Medical Xpress - Cardiology
SEPTEMBER 18, 2024
Metal exposure from environmental pollution is associated with increased buildup of calcium in the coronary arteries at a level that is comparable to traditional risk factors like smoking and diabetes, according to a study by Columbia University Mailman School of Public Health.
American Heart News - Heart News
SEPTEMBER 18, 2024
Research Highlights: People who are satisfied with their lives or feel contentment or well-being may be less likely to develop heart disease and stroke than their unsatisfied counterparts. The analysis of health records for more than 120,000 adults.
Nature Reviews - Cardiology
SEPTEMBER 16, 2024
Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01070-6 The gut microbiota has emerged as a risk factor that affects thrombotic phenotypes in several cardiovascular diseases. In this Review, Reinhardt and colleagues discuss the link between the gut microbiota, its metabolites and thromboembolic diseases, and summarize potential therapeutic interventions to modulate the gut microbiota.
Dr. Smith's ECG Blog
SEPTEMBER 18, 2024
By Smith, peer-reviewed by Interventional Cardiologist Emre Aslanger Submitted by anonymous A 53 y.o. male presents to the ED at 6:45 AM with left sided chest dull pressure that woke him up from sleep at 3am. The pain radiated to both shoulders. He arrived to the ED at around 6:45am, and stated the pain has persisted. He has had similar pain in recent weeks that has occurred at rest, but it typically goes away after about an hour.
Medical Xpress - Cardiology
SEPTEMBER 18, 2024
Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.
Med Page Today
SEPTEMBER 18, 2024
(MedPage Today) -- Exposure to metals, essential or not, was associated with the progression of subclinical atherosclerosis, according to longitudinal data from a geographically diverse cohort. Study participants with the highest urinary metal.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 17, 2024
NKT cells are innate-like T cells, recruited to the skin during viral infection, yet their contributions to long-term immune memory to viruses are unclear. We identified granzyme K, a product made by cytotoxic cells including NKT cells, as linked to induction of Th1-associated antibodies during primary dengue virus (DENV) infection in humans. We examined the role of NKT cells in vivo using DENV-infected mice lacking CD1d-dependent (CD1ddep) NKT cells.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Medical Xpress - Cardiology
SEPTEMBER 16, 2024
New evidence shows that extended estrogen suppression treatment using aromatase inhibitors for hormone receptor-positive postmenopausal breast cancer is safe; it does not increase the risk of coronary artery calcification, a sign of active coronary atherosclerosis, as some prior studies had indicated.
HCPLive
SEPTEMBER 18, 2024
A report shows only 24%, 56%, and 62% of patients meet the criteria PSIL-AT for depression according to low-bound, mid-range, and upper-bound estimates, respectively.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 17, 2024
Epithelial barriers are programmed for defense and repair but are also the site of long-term structural remodeling and disease. In general, this paradigm features epithelial stem cells (ESCs) that are called on to regenerate damaged tissues but can also be reprogrammed for detrimental remodeling. Here we identified a Wfdc21-dependent monocyte-derived dendritic cell (moDC) population that functioned as an early sentinel niche for basal ESC reprogramming in mouse models of epithelial injury after
Med Page Today
SEPTEMBER 16, 2024
(MedPage Today) -- As the American Academy of Neurology's (AAN) Brain Health Summit convenes in September, it's an opportune moment to explore the future of neurology and the role that digital quality measures (dQMs) will play in the evolution.
Medical Xpress - Cardiology
SEPTEMBER 18, 2024
People who are content with their lives or feel a sense of well-being may be less likely to develop heart disease and/or stroke compared to those with a lower sense of well-being, according to a new analysis published today (Sept. 18) in the Journal of the American Heart Association.
HCPLive
SEPTEMBER 20, 2024
Reau explains the importance of second- and third-line treatment in PBC and the potential implications of no longer having OCA after a negative FDA advisory committee meeting.
DAIC
SEPTEMBER 19, 2024
tim.hodson Thu, 09/19/2024 - 09:42 Sept. 18, 2024 – Astellas Pharma Inc. recently announced that Digitiva, a non-invasive digital health solution for heart failure management, has been listed with the U.S. Food and Drug Administration (FDA). Digitiva is classified as a Class I Software as a Medical Device (SaMD) and is exempt from 510(k) premarket submission*.
Science Daily - Heart Disease
SEPTEMBER 20, 2024
The incidence of stroke continues to increase for adults and children living with sickle cell disease (SCD) despite the Stroke Prevention Trial in Sickle Cell Anemia (STOP) establishing standards of care like transfusions and tests to measure blood flow in the brain for those deemed high-risk, according to a new study.
Medical Xpress - Cardiology
SEPTEMBER 20, 2024
A team of public health researchers at Ningxia Medical University, in China, has found, via analysis of health record data, that some regular coffee drinkers with high blood pressure may have a lower risk of developing dementia than people who do not drink coffee. Their study is published in Scientific Reports.
HCPLive
SEPTEMBER 20, 2024
Nehad Soloman, MD, FACR; Andrew Sharobeem, DO, FACR, and Sunil Patel, MD, explore the nephrologist's vital role in gout diagnosis, treatment options for gout patients with chronic kidney disease, and strategies for managing refractory gout and its associated challenges.
Science Daily - Stroke
SEPTEMBER 17, 2024
Medical researchers conducted the largest-ever genome-wide association study of all-cause dementia, finding substantial genetic overlap with vascular dementia.
Science Daily - Heart Disease
SEPTEMBER 18, 2024
Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional risk factors, according to a new study. The findings support that metals in the body are associated with the progression of plaque buildup in the arteries and potentially provide a new strategy for managing and preventing atherosclerosis.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 17, 2024
Maintaining protein homeostasis (proteostasis) requires precise control of protein folding and degradation. Failure to properly respond to stresses disrupts proteostasis, which is a hallmark of many diseases, including cataracts. Hibernators are natural cold-stress adaptors; however, little is known about how they keep a balanced proteome under conditions of drastic temperature shift.
HCPLive
SEPTEMBER 17, 2024
Better known as brittle bone disease, osteogenesis imperfecta can cause severe respiratory distress at birth and longterm effect to respiratory function. Morello shares his team's research into the cause of this effect.
Dr. Paddy Barrett
SEPTEMBER 20, 2024
Preventing heart disease is possible. You just need to know how. To prevent heart disease, you need to know what causes it, how to measure the relevant factors and what to do about them. When we say heart disease, what we really mean is plaque in the artery wall. This Is Known As Atherosclerosis. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1.
Nature Reviews - Cardiology
SEPTEMBER 16, 2024
Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01073-3 Genetic testing for inherited cardiac disease has become part of routine clinical care. In this Review, Verdonschot et al. provide an overview of the reproductive options in the context of monogenic cardiac diseases, with a focus on preimplantation genetic testing, to prepare health-care professionals for discussions with their patients.
Med Page Today
SEPTEMBER 17, 2024
(MedPage Today) -- More than half of U.S. adults with uncontrolled hypertension are unaware they have hypertension in the first place, according to a recent study in JAMA Network Open. Furthermore, more than two-thirds of those on treatment had.
HCPLive
SEPTEMBER 17, 2024
A new study revealed those who consume a moderate amount of coffee or caffeine had a 48.1% and 40.7% reduced risk for developing cardiometabolic multimorbidity.
DAIC
SEPTEMBER 16, 2024
tim.hodson Mon, 09/16/2024 - 15:15 Sept. 16, 2024 — Biotronik has received U.S. Food and Drug Administration (FDA) labeling approval of its Selectra 3D catheter in conjunction with its Solia S lead for use in left bundle branch area pacing (LBBAP). The two products represent the first and only FDA-approved stylet-driven lead and dedicated delivery catheter system approved for LBBAP.
Heart BMJ
SEPTEMBER 16, 2024
Background Cancer survivors are at increased risk of heart failure (HF). While cardiotoxicity is commonly sought at the time of cancer chemotherapy, HF develops as a result of multiple ‘hits’ over time, and there is limited evidence regarding the frequency and causes of HF during survivorship. Objectives This systematic review sought to investigate the relationship between cardiotoxic cancer therapies and HF during survivorship.
Journal of Clinical Investigation - Cardiology
SEPTEMBER 17, 2024
Obesity is linked to an increased risk of atrial fibrillation (AF) via increased oxidative stress. While NADPH oxidase 2 (NOX2), a major source of oxidative stress and reactive oxygen species (ROS) in the heart, predisposes to AF, the underlying mechanisms remain unclear. Here, we studied NOX2-mediated ROS production in obesity-mediated AF using Nox2-knockout mice and mature human induced pluripotent stem cell–derived atrial cardiomyocytes (hiPSC-aCMs).
HCPLive
SEPTEMBER 18, 2024
The new guidance reviews existing tools for weight management and provides recommendations for their use in clinical practice in patients with obesity and kidney disease.
DAIC
SEPTEMBER 17, 2024
tim.hodson Tue, 09/17/2024 - 12:34 Sept. 16, 2024 — Numerous social and structural factors, including immigration status, socioeconomic position and access to health care, contribute to differences in cardiovascular health and heart disease risk for Asian Americans, and these factors affect Asian ethnic subgroups in different ways, according to a new scientific statement published today in the American Heart Association’s journal, Circulation.
Science Daily - Heart Disease
SEPTEMBER 17, 2024
Lower socioeconomic status is associated with higher rates of death from coronary artery disease compared to higher socioeconomic status, and more than half of the disparities can be explained by four unhealthy behaviors, according to a new study.
Medical Xpress - Cardiology
SEPTEMBER 16, 2024
The discovery of a new blood group, MAL, has solved a 50-year-old mystery. Researchers from NHS Blood and Transplant (Bristol), NHSBT's International Blood Group Reference Laboratory (IBGRL) and the University of Bristol identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of rare patients lacking this blood group.
HCPLive
SEPTEMBER 16, 2024
Wilson details how her team plans to develop risk assessment models to estimate respiratory viral infection risk reductions for interventions in elementary schools.
Med Page Today
SEPTEMBER 20, 2024
(MedPage Today) -- Better imaging parameters may exist for risk stratification in nonischemic dilated cardiomyopathy (NIDCM), based on a meta-analysis. The presence and extent of late gadolinium enhancement (LGE) on cardiac MRI was a significant.
Science Daily - Heart Disease
SEPTEMBER 18, 2024
A team developed a nanoparticle technology that offers an effective solution to diagnose and treat atherosclerosis, in a non-invasive manner. Atherosclerosis is the build-up of plaque in the arteries which causes their narrowing and is a primary cause of ischemic heart disease (IHD) and ischemic stroke (IS), major contributors to deaths caused by cardiovascular diseases globally.
Nature Reviews - Cardiology
SEPTEMBER 19, 2024
Nature Reviews Cardiology, Published online: 20 September 2024; doi:10.1038/s41569-024-01079-x A study using advanced single-cell technologies has broadened our understanding of the diversity and complexity of brain endothelial cells by uncovering new endothelial subtypes and transcriptional patterns. These findings offer insights into potential therapeutic targets and emphasize the need for further research on vascular lineages and neurovascular interactions.
HCPLive
SEPTEMBER 20, 2024
Arimoclomol, in combination with miglustat, is approved to treat neurological symptoms associated with NPC in adults and children aged ≥2 years.
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