Sat.Jul 27, 2024 - Fri.Aug 02, 2024

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Survey Details General Public's Eroding Trust Level with Healthcare After COVID-19

HCPLive

Trust in physicians and hospitals dropped from over 70% in 2020 to under 50% in 2024, with declines seen across all demographics, a new survey shows.

COVID-19 140
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Study identifies 18 proteins linked to heart failure, frailty

Medical Xpress - Cardiology

An analysis of blood samples from thousands of study participants, led by researchers at UT Southwestern Medical Center, revealed 18 proteins associated with both heart failure and frailty, conditions that commonly develop in late life. Their findings, published in JAMA Cardiology, could lead to new strategies to jointly predict risk, administer preventive approaches, or treat these conditions, which often occur together.

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Meningeal lymphatic CGRP signaling governs pain via cerebrospinal fluid efflux and neuroinflammation in migraine models

Journal of Clinical Investigation - Cardiology

Recently developed antimigraine therapeutics targeting calcitonin gene–related peptide (CGRP) signaling are effective, though their sites of activity remain elusive. Notably, the lymphatic vasculature is responsive to CGRP signaling, but whether meningeal lymphatic vessels (MLVs) contribute to migraine pathophysiology is unknown. Mice with lymphatic vasculature deficient in the CGRP receptor (CalcrliLEC mice) treated with nitroglycerin-mediated (NTG-mediated) chronic migraine exhibit reduced pai

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Dementia Risk Linked With Processed Red Meat

Med Page Today

(MedPage Today) -- PHILADELPHIA -- Eating two servings of processed red meat a week over decades raised the odds of subsequent dementia, a prospective study of 130,000 healthcare professionals showed. Over up to 43 years of follow-up, participants.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Top Gene Therapy News at ASRS 2024

HCPLive

A recap of the 5 most popular topics related to gene therapy in ophthalmology coming from the 42nd American Society of Retina Specialists meeting.

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Why skipping breakfast can be bad for your heart

Medical Xpress - Cardiology

Some say that breakfast is the most important meal of the day. Is it really? That's up for debate. However, skipping the first meal is not the healthiest choice and can even put someone at risk for health issues. In this Mayo Clinic Minute, Dr. Francisco Lopez-Jimenez, a Mayo Clinic cardiologist, explains why.

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How Good Is Wegovy's Heart Benefit?

Med Page Today

(MedPage Today) -- This story is the first in a series called "Ozempic: Weighing the Risks and Benefits." It was produced in part through a grant from the NIHCM Foundation. When the final results of the SELECT trial were reported last fall, investigators.

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Long COVID Linked to Significantly Worse Rheumatic Disease Activity

HCPLive

Patients with inflammatory arthritis experiencing “long COVID” reported significantly worse disease activity.

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Study reveals link between transthyretin levels and heart disease risk

Science Daily - Heart Disease

Researchers reveal the impact of transthyretin protein levels on heart disease risk.

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New insights into cellular processes after a stroke

Science Daily - Stroke

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death. As the cellular reactions to a cerebral infarction are not yet fully understood, there is a lack of possible approaches to promote the regeneration of damaged nerve tissue in the brain. A new study closes crucial gaps in our knowledge and paves the way for research into new, targeted therapeutic strategies.

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Expert Panel: Target These 14 Factors to Cut Dementia Incidence by Nearly Half

Med Page Today

(MedPage Today) -- PHILADELPHIA -- The Lancet Commission on dementia prevention, intervention, and care has raised the number of modifiable risk factors definitively linked to cognitive loss to 14, based on research conducted since its last update.

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Fathers with Type 1 Diabetes May Be More Likely to Pass on Disease than Mothers

HCPLive

An analysis of more than 11,000 people with T1D found people were more likely to report an affected father than an affected mother.

Diabetes 124
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Post-stent chest pain, revisited

Heart Sisters

Heart patients with persistent or recurrent post-stent chest pain present “an unmet clinical need”, according to the European Journal of Cardiology.

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Rapid and Accurate Prediction Model for Cardiac Arrest Treatment

DAIC

R-EDByUS score features variables using only prehospital resuscitation data. Image courtesy of Takenobu Shimada, Osaka Metropolitan University (CC BY 4.0, [link] mtaschetta-millane Mon, 07/29/2024 - 09:09 July 29, 2024 — When it comes to treating cardiac arrest, acting quickly can mean the difference between life and death. Researchers from Osaka Metropolitan University have developed a new scoring model, using only prehospital resuscitation data, that accurately predicts neurological outcomes o

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These Metals in Urine Predict Heart Disease and Death

Med Page Today

(MedPage Today) -- Traces of non-essential and essential metals in urine were associated with increased risk of cardiovascular disease (CVD) and all-cause mortality, according to the largest epidemiological study on the topic to date. Based on.

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Connections between obesity and heart failure

Science Daily - Heart Disease

A new small study has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).

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Boston Children's performs elective partial heart transplant

Becker's Hospital Review - Cardiology

Discover the groundbreaking work of Boston Children's cardiac surgeons as they perform the first elective partial heart transplant on a 4-year-old boy

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Everyday activities aren't enough to protect against stroke

Science Daily - Stroke

Research shows that the physical activities we do as we go about our lives, at work or in the home, aren't enough to protect us from having a stroke. However, exercising in our free time and using active modes of transport are associated with a decreased risk of stroke.

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Statin Use Linked to Higher Risk of Glaucoma

Med Page Today

(MedPage Today) -- Statin use was associated with a higher likelihood of glaucoma in adults with hyperlipidemia, even those whose "bad" cholesterol was at optimal levels, according to a cross-sectional, population-based study. Among over 79,000.

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Can this device prevent a stroke during a heart valve operation? New research shows potential benefit

Science Daily - Heart Disease

Recently published research shows a medical device may be beneficial for patients who have previously had a stroke and are planning to undergo a transcatheter aortic valve replacement, a type of heart valve operation.

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Risks of anxiety, suicide attempt may rise significantly after cardiovascular hospitalization

American Heart News - Heart News

Research Highlights: In this study, people hospitalized with heart disease, stroke or other cardiovascular diseases were 83% more likely to be diagnosed with a psychiatric disorder, such as anxiety and depression, and had a higher risk of suicide.

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Vaping Low Nicotine (<5%) Linked to Acute Compensatory Puffing

HCPLive

A new study found using e-cigarettes with partial nicotine reduction was linked to greater puffing time, puff duration, and total inhaled volume than 5% nicotine concentration.

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FDA Warns of Overdoses With Compounded Semaglutide

Med Page Today

(MedPage Today) -- Overdoses, some even requiring hospitalization, have occurred due to patient and physician confusion around compounded semaglutide, the FDA detailed in an alert. Adverse events reported to the agency have ranged from gastrointestinal.

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New AI tool simplifies heart monitoring: Fewer leads, same accuracy

Science Daily - Heart Disease

To diagnose heart conditions including heart attacks and heart rhythm disturbances, clinicians typically rely on 12-lead electrocardiograms (ECGs) -- complex arrangements of electrodes and wires placed around the chest and limbs to detect the heart's electrical activity. But these ECGs require specialized equipment and expertise, and not all clinics have the capability to perform them.

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University Hospitals Researcher Develops New Score System to Better Screen and Treat HFpEF Heart Failure Patients

DAIC

mtaschetta-millane Wed, 07/31/2024 - 06:00 July 31, 2024 — A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute, demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF). The study, “ An Evidence-Based Screening Tool for Heart Failure with Preserved Ejection Fraction: The HFpEF-ABA Score ," was published in the July 12 issue of Natur

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FDA Approves Paliperidone Palmitate for Schizophrenia, Schizoaffective Disorder

HCPLive

This extended-release injectable suspension for schizophrenia and schizoaffective disorder is approved as a monotherapy and as an adjunct to mood stabilizers or antidepressants.

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Hint of Alzheimer's Benefit Seen With GLP-1 Drug

Med Page Today

(MedPage Today) -- PHILADELPHIA -- A GLP-1 receptor agonist may have the ability to protect cognition in people with mild Alzheimer's dementia, data from the phase IIb ELAD trial suggested. Liraglutide (Saxenda, Victoza) showed benefit on one.

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Are cardiovascular risk factors linked to migraine?

Science Daily - Heart Disease

Having high blood pressure, specifically high diastolic blood pressure, was linked to a slightly higher odds of ever having migraine in female participants, according to a new study. Diastolic pressure is when the heart is resting between beats. However, the study did not find an increased risk between other cardiovascular risk factors and migraine.

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Kidney Dysfunction May Predict Sudden Cardiac Death in Patients with Heart Failure

DAIC

This study by Fujita Health University researchers revealed that kidney function, considered in terms of estimated glomerular filtration rate (eGFR), can be used as a predictor for SCD in patients with congestive heart failure. Image courtesy of Yoshihiro Sobue from Fujita Health University mtaschetta-millane Tue, 07/30/2024 - 09:18 July 30, 2024 — Patients with congestive heart failure (CHF) having a compromised blood supply, are at greater risk of sudden cardiac death (SCD).

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Researcher develops new score system to better screen and treat HFpEF heart failure patients

Medical Xpress - Cardiology

A novel study co-authored by a heart failure cardiologist at University Hospitals Harrington Heart & Vascular Institute demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF). The study, titled "An Evidence-Based Screening Tool for Heart Failure with Preserved Ejection Fraction: The HFpEF-ABA Score," was published in Nature Medicine.

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Midlife Blood Biomarkers Predict Late-Life Dementia

Med Page Today

(MedPage Today) -- PHILADELPHIA -- Blood biomarkers specific to Alzheimer's disease -- specifically, amyloid-beta 42/40 ratios and measures of phosphorylated tau 181 (p-tau181) -- had a relationship with subsequent dementia that started in.

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New score system to better screen and treat HFpEF heart failure patients

Science Daily - Heart Disease

A novel study co-authored by a heart failure cardiologist demonstrates the effectiveness of a newly developed scoring system in identifying patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

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Vitamin D Deficiency Prevalent Among Patients with Rheumatic Disease

HCPLive

Vitamin D insufficiency was linked to reduced muscle strength, increased pain, higher disease activity, fatigue, and worsened disease outcomes.

Outcomes 111
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CorVascular’s VasoGuard Earns FDA 510(k) Clearance

DAIC

mtaschetta-millane Mon, 07/29/2024 - 09:16 July 29, 2024 — CorVascular , a leading producer of peripheral arterial disease (PAD) / peripheral vascular disease (PVD) testing devices, today announced the U.S. Food and Drug Administration (FDA) has cleared its VasoGuard V-Series as Class II medical devices. The clearance allows CorVascular to immediately begin marketing and selling the devices to clinics, hospitals, and teaching institutions across the country, expanding access to diagnostic testi

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Alzheimer's Biomarkers Show Tantalizing Hint at Utility for Tracking Prevention

Med Page Today

(MedPage Today) -- PHILADELPHIA -- Blood tests for Alzheimer's disease biomarkers may not only be useful for clinical diagnosis but could also make it possible to test preventive therapies in people not yet showing any signs of the condition.

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Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

JAMA Cardiology

This study assess the safety and efficacy of a novel, leadless, left ventricular endocardial pacing system for patients at high risk for a cardiac resynchronization therapy upgrade or whose coronary sinus lead placement/pacing with a conventional cardiac resynchronization therapy system has failed.