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This patient was seen in the office — and during his exam, was found to have an “irregular heart beat”. He was not symptomatic with the ECG shown in Figure-1. How would YOU interpret this ECG? As the primary care clinician — What would YOU do? Extra Credit ( which is a HINT to the Answer! ): How many beats are recorded on the ECG in Figure-1 ? Figure-1: The initial ECG in today’s case. ( To improve visualization — I've digitized the original ECG using PMcardio ).
Investigators from Brigham and Women's Hospital and Keio University in Japan have developed a deep learning artificial intelligence model to screen electrocardiogram (ECG) for signs of atrial septal defects (ASD). This condition can cause heart failure and is underreported due to a lack of symptoms before irreversible complications arise. Their results are published in eClinicalMedicine.
Objectives To determine baseline characteristics predictive of left ventricular ejection fraction (LVEF) recovery in patients diagnosed with heart failure with reduced ejection fraction (HFrEF) and presumed non-ischaemic aetiology. Methods We prospectively recruited patients who were diagnosed with HFrEF (LVEF ≤40%) on echocardiography and subsequently underwent cardiac MRI.
Throughout our 65-year history at CTVS, we have always been proud to assemble the most talented team of cardiothoracic and vascular surgeons in Central Texas. We are thrilled to announce the addition of a new member to our team vascular surgeon Dr. Kofi B. Quaye who will begin seeing patients in September. Dr.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Are you getting ready to open, or currently operating, an Office-Based Lab (OBL) or Ambulatory Surgery Center (ASC)? When you’re unable to rely on hospital administration or a purchasing manager to oversee the business end of your practice, including purchasing, service contracts, staffing, reimbursement and more, it’s imperative that you keep costs contained while simultaneously investing in equipment that will stand the test of time, supported by a reliable, all-encompassing service contract.
Wearable devices often pick up noisy electrocardiograms (ECGs), which can hinder artificial intelligence (AI)-based detection of cardiovascular disease.
Background Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab and their correlations with neutrophils, C-reactive protein (CRP), troponin T, MSI and infarct size. Methods STEMI patients were randomised to receive a single dose of 280 mg tocilizumab (n=101) or placebo (n=98) before percutaneous coronary intervention.
Background Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab and their correlations with neutrophils, C-reactive protein (CRP), troponin T, MSI and infarct size. Methods STEMI patients were randomised to receive a single dose of 280 mg tocilizumab (n=101) or placebo (n=98) before percutaneous coronary intervention.
Heart disease remains a prevalent and serious health concern that affects millions worldwide. Understanding the risk factors, recognizing the signs and seeking guidance from a cardiologist can play a significant role in preventing and treating this disease. Below, the heart doctors at AMS Cardiology explain who’s at risk and the signs of a cardiovascular problem and highlight why it’s necessary to seek help from a cardiologist for optimal heart health.
Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant. Subscribe now Take cardiovascular disease, for example. With no insulin resistance and high APOB (LDL-C), the risk of future heart events increases by about 80%.
Research Matters. Conquering CHD exists to conquer the most common birth defect. As an organization made up entirely of CHD patients, families, and medical experts, we build knowledge, create visibility, and empower all impacted by congenital heart disease. One way that Conquering CHD achieves our mission is to champion patient engaged research. We do this through advocacy, consultation, collaboration, and direct funding.
Objectives Two interlinked surveys were organised by the British Heart Foundation Data Science Centre, which aimed to establish national priorities for cardiovascular imaging research. Methods First a single time point public survey explored their views of cardiovascular imaging research. Subsequently, a three-phase modified Delphi prioritisation exercise was performed by researchers and healthcare professionals.
Written by Pendell Meyers, with some edits by Smith A man in his 40s with many comorbidities presented to the ED with chest pain, hypotension, dyspnea, and hypoxemia. The bedside echo showed a large RV (Does this mean there is a pulmonary embolism as the etiology?) Here is his triage ECG: What do you think? Lots of info here. The rhythm is 2:1 atrial flutter.
The Tachycardia starts with a premature broad QRS-complex. We see nonconducted Sinus-P-waves. There are more QRS than P, so it is AV-dissociation. There is no doubt that there is a VT prestent here.
Infection is the most dreaded complication of cardiac implantable electronic devices (CIEDs), particularly in patients undergoing high-risk procedures (eg, generator change, device upgrade, lead/pocket revision).
Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 496-506, October 1, 2023. Previous studies on cardiomyopathies have been particularly valuable for clarifying pathological mechanisms in heart failure, an etiologically heterogeneous disease. In this review, we specifically focus on cardiomyopathies in Asia, where heart failure is particularly pertinent.
Introduction Systemic low-grade inflammation is a fundamental pathophysiological mechanism of heart failure with preserved left ventricular ejection fraction (HFpEF). The efficacy of anti-inflammatory therapy in HFpEF is largely understudied. The aim of the study is to assess the anti-inflammatory effect of colchicine in HFpEF by looking at inflammatory biomarkers: high-sensitivity C reactive protein (hsCRP) and soluble suppression of tumorigenicity 2 (sST2).
Stroke: Vascular and Interventional Neurology, Ahead of Print. Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that results in painless vision loss attributable to retinal infarction. A keen understanding of clinical presentation and underlying pathophysiological features is key to timely intervention and development of new treatment modalities.
The direct oral anticoagulant (DOAC) dabigatran is a p-glycoprotein (P-gp) substrate, whereas rivaroxaban and apixaban are substrates of both P-gp and cytochrome P-450 enzymes (CYP).1 Inhibitors of CYP and P-gp increase DOAC serum concentrations and have the potential to increase the risk for bleeding events.1 The nondihydropyridine calcium channel blockers (non-DHP CCB) diltiazem and verapamil are heart rate control medications that potentially interact with DOACs via CYP/P-gp substrate inhibit
Stroke: Vascular and Interventional Neurology, Ahead of Print. Acute stroke management has become increasingly complex, incorporating medical, endovascular, and open surgical treatments that are potentially implemented across multiple hospitals for the same patient. Hospitals work in ever‐expanding networks to provide cost‐effective stroke care, balancing capital and labor costs, expertise, and catchment reach.
Objective To characterise cardiac remodelling, exercise capacity and fibroinflammatory biomarkers in patients with aortic stenosis (AS) with and without diabetes, and assess the impact of diabetes on outcomes. Methods Patients with moderate or severe AS with and without diabetes underwent echocardiography, stress cardiovascular magnetic resonance (CMR), cardiopulmonary exercise testing and plasma biomarker analysis.
Lying in a hospital bed, waiting to be scheduled for a pacemaker implant, I realized the irony that I would be the recipient of the innovations I was instrumental in initially developing more than 50 years ago.
A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients has shown that using DBS to target the dentate nucleus -- which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain -- is safe and feasible.
Introduction Electrocardiogram (ECG) machines are vital in diagnosing and monitoring various cardiac conditions. As these devices become increasingly integrated into healthcare systems, ensuring machines’ safety, performance, and compliance with regulatory standards becomes paramount. ECG machine certification is crucial in achieving these goals and building trust among healthcare providers and patients.
Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 434-441, October 1, 2023. BACKGROUND:Variants inRBM20are reported in 2% to 6% of familial cases of dilated cardiomyopathy and may be associated with fatal ventricular arrhythmia and rapid heart failure progression. We sought to determine the risk of adverse events inRBM20variant carriers and the impact of sex on outcomes.METHODS:Consecutive probands and relatives carryingRBM20variants were retrospectively recruited from 12 ca
Ventricular repolarization dispersion derives from heterogeneities in action potential duration (APD) and its associated effective refractory period (ERP) across ventricular walls, between the left and right ventricles, and between the apex and the base of the ventricles.1,2 Enhanced dispersion of repolarization under a variety of pathological conditions may serve as substrates for functional reentry leading to life-threatening polymorphic ventricular tachycardia (VT) or ventricular fibrillation
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