Sat.Jul 01, 2023 - Fri.Jul 07, 2023

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Global diet study challenges advice to limit high-fat dairy foods

Science Daily - Stroke

Unprocessed red meat and whole grains can be included or left out of a healthy diet, according to a study conducted in 80 countries across all inhabited continents. Diets emphasizing fruit, vegetables, dairy (mainly whole-fat), nuts, legumes and fish were linked with a lower risk of cardiovascular disease (CVD) and premature death in all world regions.

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Ask the Expert with Salim S. Virani, MD, PhD

Cardiometabolic Health Congress

Cardiometabolic Health Congress (CMHC) sat down with Dr. Salim S. Virani to find out more about his early life, how his parents encouraged his education as a means to a fulfilling career as a physician, and his opinion on the role of things like the electronic health record, genetics, social media, and more in the context of cardiometabolic medicine.

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This was texted to me by a former resident. An 80-something woman who presented with chest pain and dyspnea.

Dr. Smith's ECG Blog

This was texted to me. An 80-something woman who presented with chest pain and dyspnea. What do you think? The rhythm appears to be atrial fibrillation. In any case, it is clearly a supraventricular rhythm. There is significant ST depression in V2-V4. Is this posterior OMI? Before jumping to any conclusions about the significance of ST-T abnormalities, you must first be certain that they are not a result of (secondary to) any QRS abnormalities.

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Lack of attention for heart diseases

CineECG

Recently I came across an article which highlights the lack of attention for heart diseases. In 2019 the “our world of data” initiative published the results of a comparison study regarding the the reasons for death in the USA in the years before the pandemic hit the world. The article, written by Hanah Ritchie has the title: Does the news reflect what we die from?

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New understanding of how the brain processes and stores words we hear

Science Daily - Stroke

Neuroscientists say the brain's auditory lexicon, a catalog of verbal language, is actually located in the front of the primary auditory cortex, not in back of it -- a finding that upends a century-long understanding of this area of the brain. The new understanding matters because it may impact recovery and rehabilitation following a brain injury such as a stroke.

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Are Artificial Sweeteners Carcinogenic? WHO Report

Wellnest

Next month, the International Agency for Research on Cancer (IARC), the cancer research arm of the World Health Organization (WHO), is poised to declare one of the world’s most widely used artificial sweeteners a potential carcinogen. This move will put it in direct opposition to both regulators and the food industry. But what lead to this recent development?

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This was texted to me in real time. The patient has acute chest pain.

Dr. Smith's ECG Blog

This was texted to me in real time. The patient has acute chest pain. What do you think? Here was my answer: "Not ischemia. Chronic. Maybe HOCM or another form of LVH. I would not activate cath lab. Get serial troponins" It is a scary ECG, with a lot of ST Elevation and what appear to be hyperacute T-waves in inferior leads, and profound reciprocal ST Depression in aVL.

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How a genetic mutation can cause individuals with normal cholesterol levels to develop coronary artery disease at a young age

Science Daily - Stroke

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s -- with normal cholesterol levels and no other risk factors -- to develop coronary artery disease has now been identified,

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Implementation of Rapid Genome Sequencing for Critically Ill Infants With Complex Congenital Heart Disease

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 415-420, October 1, 2023. BACKGROUND:Rapid genome sequencing (rGS) has been shown to improve care of critically ill infants. Congenital heart disease (CHD) is a leading cause of infant mortality and is often caused by genetic disorders, yet the utility of rGS has not been prospectively studied in this population.METHODS:We conducted a prospective evaluation of rGS to improve the care of infants with complex CHD in our cardiac

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63 year old with "good story for ACS" but negative troponins.

Dr. Smith's ECG Blog

This was texted to me from a former resident, while working at a small rural hospital, with the statement: "I can’t convince myself of anything here, but he’s a 63-year-old guy with prior stents and a good story for ACS." (Chest pain or discomfort) What do you think? Here was my response: "Suspicious for inferior posterior OMI. Get serial ECGs" He then sent a previous from 4 years prior: "This is totally normal, which confirms that the first EKG does indeed represent OMI" Then the patient's ches

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Aspiration Versus Stent?Retriever as First?Line Endovascular Therapy Technique for Primary Medium and Distal Intracranial Occlusions: A Propensity?Score Matched Multicenter Analysis

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. BackgroundFor acute proximal intracranial artery occlusions, contact aspiration may be more effective than stent‐retriever for first‐line reperfusion therapy. Due to the lack of data regarding medium vessel occlusion thrombectomy, we evaluated outcomes according to first‐line technique in a large, multicenter registry.MethodsImaging, procedural, and clinical outcomes of patients with acute proximal medium vessel

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Gene Therapy for HCM: Interview with Tenaya Therapeutics Executive Medical Director Dr. Laura Robertson M.D.

HCM Beat

Recently, Cynthia Waldman of HCMBeat had the chance to discuss gene therapy and Tenaya Therapeutics' upcoming clinical trial with Dr. Laura Robertson of Tenaya.

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Contemporary Polygenic Scores of Low-Density Lipoprotein Cholesterol and Coronary Artery Disease Predict Coronary Atherosclerosis in Adolescents and Young Adults

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 480-482, October 1, 2023.

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8 systems seeking cardiology leaders

Becker's Hospital Review - Cardiology

Here are 8 health systems seeking cardiology leaders:

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Correct dosing, adherence and persistence of DOACs in atrial fibrillation and chronic kidney disease: a systematic review and meta-analysis

Open Heart

Background Chronic kidney disease (CKD) and atrial fibrillation (AF) are increasing in prevalence globally and share common risk factors. Our aim was to characterise real-world evidence on direct oral anticoagulant (DOAC) prescribing for people with AF and CKD, in terms of adherence, persistence and renal dose titration. Methods PubMed, EMBASE and CINAHL were searched from inception to June 2022.

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Cardiac Sarcoidosis Mimickers: Genetic Testing in Undifferentiated Inflammatory Cardiomyopathies

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 478-479, October 1, 2023.