhythm.

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American Heart Association Announces New 2024-2025 National Volunteer Leaders

DAIC

The American Heart Association, commemorating its 100th year, has announced its volunteer leadership for fiscal year 2024-2025, which includes Keith Churchwell, MD, FAHA, a cardiologist renowned as a health equity champion, and Marsha Jones, an executive leader in workplace diversity and inclusion. Image courtesy: American Heart Association christine.book Tue, 07/09/2024 - 10:55 July 9, 2024 — The American Heart Association , celebrating 100 years of lifesaving service as the world’s leading non

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A man in his 50s with unwitnessed VF arrest, defibrillated to ROSC, and no STEMI criteria on post ROSC ECG. Should he get emergent angiogram?

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 50s was found by his family in cardiac arrest of unknown duration. His family started CPR and called EMS, who arrived to find him in ventricular fibrillation. 15 minutes after EMS arrival, after at least 6 defibrillations, the patient achieved sustained ROSC. He arrived to the ED with severe hypotension, heart rate in the 70s, unable to follow commands but moving all extremities requiring restraint and sedation, respiratory rate around 24/min being supporte

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Which Anticoagulant Is Safest for Afib Patients With Cirrhosis?

Med Page Today

(MedPage Today) -- Apixaban (Eliquis) was associated with lower serious bleeding rates than rivaroxaban (Xarelto) or warfarin in patients with cirrhosis and atrial fibrillation (AF, Afib) in a nationwide cohort study. Among more than 12,000 such.

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Delaying diabetes with diet and exercise for four years results in better long-term health

Science Daily - Heart Disease

Individuals diagnosed with prediabetes can reduce their long-term risk of death and diabetes-related health complications if they delay the onset of diabetes for just four years through diet and exercise, according to new findings.

Diet 105
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HeartSciences Announces Allowance of U.S Patent for AI-ECG Assessment of Left Ventricular and Right Ventricular Heart Dysfunction

DAIC

mtaschetta-millane Thu, 07/11/2024 - 10:53 July 11, 2024 — Heart Test Laboratories, Inc. an artificial intelligence (AI)-powered medical technology company focused on transforming ECGs/EKGs to save lives through earlier detection of heart disease, announced that intellectual property (IP) exclusively licensed to HeartSciences has received a notice of allowance from the United States Patent and Trademark Office (USPTO) for the detection of left ventricular (LV) and/or right ventricular (RV) dys

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A little more on the trial

Dr. Malcolm Kendrick

11th July 2024 As regular readers will know, Zoë Harcombe and I sued the Mail on Sunday (Associated Newspapers) and Barney Calman for libel. This is a saga that began over five years ago. Which has explained much of my recent silence on this blog, following a hearing in July last year. We won on almost all points. Some of them very technical. The entire judgment can be seen here [link] Here is one part, section 509 “Before turning to the remaining issues, I should repeat that the exercise of det

Article 106
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Sarcopenia and aortic valve disease

Heart BMJ

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR). Despite improvements in outcomes, older adults with competing comorbidities and geriatric syndromes have suboptimal quality of life outcomes, highlighting the cumulative vulnerability that persists despite val

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Ep 196 Pediatric Meningitis Recognition, Workup and Management

ECG Cases

In this episode: recognition, risk stratification, decision tools, indications for lumbar puncture in the febrile pediatric patient, tips and trick on performing LPs in children, and ED management of pediatric meningitis. We answer such questions as: what are the test characteristics of the various clinical features of meningitis across various ages?

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Step Into the Cardiology Clinic of the Future: Bringing Virtual Cardiac Care Delivery and Virtual Telemetry to Life in Your Practice’s Clinical Workflows

DAIC

In a room of 20 people, it’s likely that about 10 of them, or half, will presently have some form of cardiovascular disease (CVD). CVD is among the most prevalent diseases in the U.S., and strokes and other CVDs are on the rise globally. One report projects a 50% increase in stroke-related deaths by 2050, with 10 million dying annually. Atrial fibrillation (AFib) cases have also surged, doubling from 28.3 million in 1990 to 56.7 million in 2019.

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JAK Inhibitors May Reduce AMD Onset in Autoimmune Diseases

HCPLive

Administrative claims database analysis revealed a lower AMD incidence in patients treated with JAK inhibitor therapy versus non–JAK-based immunotherapy.

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Tirzepatide Bests Semaglutide for Real-World Weight Loss

Med Page Today

(MedPage Today) -- In formulations indicated for type 2 diabetes, tirzepatide (Mounjaro) yielded more weight loss than semaglutide (Ozempic) in people with overweight or obesity, according to real-world data. In the first 3 months on treatment.

Obesity 115
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How A New Cardiovascular Suite is Strengthening the Heart of Community Healthcare in Iowa

Cassling

Time is muscle. This common phrase is well-known to healthcare providers in the ED who have been called upon to treat a heart attack. The longer you take to stabilize the heart, the higher the risk of long-term damage to the patient’s heart. "Time is muscle” was the impetus for the new $6 million cardiovascular suite at Methodist Jennie Edmundson Hospital in Council Bluffs, Iowa.

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R3 Vascular Appoints Josh Smale as Vice President of Global Clinical and Scientific Affairs

DAIC

Medical device company R3 Vascular Inc., a Mountain View, CA-based developer of novel, best-in-class bioresorbable scaffolds for treating peripheral arterial disease (PAD), has announced the appointment of Josh Smale as its Vice President of Global Clinical and Scientific Affairs. Image courtesy: R3 Vascular Inc. christine.book Thu, 07/11/2024 - 10:50 July 11, 2024 — Medical device company R3 Vascular Inc. , developer of novel, best-in-class bioresorbable scaffolds for treating peripheral arteri

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Alternative understanding of brain leads to new treatments for stroke patients

Medical Xpress - Cardiology

Since the early 20th century, researchers believed that movements on the right and left sides of the body were controlled by the opposite hemisphere of the brain and that handedness resulted from the dominant side doing a better job at controlling movements.

Stroke 92
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Dose Reduction of Edoxaban in Older Patients With Atrial Fibrillation

JAMA Cardiology

This post hoc analysis of a randomized clinical trial investigates if patients 80 years and older with atrial fibrillation benefit from lower-dose anticoagulants even in the absence of prespecified dose-reduction criteria.

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Anxiety, Depression Interfere with Preventive Actions to Reduce CVD Risk Factors

HCPLive

A study showed participants with symptoms of anxiety and depression had significantly fewer controlled cardiovascular disease risk factors.

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Amvia Sky Launched in Canada, the World’s First Pacemaker Approved for LBBAP

DAIC

mtaschetta-millane Thu, 07/11/2024 - 11:01 July 11, 2024 — Dr. Fadi Mansour performed the first Canadian implant of BIOTRONIK ’s newest pacemaker and CRT-P generation earlier this year at the Centre Hospitalier de l'Université de Montréal. The patient received an Amvia Sky HF-T QP triple chamber pacemaker device. The first implant follows the full market release of BIOTRONIK’s newest family of pacemaker and CRT-P devices, featuring patient-centric technologies for better patient care and simp

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Study elucidates mechanism behind cardiac fibrosis, opening way for new heart failure treatments

Medical Xpress - Cardiology

Cardiovascular disease often culminates in heart failure, a hallmark of which is fibrosis, a form of tissue scarring. Cardiac fibrosis initially repairs damaged heart tissue, but it can quickly become excessive and pathological. Identifying the mechanisms behind fibrosis is a focal point in cardiovascular research, and now scientists at the Lewis Katz School of Medicine at Temple University have discovered a critical genetic mechanism driving the process—and they have identified a novel target f

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See how bad the outcome can be if you don't know OMI findings on the ECG, and don't use the Queen of Hearts

Dr. Smith's ECG Blog

This is another case sent by the undergraduate (who is applying to med school) who works as an EKG tech. How is it possible that a kid who has not even started medical school can know so much about EKGs and cardiology? Because: 1) He has been reading this blog for a long time. 2) He is curious This is how Pendell got started. Case A 43 year old male with a history of DM II, hyperlipidemia, and a family history of myocardial infarction presented to a family clinic with two days of epigastric pain

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Mediterranean Diet Linked to Improved Markers of Cardiometabolic Health in Children, Adolescents

HCPLive

Promoting adherence to a Mediterranean diet in children improves cardiometabolic health biomarkers, according to a new study.

Diet 111
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CellProthera and BioCardia Collaborate on Successful Phase II Trial of ProtheraCytes for the Treatment of Acute Myocardial Infarction

DAIC

mtaschetta-millane Wed, 07/10/2024 - 09:02 July 10, 2024 — CellProthera , a private company specializing in cell-based therapies for repairing ischemic tissues, and BioCardia, Inc. , a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, announced success from a collaborative Phase II trial of ProtheraCytes for the treatment of acute myocardial infarction (AMI) led by CellProthera , as well as plans to continue the relationship into Pha

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Journal Club 6 Which Older Patients Can Safely Forgo CT Head After a Fall? The Falls Decision Rule

ECG Cases

The decision of whether or not to order a CT head for an older patient who falls is one I need to make on almost every shift. The Canadian CT Head Rule does not apply to older patients. Does the recently derived Falls Decision Rule give us an answer to the question of which older patients can safely forego a CT head after a fall? Dr. Rohit Mohindra reviews the latest evidence in this EM Cases Journal Club.

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Molecular atlas of blood vessel pathways in the human brain, across early brain development, adulthood and disease

Science Daily - Stroke

Researchers have built the first-ever molecular atlas of the human brain vasculature at single-cell resolution, spanning from early development to adulthood and through disease stages such as brain tumors and brain vascular malformations.

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Differences in Binding Affinity Between Integrase Inhibitors in HIV

HCPLive

An infectious disease specialist discusses the differences in binding affinity between dolutegravir and bictegravir and how it informs treatment selection.

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