Ken Grauer, MD
SEPTEMBER 22, 2023
The ECG in Figure-1 — was obtained from a middle-aged man with palpitations and shortness of breath. He was hemodynamically stable at the time this tracing was recorded. How would YOU interpret the ECG in Figure-1 ? Is there evidence of a recent or ongoing acute MI? What might you do first? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ).
Dr. Smith's ECG Blog
SEPTEMBER 19, 2023
Case submitted by anonymous. Written by Smith. Ken's piece at the bottom is excellent. A 50-something presented with s udden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued. Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest.
International Journal of Cardiovascular Sciences
SEPTEMBER 21, 2023
Access below the articles from the thematic collection on Cardiometablism. Responsible editor: Ricardo Mourilhe Rocha Original Articles: One Size Does Not Fit All: The Need to Rethink the Metabolic Syndrome in Women Association of Dietary Inflammatory Potential in Metabolically Healthy and Metabolically Unhealthy Obese Individuals High Cardiorespiratory Optimal Point Values Are Related to Cardiovascular Mortality in Men Aged 46 to 70 Years: a Prospective Cohort Study The Relationship between Bas
American Heart News - Stroke News
SEPTEMBER 21, 2023
DALLAS and MINNEAPOLIS, Sept. 21, 2023 – In an effort to increase understanding, prevention and treatment of brain disease, the American Heart Association (the Association) and the American Academy of Neurology (AAN) today launched a scholarship.
ADN Center of Excellence
SEPTEMBER 20, 2023
Medicine is both a science and an art. While the scientific knowledge and technological advancements in the field have undoubtedly revolutionized healthcare, the art of medicine, often referred to as the "healing touch," remains equally important. Doctors who possess exceptional clinical skills and a deep understanding of the human body's intricacies can make a significant difference in their patients' lives.
Dr. Smith's ECG Blog
SEPTEMBER 22, 2023
This ECG was texted to me with no other information. I assumed the presentation was consistent with acute MI. What did I say? "OMI. Activate the cath lab." The T-waves in V2-V6 are diagnostic. It does, in fact, the STE meets STEMI criteria since there is 1 mm of in V4 and V5. There is also some non-diagnostic STE in inferior leads. There is zero reciprocal ST depression. 50% of LAD OMI have zero reciprocal ST depression!
Dr. Paddy Barrett
SEPTEMBER 19, 2023
I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. The answer is: No. Statins do not cause dementia. Share If you do not read any further, you will have come away with the main takeaway of this article. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Heart Sisters
SEPTEMBER 17, 2023
Oh, no! I ran out of time to tell those med students about how pregnancy complications are strongly linked to later heart disease!
Dr. Smith's ECG Blog
SEPTEMBER 17, 2023
Written by Magnus Nossen MD, peer reviewed and edits by Smith, Meyers, Grauer A 60 something previously healthy female smoker sought medical attention after 2-3 days of intermittent chest discomfort. The chest discomfort was described as sharp. Episodes lasting 5-30 minutes. On the day of presentation she experienced another episode of chest discomfort accompanied by vomiting and throat pain.
HeartRhythm
SEPTEMBER 21, 2023
The Micra AV Coverage with Evidence Development (CED) study is a novel analysis of utilization and outcomes associated with Micra AV leadless pacing among US Medicare patients.
Science Daily - Heart Disease
SEPTEMBER 22, 2023
Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms underlying the disease, and offers new tools for their prevention.
Hypertension Journal
SEPTEMBER 21, 2023
Hypertension, Ahead of Print. Dementia affects almost 50 million adults worldwide, and remains a major cause of death and disability. Hypertension is a leading risk factor for dementia, including Alzheimer disease and Alzheimer disease–related dementias. Although this association is well-established, the mechanisms underlying hypertension-induced cognitive decline remain poorly understood.
Journal of Cardiovascular Pharmacology
SEPTEMBER 19, 2023
Venous thromboembolism (VTE) is a prevalent yet preventable cause of death, particularly among hospitalized patients. Studies have shown that the risk of VTE remains high for up to 6 months after discharge, highlighting the need for extended thromboprophylaxis as a viable treatment approach. Despite the availability of several anticoagulant drugs like vitamin K antagonists, heparinoids, rivaroxaban, apixaban, edoxaban, and dabigatran, none of them has received approval from the US Food and Drug
HeartRhythm
SEPTEMBER 21, 2023
Long QT syndrome (LQTS) is the most common and most well established genetic arrhythmia syndrome/primary electrical disease, caused by pathogenic disease–causative variants in genes that encode either the critical alpha subunits or channel interacting proteins of the heart’s ion channels that are directly or indirectly involved in the repolarization process.1,2 The diagnosis of LQTS relies on prolongation of the heart rate corrected QT (QTc) interval, which together with a number of other electr
Open Heart
SEPTEMBER 19, 2023
Background The COVID-19 pandemic disrupted the continuing management of cardiovascular disease (CVD) risk factors in the population. Socioeconomic status (SES) is a major determinant of health. Whether the COVID-19 pandemic increased, the SES gap in CVD risk factors is unknown. Aims To compare the management of CVD risk factors and the SES gap before and during the pandemic.
Hypertension Journal
SEPTEMBER 21, 2023
Hypertension, Ahead of Print. There has been considerable progress in the prevention and treatment of cardiovascular disease, reducing the population burden of cardiovascular morbidity and mortality. Recently, some randomized trials, including the SPRINT (Systolic Blood Pressure Intervention Trial), have suggested that improvements in cardiovascular risk factors may also slow cognitive decline and reduce the eventual development of dementia.
CTVS
SEPTEMBER 20, 2023
Peripheral Artery Disease, or PAD, is a serious circulatory condition that is steadily on the rise. In the United States, 23.8 million people are expected to be diagnosed with PAD by 2030. At CTVS, we frequently treat the many complications stemming from PAD. This PAD Awareness Month, we’re sharing some important things to know about the condition.
HeartRhythm
SEPTEMBER 20, 2023
Conduction system pacing (CSP) is a promising new approach for delivering pacing therapy.1 CSP offers an elegant treatment solution to the challenging problem of heart failure (HF) caused by electrical dyssynchrony due to left bundle branch block (LBBB). Pacing therapy of LBBB-caused electrical dyssynchrony has a long and successful history. Cardiac resynchronization therapy improves survival and quality of life and reduces HF hospitalizations in HF patients with LBBB.1 Striving to improve patie
Science Daily - Heart Disease
SEPTEMBER 19, 2023
Men exposed to stressful working conditions who also felt that they put forth high effort but received low reward had twice the risk of heart disease compared to men who were free of those psychosocial stressors.
Hypertension Journal
SEPTEMBER 21, 2023
Hypertension, Ahead of Print. Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. While often attributed to midlife vascular risk factors such as hypertension, factors from earlier in life may contribute to later small vessel disease risk. In this review, we summarize current evidence for early-life effects on small vessel disease, stroke and dementia focusing on prenatal nutrition, and cognitive ability, education, and so
Journal of Cardiovascular Electrophysiology
SEPTEMBER 19, 2023
Abstract Premature ventricular complexes (PVCs) are encountered frequently in clinical practice. While PVCs may have various causes, a small number of individuals with PVCs develop cardiomyopathy in the absence of other potential etiologies. When correctly identified, patients with PVC-incuded cardiomyopathy can have dramatic improvement of their cardiomyopathy with treatment of their PVCs.
HeartRhythm
SEPTEMBER 20, 2023
Electrocardiographic (ECG)-based criteria are used to confirm left bundle branch (LBB) pacing (LBBP), but current cut-off values have never been validated for different pacing locations.
European Journal of Heart Failure
SEPTEMBER 18, 2023
ABSTRACT Aims Takotsubo syndrome (TTS) is associated with a substantial rate of adverse events. We sought to design a machine learning (ML)-based model to predict the risk of in-hospital death and to perform a clustering of TTS patients to identify different risk profiles. Methods and results A ridge logistic regression-based ML model for predicting in-hospital death was developed on 3482 TTS patients from the International Takotsubo (InterTAK) Registry, randomly split in a train and an internal
Hypertension Journal
SEPTEMBER 18, 2023
Hypertension, Ahead of Print. Salt (sodium chloride) is an essential nutrient required to maintain physiological functions. However, for most people, daily salt intake far exceeds their physiological need and is habitually greater than recommended upper thresholds. Excess salt intake leads to elevation in blood pressure which drives cardiovascular morbidity and mortality.
Open Heart
SEPTEMBER 20, 2023
Background Computer-assisted interpretation of single-lead ECG is the preliminary method for clinicians to flag and further evaluate an arrhythmia of clinical importance for acutely ill patients. Critical scrutiny of novel detection algorithms is lacking, particularly in external real-world data sets. This study’s objective was to evaluate a hybrid machine learning model’s ability to classify eight arrhythmias from a single-lead ECG signal from acutely ill patients.
HeartRhythm
SEPTEMBER 19, 2023
Conflicting data are available on whether ventricular arrhythmia (VA) or shock therapy increases mortality. Though cardiac resynchronization therapy (CRT) reduces the risk of VA, little is known about the prognostic value of VA among patients with CRT devices.
European Journal of Heart Failure
SEPTEMBER 18, 2023
Summary of the development, validation, and clinical application of the LIFEtime-perspective for Heart Failure (LIFE-HF) model. ACEi, angiotensin-converting enzyme inhibitor; ARNI, angiotensin receptor–neprilysin inhibitor; BB, beta-blocker; HF, heart failure; HFH, heart failure hospitalization; HFrEF, heart failure with reduced ejection fraction; LVEF, left ventricular ejection fraction; MRA, mineralocorticoid receptor antagonist; NT-proBNP, N-terminal pro-B-type natriuretic peptide; NYHA, New
HeartRhythm
SEPTEMBER 19, 2023
In patients with hypertrophic cardiomyopathy (HCM), atrial fibrillation (AF) poses significant clinical challenges because of its adverse impact on hemodynamics. AF, especially when accompanied by rapid ventricular responses, compromises atrial contraction and in turn increases diastolic filling of the left ventricle. This often exacerbates, or even precipitates, heart failure—an effect that is especially pronounced in the presence of concurrent left ventricular outflow tract obstruction.1 In ad
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