Sat.Oct 12, 2024 - Fri.Oct 18, 2024

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Type 2 Diabetes Diagnoses Emerge in Teens Months After COVID

Med Page Today

(MedPage Today) -- Children and teens had an increased risk of being diagnosed with type 2 diabetes after COVID-19 infection, a retrospective cohort study of over 600,000 youth suggested. Adolescents 10 to 19 years old had a 55% higher risk for.

COVID-19 145
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Standing more may not reduce cardiovascular disease risk, could increase circulatory issues

Medical Xpress - Cardiology

Standing has gained popularity among people looking to offset the harms of a sedentary lifestyle often caused by spending long days sitting in front of the computer, television or driving wheel. Standing desks have become a popular option among office workers, and in other industries like retail, workers may opt to stand instead of sit.

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Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture

Journal of Clinical Investigation - Cardiology

Tissue regeneration is orchestrated by macrophages that clear damaged cells and promote regenerative inflammation. How macrophages spatially adapt and diversify their functions to support the architectural requirements of actively regenerating tissue remains unknown. In this study, we reconstructed the dynamic trajectories of myeloid cells isolated from acutely injured and early stage dystrophic muscles.

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Initial prescriptions of sedatives among older stroke survivors may include too many pills

American Heart News - Heart News

Research Highlights: Within 90 days after having an ischemic (clot-caused) stroke, about 5% of stroke survivors ages 65 and older were prescribed benzodiazepines (depressants that relieve anxiety, muscle spasms, produce sedation and reduce seizures).

Strokes 122
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Hospitals with highest, lowest 30-day mortality rates for heart attack patients

Becker's Hospital Review - Cardiology

New York City-based NYU Langone hospital had the lowest 30-day mortality rate for heart attack patients in the U.S. between July 1, 2020 and June 30, 2023, according to CMS data released July 31.

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New laser light diagnostic tool quickly detects earliest sign of heart attack

Medical Xpress - Cardiology

With heart attacks, every second counts. A new blood test diagnoses them in minutes rather than hours and could be adapted as a tool for first responders and people at home.

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Lower your cholesterol early, and stick with it!

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 18 October 2024; doi:10.1038/s41569-024-01095-x Consumption of a high-fat diet leads to the progressive growth of atherosclerotic lesions. Two new studies document that, despite similar overall exposure to high-fat diet over a lifetime, an intermittent consumption of high-fat diet early in life accelerates atherosclerosis compared with continuous consumption of a high-fat diet.

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Millions of Aging Americans Are Facing Dementia by Themselves

Med Page Today

(MedPage Today) -- Sociologist Elena Portacolone, PhD, was taken aback. Many of the older adults in San Francisco she visited at home for a research project were confused when she came to the door. They'd forgotten the appointment or couldn't remember.

Dementia 116
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Cath Lab occupied. Which patient should go now (or does only one need it? Or neither?)

Dr. Smith's ECG Blog

This was sent to me by an undergraduate name Hans Helseth, who is an EKG tech, but who is an expert OMI ECG reader. He wrote most of it and I (Smith) edited. A prehospital “STEMI” activation was called on a 75 year old male ( Patient 1 ) with a history of hyperlipidemia and LAD and Cx OMI with stent placement. He arrived to the ED by helicopter at 1507, about three hours after the start of his chest pain while chopping wood around noon.

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Standing more may not reduce cardiovascular disease risk, could increase circulatory disease, research finds

Science Daily - Heart Disease

New research has shown that over the long-term, standing more compared with sitting does not improve cardiovascular health (coronary heart disease, stroke and heart failure), and could increase the risk of circulatory issues related to standing, such as varicose veins and deep vein thrombosis.

Research 109
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Poor Hepatitis D Screening in HBV Patients Impacts Survival Outcomes

HCPLive

A new study highlights suboptimal HDV screening rates in HBV-infected individuals, suggesting that treating HBV may improve survival for those with HDV coinfection.

Outcomes 119
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Serious Battery Issue Prompts Medtronic Insulin Pump Recall

Med Page Today

(MedPage Today) -- A shorter-than-expected battery life prompted a voluntary recall of certain insulin pumps from Medtronic's MiniMed 600 and 700 series, the FDA detailed on Thursday. Affecting all lots, serial numbers, and these models of the.

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1st COVID wave infections tied to stroke, heart attack risks

Becker's Hospital Review - Cardiology

People who had a confirmed case of COVID-19 during the pandemic's first wave have twice the risk of heart attack, stroke and death compared to those who were never infected, according to research funded by the National Institutes of Health.

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Providing patients with blood vessel calcification imaging results may improve cardiovascular risk control

Medical Xpress - Cardiology

In a first-ever trial, researchers from Edith Cowan University (ECU) have provided abdominal aortic calcification (AAC) imaging results to attempt to elicit behavioral changes to improve diet, physical activity, and other cardiovascular disease risk factors in older men and women.

Diet 91
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Optimizing Use and Clinical Considerations for Lipoprotein Apheresis, with Laurence Sperling, MD, and Eugenia Gianos, MD

HCPLive

In part 2 of this 3-part series, Sperling and Gianos highlight the role of lipoprotein apheresis in contemporary settings and the supporting evidence base.

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An elderly male with acute altered mental status and huge ST Elevation

Dr. Smith's ECG Blog

Written by Bobby Nicholson What do you think of this “STEMI”? A man in his 90s with a history of HTN, CKD, COPD, and OSA presented to the emergency department after being found unresponsive at home. With EMS, patient had a GCS of 3 and was saturating 60% on room air. He improved to 100% with the addition of non-rebreather, however remained altered and was intubated by EMS with ketamine and succinylcholine.

STEMI 97
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Rest, Revive, Repeat: Why Sleep is Critical for Cardiometabolic Health 

Cardiometabolic Health Congress

As healthcare providers, it’s crucial to understand the profound connection between sleep disorders and cardiometabolic health. In this week’s CMHC Pulse Blog Post, Virend K. Somers, MD, PhD , a consultant in cardiovascular medicine from the Mayo Clinic, discusses how sleep impacts both cardiovascular and metabolic outcomes. Dr. Somers also provides actionable tips on patient evaluations, management strategies, and the role of sleep in maintaining cardiometabolic health.

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High blood pressure reduces respiratory capacity due to hardening of bronchi, study shows

Medical Xpress - Cardiology

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity.

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Policy Changes Boost Survival in Pediatric Liver Transplants

HCPLive

The study found that, following gradual policy changes, children with acute liver failure requiring a transplant now face a reduced risk of both mortality and graft failure from 1989.

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'Paving the way' for improved treatment of premature aging disease

Science Daily - Heart Disease

A new article could spur the development of new and improved treatments for Hutchinson-Gilford progeria syndrome (HGPS), a rare genetic disorder with no known cure that causes accelerated aging in children.

Article 97
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Stroke Survivors Still Prescribed a 'Concerning' Amount of Benzos

Med Page Today

(MedPage Today) -- More vigilance may be needed regarding the amount of benzodiazepines being dispensed to older stroke survivors, though prescription patterns at the national level have improved in recent years. Medicare records showed that within.

Stroke 105
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Native Hawaiian and Pacific Islander adults have high CVD mortality, research reveals

Medical Xpress - Cardiology

Native Hawaiian and Pacific Islander (NHPI) adults have a high rate of cardiovascular disease (CVD) mortality, according to a study published online Oct. 15 in the Annals of Internal Medicine.

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Women with Little to No Migraine Disability Had a Lower Quality of Life Than Men

HCPLive

A study found that migraine-related disability worsens health-related quality of life, with gender-specific differences, particularly affecting women with mild disability.

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Researchers eye possible over-prescription of benzodiazepine after stroke: 5 things to know

Becker's Hospital Review - Cardiology

Despite evidence suggesting overuse of benzodiazepine in older adults can be associated with dependence, the drug is potentially being over-prescribed to older adult stroke survivors, according to a study published Oct. 17 in Stroke.

Strokes 93
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These Five Things Completely Changed My Health

Dr. Paddy Barrett

There are an infinite number of things you can do to optimise your health. But some things things, even small things, can make a huge difference. Here are five things I have found that have made a huge difference to my health. These factors may not give you the same leverage as they did for me, but ask yourself what similar small changes you can make to gain a disproportionate benefit.

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Both low and high folate levels during pregnancy linked to increased heart defects in babies

Medical Xpress - Cardiology

Pregnant women with either low or excessively high levels of folate in their blood may face a greater risk of their children developing congenital heart disease, according to a study from Guangdong Provincial People's Hospital, China.

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Matthew Cunningham, MD: 1-Year ELEVATUM Data Target Disparities in DME

HCPLive

At AAO 2024, Cunningham describes the clinical response and safety of faricimab (Vabysmo) in underrepresented populations with diabetic macular edema.

Diabetes 111
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Retinal perivascular macrophages regulate immune cell infiltration during neuroinflammation in mouse models of ocular disease

Journal of Clinical Investigation - Cardiology

The blood-retina barrier (BRB), which is disrupted in diabetic retinopathy (DR) and uveitis, is an important anatomical characteristic of the retina, regulating nutrient, waste, water, protein, and immune cell flux. The BRB is composed of endothelial cell tight junctions, pericytes, astrocyte end feet, a collagen basement membrane, and perivascular macrophages.

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Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory

Journal of Cardiothoracic Surgery

This study explores the factors contributing to the occurrence of delirium following cardiac surgery and devises nursing strategies rooted in behavior change theory.

Nursing 91
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Initial prescriptions of sedatives among older stroke survivors may include too many pills

Science Daily - Heart Disease

Initial prescriptions of benzodiazepines, a class of drugs used to treat anxiety and sleep problems after a stroke may include too many pills for adults ages 65 or older, finds new study.

Stroke 91
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Patients with Genetic HS Susceptibility Predisposed to Coronary Artery Disease, Diabetes

HCPLive

This analysis was conducted to evaluate whether genetic risk of hidradenitis suppurativa was linked to greater risk of future cardiometabolic disease.

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Do Lipid Values in Adolescence Improve CVD Risk Prediction?

Med Page Today

(MedPage Today) -- Non-laboratory-based risk factors and lipids measured in adolescence independently predicted adult cardiovascular events, according to data from seven longitudinal cohort studies. In a multivariable model using non-laboratory.

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Cannabis use disorder: from neurobiology to treatment

Journal of Clinical Investigation - Cardiology

Cannabis has been legalized for medical and recreational purposes in multiple countries. A large number of people are using cannabis and some will develop cannabis use disorder (CUD). There is a growing recognition that CUD requires specific interventions. This Review will cover this topic from a variety of perspectives, with a particular emphasis on neurobiological findings and innovative treatment approaches that are being pursued.

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Six proteins implicated in early-onset preeclampsia

Science Daily - Heart Disease

Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester. The exact cause of early-onset preeclampsia is unknown, and it is difficult to predict, prevent and diagnose. Now researchers report on six proteins that could be used as targets to diagnose and treat the condition.

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Study Highlights Respiratory Tract Infection, Wheeze Risk Factors in Preterm-Born Infants

HCPLive

This review provides an overview of current data on immune development and risk factors for preterm-born infant development of respiratory infections and wheezing.

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Coronary Revascularization Guided With Fractional Flow Reserve or Instantaneous Wave-Free Ratio

JAMA Cardiology

This study compares long-term outcomes of instantaneous wave-free ratio and fractional flow reserve-based strategies to guide revascularization.

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Distinguishing between help and harm: Helper T cell subsets and immune-related adverse events

Journal of Clinical Investigation - Cardiology

The precise conditions by which cytokines drive cancer is relevant to improving immune checkpoint inhibition (ICI) responses while decreasing toxicity. In this issue of the JCI, Kao et al. investigated T helper cell pathways in patients with solid tumors receiving ICI. The authors evaluated T cell populations, cytokine signatures, immune related adverse events (irAEs), and survival outcomes.

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