Sat.Jul 20, 2024 - Fri.Jul 26, 2024

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Persistent Anxiety Tied to Future Dementia

Med Page Today

(MedPage Today) -- Persistent anxiety raised the risk of all-cause dementia in older adults, a longitudinal study showed. Both chronic anxiety (HR 2.80, 95% CI 1.35-5.72, P=0.01) and new-onset anxiety (HR 3.20, 95% CI 1.40-7.45, P=0.01) were tied.

Dementia 138
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New research explores alcohol’s impact on the heart

American Heart News - Heart News

Research Highlights: Two new, basic research studies in rodents (mice and rats) analyzed the impacts that alcohol may have on the heart. In a mouse study, abnormal heart rhythms that can occur after a pattern of repeated simulation of binge drinking.

Research 135
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What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Written By Magnus Nossen — with edits by Ken Grauer and Smith. The patient in today’s case is a previously healthy 40-something male who contacted EMS due to acute onset crushing chest pain. The pain was 10/10 in intensity radiating bilaterally to the shoulders and also to the left arm and neck. The below ECG was recorded. The ECG shows obvious STEMI(+) OMI due to probable proximal LAD occlusion.

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Physical activity improves early with customized text messages in patients with heart problems

Science Daily - Heart Disease

Personalized text messages effectively promoted increased physical activity for patients after significant heart events -- such as a heart attack or surgery -- but those effects later diminished. Researcher say the results show incredible promise for simple, low cost interventions delivered through mobile technology and their potential to help prevent secondary cardiovascular events in patients.

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Nasal Sprays for Respiratory Infections; Paxlovid in COVID Prevention

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Increasing cardiac ketones may help heart failure in mouse study

American Heart News - Heart News

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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Resuscitated from ventricular fibrillation. Should the cath lab be activated?

Dr. Smith's ECG Blog

This patient was witnessed by bystanders to collapse. They started CPR. EMS arrived and found him in Ventricular Fibrillation (VF). He was defibrillated into VT. He then underwent dual sequential defibrillation into asystole. After 1 mg of epinephrine they achieved ROSC. Total prehospital meds were epinephrine 1 mg x 3, amiodarone 300 mg and 100 mL of 8.4% sodium bicarbonate.

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Dementia Risk Drops With Shingrix Vaccine

Med Page Today

(MedPage Today) -- The recombinant shingles vaccine (Shingrix) was associated with a larger reduction in dementia than the live shingles vaccine (Zostavax), an analysis of more than 200,000 U.S. older adults showed. Over a 6-year follow-up period.

Dementia 133
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Stroke recovery: It's in the genes

Science Daily - Stroke

New research has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

Stroke 123
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Artificial blood vessels could improve heart bypass outcomes

Science Daily - Heart Disease

3D-printed blood vessels, which closely mimic the properties of human veins, could transform the treatment of cardiovascular diseases. Strong, flexible, gel-like tubes -- created using a novel 3D printing technology -- could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.

Outcomes 121
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Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for surgery according to the guidelines is prevention of embolic events. However, uncertaint.

Embolism 119
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Few Youth Receive Lipid Screening, Highlighting Missed Opportunity to Reduce CVD Risk

HCPLive

Despite recommendations, an analysis of more than 3.2 million youths suggests fewer than 15% of children/adolescents receive lipid screening.

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A prehospital ECG in a patient with chest pain. The paramedics tell me it is normal.

Dr. Smith's ECG Blog

I was working at triage when the medics brought this patient who is 65 yo and has had chest pain for 12 hours. They recorded a prehospital ECG at 2112 and said that it was “normal”. It had already been crumpled up and put in the waste basket. So I uncrumpled it: What do you think? You need to click on it to enlarge it to view it well I was suspicious for inferior and posterior OMI (Large T-wave in aVF, slight STE in lead III with inverted T-wave in aVL, and a slightly downsloping ST with negativ

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Pay People, and They Will Go to Cardiac Rehab

Med Page Today

(MedPage Today) -- It might take giving people money directly for them to participate in cardiac rehabilitation, a randomized trial showed. Eligible patients in Vermont of lower socioeconomic status had cardiac rehab adherence rates shoot up if.

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Brain-heart axis: Strokes change epigenetics of immune system

Science Daily - Heart Disease

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs -- such as the heart. Researchers have worked on the hypothesis that the high rate of comorbidities that develop after a stroke could have a common immunological cause. And they actually managed to find it: The origin of the dysfunctions in other parts of the body lies in the immunological memory of the blood-forming cells in bone marrow.

Stroke 117
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The Case for Keto for Type 1 Diabetes with Andrew Koutnik, Ph.D.

Physiologically Speaking

Greetings! Today’s interview is with Andrew Koutnik, Ph.D. Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. His mission is to optimize metabolic health and patient outcomes for people living with type 1 diabetes. Andrew is unique because he himself has type 1 diabetes.

Diabetes 115
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Australian Medtech EMVision Unveils Backpack-Sized Brain Scanner to Empower First Responders

DAIC

EMVision's First Responder device aims to fundamentally transform stroke and traumatic brain injury outcomes for all patients, regardless of their location, by delivering sophisticated neurodiagnostic technology directly to the point of care (Photo: Business Wire) mtaschetta-millane Tue, 07/23/2024 - 10:36 July 23, 2024 — EMVision , an Australian medical device company focused on the development and commercialization of innovative portable brain scanning technology, has today unveiled its First

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Habit-Based Interventions Increase Treatment Adherence in Gout

HCPLive

A predictable, structured routine was shown to promote consistent treatment adherence among a cohort of patients with gout.

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Increasing Prediabetes remission for type 2 diabetes

Science Daily - Heart Disease

In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy.

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Doctors who know the impact of pregnancy complications on our cardiac risk

Heart Sisters

I didn't even know until after my heart attack that a preeclampsia diagnosis during my first pregnancy meant I was at 2-3 times higher risk for heart disease.

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Patient Enrollment Commenced in Pivotal Phase 3 Trial of CardiAMP Cell Therapy for the Treatment of Ischemic Heart Failure

DAIC

mtaschetta-millane Thu, 07/25/2024 - 09:08 July 25, 2024 — BioCardia, Inc. , a global leader in cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, announced today that the confirmatory Phase 3 trial of its autologous CardiAMP cell therapy product candidate for patients with ischemic heart failure of reduced ejection fraction (HFrEF) has commenced enrollment in the United States.

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Empowering Patients with Educational Resources for Kidney Disease, with Mike Spigler

HCPLive

Spigler provides insight into the development of new patient-focused guidelines for managing hyperkalemia in CKD and the importance of providing patients with such resources.

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New study identifies two proteins that may contribute to stroke recurrence

Science Daily - Heart Disease

A new study has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke. The study identified CCL27 and TNFRSF14, two proteins that are associated with subsequent MACE, but not initial strokes. These proteins are known to activate inflammation, which plays a key role in the development of strokes and many chronic conditions and diseases.

Stroke 114
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Mainstream Medicine Still Reluctant to Order Lipid Panels for Kids

Med Page Today

(MedPage Today) -- The practice of lipid screening in children still hasn't taken off despite guideline recommendations to do so as early as age 9 years, according to a large cross-sectional study. U.S. records show that the prevalence of documented.

Document 109
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International Atherosclerosis Society Issues New White Paper Underscoring Inflammation's Role, Offering Key Recommendations

DAIC

The International Atherosclerosis Society (IAS) has released a clinical proceedings white paper outlining the role of inflammation in atherosclerosis and the importance of early intervention. The paper is part of IAS’ Clinical Proceedings, a white paper series, which offers informational resources intended to raise awareness and address unmet needs in atherosclerosis.

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FDA Accepts sNDA for Furosemide (Furoscix) in Chronic Kidney Disease

HCPLive

The sNDA for furosemide seeks to expand the indication to include the treatment of edema due to fluid overload in patients with CKD, with a PDUFA date of March 6, 2025.

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How does the brain respond to sleep apnea?

Science Daily - Heart Disease

Nearly 40 million adults in the U.S. have sleep apnea, and more than 30 million of them use a continuous positive airway pressure (CPAP) machine while sleeping. However, the machines tend to be expensive, clunky and uncomfortable -- resulting in many users giving up on using them. High blood pressure is often linked with sleep apnea because the brain works harder to regulate blood flow and breathing during sleep.

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Epidemiology of cardiometabolic health in Latin America and strategies to address disparities

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 25 July 2024; doi:10.1038/s41569-024-01058-2 Cardiovascular diseases are the leading cause of death in Latin America and the Caribbean (LAC), precipitated by the unique milieu of population growth, rapid urbanization, socioeconomic disparities and prevalent cardiometabolic risk factors. Brant and colleagues summarize trends in cardiometabolic health in LAC and discuss tailored, innovative solutions to address the growing burden of disease in the regio

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People Without Diabetes Make Up Growing Share of GLP-1 Users

Med Page Today

(MedPage Today) -- The proportion of new users of GLP-1 receptor agonists without type 2 diabetes markedly increased over the past decade, and particularly since 2020, according to a nationwide population-based study of prescribing trends. Overall.

Diabetes 109
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Physical Activity Linked to Reducing Depression Symptoms, Mediated by Pain

HCPLive

A study found the association between physical activity engagement and reduction in depression symptoms is moderated by pain.

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Method enables fast, accurate estimates of cardiovascular state to inform blood pressure management

Science Daily - Heart Disease

A new mathematical method, validated with experimental animal data, provides a fast, reliable and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care.

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Why You Need To Lift Heavy Things

Dr. Paddy Barrett

Physical activity is arguably the best metric for predicting longevity 1. The majority of this effect is driven by the impact of aerobic fitness. But think of aerobic fitness, likely the power output of a mechanical excavator. Necessary, but if the joints and limbs of the machine cannot transmit that power, then it is of limited use. The same is true of humans.

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Texas Heart Institute implants artificial heart

Becker's Hospital Review - Cardiology

"Discover the groundbreaking success of the first-in-human implantation of the BiVACOR Total Artificial Heart by the Texas Heart Institute, offering hope for he

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1 in 4 Adults in the Community Meet PTSD Criteria Following Mass Shooting

HCPLive

A new study found probable PTSD was prevalent among adults in the community after a mass shooting, with greater prevalence among those previously assaulted.

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Blood pressure high for years? Beware of stroke risk

Science Daily - Heart Disease

Years of high systolic blood pressure are linked to a greater risk for the two most common types of stroke. The results suggest that early diagnosis and sustained control of high blood pressure over the lifespan are critical to preventing stroke, especially in Black and Hispanic patients who are more likely to have uncontrolled hypertension.

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Innovative Data Featuring Nanox AI Cardiac Solution Showcased at SCCT 2024

DAIC

mtaschetta-millane Thu, 07/25/2024 - 08:55 July 25, 2024 — Nanox, an innovative medical imaging technology company, announced that the AI Cardiac Solution (HealthCCSng) of its subsidiary, Nanox.AI Ltd., was highlighted in multiple scientific presentations at the 2024 Society of Cardiovascular Computed Tomography (SCCT) Annual Meeting. “We are encouraged by the implementation of our AI cardiac solution at esteemed healthcare systems, along with the continued validation through real-world studies

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Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 22 July 2024; doi:10.1038/s41569-024-01060-8 In this Roadmap arising from an NHLBI workshop, Chew and colleagues explore the use of retinal imaging biomarkers for the prediction, diagnosis and monitoring of systemic cardiovascular diseases. The authors identify knowledge gaps and research opportunities to translate retinal imaging biomarkers into clinical practice.