Sat.Jul 20, 2024 - Fri.Jul 26, 2024

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Persistent Anxiety Tied to Future Dementia

Med Page Today

(MedPage Today) -- Persistent anxiety raised the risk of all-cause dementia in older adults, a longitudinal study showed. Both chronic anxiety (HR 2.80, 95% CI 1.35-5.72, P=0.01) and new-onset anxiety (HR 3.20, 95% CI 1.40-7.45, P=0.01) were tied.

Dementia 138
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New research explores alcohol’s impact on the heart

American Heart News - Heart News

Research Highlights: Two new, basic research studies in rodents (mice and rats) analyzed the impacts that alcohol may have on the heart. In a mouse study, abnormal heart rhythms that can occur after a pattern of repeated simulation of binge drinking.

Research 135
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Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for surgery according to the guidelines is prevention of embolic events. However, uncertaint.

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Australian Medtech EMVision Unveils Backpack-Sized Brain Scanner to Empower First Responders

DAIC

EMVision's First Responder device aims to fundamentally transform stroke and traumatic brain injury outcomes for all patients, regardless of their location, by delivering sophisticated neurodiagnostic technology directly to the point of care (Photo: Business Wire) mtaschetta-millane Tue, 07/23/2024 - 10:36 July 23, 2024 — EMVision , an Australian medical device company focused on the development and commercialization of innovative portable brain scanning technology, has today unveiled its First

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Dementia Risk Drops With Shingrix Vaccine

Med Page Today

(MedPage Today) -- The recombinant shingles vaccine (Shingrix) was associated with a larger reduction in dementia than the live shingles vaccine (Zostavax), an analysis of more than 200,000 U.S. older adults showed. Over a 6-year follow-up period.

Dementia 133
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Increasing cardiac ketones may help heart failure in mouse study

American Heart News - Heart News

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Written By Magnus Nossen — with edits by Ken Grauer and Smith. The patient in today’s case is a previously healthy 40-something male who contacted EMS due to acute onset crushing chest pain. The pain was 10/10 in intensity radiating bilaterally to the shoulders and also to the left arm and neck. The below ECG was recorded. The ECG shows obvious STEMI(+) OMI due to probable proximal LAD occlusion.

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Nasal Sprays for Respiratory Infections; Paxlovid in COVID Prevention

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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The Case for Keto for Type 1 Diabetes with Andrew Koutnik, Ph.D.

Physiologically Speaking

Greetings! Today’s interview is with Andrew Koutnik, Ph.D. Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. His mission is to optimize metabolic health and patient outcomes for people living with type 1 diabetes. Andrew is unique because he himself has type 1 diabetes.

Diabetes 111
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Resuscitated from ventricular fibrillation. Should the cath lab be activated?

Dr. Smith's ECG Blog

This patient was witnessed by bystanders to collapse. They started CPR. EMS arrived and found him in Ventricular Fibrillation (VF). He was defibrillated into VT. He then underwent dual sequential defibrillation into asystole. After 1 mg of epinephrine they achieved ROSC. Total prehospital meds were epinephrine 1 mg x 3, amiodarone 300 mg and 100 mL of 8.4% sodium bicarbonate.

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Stroke recovery: It's in the genes

Science Daily - Stroke

New research has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

Stroke 107
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Empowering Patients with Educational Resources for Kidney Disease, with Mike Spigler

HCPLive

Spigler provides insight into the development of new patient-focused guidelines for managing hyperkalemia in CKD and the importance of providing patients with such resources.

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International Atherosclerosis Society Issues New White Paper Underscoring Inflammation's Role, Offering Key Recommendations

DAIC

The International Atherosclerosis Society (IAS) has released a clinical proceedings white paper outlining the role of inflammation in atherosclerosis and the importance of early intervention. The paper is part of IAS’ Clinical Proceedings, a white paper series, which offers informational resources intended to raise awareness and address unmet needs in atherosclerosis.

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A prehospital ECG in a patient with chest pain. The paramedics tell me it is normal.

Dr. Smith's ECG Blog

I was working at triage when the medics brought this patient who is 65 yo and has had chest pain for 12 hours. They recorded a prehospital ECG at 2112 and said that it was “normal”. It had already been crumpled up and put in the waste basket. So I uncrumpled it: What do you think? You need to click on it to enlarge it to view it well I was suspicious for inferior and posterior OMI (Large T-wave in aVF, slight STE in lead III with inverted T-wave in aVL, and a slightly downsloping ST with negativ

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Artificial blood vessels could improve heart bypass outcomes

Science Daily - Heart Disease

3D-printed blood vessels, which closely mimic the properties of human veins, could transform the treatment of cardiovascular diseases. Strong, flexible, gel-like tubes -- created using a novel 3D printing technology -- could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.

Outcomes 111
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Pay People, and They Will Go to Cardiac Rehab

Med Page Today

(MedPage Today) -- It might take giving people money directly for them to participate in cardiac rehabilitation, a randomized trial showed. Eligible patients in Vermont of lower socioeconomic status had cardiac rehab adherence rates shoot up if.

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FDA Accepts sNDA for Furosemide (Furoscix) in Chronic Kidney Disease

HCPLive

The sNDA for furosemide seeks to expand the indication to include the treatment of edema due to fluid overload in patients with CKD, with a PDUFA date of March 6, 2025.

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Innovative Data Featuring Nanox AI Cardiac Solution Showcased at SCCT 2024

DAIC

mtaschetta-millane Thu, 07/25/2024 - 08:55 July 25, 2024 — Nanox, an innovative medical imaging technology company, announced that the AI Cardiac Solution (HealthCCSng) of its subsidiary, Nanox.AI Ltd., was highlighted in multiple scientific presentations at the 2024 Society of Cardiovascular Computed Tomography (SCCT) Annual Meeting. “We are encouraged by the implementation of our AI cardiac solution at esteemed healthcare systems, along with the continued validation through real-world studies

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Dapagliflozin and Right Ventricular Pulmonary Vasculature in HFpEF

JAMA Cardiology

This randomized clinical trial investigates the effect of dapagliflozin on right ventricular performance and vascular load during exertion in heart failure with preserved ejection fraction (HFpEF).

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Empagliflozin protects against heart failure with preserved ejection fraction partly by inhibiting the senescence-associated STAT1–STING axis

Cardiovascular Diabetology

Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. Empagliflozin (EMPA) improves cardiovascular outcomes in HFpEF patients, but the underlying mec.

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Physical activity improves early with customized text messages in patients with heart problems

Science Daily - Heart Disease

Personalized text messages effectively promoted increased physical activity for patients after significant heart events -- such as a heart attack or surgery -- but those effects later diminished. Researcher say the results show incredible promise for simple, low cost interventions delivered through mobile technology and their potential to help prevent secondary cardiovascular events in patients.

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Positron Corporation Introduces New, Advanced Designed, Economically Priced PET-CT

DAIC

mtaschetta-millane Thu, 07/25/2024 - 08:36 July 25, 2024 — Positron Corporation , a leading molecular imaging medical device company offering PET & PET-CT imaging systems, presents its new NeuSight PET-CT 3D 64 slice scanner, available for US and North American Markets. The NeuSight PET-CT advanced technology sets a new standard in imaging and diagnostic precision, patient comfort, and operational efficiency for nuclear cardiology practices and hospitals.

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Few Youth Receive Lipid Screening, Highlighting Missed Opportunity to Reduce CVD Risk

HCPLive

Despite recommendations, an analysis of more than 3.2 million youths suggests fewer than 15% of children/adolescents receive lipid screening.

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Texas Heart Institute implants artificial heart

Becker's Hospital Review - Cardiology

"Discover the groundbreaking success of the first-in-human implantation of the BiVACOR Total Artificial Heart by the Texas Heart Institute, offering hope for he

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Brain-heart axis: Strokes change epigenetics of immune system

Science Daily - Heart Disease

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs -- such as the heart. Researchers have worked on the hypothesis that the high rate of comorbidities that develop after a stroke could have a common immunological cause. And they actually managed to find it: The origin of the dysfunctions in other parts of the body lies in the immunological memory of the blood-forming cells in bone marrow.

Stroke 107
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MedTech Startup VentriJect Selected to Demonstrate Siesmofit System to United Nations Digital Health Symposium

DAIC

VentriJect, a Danish medtech start-up seeking to revolutionize the way cardiorespiratory fitness (CRF) is measured, has been invited to the United Nations General Assembly (UNGA) in New York to demonstrate Seismofit, its portable and fast VO2 max estimation solution. The demonstration will take place at the 4th United Nations General Assembly Digital Health Symposium, to be held September 24-26 in New York.

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Serum Complement Levels Demonstrate Prognostic Value in IgA Nephropathy

HCPLive

Integrating serum C3 and C4 levels into existing prognostic scores led to better prediction accuracy and may help optimize risk stratification in patients with IgAN.

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Why You Need To Lift Heavy Things

Dr. Paddy Barrett

Physical activity is arguably the best metric for predicting longevity 1. The majority of this effect is driven by the impact of aerobic fitness. But think of aerobic fitness, likely the power output of a mechanical excavator. Necessary, but if the joints and limbs of the machine cannot transmit that power, then it is of limited use. The same is true of humans.

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Increasing Prediabetes remission for type 2 diabetes

Science Daily - Heart Disease

In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy.

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Volta Medical Enters into Joint Development Agreement with GE HealthCare to Support Electrophysiologists Treating Atrial Fibrillation

DAIC

Volta Medical has announced it has entered into a Joint Development Agreement with GE Healthcare to enhance arrhythmia procedures with artificial intelligence (AI)-driven electrophysiology technologies. The collaboration, according to a written statement issued by the company, aims to address challenges in capturing and analyzing cardiac signals to help physicians enhance patient outcomes for atrial fibrillation procedures.

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Lower Income Associated with Greater Mortality Risk in Chronic Liver Disease

HCPLive

The analysis of NHANES data found individuals with viral hepatitis and NAFLD as well as lower income and no college education were at a greater risk of mortality.

Education 105
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People Without Diabetes Make Up Growing Share of GLP-1 Users

Med Page Today

(MedPage Today) -- The proportion of new users of GLP-1 receptor agonists without type 2 diabetes markedly increased over the past decade, and particularly since 2020, according to a nationwide population-based study of prescribing trends. Overall.

Diabetes 111
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The Cardiometabolic Event of the Year: What to Expect at the 19th Annual Cardiometabolic Health Congress (CMHC) 

Cardiometabolic Health Congress

For 19 years, the Cardiometabolic Health Congress (CMHC) has worked towards a vision of a better future for clinicians, patients, and the entire health sector. This fall, we come together for the largest and most innovative cardiometabolic event in honor of the legacy of Dr. George L. Bakris. His unwavering dedication and contributions to CMHC as a renowned expert, educator, and mentor in the cardiorenal metabolic space have left an indelible mark on our community.

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FibriCheck Enters US Market with FDA Clearance

DAIC

mtaschetta-millane Wed, 07/24/2024 - 11:34 July 24, 2024 — After a rigorous investigation procedure by the Food and Drug Administration, FibriCheck is now FDA-cleared (K232804). This is an important milestone which supports FibriCheck’s further development in the U.S. market. The FDA-clearance also allows FibriCheck to improve current U.S. care pathways and to provide millions of Americans with the ability to just use their smartphone to obtain easy and accurate heart rhythm measurements.

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1 in 4 Adults in the Community Meet PTSD Criteria Following Mass Shooting

HCPLive

A new study found probable PTSD was prevalent among adults in the community after a mass shooting, with greater prevalence among those previously assaulted.

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Tiny deletion in heart muscle protein linked to long-term effects on adult atrial fibrillation

Medical Xpress - Cardiology

Millions of adults have atrial fibrillation—an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death. Many genetic mutations in the developing fetus can lead to adult atrial fibrillation, including mutations that shorten the massive protein titin in cardiac muscle cells.

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New study identifies two proteins that may contribute to stroke recurrence

Science Daily - Heart Disease

A new study has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke. The study identified CCL27 and TNFRSF14, two proteins that are associated with subsequent MACE, but not initial strokes. These proteins are known to activate inflammation, which plays a key role in the development of strokes and many chronic conditions and diseases.

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