Sat.Dec 02, 2023 - Fri.Dec 08, 2023

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ECG Video Blog #407 (292): Why the Patient Died?

Ken Grauer, MD

== CLICK HERE — for a V ideo presentation of this case! (22:3 0 min. ) Below are slides used in my video presentation. For full discussion of this case — See ECG Blog #292 — == The 2 ECGs shown in Figure-1 were obtained from a man in his 30s — who presented to the ED ( E mergency D epartment ) with chest pain that began several hours earlier. ECG #2 was recorded 1 hour after ECG #1.

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Blood Test May Be Able to Tell Which Organs Have Accelerated Aging

Med Page Today

(MedPage Today) -- About one in five healthy people ages 50 and older had an organ that was aging at an accelerated rate, which may increase mortality and signal organ-specific disease, a study of nearly 5,700 people suggested. In an analysis.

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New study finds many couples around the world may share high blood pressure

American Heart News - Heart News

Research Highlights: A study of married or partnered, middle-aged and older heterosexual couples in the U.S., England, China and India found that in 20% to 47% of the couples, both spouses/partners had high blood pressure. The prevalence of both.

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What’s wrong with the NHS? – Part 4

Dr. Malcolm Kendrick

8th December 2023 Nothing can simply be ‘good enough’. Before beginning this blog, I thought I would introduce you to the first two laws of regulation ‘ regulation-omics’ : I know that many of the things that are obliterating productivity in the NHS are happening in all health care services, everywhere. A couple of blogs back I mentioned a US study which looked at all the guidelines primary care practitioners (PCPs) are now required to follow.

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OMI in a pediatric patient? Teenagers do get acute coronary occlusion, so don't automatically dismiss the idea.

Dr. Smith's ECG Blog

Acute coronary syndrome in a pediatric patient? Written by Kirsten Morrissey, MD with edits by Bracey, Grauer, Meyers, and Smith An older teen was transferred from an outside hospital with elevated serum troponin and and ECG demonstrating ST elevations. The patient was obese and had a medical history of only recurrent tonsillitis status post tonsillectomy and adenoidectomy but was otherwise healthy and fully vaccinated.

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Spontaneous Coronary Artery Dissections: Treatment Recommendations Still Unheeded

Med Page Today

(MedPage Today) -- Consensus recommendations for spontaneous coronary artery dissection (SCAD) have been applied inconsistently despite increasing awareness of this condition, according to a meta-analysis. Observational studies showed significant.

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Procyrion Announces First Patient Enrollments in the DRAIN-HF Pivotal IDE Trial for Aortix Percutaneous Mechanical Circulatory Support Technology

DAIC

The DRAIN-HF study will evaluate the Aortix percutaneous mechanical circulatory support (pMCS) technology in patients with acute decompensated heart failure (ADHF) who are unresponsive to standard medical therapy. milla1cf Fri, 12/08/2023 - 08:07 December 8, 2023 — Procyrion, Inc. , a medical device company dedicated to improving outcomes for patients with cardiac and renal impairment, announced the enrollment of the first patients in the company's IDE pivotal trial.

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Webinar: Beyond STEMI: Diagnosing Acute Coronary Occlusion on the ECG. The Queen of Hearts can do it for you!!

Dr. Smith's ECG Blog

Beyond STEMI: Diagnosing Acute Coronary Occlusion on the ECG. The Queen of Hearts AI app can do it for you. With explainability too.

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More Awareness Needed of Heart Events Tied to Breast Cancer Drugs, Experts Say

Med Page Today

(MedPage Today) -- Pharmacovigilance is needed to identify, monitor, and prevent cardiovascular adverse events (CV-AEs) associated with new agents for breast cancer and to reduce the risk of cardiotoxicity for the growing number of survivors, according.

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AHA 2023 Highlights

Cardiology Update

Dr. Chadi Alraies discusses highlights from the American Heart Association (AHA) Scientific Sessions 2023, which were held in Philadelphia, Pennsylvania (PA), on November 11-13, 2023. There were many important developments in presented in key clinical trial presentations and publications stemming from the AHA Scientific Sessions 2023. Learn more about AHA 2023 highlights.

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BNP level predicts bleeding event in patients with heart failure after percutaneous coronary intervention

Open Heart

Objective This study aimed to investigate the association between heart failure (HF) severity measured based on brain natriuretic peptide (BNP) levels and future bleeding events after percutaneous coronary intervention (PCI). Background The Academic Research Consortium for High Bleeding Risk presents a bleeding risk assessment for antithrombotic therapy in patients after PCI.

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"A patient just arrived as a transfer for NSTEMI."

Dr. Smith's ECG Blog

Written by Willy Frick The OMI paradigm has taught me that any diagnosis of NSTEMI is cause for immediate evaluation. "A patient just arrived as a transfer for NSTEMI." I quickly reviewed the patient’s records and saw that she was a 53 year old woman with a history of BMI 40, but no other identifiable risk factors for coronary artery disease. Her first hsTnI at the referring facility was undetectable.

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JAK Inhibitor Preserves Beta-Cell Function in Early Type 1 Diabetes

Med Page Today

(MedPage Today) -- A Janus kinase (JAK) inhibitor helped preserve beta-cell function in people with recent-onset type 1 diabetes, the phase II BANDIT trial found. Meeting the study's primary endpoint, daily baricitinib (Olumiant) maintained a.

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Utilize Easy-to-Use Radiology Image Sharing Tech (Ditch the CDs)

NOVARAD

In the past, CDs played a central role in the storage and dissemination of radiology images. The medical community was largely dependent on these physical media, a practice that while operational, was beset with obstacles related to storage, reach, and expenses. But as is characteristic of technology, transformation is constant. A migration toward more streamlined and economically viable options for handling and circulating these essential images is underway.

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Prognostic impact of lung ultrasound detected B-lines on hospitalised ischaemic heart failure with mildly reduced ejection fraction patients

Open Heart

Objectives Prognostic impact of lung ultrasound-derived B-lines (LUS-BL) in heart failure with mildly reduced left ventricular ejection fraction (HFmrEF) patients remains elusive. We evaluated the correlation between LUS-BL and prognosis in HFmrEF patients. Methods This is a subgroup analysis based on our previously published retrospective study with 1691 HFmrEF patients.

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Plant-based Diets and Exercise Performance

Physiologically Speaking

“Eat food. Not too much. Mostly plants.” This quippy dietary advice comes from author Michael Pollan in his book “In Defense of Food.” Most people would agree with the first two imperatives but not the last. Indeed, one of the most controversial topics in health and nutrition is whether one should include or exclude — or at the very least limit — animal foods from their diet.

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Transplant Advocates Sound Alarm Over Proposed Medicare Test Coverage Policy

Med Page Today

(MedPage Today) -- WASHINGTON -- Heart transplant patient Eddie Garcia was "feeling like a million bucks" one day in the summer of 2021. He had just gotten back from a 3-mile walk, something he couldn't do prior to his transplant in 2020 -.

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Resistance Exercise Training in Individuals With and Without Cardiovascular Disease: 2023 Update: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Resistance training not only can improve or maintain muscle mass and strength, but also has favorable physiological and clinical effects on cardiovascular disease and risk factors. This scientific statement is an update of the previous (2007) American Heart Association scientific statement regarding resistance training and cardiovascular disease.

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Familial risk of vasospastic angina: a nationwide family study in Sweden

Open Heart

Objectives Vasospastic angina (VSA) is a complex coronary vasomotor disorder associated with an increased risk of myocardial infarction and sudden death. Despite considerable advances in understanding VSA pathophysiology, the interplay between genetic and environmental factors remains elusive. Accordingly, we aimed to determine the familial VSA risk among first-degree relatives of affected individuals.

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Sudden ST-Segment Changes in a Critically Ill Patient

JAMA Cardiology

A patient in his mid-60s underwent bilateral orthotopic lung transplant and is later hospitalized for sepsis from pneumonia complicated by acute transplant rejection, without any cardiac symptoms. He develops severe acute respiratory distress syndrome requiring intubation and paralysis. Electrocardiography shows sudden ST-segment changes. What would you do next?

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Pharmacists Can Spur Switch to Recommended Drugs for Diabetes Patients With CVD

Med Page Today

(MedPage Today) -- ANAHEIM, Calif. -- A pharmacist-led intervention using notes in the electronic health record (EHR) proved effective for convincing primary care providers to switch veterans with diabetes and cardiovascular disease (CVD) to.

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Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure: The DETERMINE Randomized Clinical Trials

Circulation

Circulation, Ahead of Print. BACKGROUND:Sodium-glucose cotransporter 2 inhibitors reduce the risk of worsening heart failure (HF) and cardiovascular death in patients with HF irrespective of left ventricular ejection fraction. It is important to determine whether therapies for HF improve symptoms and functional capacity.METHODS:The DETERMINE (Dapagliflozin Effect on Exercise Capacity Using a 6-Minute Walk Test in Patients With Heart Failure) double-blind, placebo-controlled, multicenter trials a

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An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease

Cardiovascular Diabetology

Insulin resistance is a pivotal risk factor for cardiovascular diseases, and the triglyceride-glucose (TyG) index is a well-established surrogate of insulin resistance. This study aimed to investigate the prog.

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Risk Prediction for Atherosclerotic Cardiovascular Disease With and Without Race Stratification

JAMA Cardiology

This cohort study investigates the association between removal of race stratification from the atherosclerotic cardiovascular pooled cohort risk equations and model performance.

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High Blood Pressure in Babies Linked to Adult Atherosclerosis

Med Page Today

(MedPage Today) -- The link between childhood blood pressure (BP) and adult atherosclerosis appeared stable going all the way back to infancy, suggesting that efforts to prevent arterial thickening may be beneficial starting at the earliest life.

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Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies

Circulation

Circulation, Ahead of Print. BACKGROUND:It is unknown whether dietary intake of polyunsaturated fatty acids (PUFA) modifies the cardiovascular disease (CVD) risk associated with a family history of CVD. We assessed interactions between biomarkers of low PUFA intake and a family history in relation to long-term CVD risk in a large consortium.METHODS:Blood and tissue PUFA data from 40 885 CVD-free adults were assessed.

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Time Window for Induced Hypertension in Acute Small Vessel Occlusive Stroke With Early Neurological Deterioration

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:Therapeutic-induced hypertension treatment (iHTN) is helpful for alleviating early neurological deterioration (END) in acute small vessel occlusive stroke. We examined the time parameters related to iHTN effectiveness in these patients.METHODS:We retrospectively reviewed patients with acute small vessel occlusive stroke who underwent iHTN for END, defined as an increase of ≥2 points in total National Institutes of Health Stroke Scale (NIHSS) score or ≥1 point i

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Intention to Treat: Is Xenotransplantation Ready for Prime Time? — ITT Episode 22

The New England Journal of Medicine

This podcast episode examines the need for and promise of xenotransplantation, considering first the plight of patients and then the progress being made by researchers.

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Inappropriate Aspirin Use Continues, Research Suggests

Med Page Today

(MedPage Today) -- ANAHEIM, Calif. -- Some patients may be taking aspirin inappropriately, two single-center retrospective studies found. In the first study, conducted at general medicine units at an academic medical center, 93 of 225 patients.

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Update on Cardiovascular Implantable Electronic Device Infections and Their Prevention, Diagnosis, and Management: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. The American Heart Association sponsored the first iteration of a scientific statement that addressed all aspects of cardiovascular implantable electronic device infection in 2010. Major advances in the prevention, diagnosis, and management of these infections have occurred since then, necessitating a scientific statement update.

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Endovascular catheter opens blocked arteries deep within lungs

Science Daily - Heart Disease

A new endovascular catheter, recently approved by the U.S. Food and Drug Administration (FDA), is paving the way to more effective and safe treatment for acute pulmonary embolism. Already shown to be effective for reducing blockages in lung arteries, new research shows that this catheter also reduces blockages in the smaller segmental pulmonary artery branches.

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Spousal Concordance of Hypertension Among Middle?Aged and Older Heterosexual Couples Around the World: Evidence From Studies of Aging in the United States, England, China, and India

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundHealth concordance within couples presents a promising opportunity to design interventions for disease management, including hypertension. We compared the concordance of prevalent hypertension within middle‐aged and older heterosexual couples in the United States, England, China, and India.Methods and ResultsCross‐sectional dyadic data on heterosexual couples were used from contemporaneous waves of the HRS (US Health and Retire

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Cost Hurdles Can Keep Patients From Accessing GLP-1 Receptor Agonists

Med Page Today

(MedPage Today) -- ANAHEIM, Calif. -- Insurance coverage and out-of-pocket costs for GLP-1 receptor agonists pose serious barriers to patients prescribed these drugs for type 2 diabetes and other indications, two single-site studies showed.

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Cardiac Abnormalities in Hispanic/Latina Women With Prior De Novo Hypertensive Disorders of Pregnancy

Hypertension Journal

Hypertension, Ahead of Print. Background:Hypertensive disorders of pregnancy (HDP) are associated with long-term maternal risks for cardiovascular disease for reasons that remain incompletely understood.Methods:The HCHS/SOL (Hispanic Community Health Study/Study of Latinos), a multi-center community-based cohort of Hispanic/Latino adults recruited 2008 to 2011, was used to evaluate the associations of history of de novo HDP (gestational hypertension, preeclampsia, eclampsia) with echocardiograph

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Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study

Cardiovascular Diabetology

Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the glucagon-like peptide-1 receptor (GLP-1R) has been suggested to induce several effects.

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Weill Cornell finds race doesn't impact cardiovascular risk

Becker's Hospital Review - Cardiology

A Weill Cornell Medicine and NewYork-Presbyterian study found removing race information from cardiovascular risk calculators did not affect patients' risk scores.

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GLP-1 Drugs Linked to Lower Colorectal Cancer Risk for Diabetes Patients

Med Page Today

(MedPage Today) -- Taking glucagon-like peptide 1 (GLP-1) receptor agonists for type 2 diabetes was associated with greater reductions in colorectal cancer (CRC) risk compared with several other diabetes medication classes, a nationwide cohort.

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